AR110377A1 - Vectores recombinantes de hvt que expresan múltiples antígenos de patógenos de aves y sus usos - Google Patents
Vectores recombinantes de hvt que expresan múltiples antígenos de patógenos de aves y sus usosInfo
- Publication number
- AR110377A1 AR110377A1 ARP170103521A ARP170103521A AR110377A1 AR 110377 A1 AR110377 A1 AR 110377A1 AR P170103521 A ARP170103521 A AR P170103521A AR P170103521 A ARP170103521 A AR P170103521A AR 110377 A1 AR110377 A1 AR 110377A1
- Authority
- AR
- Argentina
- Prior art keywords
- antigen
- virus
- infectious
- disease virus
- polynucleotide
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 11
- 102000036639 antigens Human genes 0.000 title abstract 11
- 108091007433 antigens Proteins 0.000 title abstract 11
- 239000013598 vector Substances 0.000 title abstract 3
- 244000052769 pathogen Species 0.000 title abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 7
- 108091033319 polynucleotide Proteins 0.000 abstract 7
- 239000002157 polynucleotide Substances 0.000 abstract 7
- 208000015181 infectious disease Diseases 0.000 abstract 5
- 230000002458 infectious effect Effects 0.000 abstract 5
- 241000701063 Gallid alphaherpesvirus 1 Species 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 4
- 241000711404 Avian avulavirus 1 Species 0.000 abstract 3
- 206010006811 Bursitis Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102100022717 Atypical chemokine receptor 1 Human genes 0.000 abstract 2
- 101000678879 Homo sapiens Atypical chemokine receptor 1 Proteins 0.000 abstract 2
- 206010044302 Tracheitis Diseases 0.000 abstract 2
- 201000009837 laryngotracheitis Diseases 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 241000271566 Aves Species 0.000 abstract 1
- 241001502481 Meleagrid alphaherpesvirus 1 Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
Classifications
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
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- C12N15/09—Recombinant DNA-technology
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Abstract
Reivindicación 1: Una composición o vacuna caracterizada porque comprende uno o más vectores del herpesvirus de pavos (HVT) recombinantes que comprende por lo menos uno o más polinucleótidos heterólogos que codifican por lo menos un antígeno de un patógeno aviar. Reivindicación 2: La composición o vacuna de la reivindicación 1, caracterizada porque el vector HVT comprende: 1) dos polinucleótidos heterólogos, y donde el primer polinucleótido comprende un polinucleótido que codifica un polipéptido seleccionado del grupo que consiste en un antígeno VP2 del virus de la enfermedad de bursitis infecciosa (IBDV), un antígeno de la glicoproteína D (gD) del virus de la laringotraqueítis infecciosa (ILTV) y un antígeno F del virus de la enfermedad de Newcastle (NDV-F), y en donde el segundo polinucleótido comprende un polinucleótido que codifica un polipéptido seleccionado del grupo que consiste en un antígeno VP2 del virus de la enfermedad de bursitis infecciosa (IBDV), un antígeno de la glicoproteína D (gD) del virus de la laringotraqueítis infecciosa (ILTV) y un antígeno F del virus de la enfermedad de Newcastle (NDV-F); o 2) un polinucleótido heterólogo que codifica un polipéptido seleccionado del grupo que consiste en un antígeno VP2 del virus de la enfermedad de bursitis infecciosa (IBDV), un antígeno de la glicoproteína D (gD) del virus de la laringotraqueítis infecciosa (ILTV) y un antígeno F del virus de la enfermedad de Newcastle (NDV-F).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662433842P | 2016-12-14 | 2016-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR110377A1 true AR110377A1 (es) | 2019-03-20 |
Family
ID=60915665
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170103521A AR110377A1 (es) | 2016-12-14 | 2017-12-14 | Vectores recombinantes de hvt que expresan múltiples antígenos de patógenos de aves y sus usos |
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| Country | Link |
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| US (5) | US10323257B2 (es) |
| EP (5) | EP3854415A1 (es) |
| JP (1) | JP7217703B2 (es) |
| KR (3) | KR102780119B1 (es) |
| CN (3) | CN117357642A (es) |
| AR (1) | AR110377A1 (es) |
| BR (1) | BR112019012280A2 (es) |
| CA (1) | CA3047101A1 (es) |
| CL (1) | CL2019001640A1 (es) |
| CO (1) | CO2019006820A2 (es) |
