AR094177A1 - Dioxido de cloro estabilizado para el control de la contaminacion en la fermentacion por zymomonas - Google Patents
Dioxido de cloro estabilizado para el control de la contaminacion en la fermentacion por zymomonasInfo
- Publication number
- AR094177A1 AR094177A1 ARP130104910A ARP130104910A AR094177A1 AR 094177 A1 AR094177 A1 AR 094177A1 AR P130104910 A ARP130104910 A AR P130104910A AR P130104910 A ARP130104910 A AR P130104910A AR 094177 A1 AR094177 A1 AR 094177A1
- Authority
- AR
- Argentina
- Prior art keywords
- chlorine dioxide
- zymomonas
- fermentation
- stabilized chlorine
- mixture
- Prior art date
Links
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 title abstract 14
- 241000588901 Zymomonas Species 0.000 title abstract 8
- 239000004155 Chlorine dioxide Substances 0.000 title abstract 7
- 235000019398 chlorine dioxide Nutrition 0.000 title abstract 7
- 238000000855 fermentation Methods 0.000 title abstract 6
- 230000004151 fermentation Effects 0.000 title abstract 6
- 238000011109 contamination Methods 0.000 title abstract 5
- 230000001580 bacterial effect Effects 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 239000003054 catalyst Substances 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 241000894007 species Species 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H8/00—Macromolecular compounds derived from lignocellulosic materials
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L97/00—Compositions of lignin-containing materials
- C08L97/02—Lignocellulosic material, e.g. wood, straw or bagasse
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12H—PASTEURISATION, STERILISATION, PRESERVATION, PURIFICATION, CLARIFICATION OR AGEING OF ALCOHOLIC BEVERAGES; METHODS FOR ALTERING THE ALCOHOL CONTENT OF FERMENTED SOLUTIONS OR ALCOHOLIC BEVERAGES
- C12H1/00—Pasteurisation, sterilisation, preservation, purification, clarification, or ageing of alcoholic beverages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/22—Processes using, or culture media containing, cellulose or hydrolysates thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Si bien el dióxido de cloro se usa, generalmente, para controlar la contaminación bacteriana, se desarrolló un método que permite el uso de dióxido de cloro estabilizado (SCD) para controlar la contaminación durante la fermentación que usa las bacterias Zymomonas como catalizador biológico, aun cuando las Zymomonas son sensibles al dióxido de cloro. Se identificaron parámetros para inocular una composición para fermentación con células de Zymomonas después de transcurrir un período de tiempo después de la adición de SCD. Reivindicación 1: Un método de fermentación para controlar la contaminación bacteriana en un proceso de fermentación caracterizado porque comprende Zymomonas como catalizador biológico; el método comprende: a) proporcionar un medio de crecimiento que tiene el potencial de ser contaminado por una especie bacteriana; b) añadir una cantidad eficaz de dióxido de cloro estabilizado al medio de crecimiento de (a) para formar una mezcla de dióxido de cloro estabilizado, en donde la temperatura de la mezcla de dióxido de cloro estabilizado es mayor que aproximadamente 33ºC; c) inocular la mezcla de (b) con células de Zymomonas a una temperatura adecuada para que las células de Zymomonas produzcan un caldo inoculado; y d) fermentar el caldo inoculado en condiciones adecuadas para el crecimiento de las células de Zymomonas; en donde la contaminación bacteriana se controla durante la fermentación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/721,103 US8846357B2 (en) | 2012-12-20 | 2012-12-20 | Stabilized chlorine dioxide for contamination control in Zymomonas fermentation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR094177A1 true AR094177A1 (es) | 2015-07-15 |
Family
