AR089828A1 - Variantes de lipasa y polinucleotidos que las codifican - Google Patents
Variantes de lipasa y polinucleotidos que las codificanInfo
- Publication number
- AR089828A1 AR089828A1 ARP130100252A ARP130100252A AR089828A1 AR 089828 A1 AR089828 A1 AR 089828A1 AR P130100252 A ARP130100252 A AR P130100252A AR P130100252 A ARP130100252 A AR P130100252A AR 089828 A1 AR089828 A1 AR 089828A1
- Authority
- AR
- Argentina
- Prior art keywords
- lipase
- variants
- variant
- formula
- polinucleotid
- Prior art date
Links
- 102000004882 Lipase Human genes 0.000 title abstract 6
- 108090001060 Lipase Proteins 0.000 title abstract 6
- 239000004367 Lipase Substances 0.000 title abstract 6
- 235000019421 lipase Nutrition 0.000 title abstract 6
- 238000000034 method Methods 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/39—Organic or inorganic per-compounds
- C11D3/3902—Organic or inorganic per-compounds combined with specific additives
- C11D3/3905—Bleach activators or bleach catalysts
- C11D3/3907—Organic compounds
- C11D3/3917—Nitrogen-containing compounds
- C11D3/392—Heterocyclic compounds, e.g. cyclic imides or lactames
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Variantes de lipasa y método para su obtención. Además a polinucleótidos que codifican las variantes; construcciones de ácido nucleico, vectores, y células huéspedes que comprenden los polinucleótidos; y métodos para el uso de las variantes. Planta. Reivindicación 1: Un método para obtener una variante de lipasa, que comprende introducir en una lipasa parental una sustitución en una o más posiciones correspondientes a las posiciones T37, N39, o G91 del polipéptido maduro de SEC ID Nº 2, donde la variante tiene actividad de lipasa y en comparación con la lipasa parental tiene rendimiento mejorado en presencia de un catalizador orgánico seleccionado entre el grupo que consiste en catalizadores orgánicos que tienen la fórmula a) fórmula (1); b) fórmula (2); y c) sus mezclas, donde cada R¹ es independientemente un grupo alquilo ramificado que contiene entre 3 y 24 carbonos o un grupo alquilo lineal que contiene entre 1 y 24 carbonos; y recuperar la variante.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12153817 | 2012-02-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR089828A1 true AR089828A1 (es) | 2014-09-17 |
Family
ID=47664263
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130100252A AR089828A1 (es) | 2012-02-03 | 2013-01-28 | Variantes de lipasa y polinucleotidos que las codifican |
| ARP210101858A AR122864A2 (es) | 2012-02-03 | 2021-07-01 | Variantes de lipasa y polinucleótidos que las codifican |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210101858A AR122864A2 (es) | 2012-02-03 | 2021-07-01 | Variantes de lipasa y polinucleótidos que las codifican |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9394530B2 (es) |
| EP (4) | EP4570895A3 (es) |
| JP (4) | JP2015512613A (es) |
| CN (2) | CN104080908B (es) |
| AR (2) | AR089828A1 (es) |
| DK (1) | DK3211074T3 (es) |
| ES (1) | ES2794644T3 (es) |
| MX (3) | MX353911B (es) |
| WO (1) | WO2013113622A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140014137A1 (en) | 2009-09-18 | 2014-01-16 | Ecolab Usa Inc. | Treatment of non-trans fats with acidic tetra sodium l-glutamic acid, n, n-diacetic acid (glda) |
| WO2013016121A1 (en) | 2011-07-22 | 2013-01-31 | Ticona Llc | Extruder and method for producing high fiber density resin structures |
| MX353911B (es) * | 2012-02-03 | 2018-02-02 | Novozymes As | Variantes de lipasa y polinucleotidos que las codifican. |
| US10253281B2 (en) | 2012-08-20 | 2019-04-09 | Ecolab Usa Inc. | Method of washing textile articles |
| WO2015049370A1 (en) | 2013-10-03 | 2015-04-09 | Novozymes A/S | Detergent composition and use of detergent composition |
| EP3237609B1 (en) * | 2014-12-22 | 2020-03-25 | Novozymes A/S | Detergent compositions, lipase variants and polynucleotides encoding same |
| PT3250670T (pt) * | 2015-01-29 | 2020-05-29 | Ecolab Usa Inc | Método de tratamento de manchas em têxteis |
