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AR095032A1 - Formulaciones de compuestos orgánicos, composición farmacéutica sólida comprimida por rodillo - Google Patents

Formulaciones de compuestos orgánicos, composición farmacéutica sólida comprimida por rodillo

Info

Publication number
AR095032A1
AR095032A1 ARP140100730A ARP140100730A AR095032A1 AR 095032 A1 AR095032 A1 AR 095032A1 AR P140100730 A ARP140100730 A AR P140100730A AR P140100730 A ARP140100730 A AR P140100730A AR 095032 A1 AR095032 A1 AR 095032A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
solid pharmaceutical
roller
formulations
composition compressed
Prior art date
Application number
ARP140100730A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR095032A1 publication Critical patent/AR095032A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12136Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/1204Type of occlusion temporary occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12068Details concerning the detachment of the occluding device from the introduction device detachable by heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12086Details concerning the detachment of the occluding device from the introduction device magnetically detachable

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Surgical Instruments (AREA)

Abstract

Composiciones farmacéuticas sólidas que comprenden el compuesto inhibidor de fosfatidilinositol 3-quinasa, 4-(trifluorometil)-5-(2,6-dimorfolinopirimidin-4-il)piridin-2-amina o una sal aceptable para uso farmacéutico del mismo, estearil fumarato de sodio, y opcionalmente al menos un vehículo aceptable para uso farmacéutico adicional. También se refiere a los procesos para su preparación y su uso como medicamentos para el tratamiento de cáncer. Reivindicación 1: Una composición farmacéutica sólida comprimida por rodillo que comprende (a) el compuesto 4-(trifluorometil)-5-(2,6-dimorfolinopirimidin-4-il)piridin-2-amina o una sal aceptable para uso farmacéutico del mismo, (b) estearil fumarato de sodio, y (c) opcionalmente al menos un vehículo aceptable para uso farmacéutico adicional. Reivindicación 4: La composición farmacéutica sólida comprimida por rodillo de acuerdo a cualquiera de las reivindicaciones precedentes, en donde la composición farmacéutica contiene una pluralidad de gránulos con una fase interna y una fase externa, y en donde dicha fase interna y fase externa de los gránulos ambas incluyen estearil fumarato de sodio.
ARP140100730A 2013-03-06 2014-03-06 Formulaciones de compuestos orgánicos, composición farmacéutica sólida comprimida por rodillo AR095032A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361773492P 2013-03-06 2013-03-06

Publications (1)

Publication Number Publication Date
AR095032A1 true AR095032A1 (es) 2015-09-16

Family

ID=50342366

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP140100730A AR095032A1 (es) 2013-03-06 2014-03-06 Formulaciones de compuestos orgánicos, composición farmacéutica sólida comprimida por rodillo
ARP230100279A AR128459A2 (es) 2013-03-06 2023-02-06 Composición farmacéutica sólida comprimida por rodillo y el proceso para su fabricación

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP230100279A AR128459A2 (es) 2013-03-06 2023-02-06 Composición farmacéutica sólida comprimida por rodillo y el proceso para su fabricación

Country Status (28)

Country Link
US (2) US9474534B2 (es)
EP (1) EP2964200B1 (es)
JP (1) JP6313343B2 (es)
KR (1) KR102233757B1 (es)
CN (1) CN105073099B (es)
AR (2) AR095032A1 (es)
AU (1) AU2014224238B2 (es)
BR (1) BR112015021097B1 (es)
CA (1) CA2904032C (es)
CL (1) CL2015002466A1 (es)
EA (1) EA028301B1 (es)
ES (1) ES2634020T3 (es)
IL (1) IL240579B (es)
JO (1) JO3256B1 (es)
MA (1) MA38358B1 (es)
MX (1) MX370175B (es)
MY (1) MY174648A (es)
NZ (1) NZ711015A (es)
PE (1) PE20151607A1 (es)
PH (1) PH12015501945B1 (es)
PL (1) PL2964200T3 (es)
PT (1) PT2964200T (es)
SG (1) SG11201506392VA (es)
TN (1) TN2015000386A1 (es)
TW (1) TW201442712A (es)
UA (1) UA114948C2 (es)
WO (1) WO2014136048A1 (es)
ZA (1) ZA201505830B (es)

