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AR102049A1 - Microorganismo que produce o-fosfoserina y un procedimiento para la producción de o-fosfoserina o l-cisteína por el uso del mismo - Google Patents

Microorganismo que produce o-fosfoserina y un procedimiento para la producción de o-fosfoserina o l-cisteína por el uso del mismo

Info

Publication number
AR102049A1
AR102049A1 ARP150102593A ARP150102593A AR102049A1 AR 102049 A1 AR102049 A1 AR 102049A1 AR P150102593 A ARP150102593 A AR P150102593A AR P150102593 A ARP150102593 A AR P150102593A AR 102049 A1 AR102049 A1 AR 102049A1
Authority
AR
Argentina
Prior art keywords
phosphoserine
microorganism
cysteine
same
phosphoserin
Prior art date
Application number
ARP150102593A
Other languages
English (en)
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of AR102049A1 publication Critical patent/AR102049A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01095—Phosphoglycerate dehydrogenase (1.1.1.95)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01065—O-Phosphoserine sulfhydrylase (2.5.1.65)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01052—Phosphoserine transaminase (2.6.1.52)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03003—Phosphoserine phosphatase (3.1.3.3)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente se refiere a un microorganismo (Escherichia coli), en el que la actividad de un polipeptido capaz de exportar O-fosfoserina (OPS) está aumentada, y un procedimiento para producir O-fosfoserina, cisteína o un derivado de cisteína usando el microorganismo. Reivindicación 9: Un procedimiento para producir cisteína o un derivado de la misma, que comprende: a) producir O-fosfoserina (OPS) por medio del cultivo del microorganismo de acuerdo con cualquiera de las reivindicaciones 1 a 4 en un medio; y b) hacer reaccionar la O-fosfoserina (OPS) producida en a) o un cultivo que contiene la misma con un sulfuro, en presencia de O-fosfoserina sulfhidrilasa (OPSS) o un microorganismo capaz de expresar la misma.
ARP150102593A 2014-08-12 2015-08-11 Microorganismo que produce o-fosfoserina y un procedimiento para la producción de o-fosfoserina o l-cisteína por el uso del mismo AR102049A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020140104670A KR101677328B1 (ko) 2014-08-12 2014-08-12 O-포스포세린 생산 미생물 및 이를 이용한 o-포스포세린 또는 l-시스테인 생산 방법

Publications (1)

Publication Number Publication Date
AR102049A1 true AR102049A1 (es) 2017-02-01

Family

ID=55304343

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150102593A AR102049A1 (es) 2014-08-12 2015-08-11 Microorganismo que produce o-fosfoserina y un procedimiento para la producción de o-fosfoserina o l-cisteína por el uso del mismo

Country Status (11)

Country Link
US (1) US10323262B2 (es)
EP (1) EP3181685B1 (es)
JP (2) JP6570617B2 (es)
KR (1) KR101677328B1 (es)
CN (1) CN106795485B (es)
AR (1) AR102049A1 (es)
ES (1) ES2753413T3 (es)
RU (1) RU2663726C1 (es)
TW (1) TWI654305B (es)
UA (1) UA119985C2 (es)
WO (1) WO2016024771A1 (es)

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KR101694632B1 (ko) * 2015-09-11 2017-01-10 씨제이제일제당 (주) 신규 ｏ-포스포세린 배출 단백질 변이체 및 이를 이용한 ｏ-포스포세린, 시스테인 및 이의 유도체의 생산방법
JP2018023356A (ja) * 2016-08-04 2018-02-15 三洋化成工業株式会社 有用物質の生産方法
KR101825310B1 (ko) * 2016-12-29 2018-03-15 씨제이제일제당 (주) O-포스포세린을 생산하는 에스케리키아 속 미생물 및 이를 이용한 o-포스포세린 또는 l-시스테인을 생산하는 방법
BR112022013303A2 (pt) * 2020-06-09 2022-12-20 Cj Cheiljedang Corp Polipeptídeo com atividade de exportação de o-fosfoserina (ops), micro-organismo produtor de o-fosfoserina, métodos e usos
FR3112549A1 (fr) * 2020-07-20 2022-01-21 Arkema France Procede ameliore de synthese de mercaptans fonctionnalises
KR102414743B1 (ko) * 2020-09-09 2022-06-29 씨제이제일제당 주식회사 신규 o-포스포세린 배출 단백질 및 이를 이용한 o-포스포세린, 시스테인 및 이의 유도체의 생산 방법
FR3117115B1 (fr) * 2020-12-04 2023-05-05 Arkema France Procede de synthese de mercaptans fonctionnalises sous pression d’h2s
CN118813659A (zh) * 2021-04-14 2024-10-22 上海凯赛生物技术股份有限公司 用于发酵生产1,5-戊二胺的重组dna、菌株及其用途
KR102756052B1 (ko) * 2021-06-03 2025-01-21 씨제이제일제당 주식회사 신규한 YhhS 변이체 및 이를 이용한 O-포스포세린, 시스테인 및 이의 유도체의 생산방법
KR102707457B1 (ko) * 2021-06-11 2024-09-20 씨제이제일제당 주식회사 신규한 MdtH 변이체 및 이를 이용한 O-포스포세린, 시스테인 및 이의 유도체의 생산방법
KR102654301B1 (ko) * 2021-06-23 2024-04-04 씨제이제일제당 주식회사 NADH:quinone 산화환원효소의 발현이 조절된 재조합 미생물 및 이를 이용한 O-포스포세린, 시스테인 및 이의 유도체의 생산방법
KR102688937B1 (ko) * 2021-12-31 2024-07-29 씨제이제일제당 주식회사 O-포스포세린 생산 미생물 및 이를 이용한 o-포스포세린 또는 l-시스테인 생산 방법
CN118922530A (zh) 2022-03-23 2024-11-08 东丽株式会社 用于生产3-羟基己二酸和/或3-氧代己二酸的基因修饰微生物以及该化学品的制造方法
KR20240147887A (ko) 2023-03-31 2024-10-10 씨제이제일제당 (주) 망간 유입 단백질의 활성이 조절된 재조합 미생물 및 이를 이용한 o-포스포세린, 시스테인 및 이의 유도체의 생산방법
KR20240147868A (ko) 2023-03-31 2024-10-10 씨제이제일제당 (주) 알킬하이드로퍼옥사이드 환원효소의 발현이 조절된 재조합 미생물 및 이를 이용한 o-포스포세린, 시스테인 및 이의 유도체의 생산방법
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Also Published As

Publication number Publication date
US10323262B2 (en) 2019-06-18
EP3181685A1 (en) 2017-06-21
US20170260556A1 (en) 2017-09-14
JP2019150038A (ja) 2019-09-12
EP3181685B1 (en) 2019-08-14
JP6570617B2 (ja) 2019-09-04
JP2017528126A (ja) 2017-09-28
KR20160020050A (ko) 2016-02-23
CN106795485A (zh) 2017-05-31
CN106795485B (zh) 2020-10-30
JP6807976B2 (ja) 2021-01-06
EP3181685A4 (en) 2017-12-27
TWI654305B (zh) 2019-03-21
ES2753413T3 (es) 2020-04-08
TW201612319A (en) 2016-04-01
UA119985C2 (uk) 2019-09-10
WO2016024771A1 (ko) 2016-02-18
KR101677328B1 (ko) 2016-11-18
RU2663726C1 (ru) 2018-08-08

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