ID=49881094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130104910A AR094177A1 (es) | 2012-12-20 | 2013-12-19 | Dioxido de cloro estabilizado para el control de la contaminacion en la fermentacion por zymomonas |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8846357B2 (es) |
| EP (1) | EP2935597B1 (es) |
| JP (1) | JP2016504032A (es) |
| CN (1) | CN104870648A (es) |
| AR (1) | AR094177A1 (es) |
| AU (1) | AU2013363404B2 (es) |
| BR (1) | BR112015014850B1 (es) |
| CA (1) | CA2892507A1 (es) |
| WO (1) | WO2014099509A1 (es) |
| ZA (1) | ZA201503611B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090087897A1 (en) * | 2007-10-01 | 2009-04-02 | Eric Guy Sumner | Prevention of bacterial growth in fermentation process |
| EP3984366A1 (en) | 2013-08-19 | 2022-04-20 | Syngulon SA | Controlled growth of microorganisms |
| BR102016013836A2 (pt) * | 2016-06-15 | 2017-12-26 | Universidade Estadual De Campinas - Unicamp | Methods of optimization of the wash for the inactivation of micro-organisms deteriorating the brewer fermentation process |
| US11932672B2 (en) | 2017-12-19 | 2024-03-19 | Syngulon S.A. | Fermentation process |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3591515A (en) | 1968-04-16 | 1971-07-06 | Int Dioxide Inc | Pulverulent chlorine dioxide compositions |
| US3585147A (en) | 1969-10-01 | 1971-06-15 | Int Dioxcide Inc | Stabilized chlorine dioxide solutions containing a chloride and processes of making and using same |
| JPS6075289A (ja) * | 1983-09-30 | 1985-04-27 | Hitachi Zosen Corp | 連続発酵によるアルコ−ル生産における発酵液の雑菌汚染防止方法 |
| US4885241A (en) | 1988-10-13 | 1989-12-05 | University Of Queensland | Ethanol production by zymomonas cultured in yeast-conditioned media |
| US4985355A (en) * | 1988-10-13 | 1991-01-15 | University Of Queensland | Ethanol production by zymomonas cultured in yeast-conditioned media |
| US5514583A (en) | 1994-04-15 | 1996-05-07 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US5712133A (en) | 1994-04-15 | 1998-01-27 | Midwest Research Institute | Pentose fermentation by recombinant zymomonas |
| AU2388295A (en) | 1994-04-15 | 1995-11-10 | Midwest Research Institute | Recombinant zymomonas for pentose fermentation |
| US5843760A (en) | 1994-04-15 | 1998-12-01 | Midwest Research Institute | Single zymomonas mobilis strain for xylose and arabinose fermentation |
| US20040044087A1 (en) | 1999-03-05 | 2004-03-04 | Maye John Paul | Use of hop acids in fuel ethanol production |
| US7223575B2 (en) | 2000-05-01 | 2007-05-29 | Midwest Research Institute | Zymomonas pentose-sugar fermenting strains and uses thereof |
| US6419788B1 (en) | 2000-08-16 | 2002-07-16 | Purevision Technology, Inc. | Method of treating lignocellulosic biomass to produce cellulose |
| US6566107B1 (en) | 2000-11-01 | 2003-05-20 | Midwest Research Institute | Recombinant Zymomonas mobilis with improved xylose utilization |
| ATE524491T1 (de) | 2003-05-29 | 2011-09-15 | Genencor Int | Neue trichoderma-gene |
| CA2604964C (en) | 2005-04-12 | 2014-12-16 | E.I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
| US7781191B2 (en) | 2005-04-12 | 2010-08-24 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain a target chemical |
| US20080206215A1 (en) | 2006-02-22 | 2008-08-28 | Allen Michael Ziegler | Apparatus and method for treatment of microorganisms during propagation, conditioning and fermentation |
| BRPI0713406A2 (pt) | 2006-06-13 | 2012-03-20 | Phibro Animal Health Corporation | método para controlar o metabolismo de lactobacilos em pasta em uma usina de produção de etanol |
| US20080026376A1 (en) | 2006-07-11 | 2008-01-31 | Huaming Wang | KEX2 cleavage regions of recombinant fusion proteins |
| US7629156B2 (en) | 2006-09-28 | 2009-12-08 | E.I. Du Pont De Nemours And Company | Ethanol production in fermentation of mixed sugars containing xylose |
| US7741119B2 (en) | 2006-09-28 | 2010-06-22 | E. I. Du Pont De Nemours And Company | Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production |