| EC (1) | ECSP19049787A (es) |
| ES (1) | ES2936117T3 (es) |
| HR (1) | HRP20221527T1 (es) |
| HU (1) | HUE060926T2 (es) |
| MA (2) | MA49874A (es) |
| MX (2) | MX385359B (es) |
| PE (1) | PE20191701A1 (es) |
| PH (1) | PH12019501366A1 (es) |
| PL (1) | PL3554536T3 (es) |
| PT (1) | PT3554536T (es) |
| RU (1) | RU2752836C2 (es) |
| WO (1) | WO2018112051A1 (es) |
| ZA (1) | ZA201903801B (es) |
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| HUE060926T2 (hu) | 2016-12-14 | 2023-04-28 | Boehringer Ingelheim Animal Health Usa Inc | Madárpatogének több antigénjét expresszáló, rekombináns HVT-vektorok és azokat tartalmazó vakcinák |
| MX2020003591A (es) * | 2017-10-12 | 2020-07-22 | Intervet Int Bv | Constructos del virus recombinante no patogenico de la enfermedad de marek que codifica multiples antigenos heterologos. |
| CN109136198B (zh) * | 2018-08-21 | 2021-04-13 | 华南农业大学 | 一种表达鸡传染性贫血病毒vp1、vp2基因重组鸡痘病毒活载体疫苗 |
| WO2020068631A1 (en) | 2018-09-24 | 2020-04-02 | Merck Sharp & Dohme Corp. | Expression vectors for eukaryotic expression systems |
| JP2022547975A (ja) | 2019-09-11 | 2022-11-16 | ゾエティス・サービシーズ・エルエルシー | 鳥病原体の抗原を発現する組換えシチメンチョウヘルペスウイルスベクターおよびそれらの使用 |
| US20230031097A1 (en) | 2019-12-20 | 2023-02-02 | Intervet Inc. | Multivalent hvt vector vaccine |
| KR20220160042A (ko) * | 2020-03-27 | 2022-12-05 | 스벤스카 박신파브리셴 프로둑숀 아베 | 코로나바이러스의 치료 및 예방을 위한 조성물 및 방법 |
| US12440556B2 (en) * | 2020-06-15 | 2025-10-14 | Zoetis Services Llc | Genetically modified cell line for production of Marek's disease virus vaccine and methods of making and using the same |
| EP4168043A1 (en) * | 2020-06-17 | 2023-04-26 | Boehringer Ingelheim Vetmedica GmbH | Recombinant hvt vectors expressing influenza hemagglutinin and immunogenic compositions, and production and uses thereof |
| KR102221150B1 (ko) | 2020-08-19 | 2021-02-26 | 국방과학연구소 | 이중 항원 발현벡터 및 이를 포함한 유전자 백신 |
| CN112375125B (zh) * | 2020-11-23 | 2021-09-28 | 东北农业大学 | 一种多肽及其在预防鸡传染性法氏囊病中的应用 |
| CN116648259A (zh) | 2020-12-24 | 2023-08-25 | 英特维特国际股份有限公司 | 多价hvt载体疫苗 |
| EP4518893A1 (en) | 2022-05-05 | 2025-03-12 | Intervet International B.V. | New multivalent hvt vector vaccine |
| CN116064668B (zh) * | 2022-11-10 | 2024-08-02 | 华南农业大学 | 一种重组腺病毒质粒、制备方法和重组腺病毒 |
| CN118546258B (zh) * | 2024-06-03 | 2024-11-29 | 中国动物卫生与流行病学中心 | 一种鸡传染性支气管炎病毒抗原表位融合肽及其在间接elisa检测中的应用 |
| WO2026013162A1 (en) | 2024-07-10 | 2026-01-15 | Boehringer Ingelheim Vetmedica Gmbh | Herpes virus of turkey vector based h5ha vaccine for the treatment and prevention of avian influenza infections in turkeys |
| WO2026013161A1 (en) | 2024-07-10 | 2026-01-15 | Boehringer Ingelheim Vetmedica Gmbh | Prime and boost vaccination for the treatment and prevention of avian influenza infections in avians |
| CN119265145A (zh) * | 2024-12-10 | 2025-01-07 | 中国农业科学院都市农业研究所 | 一种共同表达新城疫病毒f基因和传染性法氏囊病毒超强毒株vp2基因的重组马立克氏病病毒及其应用 |
| CN119265146B (zh) * | 2024-12-10 | 2025-08-12 | 中国农业科学院都市农业研究所 | 一种共同表达新城疫病毒f基因和传染性法氏囊病毒新型变异株vp2基因的重组马立克氏病病毒及其应用 |
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- 2017-12-13 HU HUE17823319A patent/HUE060926T2/hu unknown
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- 2017-12-13 EP EP22169088.6A patent/EP4112072A1/en active Pending
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- 2017-12-13 KR KR1020197019510A patent/KR102617503B1/ko active Active
- 2017-12-13 KR KR1020257007666A patent/KR20250040086A/ko active Pending
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- 2017-12-13 US US15/840,764 patent/US10323257B2/en active Active
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- 2017-12-13 PT PT178233193T patent/PT3554536T/pt unknown
- 2017-12-13 WO PCT/US2017/066139 patent/WO2018112051A1/en not_active Ceased
- 2017-12-13 RU RU2019121381A patent/RU2752836C2/ru active
- 2017-12-13 CN CN202311310992.3A patent/CN117357641A/zh active Pending
- 2017-12-13 EP EP20177566.5A patent/EP3744342A1/en not_active Withdrawn
- 2017-12-13 EP EP17823319.3A patent/EP3554536B1/en active Active
- 2017-12-13 PL PL17823319.3T patent/PL3554536T3/pl unknown
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2019
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- 2019-06-14 CL CL2019001640A patent/CL2019001640A1/es unknown
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- 2019-07-12 EC ECSENADI201949787A patent/ECSP19049787A/es unknown
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