AR086220A1 - Proceso para la produccion de cloruro de 4-cloroacetoacetilo, y esteres, amidas e imidas del acido 4-cloroacetoacetico - Google Patents
Proceso para la produccion de cloruro de 4-cloroacetoacetilo, y esteres, amidas e imidas del acido 4-cloroacetoaceticoInfo
- Publication number
- AR086220A1 AR086220A1 ARP120101520A ARP120101520A AR086220A1 AR 086220 A1 AR086220 A1 AR 086220A1 AR P120101520 A ARP120101520 A AR P120101520A AR P120101520 A ARP120101520 A AR P120101520A AR 086220 A1 AR086220 A1 AR 086220A1
- Authority
- AR
- Argentina
- Prior art keywords
- chloride
- chloroacetoacetic acid
- production
- chloroacetoacetilo
- imidas
- Prior art date
Links
- UCTNTYHJFWMUBD-UHFFFAOYSA-N 4-chloro-3-oxobutanoic acid Chemical compound OC(=O)CC(=O)CCl UCTNTYHJFWMUBD-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title abstract 2
- WSHVQVCBPLNREW-UHFFFAOYSA-N 4-chloro-3-oxobutanoyl chloride Chemical compound ClCC(=O)CC(Cl)=O WSHVQVCBPLNREW-UHFFFAOYSA-N 0.000 abstract 3
- -1 4-chloroacetoacetic acid ester Chemical class 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- WASQWSOJHCZDFK-UHFFFAOYSA-N diketene Chemical compound C=C1CC(=O)O1 WASQWSOJHCZDFK-UHFFFAOYSA-N 0.000 abstract 2
- VCPNLOMAQUZMBY-UHFFFAOYSA-N 4-chloro-3-oxobutanamide Chemical compound NC(=O)CC(=O)CCl VCPNLOMAQUZMBY-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003949 imides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/58—Preparation of carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
- C07C59/21—Saturated compounds having only one carboxyl group and containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Reivindicación 1: Un proceso para la producción de cloruro de 4-cloroacetoacetilo, que comprende los pasos de (a) alimentar diceteno y cloro en un reactor de capa delgada, y (b) hacer reaccionar el diceteno y el cloro para obtener cloruro de 4-cloroacetoacetilo.Reivindicación 11: Un proceso para la producción de un éster de ácido 4-cloroacetoacético, una amida de ácido 4-cloroacetoacético o una imida de ácido 4-cloroacetoacético, que comprende los pasos (a) transferir cloruro de 4-cloroacetoacetilo obtenido de acuerdo con un proceso de cualquiera de las reivindicaciones que anteceden a un segundo reactor, y (b) hacer reaccionar el cloruro de 4-cloroacetoacetilo con un alcohol o una amina para obtener el éster de ácido 4-cloroacetoacético, amida de ácido 4-cloroacetoacético o una imida de ácido 4-cloroacetoacético.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161480569P | 2011-04-29 | 2011-04-29 | |
| EP11003510A EP2518043A1 (en) | 2011-04-29 | 2011-04-29 | Process for the production of 4-chloroacetyl chloride, 4-chloroacetic acid esters, amides and imides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR086220A1 true AR086220A1 (es) | 2013-11-27 |
Family
