ATA373284A - Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels - Google Patents

Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels

Info

Publication number: ATA373284A
Authority: AT; Austria
Prior art keywords: producing; medicinal product; hydrochloride monohydrate; cephalexin hydrochloride; crystalline cephalexin
Prior art date: 1983-12-01

Application number

AT843732A

Other languages

English (en)

Other versions

AT390616B (de

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-01

Filing date

1984-11-26

Publication date

1989-11-15

1984-11-26 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1989-11-15 Publication of ATA373284A publication Critical patent/ATA373284A/de

1990-06-11 Application granted granted Critical

1990-06-11 Publication of AT390616B publication Critical patent/AT390616B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT0373284A 1983-12-01 1984-11-26 Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels AT390616B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/556,887 US4600773A (en)	1983-12-01	1983-12-01	Crystalline cephalexin hydrochloride monohydrate

Publications (2)

Publication Number	Publication Date
ATA373284A true ATA373284A (de)	1989-11-15
AT390616B AT390616B (de)	1990-06-11

Family

ID=24223233

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0373284A AT390616B (de)	1983-12-01	1984-11-26	Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels

Country Status (46)

Country	Link
US (1)	US4600773A (de)
EP (1)	EP0143658B1 (de)
JP (1)	JPS60132990A (de)
KR (1)	KR870000527B1 (de)
AT (1)	AT390616B (de)
AU (1)	AU566080B2 (de)
BE (1)	BE901142A (de)
BG (1)	BG40966A3 (de)
BR (1)	BR8406037A (de)
CH (1)	CH661732A5 (de)
CS (1)	CS248725B2 (de)
CY (1)	CY1505A (de)
DD (1)	DD229410A5 (de)
DE (1)	DE3443065A1 (de)
DK (1)	DK158354C (de)
ES (1)	ES538019A0 (de)
FI (1)	FI80274C (de)
FR (1)	FR2555990B1 (de)
GB (1)	GB2150566B (de)
GR (1)	GR81043B (de)
GT (1)	GT198400146A (de)
HK (1)	HK92089A (de)
HU (1)	HU192516B (de)
IE (1)	IE57886B1 (de)
IL (1)	IL73639A (de)
IN (1)	IN163078B (de)
IT (1)	IT1177329B (de)
JO (1)	JO1347B1 (de)
LU (1)	LU85650A1 (de)
MA (1)	MA20279A1 (de)
MX (1)	MX159670A (de)
MY (1)	MY102966A (de)
NL (1)	NL8403588A (de)
NO (1)	NO844711L (de)
NZ (1)	NZ210357A (de)
OA (1)	OA07876A (de)
PH (1)	PH20849A (de)
PL (1)	PL146014B1 (de)
PT (1)	PT79553B (de)
SE (1)	SE464026B (de)
SG (1)	SG59789G (de)
SU (1)	SU1251807A3 (de)
YU (1)	YU45680B (de)
ZA (1)	ZA849224B (de)
ZM (1)	ZM6384A1 (de)
ZW (1)	ZW19084A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2555989B1 (fr) *	1983-12-06	1987-02-20	Bristol Myers Sa	Monohydrate de chlorocephadroxyle
JPS60142987A (ja) *	1983-12-29	1985-07-29	Mochida Pharmaceut Co Ltd	セフアロスポリン誘導体
DE150507T1 (de) *	1983-12-29	1987-02-26	Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo	Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
US4840945A (en) *	1985-04-01	1989-06-20	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
US4775751A (en) *	1985-06-03	1988-10-04	Eli Lilly & Company	Process for cephalexin hydrochloride alcoholates
US4880798A (en) *	1986-11-25	1989-11-14	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
JPS63132893A (ja) *	1986-11-25	1988-06-04	Mochida Pharmaceut Co Ltd	新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US5721229A (en) *	1995-12-26	1998-02-24	Veterinary Pharmacy Corporation	Soluble forms of cephalosporins and treatment of animals
GB9717629D0 (en)	1997-08-21	1997-10-22	Johnson Matthey Plc	Removal of residual organic solvents
AT413282B (de) *	2002-02-01	2006-01-15	Sandoz Ag	Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
US20040033262A1 (en) *	2002-08-19	2004-02-19	Orchid Health Care	Sustained release pharmaceutical composition of a cephalosporin antibiotic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3507861A (en) *	1966-09-14	1970-04-21	Lilly Co Eli	Certain 3-methyl-cephalosporin compounds
US3655656A (en) *	1970-06-04	1972-04-11	Lilly Co Eli	Crystalline cephalexin monohydrate
DE2317179C2 (de) *	1973-04-05	1982-11-25	Bristol-Myers Co., 10154 New York, N.Y.	Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
US3985747A (en) *	1974-05-24	1976-10-12	Bristol-Myers Company	Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
JPS50151890A (de) *	1974-05-30	1975-12-06
CH642850A5 (it) *	1978-10-20	1984-05-15	Ausonia Farma Srl	Composizioni farmaceutiche ad attivita antibatterica contro infezioni da germi gram-positivi e gram-negativi.
NZ206600A (en) *	1983-05-11	1987-01-23	Alza Corp	Osmotic drug delivery device