| US7741084B2 (en) | 2006-09-28 | 2010-06-22 | E. I. Du Pont De Nemours And Company | Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas |
| US8445236B2 (en) | 2007-08-22 | 2013-05-21 | Alliance For Sustainable Energy Llc | Biomass pretreatment |
| WO2009026706A1 (en) | 2007-08-27 | 2009-03-05 | Iogen Energy Corporation | Method for the production of a fermentation product from a pretreated lignocellulosic feedstock |
| EP2192840B1 (en) | 2007-09-28 | 2013-01-09 | E.I. Du Pont De Nemours And Company | Process for preventing bacterial growth in fermentation processes |
| CN101883861B (zh) | 2007-10-30 | 2013-12-11 | 纳幕尔杜邦公司 | 利用hima表达减少的重组发酵单胞菌属菌株从包含木糖的培养基生产乙醇的方法 |
| CN101970671B (zh) | 2007-10-30 | 2015-05-27 | 纳幕尔杜邦公司 | 在包含浓缩糖和乙酸盐的培养基中具有改进的乙醇产量的发酵单胞菌属 |
| JP2011515107A (ja) | 2008-03-27 | 2011-05-19 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 改善されたキシロース資化能を有するザイモモナス(Zymomonas) |
| AU2009228322B2 (en) | 2008-03-27 | 2013-09-26 | Alliance For Sustainable Energy, Llc | High expression Zymomonas promoters |
| JP2010136702A (ja) * | 2008-12-15 | 2010-06-24 | Forestry & Forest Products Research Institute | エタノールの製造方法 |
| US8247208B2 (en) | 2008-12-22 | 2012-08-21 | Alliance For Sustainable Energy Llc | Zymomonas with improved xylose utilization in stress conditions |
| US20110143408A1 (en) | 2009-06-18 | 2011-06-16 | E. I. Du Pont De Nemours And Company | Zymomonas with improved arabinose utilization |
| EP3296394B1 (en) | 2009-09-23 | 2020-11-04 | Danisco US Inc. | Novel glycosyl hydrolase enzymes and uses thereof |
| US8992831B2 (en) | 2009-09-25 | 2015-03-31 | E. I. Du Pont De Nemours And Company | Stabilized chlorine dioxide to preserve carbohydrate feedstocks |
| US8647850B2 (en) | 2009-12-23 | 2014-02-11 | E I Du Pont De Nemours And Company | Process for simultaneous saccharification and fermentation for production of ethanol |
| US8759049B2 (en) | 2010-02-25 | 2014-06-24 | Iogen Energy Corporation | Method for the production of a fermentation product from a sugar hydrolysate |
| US8623623B2 (en) | 2010-06-29 | 2014-01-07 | E I Du Pont De Nemours And Company | Xylose utilization in recombinant Zymomonas |
| US8679822B2 (en) | 2010-06-29 | 2014-03-25 | E I Du Pont De Nemours And Company | Xylose utilization in recombinant zymomonas |
| US8476048B2 (en) | 2010-12-17 | 2013-07-02 | E I Du Pont De Nemours And Company | Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium |
-
2012
- 2012-12-20 US US13/721,103 patent/US8846357B2/en not_active Expired - Fee Related
-
2013
- 2013-12-11 CN CN201380067027.6A patent/CN104870648A/zh active Pending
- 2013-12-11 WO PCT/US2013/074235 patent/WO2014099509A1/en not_active Ceased
- 2013-12-11 JP JP2015549470A patent/JP2016504032A/ja active Pending
- 2013-12-11 CA CA2892507A patent/CA2892507A1/en not_active Abandoned
- 2013-12-11 EP EP13812398.9A patent/EP2935597B1/en active Active
- 2013-12-11 AU AU2013363404A patent/AU2013363404B2/en not_active Ceased
- 2013-12-11 BR BR112015014850-6A patent/BR112015014850B1/pt not_active IP Right Cessation
- 2013-12-19 AR ARP130104910A patent/AR094177A1/es unknown
-
2014
- 2014-08-26 US US14/468,364 patent/US9522203B2/en not_active Expired - Fee Related
-
2015
- 2015-05-21 ZA ZA2015/03611A patent/ZA201503611B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015014850A2 (pt) | 2017-07-11 |
| JP2016504032A (ja) | 2016-02-12 |
| US8846357B2 (en) | 2014-09-30 |
| EP2935597A1 (en) | 2015-10-28 |
| WO2014099509A1 (en) | 2014-06-26 |
| CN104870648A (zh) | 2015-08-26 |
| ZA201503611B (en) | 2016-11-30 |
| US20150359916A1 (en) | 2015-12-17 |
| EP2935597B1 (en) | 2020-07-29 |
| AU2013363404A1 (en) | 2015-06-04 |
| US9522203B2 (en) | 2016-12-20 |
| US20140178956A1 (en) | 2014-06-26 |
| CA2892507A1 (en) | 2014-06-26 |
| AU2013363404B2 (en) | 2017-04-20 |
| BR112015014850B1 (pt) | 2022-02-22 |
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