AR097916A1 - Elementos reguladores de tipo metalotioneína de zea mays y sus usos - Google Patents
Elementos reguladores de tipo metalotioneína de zea mays y sus usosInfo
- Publication number
- AR097916A1 AR097916A1 ARP140103695A ARP140103695A AR097916A1 AR 097916 A1 AR097916 A1 AR 097916A1 AR P140103695 A ARP140103695 A AR P140103695A AR P140103695 A ARP140103695 A AR P140103695A AR 097916 A1 AR097916 A1 AR 097916A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- sequence
- sequence identity
- transgene
- plant
- Prior art date
Links
- 230000001105 regulatory effect Effects 0.000 title 1
- 241000196324 Embryophyta Species 0.000 abstract 3
- 108700019146 Transgenes Proteins 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 235000007319 Avena orientalis Nutrition 0.000 abstract 1
- 244000075850 Avena orientalis Species 0.000 abstract 1
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 abstract 1
- 235000006008 Brassica napus var napus Nutrition 0.000 abstract 1
- 240000000385 Brassica napus var. napus Species 0.000 abstract 1
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 abstract 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 abstract 1
- 229920000742 Cotton Polymers 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 241000219146 Gossypium Species 0.000 abstract 1
- 244000020551 Helianthus annuus Species 0.000 abstract 1
- 235000003222 Helianthus annuus Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- 240000000111 Saccharum officinarum Species 0.000 abstract 1
- 235000007201 Saccharum officinarum Nutrition 0.000 abstract 1
- 241000209056 Secale Species 0.000 abstract 1
- 235000007238 Secale cereale Nutrition 0.000 abstract 1
- 240000006394 Sorghum bicolor Species 0.000 abstract 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 abstract 1
- 235000021307 Triticum Nutrition 0.000 abstract 1
- 244000098338 Triticum aestivum Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
- C12N15/8223—Vegetative tissue-specific promoters
- C12N15/8227—Root-specific
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/14—Asteraceae or Compositae, e.g. safflower, sunflower, artichoke or lettuce
- A01H6/1464—Helianthus annuus [sunflower]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
- A01H6/463—Lolium [ryegrass]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
- A01H6/4636—Oryza sp. [rice]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
- A01H6/4666—Sorghum, e.g. sudangrass
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
- A01H6/4678—Triticum sp. [wheat]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/54—Leguminosae or Fabaceae, e.g. soybean, alfalfa or peanut
- A01H6/542—Glycine max [soybean]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/60—Malvaceae, e.g. cotton or hibiscus
- A01H6/604—Gossypium [cotton]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Physiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
Reivindicación 1: Un vector de ácido nucleico que comprende un promotor ligado operativamente a i) una secuencia poliligadora; ii) un transgén o iii) una combinación de i) y ii), en donde dicho promotor comprende SEQ ID Nº 1, una secuencia que tiene 90% de identidad de secuencia con SEQ ID Nº 1, SEQ ID Nº 2, o una secuencia que tiene 90% de identidad de secuencia con SEQ ID Nº 2. Reivindicación 9: El vector de ácido nucleico de acuerdo con la reivindicación 8, en donde el transgén codifica un marcador seleccionable o un producto génico que confiere resistencia insecticida, tolerancia a herbicidas, eficacia del uso de nitrógeno, eficacia del uso de agua o calidad nutricional. Reivindicación 15: Una planta que comprende una secuencia promotora que comprende SEQ ID Nº 1, una secuencia que tiene 90% de identidad de secuencia con SEQ ID Nº 1, SEQ ID Nº 2, o una secuencia que tiene 90% de identidad de secuencia con SEQ ID Nº 2 operativamente ligada a un transgén. Reivindicación 16: La planta de acuerdo con la reivindicación 15, en donde dicha planta está seleccionada del grupo que consiste en maíz, trigo, arroz, sorgo, avena, centeno, banana, caña de azúcar, soja, algodón, girasol, y canola.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361886943P | 2013-10-04 | 2013-10-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR097916A1 true AR097916A1 (es) | 2016-04-20 |
