AR118443A1 - Proteínas de fusión, bacterias recombinantes y fragmentos de exosporas para control de plagas y salud de las plantas - Google Patents
Proteínas de fusión, bacterias recombinantes y fragmentos de exosporas para control de plagas y salud de las plantasInfo
- Publication number
- AR118443A1 AR118443A1 ARP200100773A ARP200100773A AR118443A1 AR 118443 A1 AR118443 A1 AR 118443A1 AR P200100773 A ARP200100773 A AR P200100773A AR P200100773 A ARP200100773 A AR P200100773A AR 118443 A1 AR118443 A1 AR 118443A1
- Authority
- AR
- Argentina
- Prior art keywords
- exospore
- fusion proteins
- fragments
- exosporal
- bacillus cereus
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 4
- 241000894006 Bacteria Species 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 241000193755 Bacillus cereus Species 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 102000037865 fusion proteins Human genes 0.000 abstract 3
- 108020001507 fusion proteins Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000193747 Bacillus firmus Species 0.000 abstract 1
- 241000244206 Nematoda Species 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 102000012479 Serine Proteases Human genes 0.000 abstract 1
- 108010022999 Serine Proteases Proteins 0.000 abstract 1
- 229940005348 bacillus firmus Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/22—Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente se refiere a una proteína de fusión que tiene una secuencia dirigida, proteína de exosporas o fragmento de proteína de exosporas que dirige la proteína de fusión a las exosporas de un miembro de la familia Bacillus cereus recombinante y una enzima que tiene actividad de serina proteasa, en donde la enzima que tiene actividad de serina proteasa forma parte de Bacillus firmus o es una variante de dicha enzima. La presente también proporciona un miembro de la familia Bacillus cereus recombinante que expresa dichas proteínas de fusión y fragmentos de exosporas derivados de dicho miembro de la familia Bacillus cereus recombinante. También se proporcionan métodos de uso de dichos miembros de la familia Bacillus cereus recombinantes o fragmentos de exosporas derivados de estos para el control de nematodos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962820773P | 2019-03-19 | 2019-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR118443A1 true AR118443A1 (es) | 2021-10-06 |
Family
ID=70293065
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP200100773A AR118443A1 (es) | 2019-03-19 | 2020-03-18 | Proteínas de fusión, bacterias recombinantes y fragmentos de exosporas para control de plagas y salud de las plantas |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11793196B2 (es) |
| EP (1) | EP3941204A1 (es) |
| JP (1) | JP2022525639A (es) |
| KR (1) | KR20210142673A (es) |
| CN (1) | CN113825401A (es) |
| AR (1) | AR118443A1 (es) |
| AU (1) | AU2020241392B2 (es) |
| BR (1) | BR112021017827A2 (es) |
| CA (1) | CA3133986A1 (es) |
| CR (1) | CR20210478A (es) |
| MX (1) | MX2021011358A (es) |
| WO (1) | WO2020190993A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3684168A4 (en) | 2017-09-20 | 2021-10-27 | Spogen Biotech Inc. | FUSION PROTEINS, RECOMBINANT BACTERIA AND EXOSPORIUM FRAGMENTS FOR PLANT HEALTH |
| AU2020241392B2 (en) * | 2019-03-19 | 2025-05-01 | Bayer Cropscience Lp | Fusion proteins, recombinant bacteria, and exosporium fragments for pest control and plant health |
| AR124633A1 (es) * | 2020-09-21 | 2023-04-19 | Bayer Cropscience Lp | Nuevas serina proteasas |
| US10947552B1 (en) | 2020-09-30 | 2021-03-16 | Alpine Roads, Inc. | Recombinant fusion proteins for producing milk proteins in plants |
| US10894812B1 (en) | 2020-09-30 | 2021-01-19 | Alpine Roads, Inc. | Recombinant milk proteins |
| AU2021353004A1 (en) | 2020-09-30 | 2023-04-13 | Nobell Foods, Inc. | Recombinant milk proteins and food compositions comprising the same |
| WO2023092050A1 (en) * | 2021-11-20 | 2023-05-25 | Bayer Cropscience Lp | Beneficial combinations with recombinant bacillus cells expressing a serine protease |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9518323D0 (en) * | 1995-09-07 | 1995-11-08 | Steidler Lothar | Materials and methods relating to the attachment and display of substances on cell surfaces |
