AR131148A1 - Composiciones de insulina de acción rápida (variantes de las mismas) - Google Patents
Composiciones de insulina de acción rápida (variantes de las mismas)Info
- Publication number
- AR131148A1 AR131148A1 ARP230103156A ARP230103156A AR131148A1 AR 131148 A1 AR131148 A1 AR 131148A1 AR P230103156 A ARP230103156 A AR P230103156A AR P230103156 A ARP230103156 A AR P230103156A AR 131148 A1 AR131148 A1 AR 131148A1
- Authority
- AR
- Argentina
- Prior art keywords
- salt
- rapid
- acting insulin
- lysine
- insulin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere al campo de la ciencia farmacéutica y la medicina, es decir, a las composiciones de preparados de insulina de acción rápida. Más específicamente, la presente invención se refiere a las composiciones que comprenden una insulina de acción rápida y un aminoácido como estabilizante, donde el aminoácido puede ser seleccionado entre lisina y/o sal de la misma, o una combinación de lisina y/o sal de la misma con arginina y/o sal de la misma. Las composiciones de la invención exhiben una mejor estabilidad química y física en comparación con la técnica anterior más cercana. Reivindicación 1: Una composición para reducir el nivel de glucosa en sangre en un sujeto, en donde la composición comprende una insulina de acción rápida y un aminoácido, en donde el aminoácido es lisina o una sal de la misma, o una combinación de lisina o una sal de la misma con arginina o una sal de la misma. Reivindicación 2: La composición de la reivindicación 1, en la que la insulina de acción rápida se selecciona del grupo que consiste en insulina aspart (B28Asp), insulina lispro (B28LysB29Pro) e insulina glulisina (3BLys29BGlu).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2022130796A RU2022130796A (ru) | 2022-11-26 | Композиция быстродействующего инсулина (варианты) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR131148A1 true AR131148A1 (es) | 2025-02-19 |
Family
ID=91196432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP230103156A AR131148A1 (es) | 2022-11-26 | 2023-11-23 | Composiciones de insulina de acción rápida (variantes de las mismas) |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP4623902A1 (es) |
| CN (1) | CN120712073A (es) |
| AR (1) | AR131148A1 (es) |
| CL (1) | CL2025001546A1 (es) |
| CO (1) | CO2025008517A2 (es) |
| CR (1) | CR20250256A (es) |
| DO (1) | DOP2025000123A (es) |
| MX (1) | MX2025006079A (es) |
| WO (1) | WO2024112231A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2072596T3 (es) | 1989-12-21 | 1995-07-16 | Novo Nordisk As | Preparaciones de insulina que contienen acido nicotinico o nicotinamida. |
| AU3562195A (en) | 1994-10-04 | 1996-04-26 | Novo Nordisk A/S | Preparations containing aspb28 human insulin and nicotinamide |
| TWI394580B (zh) * | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
| PL2612677T3 (pl) * | 2009-06-26 | 2015-10-30 | Novo Nordisk As | Preparat zawierający insulinę, nikotynamid i argininę |
| NZ707160A (en) * | 2012-12-19 | 2016-08-26 | Wockhardt Ltd | A stable aqueous composition comprising human insulin or an analogue or derivative thereof |
| AU2013368990B2 (en) * | 2012-12-26 | 2017-05-18 | Wockhardt Limited | Pharmaceutical composition |
| AR098168A1 (es) * | 2013-10-25 | 2016-05-04 | Sanofi Sa | Formulación estable de insulina glulisina |
-
2023
- 2023-11-23 AR ARP230103156A patent/AR131148A1/es unknown
- 2023-11-24 CR CR20250256A patent/CR20250256A/es unknown
- 2023-11-24 WO PCT/RU2023/050272 patent/WO2024112231A1/ru not_active Ceased
- 2023-11-24 CN CN202380092609.3A patent/CN120712073A/zh active Pending
- 2023-11-24 EP EP23895130.5A patent/EP4623902A1/en active Pending
-
2025
- 2025-05-23 MX MX2025006079A patent/MX2025006079A/es unknown
- 2025-05-26 CL CL2025001546A patent/CL2025001546A1/es unknown
- 2025-05-26 DO DO2025000123A patent/DOP2025000123A/es unknown
- 2025-06-25 CO CONC2025/0008517A patent/CO2025008517A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024112231A1 (ru) | 2024-05-30 |
| MX2025006079A (es) | 2025-09-02 |
| DOP2025000123A (es) | 2025-11-30 |
| CN120712073A (zh) | 2025-09-26 |
| CO2025008517A2 (es) | 2025-07-17 |
| EP4623902A1 (en) | 2025-10-01 |
| CR20250256A (es) | 2025-10-07 |
| CL2025001546A1 (es) | 2025-09-26 |
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