MX2017015668A - Microorganismos recombinante para la produccion mejorada de quimicos finos. - Google Patents
Microorganismos recombinante para la produccion mejorada de quimicos finos.Info
- Publication number
- MX2017015668A MX2017015668A MX2017015668A MX2017015668A MX2017015668A MX 2017015668 A MX2017015668 A MX 2017015668A MX 2017015668 A MX2017015668 A MX 2017015668A MX 2017015668 A MX2017015668 A MX 2017015668A MX 2017015668 A MX2017015668 A MX 2017015668A
- Authority
- MX
- Mexico
- Prior art keywords
- improved production
- fine chemicals
- recombinant microorganisms
- recombinant
- nucleic acid
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title abstract 3
- 239000012847 fine chemical Substances 0.000 title 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 2
- 235000004279 alanine Nutrition 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a una molécula de ácido nucleico recombinante, un microorganismo recombinante, a un método para producir alanina y al uso de la molécula de ácido nucleico recombinante o el microorganismo recombinante para la producción de alanina por fermentación.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562171036P | 2015-06-04 | 2015-06-04 | |
| PCT/EP2016/062457 WO2016193351A2 (en) | 2015-06-04 | 2016-06-02 | Recombinant microorganism for improved production of fine chemicals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017015668A true MX2017015668A (es) | 2018-08-15 |
| MX389370B MX389370B (es) | 2025-03-20 |
Family
ID=56119472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017015668A MX389370B (es) | 2015-06-04 | 2016-06-02 | Microorganismo recombinante para la produccion mejorada de quimicos finos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10519474B2 (es) |
| EP (1) | EP3303372A2 (es) |
| JP (1) | JP7071124B2 (es) |
| KR (1) | KR20180011313A (es) |
| CN (1) | CN108350040B (es) |
| BR (1) | BR112017025923A2 (es) |
| CA (1) | CA2988415A1 (es) |
| MX (1) | MX389370B (es) |
| PH (1) | PH12017502215A1 (es) |
| RU (1) | RU2017146342A (es) |
| WO (1) | WO2016193351A2 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
| MX347962B (es) | 2003-08-01 | 2017-05-19 | Basf Plant Science Gmbh * | Metodo para la produccion de acidos grasos poli-insaturados en organismos transgenicos. |
| AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
| JP7071124B2 (ja) | 2015-06-04 | 2022-05-18 | ビーエーエスエフ ソシエタス・ヨーロピア | ファインケミカルの生産改善のための組換え微生物 |
| RU2018100807A (ru) | 2015-06-12 | 2019-07-12 | Басф Се | Рекомбинантный микроорганизм для улучшенного получения аланина |
| BR112018009729A8 (pt) | 2015-12-02 | 2019-02-26 | Basf Se | método para produzir um polipeptídeo recombinante, fungo filamentoso myceliophthora thermophila e uso de uma construção de ácido nucleico |
| MX378193B (es) | 2015-12-02 | 2025-03-04 | Basf Se | Metodo para producir proteinas en hongos filamentosos con accion clr1 reducida. |
| AU2018267693B2 (en) * | 2017-05-17 | 2024-07-18 | Microbio Pty Ltd | Biomarkers and uses thereof |
| CN108660142A (zh) * | 2018-05-28 | 2018-10-16 | 河北大学 | 一种高产l-丙氨酸的基因及其工程菌的构建方法 |
| KR102306010B1 (ko) | 2021-04-07 | 2021-09-27 | 씨제이제일제당 (주) | 신규한 분지쇄아미노산 투과효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| CN115960942A (zh) * | 2021-10-08 | 2023-04-14 | 安徽丰原生物技术股份有限公司 | 一种生产l-丙氨酸的基因工程菌株及其构建方法和应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3853683T2 (de) | 1987-10-07 | 1995-08-31 | Univ Washington | Verfahren zur erhaltung eines erwünschten rekombinanten gens in einer genetischen zellpopulation. |
| US5019509A (en) | 1988-04-20 | 1991-05-28 | Genetics Institute, Inc. | Method and compositions for the production of l-alanine and derivatives thereof |
| DE4319935A1 (de) | 1993-06-16 | 1994-12-22 | Basf Ag | Verwendung von Glycin-N,N-diessigsäure-Derivaten als Komplexbildner für Erdalkali- und Schwermetallionen |
| DE733059T1 (de) | 1993-12-09 | 1997-08-28 | Univ Jefferson | Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen |
| US6555732B1 (en) | 1998-09-14 | 2003-04-29 | Pioneer Hi-Bred International, Inc. | Rac-like genes and methods of use |
| RU2268305C2 (ru) | 2003-12-18 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) | Способ получения l-аминокислот с использованием бактерий с оптимизированным уровнем генной экспрессии |
