AR203882A1 - PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES - Google Patents

PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Info

Publication number: AR203882A1
Authority: AR; Argentina
Prior art keywords: leurocristine; leurosidine; vinblastin; procedures; derivatives
Prior art date: 1973-04-02

Application number

AR257228A

Other languages

Spanish (es)

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-04-02

Filing date

1975-01-08

Publication date

1975-10-31

1975-01-08 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1975-10-31 Application granted granted Critical

1975-10-31 Publication of AR203882A1 publication Critical patent/AR203882A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Fodder In General (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AR257228A 1973-04-02 1975-01-08 PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES AR203882A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US34727573A	1973-04-02	1973-04-02

Publications (1)

Publication Number	Publication Date
AR203882A1 true AR203882A1 (en)	1975-10-31

Family

ID=23363051

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AR253105A AR204004A1 (en)	1973-04-02	1974-01-01	PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES
AR257228A AR203882A1 (en)	1973-04-02	1975-01-08	PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AR253105A AR204004A1 (en)	1973-04-02	1974-01-01	PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES

Country Status (28)

Country	Link
JP (2)	JPS5919117B2 (en)
AR (2)	AR204004A1 (en)
AT (1)	AT340605B (en)
BE (1)	BE813168A (en)
BG (3)	BG21612A3 (en)
CA (1)	CA1042428A (en)
CH (1)	CH603669A5 (en)
CS (1)	CS185223B2 (en)
CY (1)	CY1044A (en)
DD (1)	DD113538A5 (en)
DE (1)	DE2415980A1 (en)
DK (1)	DK141511B (en)
ES (2)	ES424882A1 (en)
FR (1)	FR2223044B1 (en)
GB (1)	GB1463575A (en)
HK (1)	HK20180A (en)
HU (1)	HU171572B (en)
IE (1)	IE39071B1 (en)
IL (1)	IL44415A (en)
KE (1)	KE3028A (en)
MY (1)	MY8100025A (en)
NL (1)	NL181079C (en)
PH (1)	PH13623A (en)
RO (2)	RO73524B (en)
SE (1)	SE416206B (en)
SU (4)	SU731900A3 (en)
YU (3)	YU39719B (en)
ZA (1)	ZA741674B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL48685A (en) *	1975-01-09	1980-03-31	Lilly Co Eli	Amides of vincadioline and vinblastine
GR69783B (en) *	1976-09-08	1982-07-07	Lilly Co Eli
US4096148A (en) *	1976-12-06	1978-06-20	Eli Lilly And Company	Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) *	1976-12-06	1981-03-31	Eli Lilly And Company	Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en)	1976-12-06	1981-03-31	Eli Lilly And Company	Vinca alkaloid intermediates
US4203898A (en)	1977-08-29	1980-05-20	Eli Lilly And Company	Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) *	1978-05-15	1980-04-22	Eli Lilly And Company	Bridged cathranthus alkaloid dimers
US4210584A (en)	1979-01-15	1980-07-01	Eli Lilly And Company	Vindesine synthesis
US4357334A (en)	1980-03-20	1982-11-02	Eli Lilly And Company	Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (en) *	1981-12-08	1983-09-01	Omnichem Sa	N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
OA06421A (en) *	1980-06-10	1981-09-30	Omnium Chimique Sa	Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.
FR2623504B1 (en) *	1987-11-25	1990-03-09	Adir	NOVEL N- (VINBLASTINOYL-23) DERIVATIVES OF 1-AMINO METHYLPHOSPHONIC ACID, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT76925A (en) *	1995-04-04	1998-01-28	MTA Enzimológiai Intézet	Bis-indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US5948750A (en) *	1996-10-30	1999-09-07	Merck & Co., Inc.	Conjugates useful in the treatment of prostate cancer
US6326402B1 (en)	1998-08-12	2001-12-04	Octamer, Inc.	Methods for treating viral infections using a compound capable of inhibiting microtubules
CN101146532B (en)	2005-01-21	2012-05-09	阿斯泰克斯治疗有限公司	Pharmaceutical compounds
BRPI0613783A2 (en)	2005-07-18	2011-02-01	Bipar Sciences Inc	cancer treatment
CN101534836B (en)	2006-09-05	2011-09-28	彼帕科学公司	Use of PARP inhibitors in the preparation of medicines for treating obesity
EP2059498A4 (en)	2006-09-05	2011-01-12	Bipar Sciences Inc	Treatment of cancer
US8916552B2 (en)	2006-10-12	2014-12-23	Astex Therapeutics Limited	Pharmaceutical combinations
US8883790B2 (en)	2006-10-12	2014-11-11	Astex Therapeutics Limited	Pharmaceutical combinations
NZ586125A (en)	2007-11-12	2012-12-21	Bipar Sciences Inc	Treatment of breast cancer with a parp inhibitor alone or in combination with anti-tumor agents
CN105121447B (en) *	2013-04-19	2018-02-02	暨南大学	Vinblastine derivatives and their preparation methods and applications
CN113456797B (en) *	2021-06-18	2024-03-08	暨南大学	Application of vinblastine derivatives in preparation of medicines for treating osteosarcoma and/or soft tissue sarcoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3097137A (en) *	1960-05-19	1963-07-09	Canadian Patents Dev	Vincaleukoblastine

1974
- 1974-01-01 AR AR253105A patent/AR204004A1/en active
- 1974-03-13 IL IL44415A patent/IL44415A/en unknown
- 1974-03-13 IE IE532/74A patent/IE39071B1/en unknown
- 1974-03-13 ZA ZA00741674A patent/ZA741674B/en unknown
- 1974-03-22 CA CA195,760A patent/CA1042428A/en not_active Expired
- 1974-03-25 GB GB1310174A patent/GB1463575A/en not_active Expired
- 1974-03-25 YU YU817/74A patent/YU39719B/en unknown
- 1974-03-25 CY CY1044A patent/CY1044A/en unknown
- 1974-03-29 CH CH446374A patent/CH603669A5/xx not_active IP Right Cessation
- 1974-03-29 FR FR7411519A patent/FR2223044B1/fr not_active Expired
- 1974-03-29 PH PH15676A patent/PH13623A/en unknown
- 1974-04-01 NL NLAANVRAGE7404423,A patent/NL181079C/en not_active IP Right Cessation
- 1974-04-01 SE SE7404380A patent/SE416206B/en not_active IP Right Cessation
- 1974-04-01 HU HU74EI00000538A patent/HU171572B/en unknown
- 1974-04-01 DK DK178774AA patent/DK141511B/en not_active IP Right Cessation
- 1974-04-01 CS CS7400002335A patent/CS185223B2/en unknown
- 1974-04-01 AT AT267974A patent/AT340605B/en not_active IP Right Cessation
- 1974-04-01 SU SU742013753A patent/SU731900A3/en active
- 1974-04-02 RO RO78274A patent/RO73524B/en unknown
- 1974-04-02 JP JP49037765A patent/JPS5919117B2/en not_active Expired
- 1974-04-02 BE BE1005847A patent/BE813168A/en not_active IP Right Cessation
- 1974-04-02 DE DE2415980A patent/DE2415980A1/en active Granted
- 1974-04-02 DD DD177632A patent/DD113538A5/xx unknown
- 1974-04-02 ES ES424882A patent/ES424882A1/en not_active Expired
- 1974-04-02 RO RO7498695A patent/RO77533A/en unknown
- 1974-04-02 BG BG028513A patent/BG21612A3/en unknown
- 1974-04-02 BG BG028514A patent/BG21235A3/en unknown
- 1974-04-02 BG BG026279A patent/BG22831A3/en unknown
1975
- 1975-01-08 AR AR257228A patent/AR203882A1/en active
- 1975-07-04 SU SU752151512A patent/SU784783A3/en active
- 1975-07-09 SU SU752152020A patent/SU652896A3/en active
1976
- 1976-03-31 ES ES446571A patent/ES446571A1/en not_active Expired
- 1976-12-20 SU SU762429453A patent/SU623522A3/en active
1980
- 1980-02-27 KE KE3028A patent/KE3028A/en unknown
- 1980-04-17 HK HK201/80A patent/HK20180A/en unknown
- 1980-04-25 YU YU1138/80A patent/YU39875B/en unknown
- 1980-04-25 YU YU1139/80A patent/YU39876B/en unknown
1981
- 1981-12-30 MY MY25/81A patent/MY8100025A/en unknown
1983
- 1983-12-16 JP JP58238722A patent/JPS6033837B2/en not_active Expired