Family
ID=52778090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140103695A AR097916A1 (es) | 2013-10-04 | 2014-10-03 | Elementos reguladores de tipo metalotioneína de zea mays y sus usos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9777286B2 (es) |
| EP (1) | EP3052633B1 (es) |
| JP (1) | JP2016536978A (es) |
| KR (1) | KR20160065952A (es) |
| CN (1) | CN105793427A (es) |
| AP (1) | AP2016009164A0 (es) |
| AR (1) | AR097916A1 (es) |
| AU (1) | AU2014329590B2 (es) |
| BR (1) | BR102014024813A2 (es) |
| CA (1) | CA2926197A1 (es) |
| IL (1) | IL244866A0 (es) |
| RU (1) | RU2016116914A (es) |
| UY (1) | UY35773A (es) |
| WO (1) | WO2015051075A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3283632A1 (en) * | 2015-04-15 | 2018-02-21 | Dow Agrosciences LLC | Plant promoter for transgene expression |
| RU2017137599A (ru) | 2015-04-15 | 2019-05-15 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Растительный промотор для экспрессии трансгена |
| US10400245B2 (en) | 2016-05-02 | 2019-09-03 | Dow Agrosciences Llc | Plant promoter and 3'UTR for transgene expression |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5380831A (en) | 1986-04-04 | 1995-01-10 | Mycogen Plant Science, Inc. | Synthetic insecticidal crystal protein gene |
| US6114138A (en) | 1984-06-04 | 2000-09-05 | Mycogen Plant Science, Inc. | Insecticidal protein fragments |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5750871A (en) | 1986-05-29 | 1998-05-12 | Calgene, Inc. | Transformation and foreign gene expression in Brassica species |
| US5004863B2 (en) | 1986-12-03 | 2000-10-17 | Agracetus | Genetic engineering of cotton plants and lines |
| EP0270496B1 (de) | 1986-12-05 | 1993-03-17 | Ciba-Geigy Ag | Verbessertes Verfahren zur Transformation von pflanzlichen Protoplasten |
| US5015580A (en) | 1987-07-29 | 1991-05-14 | Agracetus | Particle-mediated transformation of soybean plants and lines |
| US5244802A (en) | 1987-11-18 | 1993-09-14 | Phytogen | Regeneration of cotton |
| US5416011A (en) | 1988-07-22 | 1995-05-16 | Monsanto Company | Method for soybean transformation and regeneration |
| US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
| US5188960A (en) | 1989-06-27 | 1993-02-23 | Mycogen Corporation | Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins |
| US7705215B1 (en) | 1990-04-17 | 2010-04-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5550318A (en) | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
| JP3209744B2 (ja) | 1990-01-22 | 2001-09-17 | デカルブ・ジェネティクス・コーポレーション | 結実能力のある遺伝子変換コーン |
| US6403865B1 (en) | 1990-08-24 | 2002-06-11 | Syngenta Investment Corp. | Method of producing transgenic maize using direct transformation of commercially important genotypes |
| US5384253A (en) | 1990-12-28 | 1995-01-24 | Dekalb Genetics Corporation | Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes |
| US7060876B2 (en) | 1992-07-07 | 2006-06-13 | Japan Tobacco Inc. | Method for transforming monocotyledons |
| WO1994000977A1 (fr) | 1992-07-07 | 1994-01-20 | Japan Tobacco Inc. | Procede de transformation d'une monocotyledone |
| CA2148499C (en) | 1993-09-03 | 2006-07-11 | Hideaki Saito | Method for transforming monocotyledons using scutella of immature embryos |
| US5635055A (en) | 1994-07-19 | 1997-06-03 | Exxon Research & Engineering Company | Membrane process for increasing conversion of catalytic cracking or thermal cracking units (law011) |