| DE102004003411A1 (de) | 2004-01-23 | 2005-09-01 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| JP4836440B2 (ja) | 2004-03-10 | 2011-12-14 | センター・フォー・ディーエヌエイ・フィンガープリンティング・アンド・ダイアグノスティックス | 微生物を用いたアルギニン産生の方法 |
| WO2007120198A2 (en) | 2005-11-08 | 2007-10-25 | University Of Florida Research Foundation, Inc. | Materials and methods for improved microbial production of organic compounds |
| EP2055771A3 (en) * | 2006-03-23 | 2009-07-08 | Ajinomoto Co., Inc. | A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA |
| JP2010110217A (ja) | 2007-02-22 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造法 |
| WO2008119009A2 (en) * | 2007-03-27 | 2008-10-02 | University Of Florida Research Foundation, Inc. | Materials and methods for efficient alanine production |
| EP2152883A4 (en) | 2007-05-10 | 2010-10-27 | Univ Arizona | RECOMBINANT BACTERIA WITH VECTORS FOR THE EXPRESSION OF NUCLEIC ACID SEQUENCES-CODING ANTIGENES |
| RU2392322C2 (ru) | 2007-08-14 | 2010-06-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ L-ТРЕОНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН yahN |
| RU2007147436A (ru) * | 2007-12-21 | 2009-06-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Бактерия-продуцент (2s,3r,4s)-4-гидрокси-l-изолейцина и способ продукции (2s,3r,4s)-4-гидрокси-l-изолейцина |
| US7915011B2 (en) | 2009-03-05 | 2011-03-29 | E.I. Du Pont De Nemours And Company | Host cell modifications that improve peptide production and downstream processing |
| ES2660773T5 (es) | 2011-05-03 | 2021-11-25 | Basf Se | Procedimiento para la preparación de una sal cristalina trialcalino-metálica de L-MGDA |
| JP2013000064A (ja) | 2011-06-17 | 2013-01-07 | Tohoku Univ | 組換え微生物、当該組換え微生物を用いたアラニンの製造方法 |
| KR102093172B1 (ko) | 2012-07-11 | 2020-03-25 | 아디쎄오 프랑스 에스에이에스 | 2,4-다이하이드록시부티레이트의 제조 방법 |
| RU2016111682A (ru) | 2013-08-30 | 2017-10-05 | Басф Се | Модифицированный микроорганизм для улучшенного получения аланина |
| KR102400332B1 (ko) | 2013-09-25 | 2022-05-20 | 바스프 에스이 | 정제 화학약품의 개선된 생산을 위한 재조합 미생물 |
| CN105899664B (zh) * | 2013-12-13 | 2021-08-31 | 巴斯夫欧洲公司 | 用于精细化学品的改进生产的重组微生物 |
| CN106661595A (zh) | 2014-03-19 | 2017-05-10 | 巴斯夫欧洲公司 | 在发酵中使用甘油和限制进料的碳水化合物 |
| US10758157B2 (en) | 2014-10-24 | 2020-09-01 | Koninklijke Philips N.V. | Determining if airway clearance is required during respiratory therapy |
| JP7071124B2 (ja) | 2015-06-04 | 2022-05-18 | ビーエーエスエフ ソシエタス・ヨーロピア | ファインケミカルの生産改善のための組換え微生物 |
| RU2018100807A (ru) | 2015-06-12 | 2019-07-12 | Басф Се | Рекомбинантный микроорганизм для улучшенного получения аланина |
-
2016
- 2016-06-02 JP JP2017562747A patent/JP7071124B2/ja not_active Expired - Fee Related
- 2016-06-02 MX MX2017015668A patent/MX389370B/es unknown
- 2016-06-02 CA CA2988415A patent/CA2988415A1/en active Pending
- 2016-06-02 BR BR112017025923A patent/BR112017025923A2/pt not_active Application Discontinuation
- 2016-06-02 EP EP16728651.7A patent/EP3303372A2/en not_active Withdrawn
- 2016-06-02 US US15/579,291 patent/US10519474B2/en not_active Expired - Fee Related
- 2016-06-02 WO PCT/EP2016/062457 patent/WO2016193351A2/en not_active Ceased
- 2016-06-02 KR KR1020187000090A patent/KR20180011313A/ko not_active Withdrawn
- 2016-06-02 RU RU2017146342A patent/RU2017146342A/ru not_active Application Discontinuation
- 2016-06-02 CN CN201680035843.2A patent/CN108350040B/zh not_active Expired - Fee Related
-
2017
- 2017-12-04 PH PH12017502215A patent/PH12017502215A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX389370B (es) | 2025-03-20 |
| WO2016193351A2 (en) | 2016-12-08 |
| JP7071124B2 (ja) | 2022-05-18 |
| US10519474B2 (en) | 2019-12-31 |
| CN108350040B (zh) | 2022-03-25 |
| RU2017146342A (ru) | 2019-07-10 |
| PH12017502215A1 (en) | 2018-07-02 |
| EP3303372A2 (en) | 2018-04-11 |
| US20180148748A1 (en) | 2018-05-31 |
| WO2016193351A3 (en) | 2017-01-12 |
| CN108350040A (zh) | 2018-07-31 |
| BR112017025923A2 (pt) | 2018-08-14 |
| RU2017146342A3 (es) | 2020-07-17 |
| CA2988415A1 (en) | 2016-12-08 |
| KR20180011313A (ko) | 2018-01-31 |
| JP2018517413A (ja) | 2018-07-05 |
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