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AR101434A1 - Método para producir (r)-1,1,3-trimetil-4-aminoindano - Google Patents

Método para producir (r)-1,1,3-trimetil-4-aminoindano

Info

Publication number
AR101434A1
AR101434A1 ARP150100281A ARP150100281A AR101434A1 AR 101434 A1 AR101434 A1 AR 101434A1 AR P150100281 A ARP150100281 A AR P150100281A AR P150100281 A ARP150100281 A AR P150100281A AR 101434 A1 AR101434 A1 AR 101434A1
Authority
AR
Argentina
Prior art keywords
trimethyl
aminoindane
producing
aminoindano
trimetil
Prior art date
Application number
ARP150100281A
Other languages
English (en)
Inventor
Tanimoto Masaya
Inui Tomohiko
Takahashi Tomoaki
Hiraguru Natsuru
Matsunaga Tadafumi
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of AR101434A1 publication Critical patent/AR101434A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/84—Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/86—Separation
    • C07C209/88—Separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/90—Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C07C211/60—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton containing a ring other than a six-membered aromatic ring forming part of at least one of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

Se ha demandado un método de producción para obtener (R)-1,1,3-trimetil-4-aminoindano en un alto rendimiento. El método para producir (R)-1,1,3-trimetil-4-aminoindano incluye las siguientes etapas (A), (B) y (C): (A): una etapa de resolución óptica 1,1,3-trimetil-4-aminoindano para obtener (R)-1,1,3-trimetil-4-aminoindano y (S)-1,1,3-trimetil-4-aminoindano; (B): una etapa de racemización del (S)-1,1,3-trimetil-4-aminoindano obtenido en la etapa (A) o (C) para obtener 1,1,3-trimetil-4-aminoindano; y (C): una etapa de resolución óptica el 1,1,3-trimetil-4-aminoindano obtenido en la etapa (B) para obtener (R)-1,1,3-trimetil-4-aminoindano y (S)-1,1,3-trimetil-4-aminoindano.
ARP150100281A 2014-02-07 2015-01-30 Método para producir (r)-1,1,3-trimetil-4-aminoindano AR101434A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014021976 2014-02-07

Publications (1)

Publication Number Publication Date
AR101434A1 true AR101434A1 (es) 2016-12-21

Family

ID=53777608

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150100281A AR101434A1 (es) 2014-02-07 2015-01-30 Método para producir (r)-1,1,3-trimetil-4-aminoindano

Country Status (14)

Country Link
US (1) US9765032B2 (es)
EP (1) EP3103789B1 (es)
JP (1) JP6451652B2 (es)
KR (1) KR102264639B1 (es)
CN (1) CN105992755B (es)
AR (1) AR101434A1 (es)
AU (1) AU2014381760B2 (es)
BR (1) BR112016017648B1 (es)
DK (1) DK3103789T3 (es)
ES (1) ES2702891T3 (es)
IL (1) IL246923B (es)
RU (1) RU2016135762A (es)
TW (1) TWI646071B (es)
WO (1) WO2015118793A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ706723A (en) 2012-10-12 2018-07-27 Exelixis Inc Novel process for making compounds for use in the treatment of cancer
JP7220151B2 (ja) * 2017-08-28 2023-02-09 株式会社日本ファインケム ピラゾール－４－カルボキサミド誘導体の製造方法
JP7317037B2 (ja) 2018-03-26 2023-07-28 バイエル・アクチエンゲゼルシヤフト キラルイリジウム触媒の存在下での４－置換１，２－ジヒドロキノリンのエナンチオ選択的水素化
US12410138B2 (en) 2019-09-25 2025-09-09 Bayer Aktiengesellschaft Process comprising the use of new iridium catalysts for enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines
KR102898694B1 (ko) 2019-09-25 2025-12-10 바이엘 악티엔게젤샤프트 키랄 이리듐 촉매 및 첨가제의 존재 하의 4-치환된 1,2-디히드로퀴놀린의 개선된 거울상이성질체선택적 수소첨가
IT201900017330A1 (it) * 2019-09-26 2021-03-26 Isagro Spa Processo per la preparazione di (r)-4-amminoindani e corrispondenti ammidi.
IL292513B2 (en) * 2019-11-01 2025-11-01 Sumitomo Chemical Co Crystal of 3-(difluoromethyl)-1-methyl-n-(1,1,3-trimethyl-2,3-dihydro-1h-inden-4-yl)-1h-pyrazole-4-carboxamide
JP2023120459A (ja) * 2020-07-17 2023-08-30 住友化学株式会社 光学活性な１，１，３－トリメチル－４－アミノインダンの製造方法
KR20230041010A (ko) 2020-07-17 2023-03-23 스미또모 가가꾸 가부시끼가이샤 광학 활성인 화합물의 제조 방법
CN114773263B (zh) * 2022-05-16 2023-09-05 江苏百康德医药科技有限公司 (r)-2,2,4-三甲基-1,2,3,4-四氢喹啉的制备方法
CN116396189B (zh) * 2023-04-06 2024-11-05 无锡科华生物科技有限公司 一种(s)-(+)-1-茚满基异氰酸酯的制备方法

