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AR107967A1 - Ácido hialurónico modificado, método para su preparación y usos del mismo - Google Patents

Ácido hialurónico modificado, método para su preparación y usos del mismo

Info

Publication number
AR107967A1
AR107967A1 ARP170100730A ARP170100730A AR107967A1 AR 107967 A1 AR107967 A1 AR 107967A1 AR P170100730 A ARP170100730 A AR P170100730A AR P170100730 A ARP170100730 A AR P170100730A AR 107967 A1 AR107967 A1 AR 107967A1
Authority
AR
Argentina
Prior art keywords
preparation
hyaluronic acid
same
hydrogel
modified hyaluronic
Prior art date
Application number
ARP170100730A
Other languages
English (en)
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of AR107967A1 publication Critical patent/AR107967A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075Macromolecular gels
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente se relaciona, en general, con un ácido hialurónico modificado (HA) y con un método para su preparación, más específicamente con un derivado HA modificado con (poli)glicerol preparado mediante el injerto de glicidol en HA. La presente también se relaciona con el uso del derivado de HA para la preparación de una composición de relleno dérmico, un hidrogel que comprende HA entrecruzado y el derivado de HA modificado con (poli)glicerol, y un método para la preparación de dicho hidrogel. Además, la presente se relaciona con el uso del hidrogel como producto cosmético y/o estético, en particular como relleno dérmico para relleno, reemplazo y/o aumento de tejidos.
ARP170100730A 2016-03-24 2017-03-23 Ácido hialurónico modificado, método para su preparación y usos del mismo AR107967A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16000715 2016-03-24

Publications (1)

Publication Number Publication Date
AR107967A1 true AR107967A1 (es) 2018-07-04

Family

ID=55642206

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170100730A AR107967A1 (es) 2016-03-24 2017-03-23 Ácido hialurónico modificado, método para su preparación y usos del mismo

Country Status (16)

Country Link
US (1) US10640578B2 (es)
EP (1) EP3433284A1 (es)
JP (1) JP6946323B2 (es)
KR (1) KR102316644B1 (es)
CN (1) CN108779185B (es)
AR (1) AR107967A1 (es)
AU (1) AU2017237457B2 (es)
BR (1) BR112018068559B8 (es)
CA (1) CA3016272A1 (es)
IL (1) IL261574B2 (es)
MX (1) MX2018011053A (es)
RU (1) RU2733444C2 (es)
SG (1) SG11201807185UA (es)
TW (1) TWI727014B (es)
WO (1) WO2017162676A1 (es)
ZA (1) ZA201805424B (es)

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JP7501908B2 (ja) 2017-09-19 2024-06-18 香港科技大学 生体適合性材料、並びにそれを作製及び使用する方法
EP3765103A1 (en) 2018-03-12 2021-01-20 Merz Pharma GmbH & Co. KGaA Porous biomaterials for tissue regeneration
JP2022512363A (ja) * 2018-12-19 2022-02-03 メルツ ファルマ ゲーエムベーハー ウント コンパニー カーゲーアーアー アルデヒド変性ヒアルロン酸、それを調製するための方法およびその用途
IL284082B2 (en) 2018-12-19 2025-07-01 Evolved By Nature Inc Silk-hyaluronic acid tissue fillers and methods for their preparation and use
RS67193B1 (sr) * 2018-12-20 2025-10-31 Lg Chemical Ltd Filer sa odličnim svojstvima filera koji obuhvata hidrogel hijaluronske kiseline
JP7784138B2 (ja) * 2019-10-01 2025-12-11 バイオポリメリ エス.アール.エル. 超分岐ポリグリセロールポリグリシジルエーテルおよび多糖用の架橋物質としてのその使用
FR3111903B1 (fr) 2020-06-24 2022-12-02 Lab Vivacy Procede d’incorporation de composes organiques en solution au sein d’un hydrogel
FR3113522B1 (fr) 2020-08-20 2025-04-18 Lab Vivacy procédé d’évaluation des caractéristiques rhéologiques d’un gel
AU2022205343B2 (en) * 2021-01-07 2024-11-14 Lg Chem, Ltd. Crosslinked hyaluronic acid hydrogel crosslinked using crosslinker and polyol, and filler comprising same
TWI880094B (zh) 2021-06-23 2025-04-11 德商莫茲製藥有限兩合公司 以絲蛋白交聯多醣及所得材料之用途
US20230255863A1 (en) * 2021-07-29 2023-08-17 Innomed Technologies, Inc. Formulations containing erythritol and combination skin therapies
US20250340675A1 (en) 2022-01-11 2025-11-06 WiQo S.P.A. New hyaluronic acid derivatives as innovative fillers
US20250075009A1 (en) * 2022-01-14 2025-03-06 Jenkem Technology Co., Ltd. (Tianjin) Hyaluronic acid derivative or salt thereof, and preparation method therefor and application thereof
ES2947097A1 (es) * 2022-02-01 2023-08-01 Martinez Miguel Angel Gomariz Metodo cosmetico de rejuvenecimiento de la piel
FR3135399B1 (fr) 2022-03-30 2025-03-28 Lab Vivacy émulsion comprenant un hydrogel et de la graisse ou un dérivé de graisse
AU2023392523A1 (en) 2022-12-15 2025-04-10 Merz Pharma Gmbh & Co. Kgaa Injectable gel comprising botulinum toxin and uses thereof
FR3162003A1 (fr) 2024-05-12 2025-11-14 Laboratoires Vivacy Composition de biomateriau comprenant un polyhydroxybutyrate sous forme particulaire
CN120678721B (zh) * 2025-08-26 2025-10-21 平阳县人民医院 一种创面抗菌消毒凝胶及其制备方法

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Also Published As

Publication number Publication date
IL261574B2 (en) 2024-03-01
EP3433284A1 (en) 2019-01-30
BR112018068559A2 (pt) 2019-04-16
IL261574B1 (en) 2023-11-01
IL261574A (en) 2018-10-31
TWI727014B (zh) 2021-05-11
CN108779185A (zh) 2018-11-09
RU2733444C2 (ru) 2020-10-01
JP2019509385A (ja) 2019-04-04
CA3016272A1 (en) 2017-09-28
US10640578B2 (en) 2020-05-05
JP6946323B2 (ja) 2021-10-06
BR112018068559B8 (pt) 2022-11-01
US20190100605A1 (en) 2019-04-04
ZA201805424B (en) 2019-04-24
KR20180127983A (ko) 2018-11-30
MX2018011053A (es) 2019-03-28
RU2018129659A3 (es) 2020-05-27
AU2017237457A1 (en) 2018-09-06
RU2018129659A (ru) 2020-04-24
TW201805008A (zh) 2018-02-16
AU2017237457B2 (en) 2021-04-08
KR102316644B1 (ko) 2021-10-26
SG11201807185UA (en) 2018-09-27
CN108779185B (zh) 2021-09-17
WO2017162676A1 (en) 2017-09-28
BR112018068559B1 (pt) 2022-09-20

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