| US5846797A (en) | 1995-10-04 | 1998-12-08 | Calgene, Inc. | Cotton transformation |
| AU708256B2 (en) | 1995-10-13 | 1999-07-29 | Dow Agrosciences Llc | Modified bacillus thuringiensis gene for lepidopteran control in plants |
| US6083499A (en) | 1996-04-19 | 2000-07-04 | Mycogen Corporation | Pesticidal toxins |
| US5981840A (en) | 1997-01-24 | 1999-11-09 | Pioneer Hi-Bred International, Inc. | Methods for agrobacterium-mediated transformation |
| KR20010073216A (ko) | 1998-10-23 | 2001-07-31 | 칼튼 제이. 에이블 | 약 15kDa 및 약 45kDa 살충성 단백질을 코딩하는식물에 최적화된 폴리뉴클레오티드 |
| JP2002534129A (ja) | 1999-01-14 | 2002-10-15 | モンサント テクノロジー エルエルシー | ダイズ形質転換方法 |
| WO2000053763A1 (en) * | 1999-03-08 | 2000-09-14 | Pioneer Hi-Bred International, Inc. | Maize metallothionein gene and promoter |
| US20100017918A1 (en) | 2000-06-23 | 2010-01-21 | Syngenta Participations Ag | Arabidopsis derived promoters for regulation of plant expression |
| CA2490274A1 (en) | 2002-06-27 | 2004-01-08 | Dow Agrosciences Llc | Use of regulatory sequences in transgenic plants |
| EP1697516B1 (en) | 2003-12-22 | 2010-08-25 | Pioneer Hi-Bred International, Inc. | Maize metallothionein promoter |
| PL2308976T5 (pl) | 2004-04-30 | 2017-10-31 | Dow Agrosciences Llc | Nowe geny odporności na herbicydy |
| MX363711B (es) | 2005-10-28 | 2019-03-29 | Dow Agrosciences Llc | Genes novedosos para resistencia a herbicida. |
| EP2094831B1 (en) | 2006-12-07 | 2015-09-16 | Dow AgroSciences LLC | Novel selectable marker genes |
| CN101889090B (zh) | 2007-10-05 | 2018-01-23 | 陶氏益农公司 | 用于将分子物质转移入植物细胞中的方法 |
| TW201144442A (en) | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
| RU2611188C2 (ru) | 2010-07-29 | 2017-02-21 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Штаммы agrobacterium, модифицированные для увеличения частоты трансформации растений |
| TW201307553A (zh) | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術 |
| AU2012352095A1 (en) | 2011-12-15 | 2014-06-12 | Dow Agrosciences Llc | Method for improved transformation using Agrobacterium |
| RU2636037C2 (ru) | 2012-02-01 | 2017-11-17 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Устойчивые к глифосату растения и способы, связанные с ними |
-
2014
- 2014-10-02 KR KR1020167011722A patent/KR20160065952A/ko not_active Withdrawn
- 2014-10-02 US US14/505,055 patent/US9777286B2/en active Active
- 2014-10-02 AP AP2016009164A patent/AP2016009164A0/en unknown
- 2014-10-02 RU RU2016116914A patent/RU2016116914A/ru not_active Application Discontinuation
- 2014-10-02 JP JP2016519784A patent/JP2016536978A/ja not_active Withdrawn
- 2014-10-02 CN CN201480065991.XA patent/CN105793427A/zh active Pending
- 2014-10-02 WO PCT/US2014/058753 patent/WO2015051075A1/en not_active Ceased
- 2014-10-02 AU AU2014329590A patent/AU2014329590B2/en not_active Ceased
- 2014-10-02 CA CA2926197A patent/CA2926197A1/en not_active Abandoned
- 2014-10-02 EP EP14850603.3A patent/EP3052633B1/en not_active Not-in-force
- 2014-10-03 BR BR102014024813A patent/BR102014024813A2/pt not_active Application Discontinuation
- 2014-10-03 AR ARP140103695A patent/AR097916A1/es unknown
- 2014-10-06 UY UY0001035773A patent/UY35773A/es not_active Application Discontinuation
-
2016
- 2016-04-03 IL IL244866A patent/IL244866A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160065952A (ko) | 2016-06-09 |
| CN105793427A (zh) | 2016-07-20 |
| AU2014329590B2 (en) | 2017-10-19 |
| EP3052633A1 (en) | 2016-08-10 |
| IL244866A0 (en) | 2016-05-31 |
| US20150101083A1 (en) | 2015-04-09 |
| JP2016536978A (ja) | 2016-12-01 |
| BR102014024813A2 (pt) | 2015-10-06 |
| AP2016009164A0 (en) | 2016-04-30 |
| CA2926197A1 (en) | 2015-04-09 |
| EP3052633B1 (en) | 2019-06-12 |
| EP3052633A4 (en) | 2017-04-05 |
| US9777286B2 (en) | 2017-10-03 |
| WO2015051075A1 (en) | 2015-04-09 |
| RU2016116914A (ru) | 2017-11-13 |
| UY35773A (es) | 2015-04-30 |
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