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AR125013A2 - Método para mejorar la solubilidad de una sustancia que es 9-etil-6,6-dimetil-8-(4-morfolin-4-il-piperidin-1-il)-11-oxo-6,11-dihidro-5h-benzo[b]carbazol-3-carbonitrilo o una sal del mismo - Google Patents

Método para mejorar la solubilidad de una sustancia que es 9-etil-6,6-dimetil-8-(4-morfolin-4-il-piperidin-1-il)-11-oxo-6,11-dihidro-5h-benzo[b]carbazol-3-carbonitrilo o una sal del mismo

Info

Publication number
AR125013A2
AR125013A2 ARP210102994A ARP210102994A AR125013A2 AR 125013 A2 AR125013 A2 AR 125013A2 AR P210102994 A ARP210102994 A AR P210102994A AR P210102994 A ARP210102994 A AR P210102994A AR 125013 A2 AR125013 A2 AR 125013A2
Authority
AR
Argentina
Prior art keywords
substance
carbonitrile
piperidin
carbazole
benzo
Prior art date
Application number
ARP210102994A
Other languages
English (en)
Inventor
Koji Shiraki
Kentaro Furumoto
Tomoaki Hirayama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45605249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR125013(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AR125013A2 publication Critical patent/AR125013A2/es

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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Abstract

Método para mejorar la solubilidad de una sustancia que es 9-etil-6,6-dimetil-8-(4-morfolin-4-il-piperidin-1-il)-11-oxo-6,11-dihidro-5H-benzo[b]carbazol-3-carbonitrilo o una sal del mismo, que comprende agregar un coadyuvante de disolución a una composición que comprende dicha sustancia y un portador farmacéuticamente aceptable, donde el contenido de dicha sustancia es de 1 a 50 partes en peso, y donde dicho coadyuvante de disolución es laurilsulfato de sodio e hidroxipropilcelulosa, donde la relación en peso de dicha sustancia y dicho laurilsulfato de sodio es de 1:0,01 a 1:25, y la relación en peso de dicha sustancia y dicha hidroxipropilcelulosa es de 1:0,02 a 1:20.
ARP210102994A 2010-08-20 2021-10-28 Método para mejorar la solubilidad de una sustancia que es 9-etil-6,6-dimetil-8-(4-morfolin-4-il-piperidin-1-il)-11-oxo-6,11-dihidro-5h-benzo[b]carbazol-3-carbonitrilo o una sal del mismo AR125013A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010185385 2010-08-20

Publications (1)

Publication Number Publication Date
AR125013A2 true AR125013A2 (es) 2023-05-31

Family

ID=45605249

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP110103045A AR083246A1 (es) 2010-08-20 2011-08-19 Composicion que comprende compuestos tetraciclicos
ARP210102994A AR125013A2 (es) 2010-08-20 2021-10-28 Método para mejorar la solubilidad de una sustancia que es 9-etil-6,6-dimetil-8-(4-morfolin-4-il-piperidin-1-il)-11-oxo-6,11-dihidro-5h-benzo[b]carbazol-3-carbonitrilo o una sal del mismo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP110103045A AR083246A1 (es) 2010-08-20 2011-08-19 Composicion que comprende compuestos tetraciclicos

Country Status (20)

Country Link
US (5) US9365514B2 (es)
EP (2) EP3698788A1 (es)
JP (1) JP4918630B1 (es)
KR (1) KR101362589B1 (es)
CN (1) CN103052386B (es)
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AU (1) AU2011291708B2 (es)
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