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AR229106A1 - Procedimiento para preparar derivados cis-o trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina - Google Patents

Procedimiento para preparar derivados cis-o trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina

Info

Publication number
AR229106A1
AR229106A1 AR286998A AR28699881A AR229106A1 AR 229106 A1 AR229106 A1 AR 229106A1 AR 286998 A AR286998 A AR 286998A AR 28699881 A AR28699881 A AR 28699881A AR 229106 A1 AR229106 A1 AR 229106A1
Authority
AR
Argentina
Prior art keywords
naftalenamine
tetrahydro
phenyl
derivatives
procedure
Prior art date
Application number
AR286998A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26782055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR229106(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AR229106A1 publication Critical patent/AR229106A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/14Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups
    • C07C209/16Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/21Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AR286998A 1979-11-01 1981-10-06 Procedimiento para preparar derivados cis-o trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina AR229106A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9023779A 1979-11-01 1979-11-01
US06/184,447 US4556676A (en) 1979-11-01 1980-09-05 Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine

Publications (1)

Publication Number Publication Date
AR229106A1 true AR229106A1 (es) 1983-06-15

Family

ID=26782055

Family Applications (2)

Application Number Title Priority Date Filing Date
AR283061A AR225196A1 (es) 1979-11-01 1980-10-30 Un procedimiento para preparar derivados trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina
AR286998A AR229106A1 (es) 1979-11-01 1981-10-06 Procedimiento para preparar derivados cis-o trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AR283061A AR225196A1 (es) 1979-11-01 1980-10-30 Un procedimiento para preparar derivados trans-isomericos de 4-fenil-1,2,3,4-tetrahidro-1-naftalenamina

Country Status (18)

Country Link
US (1) US4556676A (es)
EP (1) EP0028901B1 (es)
KR (1) KR840002021B1 (es)
AR (2) AR225196A1 (es)
AT (1) ATE2667T1 (es)
AU (1) AU517842B2 (es)
CA (1) CA1130816A (es)
DE (1) DE3062226D1 (es)
DK (1) DK149308C (es)
ES (2) ES496441A0 (es)
FI (1) FI68807C (es)
GR (1) GR70782B (es)
IE (1) IE50396B1 (es)
IL (1) IL61376A (es)
NO (1) NO149102C (es)
PH (1) PH15468A (es)
PT (1) PT72005B (es)
YU (2) YU41744B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
US4866208A (en) * 1981-12-21 1989-09-12 The Dow Chemical Company Meta-phenylene diamine derivatives
US4839104A (en) * 1987-06-11 1989-06-13 Pfizer, Inc. Process for preparing sertraline intermediates
US4777288A (en) * 1987-06-11 1988-10-11 Pfizer Inc. Process for preparing a 4,4-diphenylbutanoic acid derivative
FR2623802B1 (fr) * 1987-11-26 1990-05-04 Lucien Laboratoires Derives d'amino-4 trifluoromethyl-1 tetralines. leur preparation et leur application en therapeutique
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
FR2665443B1 (fr) * 1990-08-03 1992-11-06 Lucien Laboratoires Derives d'amino-4-methyl-1-tetralines, leur preparation et leur application en therapeutique.
US5082970A (en) * 1991-03-06 1992-01-21 Pfizer Inc. Process for recycling amine isomer
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
US5196607A (en) * 1992-02-14 1993-03-23 Pfizer Inc. Process for preparing ketone enantiomer
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
US5466880A (en) * 1992-09-15 1995-11-14 Pfizer Inc. Process for preparing ketone enantiomer
WO1994022495A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
DE69406553T2 (de) * 1993-11-30 1998-02-26 Pfizer Inc., New York, N.Y. Verfahren zur herstellung von chiralen tetralonen
US6410794B1 (en) 1994-12-16 2002-06-25 Uop Llc Process for preparation of pharmaceutically desired chiral tetralone from tetralones
US6455736B1 (en) 1994-12-16 2002-09-24 Uop Llc Process for preparation of pharmaceutically desired sertraline and sertraline analogs
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
IN182588B (es) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IN187170B (es) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
DE10006411C2 (de) * 2000-02-14 2002-03-07 Huf Huelsbeck & Fuerst Gmbh Elektronischer Zündanlaßschalter für Kraftfahrzeuge und Reserveschlüssel zur Betätigung desselben
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US6482440B2 (en) 2000-09-21 2002-11-19 Phase 2 Discovery, Inc. Long acting antidepressant microparticles
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
ES2431519T3 (es) * 2002-09-16 2013-11-26 Sepracor, Inc. trans-4-(3,4-Diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina para su uso en el tratamiento de trastornos del SNC
CN100584818C (zh) * 2002-09-16 2010-01-27 塞普拉科公司 用反式4-(3,4-二氯苯基)-1,2,3,4-四氢-1-萘胺及其甲酰胺治疗cns病症
AU2003272461A1 (en) * 2002-09-16 2004-04-30 Sepracor Inc. TREATMENT OF CNS DISORDERS WITH trans 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE
US8134029B2 (en) 2002-09-16 2012-03-13 Sunovion Pharmaceuticals Inc. Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
US20060014838A1 (en) * 2004-07-14 2006-01-19 Sudhakar Valluri Process for converting trans-sertraline to cis-sertraline
US20080293726A1 (en) 2005-07-06 2008-11-27 Sepracor Inc. Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders
EP2013835B1 (en) * 2006-03-31 2015-11-04 Sunovion Pharmaceuticals Inc. Preparation of chiral amides and amines
WO2007143267A2 (en) * 2006-05-31 2007-12-13 Sepracor Inc. Treatment of pain disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine and its formamide
US20100279990A1 (en) * 2006-06-13 2010-11-04 Ramot At Tel-Aviv University Ltd. Antiproliferative compounds, compositions and methods of use
EP1987815A1 (en) * 2007-05-04 2008-11-05 Schwarz Pharma Ag Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders
US20100081713A1 (en) * 2008-03-19 2010-04-01 CombinatoRx, (Singapore) Pte. Ltd. Compositions and methods for treating viral infections
EP3142999A4 (en) * 2014-05-13 2017-12-27 Sunovion Pharmaceuticals Inc. Methods and compositions of dasotraline for treatment of adhd
MX2016014768A (es) * 2014-05-13 2017-03-06 Sunovion Pharmaceuticals Inc Dosificacion de dasotralina y metodo para el tratamiento del trastorno por deficit de atencion con hiperactividad adhd.
WO2016046669A2 (en) * 2014-09-27 2016-03-31 Mohan M Alapati Compositions and methods for the treatment of depression and neurological diseases