| EP3317389B1 (en) | 2015-07-03 | 2019-04-10 | Novozymes A/S | Detergent compositions with improved stability in the presence of sulfites |
| EP3950939A3 (en) * | 2015-07-06 | 2022-06-08 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| DE102016204812A1 (de) * | 2016-03-23 | 2017-09-28 | Henkel Ag & Co. Kgaa | Flüssigformulierung enthaltend eine neue Lipase |
| CN108018273B (zh) * | 2018-01-31 | 2020-05-08 | 江南大学 | 一种长链不饱和脂肪酸特异性脂肪酶突变体及其应用 |
| CN108034647B (zh) * | 2018-01-31 | 2020-08-04 | 江南大学 | 一种饱和脂肪酸特异性脂肪酶突变体及其应用 |
| WO2019154955A1 (en) * | 2018-02-08 | 2019-08-15 | Novozymes A/S | Lipase variants and compositions thereof |
| US20240294852A1 (en) * | 2019-08-27 | 2024-09-05 | Novozymes A/S | Composition comprising a lipase |
| PE20251535A1 (es) | 2022-05-14 | 2025-06-05 | Novozymes As | Composiciones y metodos para prevenir, tratar, suprimir y/o eliminar infecciones e infestaciones fitopatogenas |
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| GR76237B (es) | 1981-08-08 | 1984-08-04 | Procter & Gamble | |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| PT97110B (pt) | 1990-03-23 | 1998-11-30 | Gist Brocades Nv | Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes |
| US6395966B1 (en) | 1990-08-09 | 2002-05-28 | Dekalb Genetics Corp. | Fertile transgenic maize plants containing a gene encoding the pat protein |
| EP0548228B1 (en) | 1990-09-13 | 1998-08-12 | Novo Nordisk A/S | Lipase variants |
| US5869438A (en) * | 1990-09-13 | 1999-02-09 | Novo Nordisk A/S | Lipase variants |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| FR2704860B1 (fr) | 1993-05-05 | 1995-07-13 | Pasteur Institut | Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire. |
| US5360569A (en) | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Activation of bleach precursors with catalytic imine quaternary salts |
| US5360568A (en) | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Imine quaternary salts as bleach catalysts |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| FI964808A0 (fi) | 1994-06-03 | 1996-12-02 | Novo Nordisk Biotech Inc | Puhdistetut Myceliophthora lakkaasit ja niitä koodaavat nukleiinihapot |
| JP3167729B2 (ja) | 1994-06-30 | 2001-05-21 | ノボ ノルディスク バイオテック，インコーポレイティド | 無毒、非毒素原性、非病原性の発現系、並びにその中で利用するためのプロモーター及びターミネーター |
| US5534179A (en) | 1995-02-03 | 1996-07-09 | Procter & Gamble | Detergent compositions comprising multiperacid-forming bleach activators |
| US5597936A (en) | 1995-06-16 | 1997-01-28 | The Procter & Gamble Company | Method for manufacturing cobalt catalysts |
| US5576282A (en) | 1995-09-11 | 1996-11-19 | The Procter & Gamble Company | Color-safe bleach boosters, compositions and laundry methods employing same |
| US5817614A (en) | 1996-08-29 | 1998-10-06 | Procter & Gamble Company | Color-safe bleach boosters, compositions and laundry methods employing same |
| CA2268772C (en) | 1996-10-18 | 2008-12-09 | The Procter & Gamble Company | Detergent compositions comprising an amylolytic enzyme and a cationic surfactant |
| US5753599A (en) | 1996-12-03 | 1998-05-19 | Lever Brothers Company, Division Of Conopco, Inc. | Thiadiazole dioxides as bleach enhancers |
| US6218351B1 (en) | 1998-03-06 | 2001-04-17 | The Procter & Gamble Compnay | Bleach compositions |
| EP0971927B1 (en) | 1997-03-07 | 2005-06-15 | The Procter & Gamble Company | Improved methods of making cross-bridged macropolycycles |
| WO1998039406A1 (en) | 1997-03-07 | 1998-09-11 | The Procter & Gamble Company | Bleach compositions |
| US5955310A (en) | 1998-02-26 | 1999-09-21 | Novo Nordisk Biotech, Inc. | Methods for producing a polypeptide in a bacillus cell |
| PH11999002190B1 (en) | 1998-09-01 | 2007-08-06 | Unilever Nv | Composition and method for bleaching a substrate |
| CA2344619C (en) | 1998-10-26 | 2012-01-03 | Novozymes A/S | Constructing and screening a dna library of interest in filamentous fungal cells |
| EP1135392A2 (en) | 1998-11-30 | 2001-09-26 | The Procter & Gamble Company | Process for preparing cross-bridged tetraaza macrocycles |