1983
- 1983-12-01 US US06/556,887 patent/US4600773A/en not_active Expired - Lifetime
1984
- 1984-09-18 ZM ZM63/84A patent/ZM6384A1/xx unknown
- 1984-11-26 BG BG067674A patent/BG40966A3/xx unknown
- 1984-11-26 YU YU199684A patent/YU45680B/sh unknown
- 1984-11-26 ZA ZA849224A patent/ZA849224B/xx unknown
- 1984-11-26 GR GR81043A patent/GR81043B/el unknown
- 1984-11-26 ZW ZW190/84A patent/ZW19084A1/xx unknown
- 1984-11-26 GT GT198400146A patent/GT198400146A/es unknown
- 1984-11-26 AT AT0373284A patent/AT390616B/de not_active IP Right Cessation
- 1984-11-26 PL PL1984250593A patent/PL146014B1/pl unknown
- 1984-11-26 SU SU843815402A patent/SU1251807A3/ru active
- 1984-11-26 IL IL73639A patent/IL73639A/xx not_active IP Right Cessation
- 1984-11-26 FI FI844631A patent/FI80274C/fi not_active IP Right Cessation
- 1984-11-26 KR KR1019840007392A patent/KR870000527B1/ko not_active Expired
- 1984-11-26 DE DE19843443065 patent/DE3443065A1/de active Granted
- 1984-11-26 SE SE8405954A patent/SE464026B/sv not_active IP Right Cessation
- 1984-11-26 MX MX5772A patent/MX159670A/es unknown
- 1984-11-26 JO JO19841347A patent/JO1347B1/en active
- 1984-11-26 NL NL8403588A patent/NL8403588A/nl not_active Application Discontinuation
- 1984-11-26 PT PT79553A patent/PT79553B/pt not_active IP Right Cessation
- 1984-11-26 CH CH5638/84A patent/CH661732A5/de not_active IP Right Cessation
- 1984-11-26 IN IN810/CAL/84A patent/IN163078B/en unknown
- 1984-11-27 IT IT23746/84A patent/IT1177329B/it active
- 1984-11-27 ES ES538019A patent/ES538019A0/es active Granted
- 1984-11-27 DD DD84269940A patent/DD229410A5/de not_active IP Right Cessation
- 1984-11-27 NO NO844711A patent/NO844711L/no unknown
- 1984-11-27 NZ NZ210357A patent/NZ210357A/en unknown
- 1984-11-27 JP JP59251491A patent/JPS60132990A/ja active Granted
- 1984-11-27 LU LU85650A patent/LU85650A1/fr unknown
- 1984-11-27 BE BE6/48038A patent/BE901142A/fr not_active IP Right Cessation
- 1984-11-27 AU AU35897/84A patent/AU566080B2/en not_active Ceased
- 1984-11-27 FR FR8418042A patent/FR2555990B1/fr not_active Expired
- 1984-11-27 PH PH31493A patent/PH20849A/en unknown
- 1984-11-27 IE IE3033/84A patent/IE57886B1/en not_active IP Right Cessation
- 1984-11-27 DK DK561284A patent/DK158354C/da not_active IP Right Cessation
- 1984-11-27 OA OA58453A patent/OA07876A/xx unknown
- 1984-11-28 CS CS849120A patent/CS248725B2/cs unknown
- 1984-11-28 MA MA20503A patent/MA20279A1/fr unknown
- 1984-11-28 HU HU844394A patent/HU192516B/hu not_active IP Right Cessation
- 1984-11-28 BR BR8406037A patent/BR8406037A/pt unknown
- 1984-11-28 EP EP84308266A patent/EP0143658B1/de not_active Expired
- 1984-11-28 CY CY1505A patent/CY1505A/xx unknown
- 1984-11-28 GB GB08430073A patent/GB2150566B/en not_active Expired
1987
- 1987-10-01 MY MYPI87002808A patent/MY102966A/en unknown
1989
- 1989-09-07 SG SG597/89A patent/SG59789G/en unknown
- 1989-11-16 HK HK920/89A patent/HK92089A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3443065A1 (de)	1985-06-20
