[go: up one dir, main page]

AR133886A1 - Compuestos novedosos - Google Patents

Compuestos novedosos

Info

Publication number
AR133886A1
AR133886A1 ARP240102527A ARP240102527A AR133886A1 AR 133886 A1 AR133886 A1 AR 133886A1 AR P240102527 A ARP240102527 A AR P240102527A AR P240102527 A ARP240102527 A AR P240102527A AR 133886 A1 AR133886 A1 AR 133886A1
Authority
AR
Argentina
Prior art keywords
compound
formula
salts
novel compounds
tautomer
Prior art date
Application number
ARP240102527A
Other languages
English (en)
Inventor
Christopher Patrick Tinworth
Laura Trulli
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of AR133886A1 publication Critical patent/AR133886A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un compuesto de la fórmula (I), un tautómero de un compuesto de la fórmula (I) o una de sus sales. Un compuesto de la fórmula (VII), un tautómero de un compuesto de la fórmula (VII) o una de sus sales. Un compuesto de la fórmula (V), un tautómero de un compuesto de la fórmula (V) o una de sus sales. Una composición farmacéutica que comprende el compuesto o uno de sus tautómeros o sales farmacéuticamente aceptables según cualquiera de las reivindicaciones precedentes y un excipiente farmacéuticamente aceptable.
ARP240102527A 2023-09-22 2024-09-20 Compuestos novedosos AR133886A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP23382956 2023-09-22

Publications (1)

Publication Number Publication Date
AR133886A1 true AR133886A1 (es) 2025-11-12

Family

ID=88237493

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP240102527A AR133886A1 (es) 2023-09-22 2024-09-20 Compuestos novedosos

Country Status (4)

Country Link
US (1) US20260001865A1 (es)
AR (1) AR133886A1 (es)
TW (1) TW202530192A (es)
WO (1) WO2025061906A1 (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL312367A (en) * 2017-01-31 2024-06-01 Arvinas Operations Inc Cereblon ligands and bifunctional compounds comprising the same
IL301626A (en) 2020-09-30 2023-05-01 Astrazeneca Ab Compounds and their use in treating cancer
CA3199074A1 (en) * 2020-10-21 2022-04-28 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of androgen receptor protein
CN117580575A (zh) * 2021-06-17 2024-02-20 南京明德新药研发有限公司 戊二酰亚胺取代的异噁唑稠环化合物及其应用
CN119301111A (zh) * 2022-03-24 2025-01-10 葛兰素史密斯克莱知识产权发展有限公司 作为protac中的降解决定子的2,4-二氧代四氢嘧啶基衍生物

Also Published As

Publication number Publication date
WO2025061906A1 (en) 2025-03-27
TW202530192A (zh) 2025-08-01
US20260001865A1 (en) 2026-01-01

Similar Documents

Publication Publication Date Title
AR133619A1 (es) Compuestos de triazina
CL2023003041A1 (es) Derivados de triazina que tienen actividad inhibidora de la replicación del virus y composición farmacéutica
MX2022011283A (es) Compuestos pirimidoheterocíclicos y aplicación de los mismos.
ECSP23002606A (es) Nuevo inhibidor de la secreción de ácido y uso del mismo
AR131493A1 (es) Inhibidores de malt1
AR131639A1 (es) Inhibidores de kif18a y usos de los mismos
CO2024003094A2 (es) Compuesto imidazocíclico y aplicación del mismo
CL2022002817A1 (es) Inhibidores de replicación del virus de inmunodeficiencia humana
MX2022002941A (es) Cristal de derivado de 1,3,5-triazina o solvato del mismo y metodo para producir el mismo.
AR128932A1 (es) Inhibidores de bcl-xl
CO2024011857A2 (es) Compuestos de uracilo n3-sustituidos como inhibidores de trpa1
AR129185A1 (es) Compuestos de 6-(pirimidin-4-il)quinolina sustituidos como inhibidores de la cinasa dependiente de ciclina
AR133886A1 (es) Compuestos novedosos
AR132764A1 (es) Inhibidores de tyk2 y sus usos
AR130303A1 (es) Compuestos de pirazolilsulfonamida y su uso terapéutico
MX2023001865A (es) Composiciones de forma de dosificación que comprenden un inhibidor de btk y mutantes de este.
AR132166A1 (es) Inhibidores de inflamasoma nlrp3 y usos de los mismos
AR129212A1 (es) Compuestos piridona como inhibidores de trpa1
MX2024004551A (es) Inhibidores de la replicacion del virus de inmunodeficiencia humana.
AR131855A1 (es) Inhibidores de quinasa dependientes de ciclina (cdk2)
AR132661A1 (es) Quinoxalinas substituidas
AR133738A1 (es) Inhibidores de cdk2 y sus usos
AR128792A1 (es) Composiciones de galnac para mejorar la biodisponibilidad de sirna
AR129588A1 (es) Inhibidores de kras
AR132167A1 (es) Inhibidores de fgfr2 y fgfr3 y usos de los mismos