AR124083A2 - Nuevo inhibidor de sglt1 - Google Patents
Nuevo inhibidor de sglt1Info
- Publication number
- AR124083A2 AR124083A2 ARP210103177A ARP210103177A AR124083A2 AR 124083 A2 AR124083 A2 AR 124083A2 AR P210103177 A ARP210103177 A AR P210103177A AR P210103177 A ARP210103177 A AR P210103177A AR 124083 A2 AR124083 A2 AR 124083A2
- Authority
- AR
- Argentina
- Prior art keywords
- new
- sglt1 inhibitor
- sglt1
- inhibitor
- hydrate
- Prior art date
Links
- 108091006277 SLC5A1 Proteins 0.000 title 1
- 102000058090 Sodium-Glucose Transporter 1 Human genes 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D309/06—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a un compuesto de fórmula (1) o hidrato del mismo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361901488P | 2013-11-08 | 2013-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR124083A2 true AR124083A2 (es) | 2023-02-08 |
Family
ID=51982747
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104010A AR098670A1 (es) | 2013-11-08 | 2014-10-24 | Inhibidor de sglt1 |
| ARP210103177A AR124083A2 (es) | 2013-11-08 | 2021-11-17 | Nuevo inhibidor de sglt1 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104010A AR098670A1 (es) | 2013-11-08 | 2014-10-24 | Inhibidor de sglt1 |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US9573970B2 (es) |
| EP (1) | EP3066108B1 (es) |
| JP (1) | JP6197113B2 (es) |
| KR (1) | KR101858881B1 (es) |
| CN (1) | CN105705509B (es) |
| AP (1) | AP2016009180A0 (es) |
| AR (2) | AR098670A1 (es) |
| AU (1) | AU2014347065B2 (es) |
| CA (1) | CA2925128C (es) |
| CL (1) | CL2016000791A1 (es) |
| CR (1) | CR20160165A (es) |
| CY (1) | CY1121096T1 (es) |
| DK (1) | DK3066108T3 (es) |
| DO (1) | DOP2016000067A (es) |
| EA (1) | EA028801B1 (es) |
| ES (1) | ES2703944T3 (es) |
| HR (1) | HRP20182061T1 (es) |
| IL (1) | IL244899B (es) |
| JO (1) | JO3485B1 (es) |
| LT (1) | LT3066108T (es) |
| MA (1) | MA39019A1 (es) |
| MX (1) | MX368174B (es) |
| MY (1) | MY192242A (es) |
| NZ (1) | NZ718118A (es) |
| PE (1) | PE20160884A1 (es) |
| PH (1) | PH12016500851B1 (es) |
| PL (1) | PL3066108T3 (es) |
| PT (1) | PT3066108T (es) |
| RS (1) | RS58050B1 (es) |
| SI (1) | SI3066108T1 (es) |
| SV (1) | SV2016005190A (es) |
| TN (1) | TN2016000112A1 (es) |
| TW (1) | TWI655198B (es) |
| UA (1) | UA118767C2 (es) |
| WO (1) | WO2015069541A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3065386A1 (en) * | 2017-06-12 | 2018-12-20 | Lignamed, Llc | Process for the preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside |
| CN110054657B (zh) * | 2018-01-18 | 2021-06-29 | 亚宝药业集团股份有限公司 | 吡喃葡萄糖取代的吡唑化合物及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU229581B1 (en) | 1999-08-31 | 2014-02-28 | Kissei Pharmaceutical | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof |
| EP1364957B1 (en) | 2001-02-26 | 2008-12-31 | Kissei Pharmaceutical Co., Ltd. | Glycopyranosyloxypyrazole derivatives and medicinal use thereof |
| WO2002098893A1 (en) | 2001-05-30 | 2002-12-12 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxypyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate therefor |
| AU2003254847B2 (en) * | 2002-08-08 | 2009-06-04 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof |
| CN100351263C (zh) * | 2002-08-08 | 2007-11-28 | 橘生药品工业株式会社 | 吡唑衍生物、含该衍生物的医药组合物、其医药用途及用于制备的中间体 |
| JP2004137245A (ja) | 2002-08-23 | 2004-05-13 | Kissei Pharmaceut Co Ltd | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
| DE102004028241B4 (de) * | 2004-06-11 | 2007-09-13 | Sanofi-Aventis Deutschland Gmbh | Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel |
| BRPI0711949A2 (pt) * | 2006-05-19 | 2012-01-17 | Taisho Pharmaceutical Co., Ltd. | composto c-fenil glicitol |
| RU2482122C2 (ru) | 2007-12-27 | 2013-05-20 | Киссеи Фармасьютикал Ко., Лтд. | Моносебацинат производного пиразола |
| AU2010216634B2 (en) | 2009-02-23 | 2014-07-10 | Taisho Pharmaceutical Co., Ltd. | 4 -isopropylphenyl glucitol compounds as SGLT1 inhibitors |
| BR112012007349A2 (pt) * | 2009-10-02 | 2019-09-24 | Sanofi Sa | uso de composto com atividade inibidora de sglt-1/sglt-2 para produção de medicamentos para tratamento de doenças ósseas. |
| US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| UA113086C2 (xx) * | 2012-05-10 | 2016-12-12 | Піразольні сполуки як інгібітори sglt1 |