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US9498604B2 (en) 1997-11-12 2016-11-22 Genesis Technologies Llc Medical device and method
US10335577B2 (en) 2010-05-19 2019-07-02 Nfinium Vascular Technologies, Llc Augmented delivery catheter and method
US9561094B2 (en) 2010-07-23 2017-02-07 Nfinium Vascular Technologies, Llc Devices and methods for treating venous diseases
EP3151904A4 (en) 2014-06-04 2018-02-14 Nfinium Vascular Technologies, LLC Low radial force vascular device and method of occlusion
JP6914202B2 (ja) * 2015-06-30 2021-08-04 ジェネンテック, インコーポレイテッド 薬物を含有する即放性錠剤及び錠剤の形成プロセス
FI130702B1 (en) * 2018-12-18 2024-01-26 Miikka Frant Device suitable for insertion into the vein of a human patient
KR20220012891A (ko) * 2019-05-24 2022-02-04 에자이 알앤드디 매니지먼트 가부시키가이샤 에스트로겐 수용체-알파 억제제의 경구 투여 형태로 암을 치료하는 방법
WO2022066499A1 (en) * 2020-09-27 2022-03-31 Boston Scientific Scimed, Inc. Expandable guide devices, systems, and methods
WO2022170187A1 (en) * 2021-02-05 2022-08-11 Pyne Devaraj Detachable balloon embolization device and methods

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CA2232152C (en) * 1995-12-27 2007-02-06 Janssen Pharmaceutica N.V. Bioadhesive solid dosage form
US5916235A (en) 1997-08-13 1999-06-29 The Regents Of The University Of California Apparatus and method for the use of detachable coils in vascular aneurysms and body cavities
ES2343228T3 (es) * 1998-02-10 2010-07-26 Ethicon Endo-Surgery, Inc. Aparato de oclusion, de anclaje, de tensionado o de direccion por flujo.
US6066157A (en) 1998-09-16 2000-05-23 Medtronics Ave, Inc. Anchor joint for coaxial balloon dilatation catheter
US6368338B1 (en) 1999-03-05 2002-04-09 Board Of Regents, The University Of Texas Occlusion method and apparatus
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TW201036957A (en) * 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
BR112012009496A2 (pt) * 2009-10-23 2015-09-29 Merck Sharp & Dohme composição farmacêutica, e, método para tratar diabetes tipo 2
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WO2014164535A1 (en) 2013-03-11 2014-10-09 Ferry Steven J A guidewire/ partial occluder for intraluminal travel

Also Published As

Publication number Publication date
PT2964200T (pt) 2017-07-25
HK1212244A1 (en) 2016-06-10
NZ711015A (en) 2020-02-28
MY174648A (en) 2020-05-05
CN105073099A (zh) 2015-11-18
EP2964200A1 (en) 2016-01-13
KR102233757B1 (ko) 2021-03-30
EA028301B1 (ru) 2017-10-31
AU2014224238A1 (en) 2015-09-03
UA114948C2 (uk) 2017-08-28
CA2904032C (en) 2021-02-16
AU2014224238B2 (en) 2016-07-14
JP2016510065A (ja) 2016-04-04
IL240579A0 (en) 2015-09-24
ZA201505830B (en) 2017-07-26
BR112015021097B1 (pt) 2022-08-30
MA38358A1 (fr) 2016-11-30
MA38358B1 (fr) 2017-07-31
JP6313343B2 (ja) 2018-04-18
MX370175B (es) 2019-12-04
ES2634020T3 (es) 2017-09-26
WO2014136048A1 (en) 2014-09-12
US10342547B2 (en) 2019-07-09
PE20151607A1 (es) 2015-11-26
US9474534B2 (en) 2016-10-25
JO3256B1 (ar) 2018-09-16
US20160045202A1 (en) 2016-02-18
TW201442712A (zh) 2014-11-16
TN2015000386A1 (en) 2017-01-03
AR128459A2 (es) 2024-05-08
PL2964200T3 (pl) 2017-09-29
SG11201506392VA (en) 2015-09-29
BR112015021097A2 (pt) 2017-07-18
CN105073099B (zh) 2018-10-26
MX2015011705A (es) 2016-05-18
PH12015501945A1 (en) 2016-01-11
CL2015002466A1 (es) 2016-03-04
US20160015643A1 (en) 2016-01-21
IL240579B (en) 2019-08-29
EP2964200B1 (en) 2017-04-19
KR20150123248A (ko) 2015-11-03
PH12015501945B1 (en) 2016-01-11
CA2904032A1 (en) 2014-09-12
EA201591649A1 (ru) 2016-01-29

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