| US9133251B2 (en) * | 2008-02-22 | 2015-09-15 | The Curators Of The University Of Missouri | Bacillus based delivery system and methods of use |
| US20100112670A1 (en) * | 2008-06-25 | 2010-05-06 | Vaxiion Therapeutics, Inc. | Regulated genetic suicide mechanism compositions and methods |
| US20110269804A1 (en) * | 2008-08-22 | 2011-11-03 | Syngenta Crop Protection Llc | Insecticidal compounds |
| US20130267415A1 (en) * | 2010-12-15 | 2013-10-10 | Syngenta Participations Ag | Pesticidal mixtures |
| DE102012201297A1 (de) | 2012-01-31 | 2013-08-01 | Basf Se | Expressionsverfahren |
| EP2809145A4 (en) | 2012-02-01 | 2015-09-16 | Dow Agrosciences Llc | CHLOROPLAST TRANSIT PEPTIDES |
| US9573980B2 (en) | 2013-03-15 | 2017-02-21 | Spogen Biotech Inc. | Fusion proteins and methods for stimulating plant growth, protecting plants from pathogens, and immobilizing Bacillus spores on plant roots |
| IL315468A (en) | 2014-09-17 | 2024-11-01 | Spogen Biotech Inc | Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria |
| AR101957A1 (es) * | 2014-09-17 | 2017-01-25 | Bayer Cropscience Lp | Composiciones que comprenden células recombinantes de bacillus y un insecticida |
| US20170295798A1 (en) | 2014-09-17 | 2017-10-19 | Bayer Cropscience Lp | Compositions comprising recombinant bacillus cells and a fungicide |
| AR101960A1 (es) | 2014-09-17 | 2017-01-25 | Bayer Cropscience Lp | Composiciones que comprenden células recombinantes de bacillus y un fungicida |
| CA2961382C (en) | 2014-09-17 | 2024-02-13 | Bayer Cropscience Lp | Compositions comprising recombinant bacillus cells and another biological control agent |
| EP3193618A1 (en) | 2014-09-17 | 2017-07-26 | Bayer Cropscience LP | Compositions comprising recombinant bacillus cells and an insecticide |
| US11154064B2 (en) | 2014-09-17 | 2021-10-26 | Bayer Cropscience Lp | Compositions comprising recombinant bacillus cells and another biological control agent |
| JP6581346B2 (ja) * | 2014-11-19 | 2019-09-25 | 花王株式会社 | 精製アルカリプロテアーゼの製造方法 |
| WO2017161181A1 (en) | 2016-03-16 | 2017-09-21 | Spogen Biotech Inc. | Fusion proteins, recombinant bacteria, and exosporium fragments for animal health and aquaculture |
| EP3684168A4 (en) | 2017-09-20 | 2021-10-27 | Spogen Biotech Inc. | FUSION PROTEINS, RECOMBINANT BACTERIA AND EXOSPORIUM FRAGMENTS FOR PLANT HEALTH |
| AU2020241392B2 (en) * | 2019-03-19 | 2025-05-01 | Bayer Cropscience Lp | Fusion proteins, recombinant bacteria, and exosporium fragments for pest control and plant health |
-
2020
- 2020-03-18 AU AU2020241392A patent/AU2020241392B2/en not_active Expired - Fee Related
- 2020-03-18 CA CA3133986A patent/CA3133986A1/en active Pending
- 2020-03-18 CR CR20210478A patent/CR20210478A/es unknown
- 2020-03-18 CN CN202080034781.XA patent/CN113825401A/zh active Pending
- 2020-03-18 WO PCT/US2020/023255 patent/WO2020190993A1/en not_active Ceased
- 2020-03-18 JP JP2021556275A patent/JP2022525639A/ja active Pending
- 2020-03-18 US US16/822,279 patent/US11793196B2/en active Active
- 2020-03-18 MX MX2021011358A patent/MX2021011358A/es unknown
- 2020-03-18 AR ARP200100773A patent/AR118443A1/es unknown
- 2020-03-18 EP EP20719811.0A patent/EP3941204A1/en active Pending
- 2020-03-18 KR KR1020217033114A patent/KR20210142673A/ko not_active Ceased
- 2020-03-18 BR BR112021017827A patent/BR112021017827A2/pt unknown
-
2023
- 2023-09-05 US US18/461,008 patent/US12527323B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020190993A1 (en) | 2020-09-24 |
| EP3941204A1 (en) | 2022-01-26 |
| US20200296960A1 (en) | 2020-09-24 |
| BR112021017827A2 (pt) | 2021-11-30 |
| JP2022525639A (ja) | 2022-05-18 |
| AU2020241392B2 (en) | 2025-05-01 |
| MX2021011358A (es) | 2021-10-13 |
| US11793196B2 (en) | 2023-10-24 |
| AU2020241392A1 (en) | 2021-09-30 |
| US20240008485A1 (en) | 2024-01-11 |
| CN113825401A (zh) | 2021-12-21 |
| CA3133986A1 (en) | 2020-09-24 |
| CR20210478A (es) | 2021-11-05 |
| US12527323B2 (en) | 2026-01-20 |
| KR20210142673A (ko) | 2021-11-25 |
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