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| DE10058645A1 (de) | 2000-11-25 | 2002-05-29 | Clariant Gmbh | Verwendung von cyclischen Zuckerketonen als Katalysatoren für Persauerstoffverbindungen |
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| ATE426668T1 (de) * | 2001-01-10 | 2009-04-15 | Novozymes As | Variante eines lipolytischen enzyms |
| AU2002319696B2 (en) | 2001-07-27 | 2007-11-01 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services | Systems for in vivo site-directed mutagenesis using oligonucleotides |
| US20050255544A1 (en) * | 2002-01-16 | 2005-11-17 | Novozymes A/S | Lipolytic enzyme variants and method for their production |
| US7557076B2 (en) * | 2002-06-06 | 2009-07-07 | The Procter & Gamble Company | Organic catalyst with enhanced enzyme compatibility |
| US20060251763A1 (en) * | 2003-06-19 | 2006-11-09 | Patkar Shamkant A | Phospholipase variants |
| GB0325432D0 (en) | 2003-10-31 | 2003-12-03 | Unilever Plc | Ligand and complex for catalytically bleaching a substrate |
| US20050113246A1 (en) | 2003-11-06 | 2005-05-26 | The Procter & Gamble Company | Process of producing an organic catalyst |
| EP1799819B1 (en) * | 2004-09-30 | 2011-03-23 | Novozymes Inc. | Polypeptides having lipase activity and polynucleotides encoding same |
| EP1693440A1 (en) * | 2005-02-22 | 2006-08-23 | The Procter & Gamble Company | Detergent compositions |
| EP1712610B1 (en) * | 2005-02-22 | 2013-11-06 | The Procter and Gamble Company | Detergent Compositions |
| EP1891195B1 (en) * | 2005-06-17 | 2012-10-17 | The Procter and Gamble Company | Organic catalyst with enhanced enzyme compatibility |
| EP1979456A2 (en) * | 2006-01-23 | 2008-10-15 | The Procter & Gamble Company | A composition comprising a lipase and a bleach catalyst |
| BRPI0721103A2 (pt) * | 2006-12-21 | 2014-03-04 | Novozymes As | Lipase, método de determinação do desempenho da digestão in vitro de uma lipase em comparação com uma lipase de referência, uso de uma lipase ou de uma mistura de lipases, composição farmacêutica, e, método para o tratamento de doença |
| US8368348B2 (en) | 2007-09-20 | 2013-02-05 | Semaconnect, Inc. | Automated recharging system |
| CA2711187A1 (en) * | 2008-01-03 | 2009-07-09 | George Shlieout | Pharmaceutical compositions comprising granules of purified microbial lipase and methods for preventing or treating digestive disorders |
| CN101960007A (zh) * | 2008-02-29 | 2011-01-26 | 宝洁公司 | 包含脂肪酶的洗涤剂组合物 |
| MX353911B (es) * | 2012-02-03 | 2018-02-02 | Novozymes As | Variantes de lipasa y polinucleotidos que las codifican. |
-
2013
- 2013-01-25 MX MX2014009052A patent/MX353911B/es active IP Right Grant
- 2013-01-25 DK DK17158945.0T patent/DK3211074T3/da active
- 2013-01-25 CN CN201380007787.8A patent/CN104080908B/zh active Active
- 2013-01-25 JP JP2014555157A patent/JP2015512613A/ja not_active Withdrawn
- 2013-01-25 EP EP25164023.1A patent/EP4570895A3/en active Pending
- 2013-01-25 EP EP17158945.0A patent/EP3211074B1/en active Active
- 2013-01-25 US US14/372,858 patent/US9394530B2/en active Active
- 2013-01-25 EP EP13702608.4A patent/EP2809779B1/en active Active
- 2013-01-25 MX MX2018001443A patent/MX391773B/es unknown
- 2013-01-25 EP EP20157646.9A patent/EP3696265B1/en active Active
- 2013-01-25 ES ES17158945T patent/ES2794644T3/es active Active
- 2013-01-25 CN CN201810015976.4A patent/CN108148823B/zh active Active
- 2013-01-25 WO PCT/EP2013/051417 patent/WO2013113622A1/en not_active Ceased
- 2013-01-28 AR ARP130100252A patent/AR089828A1/es active IP Right Grant
-
2014
- 2014-07-25 MX MX2021013104A patent/MX2021013104A/es unknown
-
2016
- 2016-06-09 US US15/177,879 patent/US10119128B2/en active Active
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2018
- 2018-05-09 JP JP2018090736A patent/JP6751113B2/ja active Active
- 2018-09-26 US US16/142,351 patent/US10927356B2/en active Active
-
2020
- 2020-02-28 JP JP2020033861A patent/JP7194134B2/ja active Active
-
2021
- 2021-07-01 AR ARP210101858A patent/AR122864A2/es unknown
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2022
- 2022-04-21 JP JP2022070278A patent/JP7382443B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |