AR243173A1 - Procedimiento para preparar 5-((3,5-bis(1,1-dimetiletil)-4-hidroxifenil)metilen o metil)-4-tiazolidinona y sus sales farmaceuticamente aceptables. - Google Patents
Procedimiento para preparar 5-((3,5-bis(1,1-dimetiletil)-4-hidroxifenil)metilen o metil)-4-tiazolidinona y sus sales farmaceuticamente aceptables.Info
- Publication number
- AR243173A1 AR243173A1 AR86304842A AR30484286A AR243173A1 AR 243173 A1 AR243173 A1 AR 243173A1 AR 86304842 A AR86304842 A AR 86304842A AR 30484286 A AR30484286 A AR 30484286A AR 243173 A1 AR243173 A1 AR 243173A1
- Authority
- AR
- Argentina
- Prior art keywords
- butylphenol compounds
- butylphenol
- compounds
- Prior art date
Links
- SKDGWNHUETZZCS-UHFFFAOYSA-N 2,3-ditert-butylphenol Chemical class CC(C)(C)C1=CC=CC(O)=C1C(C)(C)C SKDGWNHUETZZCS-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76416085A | 1985-08-09 | 1985-08-09 | |
| US86948886A | 1986-06-02 | 1986-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR243173A1 true AR243173A1 (es) | 1993-07-30 |
Family
ID=27117408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR86304842A AR243173A1 (es) | 1985-08-09 | 1986-08-08 | Procedimiento para preparar 5-((3,5-bis(1,1-dimetiletil)-4-hidroxifenil)metilen o metil)-4-tiazolidinona y sus sales farmaceuticamente aceptables. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0211670B1 (es) |
| JP (1) | JPH0625182B2 (es) |
| KR (1) | KR870000889B1 (es) |
| CN (1) | CN1014891B (es) |
| AR (1) | AR243173A1 (es) |
| AU (1) | AU590312B2 (es) |
| CA (1) | CA1285572C (es) |
| CY (1) | CY1619A (es) |
| DE (1) | DE3670951D1 (es) |
| DK (1) | DK169324B1 (es) |
| ES (1) | ES2001075A6 (es) |
| GR (1) | GR862081B (es) |
| HK (1) | HK94791A (es) |
| HU (1) | HU196192B (es) |
| IE (1) | IE58718B1 (es) |
| IL (1) | IL79648A (es) |
| LV (1) | LV10866B (es) |
| MX (1) | MX9203108A (es) |
| MY (1) | MY102365A (es) |
| NZ (1) | NZ217126A (es) |
| PH (1) | PH24517A (es) |
| PT (1) | PT83152B (es) |
| SG (1) | SG80391G (es) |
| SU (1) | SU1516012A3 (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8512163D0 (en) * | 1985-05-14 | 1985-06-19 | Fujisawa Pharmaceutical Co | Oxothiazolidine compound |
| US5691367A (en) * | 1985-08-09 | 1997-11-25 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US5356917A (en) * | 1985-08-09 | 1994-10-18 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US4897406A (en) * | 1987-11-13 | 1990-01-30 | Nisshin Flour Milling Co., Ltd. | Rhodanine derivatives and pharmaceutical compositions |
| US5208250A (en) * | 1988-05-25 | 1993-05-04 | Warner-Lambert Company | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents |
| IE940525L (en) * | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
| US5306822A (en) * | 1988-05-25 | 1994-04-26 | Warner-Lambert Company | Arylmethylenyl derivatives of oxazolidinone |
| NZ231534A (en) * | 1988-11-29 | 1992-02-25 | Warner Lambert Co | 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions |
| ATE139531T1 (de) * | 1989-04-07 | 1996-07-15 | Lilly Co Eli | Arylsubstituierte rhodaninderivate |
| ZA9010041B (en) * | 1989-12-21 | 1992-08-26 | Lilly Co Eli | Compounds for treating inflammatory bowel disease |
| US5216002A (en) * | 1989-12-21 | 1993-06-01 | Eli Lilly And Company | Method of treating inflammatory bowel disease |
| US5143928A (en) * | 1990-03-27 | 1992-09-01 | Warner-Lambert Company | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents |
| DE69123738T2 (de) * | 1990-04-27 | 1997-07-03 | Orion-Yhtymae Oy, Espoo | Pharmakologisch aktive catecholderivate |
| ATE157355T1 (de) * | 1991-01-21 | 1997-09-15 | Shionogi & Co | 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga |
| US5158966A (en) * | 1991-02-22 | 1992-10-27 | The University Of Colorado Foundation, Inc. | Method of treating type i diabetes |
| US5143929A (en) * | 1991-05-09 | 1992-09-01 | Warner-Lambert Company | 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents |
| EP0587377A3 (en) * | 1992-09-10 | 1994-09-21 | Lilly Co Eli | Thiazolidinone derivatives as hypoglycemic agents and for treating alzheimer's disease |
| ATE135697T1 (de) * | 1992-10-28 | 1996-04-15 | Shionogi & Co | Benzylidenderivate |
| ATE196464T1 (de) * | 1993-06-23 | 2000-10-15 | Chugai Pharmaceutical Co Ltd | Benzol-derivate, verwendbar für ischämische erkrankungen |
| US6251928B1 (en) | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
| US5476865A (en) * | 1994-07-06 | 1995-12-19 | Eli Lilly And Company | Methods of inhibiting bone loss |