Also Published As

Publication number	Publication date
ES424882A1 (en)	1976-12-16
SU623522A3 (en)	1978-09-05
RO73524A (en)	1984-10-31
CA1042428A (en)	1978-11-14
AU6671974A (en)	1975-09-18
BG21235A3 (en)	1976-03-20
IL44415A0 (en)	1974-06-30
YU113980A (en)	1982-05-31
DE2415980A1 (en)	1974-10-10
RO73524B (en)	1984-11-30
DE2415980C2 (en)	1989-11-09
ES446571A1 (en)	1977-06-16
IE39071L (en)	1974-10-02
DK141511B (en)	1980-04-08
SE416206B (en)	1980-12-08
SU784783A3 (en)	1980-11-30
JPS49128000A (en)	1974-12-07
DD113538A5 (en)	1975-06-12
NL7404423A (en)	1974-10-04
GB1463575A (en)	1977-02-02
RO77533A (en)	1982-02-01
KE3028A (en)	1980-03-28
CY1044A (en)	1980-08-01
HU171572B (en)	1978-02-28
BG22831A3 (en)	1977-04-20
HK20180A (en)	1980-04-25
SU731900A3 (en)	1980-04-30
YU39875B (en)	1985-04-30
PH13623A (en)	1980-08-07
YU113880A (en)	1982-05-31
BG21612A3 (en)	1976-07-20
BE813168A (en)	1974-10-02
AR204004A1 (en)	1975-11-12
NL181079C (en)	1987-06-16
SU652896A3 (en)	1979-03-15
FR2223044A1 (en)	1974-10-25
JPS59193895A (en)	1984-11-02
YU81774A (en)	1982-05-31
NL181079B (en)	1987-01-16
IE39071B1 (en)	1978-08-02
DK141511C (en)	1980-09-29
YU39719B (en)	1985-04-30
CH603669A5 (en)	1978-08-31
FR2223044B1 (en)	1978-06-30
YU39876B (en)	1985-04-30
ZA741674B (en)	1975-10-29
JPS5919117B2 (en)	1984-05-02
IL44415A (en)	1978-08-31
AT340605B (en)	1977-12-27
JPS6033837B2 (en)	1985-08-05
MY8100025A (en)	1981-12-31
ATA267974A (en)	1977-04-15
CS185223B2 (en)	1978-09-15

Publication	Publication Date	Title
AR204004A1 (en)	1975-11-12	PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES
AR206908A1 (en)	1976-08-31	IMPROVED PROCEDURE FOR PREPARING 1-ACILOXYCARBONYL DERIVATIVES
AR205129A1 (en)	1976-04-05	PROCEDURE FOR PREPARING NEW CHALCONA DERIVATIVES
RO68793A (en)	1980-12-30	PROCEDURE FOR PREPARING CHOPOLIAMIDE
NL7414119A (en)	1975-05-02	PROCESS FOR PREPARING 1H-TETRAZOL-5-THIOL DERIVATIVES AND 1-SUBSTITUATED 1H-TETRAZOL-5-THIOLS.
SE415261B (en)	1980-09-22	PROCEDURE FOR PREPARING POLYPEPTIDES
AR195314A1 (en)	1973-09-28	PROCEDURE FOR PREPARING PIPERIDINOALKANOL ALPHA-ARIL-4-SUBSTITUTED DERIVATIVES
SE420098B (en)	1981-09-14	PROCEDURE FOR PREPARING LINKOMYCINE DERIVATIVES
AR200387A1 (en)	1974-11-08	PROCEDURE FOR PREPARING TRIFLUOROMETHYLPHENYLPIPERAZINE DERIVATIVES
SE415354B (en)	1980-09-29	PROCEDURE FOR PREPARING Xanthine DERIVATIVES
NO151585C (en)	1985-05-08	PROCEDURE FOR PREPARING 6-DEOXYOXYTE TRACYCLINE
SE419543B (en)	1981-08-10	PROCEDURE FOR PREPARING CERTAIN STATED ISOQINOLINE DERIVATIVES
AR201506A1 (en)	1975-03-21	PROCEDURE FOR PREPARING 4-HYDROXY-3-NITROCARBSTYRILE DERIVATIVES
RO87769A (en)	1985-12-20	PROCEDURE FOR PREPARING TIAZOLIDINE DERIVATIVES
NL7415177A (en)	1975-06-03	PROCESS FOR PREPARING XANTHEEN AND THIOXANTHEEN DERIVATIVES.
AR205398A1 (en)	1976-04-30	PROCEDURE FOR PREPARING CEPHALOSPORIN DERIVATIVES
AR210132A1 (en)	1977-06-30	PROCEDURE FOR PREPARING NEW 3-AMINO-4-ACETYL-5-METHYL-PIRROL DERIVATIVES
AR200962A1 (en)	1974-12-27	PROCEDURE FOR PREPARING NEW DIGITOXYGENIN ALPHA-L-ARABINOSIDE DERIVATIVES
TR18287A (en)	1976-12-09	PROCEDURE FOR PREPARING TRIACETONAM
SE415100B (en)	1980-09-08	PROCEDURE FOR PREPARING KINUCLIDINE-QUINOLINE DERIVATIVES
SE417966B (en)	1981-04-27	PROCEDURE FOR PREPARING PYRIMIDINOAMINOMETHYL-ERGOLINE DERIVATIVES
AR206652A1 (en)	1976-08-06	PROCEDURE FOR PREPARING NEW N-AMINO-ALKYL-2-AMINOINDANE DERIVATIVES
RO67060A (en)	1982-10-26	PROCEDURE FOR PREPARING PENICILINE
AR201666A1 (en)	1975-04-08	PROCEDURE FOR PREPARING DERIVATIVES OF DIMETHYLTETRAHYDRONAFTODIOXOLIL-OXY-PROPANOLES
AR203639A1 (en)	1975-09-30	PROCEDURE FOR PREPARING N-PHENYL-N-AMINOALKYL-2-AMINO-INDANO DERIVATIVES