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US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
US5521317A (en) * 1993-10-22 1996-05-28 American Cyanamid Co. Processes for the preparation of pesticides and intermediates
JP3892503B2 (ja) * 1996-09-02 2007-03-14 長瀬産業株式会社 接触還元触媒を用いる光学活性アミンのラセミ化法
JP4834333B2 (ja) 2005-06-27 2011-12-14 アルプス薬品工業株式会社 光学活性ベンジルアミン誘導体の製造方法
JP2011012032A (ja) 2009-07-03 2011-01-20 Yamakawa Yakuhin Kogyo Kk 光学活性な３−アミノピペリジンの製造方法および製造の中間体
JP2012025735A (ja) 2010-06-24 2012-02-09 Sumitomo Chemical Co Ltd 植物病害防除組成物及び植物病害防除方法
JP6106976B2 (ja) * 2012-07-20 2017-04-05 住友化学株式会社 植物病害防除組成物およびその用途
CN104619681A (zh) * 2012-08-31 2015-05-13 住友化学株式会社 (r)-1,1,3-三甲基-4-氨基茚满的制造方法
JP6269499B2 (ja) * 2012-11-02 2018-01-31 住友化学株式会社 化合物のラセミ体の製造方法
WO2014103812A1 (ja) 2012-12-25 2014-07-03 住友化学株式会社 ピラゾール化合物の結晶の製造方法
CN105408302B (zh) 2012-12-27 2017-06-13 住友化学株式会社 制备纯化形式的胺化合物的方法

Also Published As

Publication number Publication date
BR112016017648B1 (pt) 2021-01-19
JPWO2015118793A1 (ja) 2017-03-23
AU2014381760A1 (en) 2016-08-18
TW201612153A (en) 2016-04-01
EP3103789A1 (en) 2016-12-14
AU2014381760B2 (en) 2018-08-02
TWI646071B (zh) 2019-01-01
EP3103789B1 (en) 2018-10-31
IL246923B (en) 2020-08-31
KR20160118256A (ko) 2016-10-11
RU2016135762A3 (es) 2018-08-01
EP3103789A4 (en) 2017-07-05
CN105992755B (zh) 2018-07-13
JP6451652B2 (ja) 2019-01-16
US20170166532A1 (en) 2017-06-15
DK3103789T3 (en) 2019-01-28
RU2016135762A (ru) 2018-03-14
IL246923A0 (en) 2016-09-29
WO2015118793A1 (ja) 2015-08-13
ES2702891T3 (es) 2019-03-06
CN105992755A (zh) 2016-10-05
US9765032B2 (en) 2017-09-19
KR102264639B1 (ko) 2021-06-11

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