ES8602011A1 (es)	1985-11-01
DK158354B (da)	1990-05-07
MY102966A (en)	1993-03-31
OA07876A (fr)	1986-11-20
CH661732A5 (de)	1987-08-14
SE8405954D0 (sv)	1984-11-26
KR850004765A (ko)	1985-07-27
PL146014B1 (en)	1988-12-31
LU85650A1 (fr)	1985-07-17
PL250593A1 (en)	1985-07-30
YU199684A (en)	1987-02-28
IE843033L (en)	1985-06-01
AU3589784A (en)	1985-06-06
JPH0548234B2 (de)	1993-07-20
US4600773A (en)	1986-07-15
FR2555990B1 (fr)	1986-12-26
EP0143658B1 (de)	1989-03-22
ES538019A0 (es)	1985-11-01
AU566080B2 (en)	1987-10-08
AT390616B (de)	1990-06-11
NO844711L (no)	1985-06-03
HK92089A (en)	1989-11-24
IE57886B1 (en)	1993-05-05
FI80274C (fi)	1990-05-10
GB2150566B (en)	1987-08-26
JO1347B1 (en)	1986-11-30
HUT35685A (en)	1985-07-29
GB2150566A (en)	1985-07-03
SE464026B (sv)	1991-02-25
DE3443065C2 (de)	1989-03-23
IN163078B (de)	1988-08-06
FR2555990A1 (fr)	1985-06-07
BR8406037A (pt)	1985-08-27
ZM6384A1 (en)	1985-07-22
GR81043B (en)	1985-03-27
SG59789G (en)	1989-12-29
EP0143658A2 (de)	1985-06-05
NZ210357A (en)	1988-05-30
DK561284D0 (da)	1984-11-27
MA20279A1 (fr)	1985-07-01
ZW19084A1 (en)	1985-06-12
BE901142A (fr)	1985-05-28
MX159670A (es)	1989-08-02
PT79553A (en)	1984-12-01
EP0143658A3 (en)	1986-02-12
NL8403588A (nl)	1985-07-01
PT79553B (en)	1986-12-15
SU1251807A3 (ru)	1986-08-15
CY1505A (en)	1990-08-03
IL73639A0 (en)	1985-02-28
DD229410A5 (de)	1985-11-06
SE8405954L (sv)	1985-06-02
HU192516B (en)	1987-06-29
FI844631A0 (fi)	1984-11-26
GB8430073D0 (en)	1985-01-09
PH20849A (en)	1987-05-08
CS248725B2 (en)	1987-02-12
FI80274B (fi)	1990-01-31
ZA849224B (en)	1986-07-30
YU45680B (sh)	1992-07-20
KR870000527B1 (ko)	1987-03-14
DK158354C (da)	1990-10-01
IL73639A (en)	1988-06-30
DK561284A (da)	1985-06-02
JPS60132990A (ja)	1985-07-16
IT8423746A1 (it)	1986-05-27
IT8423746A0 (it)	1984-11-27
IT1177329B (it)	1987-08-26
BG40966A3 (en)	1987-03-14
GT198400146A (es)	1986-05-20
FI844631L (fi)	1985-06-02

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DE3775614D1 (de)	1992-02-13	Teilchenzaehler und verfahren zu dessen herstellung.
ATA122485A (de)	1989-06-15	Verfahren zur herstellung von neuen 1,4-dihydro-4-oxonaphthyridin-derivaten und deren salzen
DE3751753D1 (de)	1996-04-25	Kreuzstrom-filtrationsapparat und verfahren zu dessen herstellung
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DE68922538D1 (de)	1995-06-14	Fäserchen enthaltender Streifen und Verfahren zu dessen Herstellung.
ATA373284A (de)	1989-11-15	Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels
ATE118220T1 (de)	1995-02-15	Kristallines menschliches proinsulin und verfahren zu dessen herstellung.
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DE3867918D1 (de)	1992-03-05	Wachstumspromotor fuer bifidobacterium-arten, prozess zu dessen herstellung und verfahren fuer dessen anwendung.
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Legal Events

Date	Code	Title	Description
1989-02-15	ELJ	Ceased due to non-payment of the annual fee
1996-08-15	ELJ	Ceased due to non-payment of the annual fee