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
GB793853A (en) * 1954-09-15 1958-04-23 Schering Ag Manufacture of new 3-amino-indanes
DE1098511B (de) * 1959-11-21 1961-02-02 Schering Ag Verfahren zur Abtrennung von analgetisch wirksamen d-1-Phenyl-3-dimethylaminoindan
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
GB1420472A (en) * 1972-09-27 1976-01-07 Pfizer Aminophenyltetralin compounds
US4045488A (en) * 1974-11-06 1977-08-30 Pfizer Inc. Aminophenyltetralin compounds
US4029731A (en) * 1974-11-06 1977-06-14 Pfizer Inc. Aminophenyltetralin compounds

Also Published As

Publication number Publication date
YU41744B (en) 1987-12-31
DE3062226D1 (en) 1983-04-07
PT72005B (en) 1981-08-31
DK462480A (da) 1981-05-02
IE802260L (en) 1981-05-01
FI68807C (fi) 1985-11-11
AU6389880A (en) 1981-05-07
IE50396B1 (en) 1986-04-16
FI803399L (fi) 1981-05-02
ES8207120A1 (es) 1982-09-01
YU3383A (en) 1983-09-30
KR840002021B1 (ko) 1984-11-05
PH15468A (en) 1983-01-24
NO149102B (no) 1983-11-07
PT72005A (en) 1980-11-01
NO803259L (no) 1981-05-04
ES8201948A1 (es) 1982-01-16
ES496441A0 (es) 1982-01-16
EP0028901A1 (en) 1981-05-20
YU42066B (en) 1988-04-30
FI68807B (fi) 1985-07-31
IL61376A0 (en) 1980-12-31
NO149102C (no) 1984-02-15
GR70782B (es) 1983-03-23
EP0028901B1 (en) 1983-03-02
IL61376A (en) 1983-10-31
KR830004201A (ko) 1983-07-06
ATE2667T1 (de) 1983-03-15
AR225196A1 (es) 1982-02-26
US4556676A (en) 1985-12-03
YU277480A (en) 1983-09-30
DK149308C (da) 1986-12-08
AU517842B2 (en) 1981-08-27
CA1130816A (en) 1982-08-31
DK149308B (da) 1986-04-28
ES506893A0 (es) 1982-09-01

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