-
2014
- 2014-10-24 AR ARP140104010A patent/AR098670A1/es not_active Application Discontinuation
- 2014-10-26 JO JOP/2014/0310A patent/JO3485B1/ar active
- 2014-10-27 TW TW103137067A patent/TWI655198B/zh active
- 2014-10-30 PE PE2016000546A patent/PE20160884A1/es unknown
- 2014-10-30 AP AP2016009180A patent/AP2016009180A0/en unknown
- 2014-10-30 TN TN2016000112A patent/TN2016000112A1/en unknown
- 2014-10-30 EA EA201690749A patent/EA028801B1/ru not_active IP Right Cessation
- 2014-10-30 MA MA39019A patent/MA39019A1/fr unknown
- 2014-10-30 WO PCT/US2014/063161 patent/WO2015069541A1/en not_active Ceased
- 2014-10-30 MX MX2016005999A patent/MX368174B/es active IP Right Grant
- 2014-10-30 AU AU2014347065A patent/AU2014347065B2/en active Active
- 2014-10-30 ES ES14802974T patent/ES2703944T3/es active Active
- 2014-10-30 KR KR1020167011764A patent/KR101858881B1/ko active Active
- 2014-10-30 PL PL14802974T patent/PL3066108T3/pl unknown
- 2014-10-30 LT LTEP14802974.7T patent/LT3066108T/lt unknown
- 2014-10-30 NZ NZ718118A patent/NZ718118A/en unknown
- 2014-10-30 CA CA2925128A patent/CA2925128C/en active Active
- 2014-10-30 RS RS20181382A patent/RS58050B1/sr unknown
- 2014-10-30 EP EP14802974.7A patent/EP3066108B1/en active Active
- 2014-10-30 US US15/026,427 patent/US9573970B2/en active Active
- 2014-10-30 CN CN201480060924.9A patent/CN105705509B/zh active Active
- 2014-10-30 DK DK14802974.7T patent/DK3066108T3/da active
- 2014-10-30 PT PT14802974T patent/PT3066108T/pt unknown
- 2014-10-30 MY MYPI2016701635A patent/MY192242A/en unknown
- 2014-10-30 JP JP2016526778A patent/JP6197113B2/ja active Active
- 2014-10-30 SI SI201430941T patent/SI3066108T1/sl unknown
- 2014-10-30 HR HRP20182061TT patent/HRP20182061T1/hr unknown
- 2014-10-30 UA UAA201603973A patent/UA118767C2/uk unknown
-
2016
- 2016-03-17 DO DO2016000067A patent/DOP2016000067A/es unknown
- 2016-04-04 IL IL24489916A patent/IL244899B/en active IP Right Grant
- 2016-04-06 CL CL2016000791A patent/CL2016000791A1/es unknown
- 2016-04-06 CR CR20160165A patent/CR20160165A/es unknown
- 2016-05-03 SV SV2016005190A patent/SV2016005190A/es unknown
- 2016-05-06 PH PH12016500851A patent/PH12016500851B1/en unknown
-
2018
- 2018-12-12 CY CY181101334T patent/CY1121096T1/el unknown
-
2021
- 2021-11-17 AR ARP210103177A patent/AR124083A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR110381A2 (es) | Inhibidores biarilo de tirosina cinasa de bruton | |
| CY1119105T1 (el) | Παραγωγα διπυραζολιου ως αναστολεις jak | |
| CR20140468A (es) | Inhibidores de diacilglicerol aciltransferasa 2 | |
| CR20150418A (es) | Compuestos de tetrahidropirrolotiazina | |
| CR20150541A (es) | Compuestos y composiciones nuevos para la inhibición de fasn | |
| MX378288B (es) | Inhibidores de pirimidina del fgfr4. | |
| EA201591634A1 (ru) | Дигидропиридопиримидиновые соединения | |
| BR112016029333A2 (pt) | síntese de compostos de carbamoilpiridona policíclico | |
| CR20140306A (es) | Fluormetil -5,6-dihidro-4h-[1,3] oxazinas | |
| CL2016001349A1 (es) | Uso de derivados de bencimidazol-prolina | |
| MA39843A (fr) | Pyridine-2-amides utiles comme agonistes de cb2 | |
| AR095097A1 (es) | Compuestos de fenoxietoxi | |
| SG10201805896SA (en) | PPARγ AGONISTS FOR TREATMENT OF MULTIPLE SCLEROSIS | |
| MX2021012440A (es) | Farmacos precursores de oxabicicloheptanos. | |
| EA201591915A1 (ru) | Соединения феноксиэтил дигидро-1h-изохинолина | |
| CR20150417A (es) | Compuestos de azetidiniloxifenilpirrolidina | |
| CY1121116T1 (el) | Νεα μεθοδος για την συνθεση αγομελατινης | |
| MX2015016332A (es) | Inhibidores de alk biciclicos fusionados. | |
| MX2018003903A (es) | Compuesto biciclico y uso del mismo para inhibicion de suv39h2. | |
| AR124083A2 (es) | Nuevo inhibidor de sglt1 | |
| MX2015014728A (es) | Sintesis de inhibidores de beta secretasa (bace). | |
| MX2016007982A (es) | Nuevo compuesto para el tratamiento de hipoglucemia severa. | |
| MX2016007984A (es) | Nuevo compuesto para el tratamiento de hipoglucemia severa. | |
| CU20130092A7 (es) | Nuevo procedimiento para la síntesis de la agomelatina | |
| CY1119540T1 (el) | Υποκατασταθεντα απο γλυκοπυρανοσυλιο παραγωγα ινδολο-ουριας και η χρηση τους ως αναστολεις sglt |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |