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AR131560A1 - Métodos para tratar pots mediante el uso de antagonistas de fcrn - Google Patents

Métodos para tratar pots mediante el uso de antagonistas de fcrn

Info

Publication number
AR131560A1
AR131560A1 ARP240100028A ARP240100028A AR131560A1 AR 131560 A1 AR131560 A1 AR 131560A1 AR P240100028 A ARP240100028 A AR P240100028A AR P240100028 A ARP240100028 A AR P240100028A AR 131560 A1 AR131560 A1 AR 131560A1
Authority
AR
Argentina
Prior art keywords
pots
treating
fcrn
methods
treatment
Prior art date
Application number
ARP240100028A
Other languages
English (en)
Inventor
Middendorp Joost Van
Tae Hwan Chung
Original Assignee
argenx BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by argenx BV filed Critical argenx BV
Publication of AR131560A1 publication Critical patent/AR131560A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

En la presente descripción se proporcionan métodos para tratar el síndrome de taquicardia ortostática postural (POTS) mediante el uso de una cantidad eficaz de un antagonista del receptor de Fc neonatal (FcRn) humano. En la presente descripción también se proporcionan antagonistas de FcRn para su uso en el tratamiento de POTS y para su uso en la fabricación de un medicamento para el tratamiento de POTS. Reivindicación 1: Un método para tratar el síndrome de taquicardia ortostática postural (POTS) en un sujeto que lo necesita, el método comprende administrar al sujeto una cantidad eficaz de un antagonista del receptor de Fc neonatal (FcRn) humano. Reivindicación 55: Un antagonista de FcRn para su uso en el tratamiento de POTS, en donde el tratamiento se realiza de acuerdo con el método de cualquiera de las reivindicaciones 1 - 54. Reivindicación 56: Un antagonista de FcRn para su uso en la fabricación de un medicamento para el tratamiento de POTS, en donde el tratamiento se realiza de acuerdo con el método de cualquiera de las reivindicaciones 1 - 54.
ARP240100028A 2023-01-06 2024-01-05 Métodos para tratar pots mediante el uso de antagonistas de fcrn AR131560A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202363437552P 2023-01-06 2023-01-06

Publications (1)

Publication Number Publication Date
AR131560A1 true AR131560A1 (es) 2025-04-09

Family

ID=89983623

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP240100028A AR131560A1 (es) 2023-01-06 2024-01-05 Métodos para tratar pots mediante el uso de antagonistas de fcrn

Country Status (3)

Country Link
AR (1) AR131560A1 (es)
TW (1) TW202432178A (es)
WO (1) WO2024147074A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020005981A (es) 2017-12-08 2020-08-24 Argenx Bvba Uso de antagonistas del fcrn para el tratamiento de la miastenia gravis generalizada.
MY209122A (en) 2018-06-08 2025-06-23 argenx BV Compositions and methods for treating immune thrombocytopenia
DK4087875T3 (da) 2020-01-08 2024-10-28 argenx BV Antagonister af human neonatal Fc-receptor (FcRn) til behandling af pemphigus-sygdomme
JP2025520431A (ja) 2022-06-15 2025-07-03 アルジェニクス ビーブイ Fcrn/抗原結合分子及び使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US20090252729A1 (en) 2007-05-14 2009-10-08 Farrington Graham K Single-chain Fc (scFc) regions, binding polypeptides comprising same, and methods related thereto
IL320058A (en) * 2016-07-29 2025-06-01 Momenta Pharmaceuticals Inc Fcrn antibodies and methods of use thereof
GB201618424D0 (en) * 2016-11-01 2016-12-14 Argenix Bvba Treatment of antibody mediated disease
MX2020005981A (es) 2017-12-08 2020-08-24 Argenx Bvba Uso de antagonistas del fcrn para el tratamiento de la miastenia gravis generalizada.
WO2021022249A1 (en) * 2019-08-01 2021-02-04 Momenta Pharmaceuticals, Inc. Fcrn antibodies and methods of use thereof

Also Published As

Publication number Publication date
WO2024147074A1 (en) 2024-07-11
TW202432178A (zh) 2024-08-16

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