AR132167A1 - Inhibidores de fgfr2 y fgfr3 y usos de los mismos - Google Patents
Inhibidores de fgfr2 y fgfr3 y usos de los mismosInfo
- Publication number
- AR132167A1 AR132167A1 ARP240100668A ARP240100668A AR132167A1 AR 132167 A1 AR132167 A1 AR 132167A1 AR P240100668 A ARP240100668 A AR P240100668A AR P240100668 A ARP240100668 A AR P240100668A AR 132167 A1 AR132167 A1 AR 132167A1
- Authority
- AR
- Argentina
- Prior art keywords
- fgfr2
- fgfr3 inhibitors
- pharmaceutically acceptable
- stereoisomer
- fgfr3
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de la fórmula (1), o una sal farmacéuticamente aceptable, o estereoisómero del mismo. Una composición farmacéutica que comprende un compuesto de acuerdo con cualquiera de las reivindicaciones 1 - 84, o una sal o estereoisómero farmacéuticamente aceptable del mismo, y al menos un excipiente farmacéuticamente aceptable.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2023082529 | 2023-03-20 | ||
| CN2023121183 | 2023-09-25 | ||
| CN2024078391 | 2024-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR132167A1 true AR132167A1 (es) | 2025-05-28 |
Family
ID=92840928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP240100668A AR132167A1 (es) | 2023-03-20 | 2024-03-19 | Inhibidores de fgfr2 y fgfr3 y usos de los mismos |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP4683921A1 (es) |
| CN (1) | CN120712269A (es) |
| AR (1) | AR132167A1 (es) |
| TW (1) | TW202442224A (es) |
| WO (1) | WO2024193542A1 (es) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA41551A (fr) * | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
| US12180207B2 (en) * | 2018-12-19 | 2024-12-31 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of FGFR tyrosine kinases |
| SG11202111327XA (en) * | 2019-05-13 | 2021-11-29 | Relay Therapeutics Inc | Fgfr inhibitors and methods of use thereof |
| CN118369322A (zh) * | 2021-12-06 | 2024-07-19 | 英矽智能科技(上海)有限公司 | 取代的单环或双环杂环化合物，其制法与医药上的用途 |
| EP4547669A1 (en) * | 2022-06-29 | 2025-05-07 | Insilico Medicine IP Limited | Inhibitors of fgfr2 and fgfr3 and uses thereof |
-
2024
- 2024-03-19 EP EP24774107.7A patent/EP4683921A1/en active Pending
- 2024-03-19 TW TW113110162A patent/TW202442224A/zh unknown
- 2024-03-19 AR ARP240100668A patent/AR132167A1/es unknown
- 2024-03-19 WO PCT/CN2024/082453 patent/WO2024193542A1/en not_active Ceased
- 2024-03-19 CN CN202480015716.0A patent/CN120712269A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW202442224A (zh) | 2024-11-01 |
| CN120712269A (zh) | 2025-09-26 |
| WO2024193542A1 (en) | 2024-09-26 |
| EP4683921A1 (en) | 2026-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DOP2022000183A (es) | Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead | |
| AR133988A1 (es) | Inhibidores de ras-pi3k y usos de los mismos | |
| AR131639A1 (es) | Inhibidores de kif18a y usos de los mismos | |
| AR127501A1 (es) | Inhibidores de la proteína que contiene el dominio de prolil hidroxilasa (phd) y usos de los mismos | |
| AR134265A1 (es) | Heterociclos y usos de los mismos | |
| AR128932A1 (es) | Inhibidores de bcl-xl | |
| UY40235A (es) | Compuestos de heteroarilo para el tratamiento del dolor | |
| AR131493A1 (es) | Inhibidores de malt1 | |
| AR128066A1 (es) | Compuesto heterocíclico de pirimidina y método de preparación y uso médico de los mismos | |
| DOP2025000009A (es) | Inhibidores de acc novedosos | |
| ECSP23084907A (es) | Inhibidores heteroaromáticos bicíclicos de la klk5 | |
| AR130602A1 (es) | Inhibidores de tead y métodos de uso de los mismos | |
| CO2026000093A2 (es) | Composiciones farmacéuticas para inhibidores de la cinasa nek7 | |
| AR132166A1 (es) | Inhibidores de inflamasoma nlrp3 y usos de los mismos | |
| CL2022002490A1 (es) | Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead | |
| AR134204A1 (es) | Nuevos compuestos como moduladores de los canales de sodio y usos de los mismos | |
| AR132167A1 (es) | Inhibidores de fgfr2 y fgfr3 y usos de los mismos | |
| AR132838A1 (es) | Inhibidores de prmt5 y usos de los mismos | |
| AR130303A1 (es) | Compuestos de pirazolilsulfonamida y su uso terapéutico | |
| AR133577A1 (es) | MODULADORES DE LA ACTIVIDAD DE TNF a Y USOS DE LOS MISMOS | |
| AR132445A1 (es) | Moduladores de nk3 y usos de los mismos | |
| AR132444A1 (es) | Moduladores de nk3 y usos de los mismos | |
| AR130979A1 (es) | Compuestos heterocilos y usos de los mismos | |
| AR134206A1 (es) | Degradantes y usos de los mismos | |
| AR131850A1 (es) | Moduladores de il-17a de imidazotriazina sustituida con lactama y usos de los mismos |