| JPH10512883A (ja) * | 1995-01-23 | 1998-12-08 | イーライ・リリー・アンド・カンパニー | 多発性硬化症の治療方法 |
| EP0761657B1 (en) * | 1995-09-07 | 2000-05-24 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
| CA2255073A1 (en) * | 1996-07-11 | 1998-01-22 | Brenda Derae Shivers | Method for treating and preventing neurodegenerative disorders by administering a thiazolidinone |
| US6005142A (en) * | 1996-09-03 | 1999-12-21 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
| US6063799A (en) * | 1996-09-03 | 2000-05-16 | Eli Lilly And Company | Alternate crystal form of Tazofelone |
| AU6330999A (en) * | 1998-09-30 | 2000-04-17 | Roche Diagnostics Gmbh | Rhodanine derivatives for the treatment and prevention of metabolic bone disorders |
| AU2002953533A0 (en) * | 2002-12-24 | 2003-01-16 | Arthron Limited | Fc receptor modulating compounds and compositions |
| DE202006018406U1 (de) | 2006-12-05 | 2008-04-10 | Seda S.P.A. | Verpackung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1038050B (de) * | 1955-11-17 | 1958-09-04 | Farmaceutici Italia S A Soc | Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen |
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| JPS57130950A (en) * | 1981-02-05 | 1982-08-13 | Kanegafuchi Chem Ind Co Ltd | 3,5-di-tert-butyl-4-hydroxystyrene derivative and anti- inflammatory, analgesic, antipyretic agent and inhibitor for blood platelet aggregation |
| JPS5879944A (ja) * | 1981-11-09 | 1983-05-13 | Kanegafuchi Chem Ind Co Ltd | ３，５−ジ・タ−シヤリ−・ブチルスチレン誘導体及び抗炎症、鎮痛、解熱剤並びに血小板凝集阻害剤 |
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
-
1986
- 1986-08-06 IL IL79648A patent/IL79648A/xx not_active IP Right Cessation
- 1986-08-06 GR GR862081A patent/GR862081B/el unknown
- 1986-08-06 CA CA000515379A patent/CA1285572C/en not_active Expired - Lifetime
- 1986-08-06 PT PT83152A patent/PT83152B/pt not_active IP Right Cessation
- 1986-08-07 PH PH34111A patent/PH24517A/en unknown
- 1986-08-07 DK DK376986A patent/DK169324B1/da not_active IP Right Cessation
- 1986-08-07 NZ NZ217126A patent/NZ217126A/xx unknown
- 1986-08-07 AU AU60972/86A patent/AU590312B2/en not_active Ceased
- 1986-08-08 SU SU864027906A patent/SU1516012A3/ru active
- 1986-08-08 CN CN86105036A patent/CN1014891B/zh not_active Expired
- 1986-08-08 AR AR86304842A patent/AR243173A1/es active
- 1986-08-08 ES ES8600951A patent/ES2001075A6/es not_active Expired
- 1986-08-08 IE IE213786A patent/IE58718B1/en not_active IP Right Cessation
- 1986-08-08 DE DE8686306134T patent/DE3670951D1/de not_active Expired - Lifetime
- 1986-08-08 KR KR1019860006534A patent/KR870000889B1/ko not_active Expired
- 1986-08-08 HU HU863516A patent/HU196192B/hu not_active IP Right Cessation
- 1986-08-08 EP EP86306134A patent/EP0211670B1/en not_active Expired - Lifetime
- 1986-08-08 JP JP61187645A patent/JPH0625182B2/ja not_active Expired - Fee Related
-
1987
- 1987-09-22 MY MYPI87001858A patent/MY102365A/en unknown
-
1991
- 1991-10-04 SG SG803/91A patent/SG80391G/en unknown
- 1991-11-21 HK HK947/91A patent/HK94791A/en not_active IP Right Cessation
-
1992
- 1992-06-22 MX MX9203108A patent/MX9203108A/es unknown
- 1992-07-10 CY CY1619A patent/CY1619A/xx unknown
-
1993
- 1993-06-08 LV LVP-93-523A patent/LV10866B/lv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK376986A (da) | 1987-02-10 |
| GR862081B (en) | 1986-12-24 |
| JPS6242977A (ja) | 1987-02-24 |
| HUT42765A (en) | 1987-08-28 |
| AU6097286A (en) | 1987-02-12 |
| DE3670951D1 (de) | 1990-06-13 |
| HK94791A (en) | 1991-11-29 |
| LV10866B (en) | 1996-04-20 |
| MX9203108A (es) | 1992-07-01 |
| KR870000889B1 (ko) | 1987-05-02 |
| LV10866A (lv) | 1995-10-20 |
| CN1014891B (zh) | 1991-11-27 |
| MY102365A (en) | 1992-06-17 |
| HU196192B (en) | 1988-10-28 |
| KR870002109A (ko) | 1987-03-30 |
| EP0211670A2 (en) | 1987-02-25 |
| DK376986D0 (da) | 1986-08-07 |
| AU590312B2 (en) | 1989-11-02 |
| IL79648A0 (en) | 1986-11-30 |
| SU1516012A3 (ru) | 1989-10-15 |
| ES2001075A6 (es) | 1988-04-16 |
| PT83152A (en) | 1986-09-01 |
| DK169324B1 (da) | 1994-10-10 |
| JPH0625182B2 (ja) | 1994-04-06 |
| PT83152B (pt) | 1989-03-30 |
| CN86105036A (zh) | 1987-02-04 |
| IL79648A (en) | 1991-12-12 |
| PH24517A (en) | 1990-07-18 |
| IE58718B1 (en) | 1993-11-03 |
| CY1619A (en) | 1992-07-10 |
| EP0211670A3 (en) | 1987-05-06 |
| NZ217126A (en) | 1989-01-27 |
| SG80391G (en) | 1991-11-15 |
| EP0211670B1 (en) | 1990-05-09 |
| CA1285572C (en) | 1991-07-02 |
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