ID=44462084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101520A AR086220A1 (es) | 2011-04-29 | 2012-04-27 | Proceso para la produccion de cloruro de 4-cloroacetoacetilo, y esteres, amidas e imidas del acido 4-cloroacetoacetico |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9227905B2 (es) |
| EP (2) | EP2518043A1 (es) |
| JP (1) | JP6012709B2 (es) |
| KR (1) | KR20140025498A (es) |
| CN (1) | CN103492355B (es) |
| AR (1) | AR086220A1 (es) |
| TW (1) | TWI548619B (es) |
| WO (1) | WO2012146604A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105693509B (zh) * | 2016-03-25 | 2018-09-21 | 上海应用技术学院 | 一种连续合成4-氯乙酰乙酸酯类的方法 |
| CN107827728B (zh) * | 2017-11-23 | 2021-02-05 | 山东民基新材料科技有限公司 | 基于回收氯乙酸的氯乙酸重组分的处理方法 |
| CN111203170B (zh) * | 2020-03-16 | 2021-08-17 | 山东昌邑灶户盐化有限公司 | 一种4-氯乙酰乙酸酯类的绿色合成装置 |
| CN114685274A (zh) * | 2020-12-31 | 2022-07-01 | 江西迪赛诺制药有限公司 | 一种制备4-氯乙酰乙酸甲酯的酯化方法 |
| CN113773181B (zh) * | 2021-09-18 | 2024-03-26 | 无棣融川医药化工科技有限公司 | 一种1，3-二氯丙酮的连续流制备方法及微反应系统 |
| CN120987764A (zh) * | 2025-10-22 | 2025-11-21 | 内蒙古华洲药业有限公司 | 4-氯乙酰乙酸乙酯的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH492668A (de) * | 1968-07-04 | 1970-06-30 | Lonza Ag | Verfahren zur Herstellung von Acetessigsäuren |
| US3950412A (en) | 1971-06-08 | 1976-04-13 | Lonza Ltd. | Method for the production of haloacetoacetic acids |
| US4468356A (en) | 1981-04-15 | 1984-08-28 | Eastman Kodak Company | Diketene chlorination method |
| US4473508A (en) | 1982-11-13 | 1984-09-25 | Lonza Ltd. | Process for the production of γ-chloroacetoacetic acid chloride |
| JPH0234333B2 (ja) * | 1983-07-22 | 1990-08-02 | Nippon Synthetic Chem Ind | Ganmaakuroruasetosakusankuroraidonoseizohoho |
| JPS6025955A (ja) * | 1983-07-22 | 1985-02-08 | Nippon Synthetic Chem Ind Co Ltd:The | γ−クロルアセト酢酸エステルの製造方法 |
| JPS6253940A (ja) * | 1985-09-02 | 1987-03-09 | Daicel Chem Ind Ltd | ４−クロルアセト酢酸クロライドの製法 |
| JPS62106040A (ja) * | 1985-11-05 | 1987-05-16 | Daicel Chem Ind Ltd | １，３−ジクロルアセトンの連続製造方法 |
| JPS6413824A (en) | 1987-07-08 | 1989-01-18 | Fujitsu Ltd | Signal detection circuit |
| JP2003113824A (ja) | 2001-10-02 | 2003-04-18 | Hiromi Shimada | クリッパー |
| CN101121688A (zh) | 2007-09-14 | 2008-02-13 | 南开大学 | 合成奥拉西坦的改进方法 |
-
2011
- 2011-04-29 EP EP11003510A patent/EP2518043A1/en not_active Ceased
-
2012
- 2012-04-10 TW TW101112545A patent/TWI548619B/zh not_active IP Right Cessation
- 2012-04-25 WO PCT/EP2012/057529 patent/WO2012146604A1/en not_active Ceased
- 2012-04-25 CN CN201280020003.0A patent/CN103492355B/zh active Active
- 2012-04-25 JP JP2014506841A patent/JP6012709B2/ja active Active
- 2012-04-25 US US14/112,468 patent/US9227905B2/en active Active
- 2012-04-25 EP EP12717671.7A patent/EP2702032B1/en active Active
- 2012-04-25 KR KR1020137031672A patent/KR20140025498A/ko not_active Ceased
- 2012-04-27 AR ARP120101520A patent/AR086220A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014516937A (ja) | 2014-07-17 |
| US20140039217A1 (en) | 2014-02-06 |
| JP6012709B2 (ja) | 2016-10-25 |
| CN103492355B (zh) | 2016-08-10 |
| EP2702032B1 (en) | 2017-07-19 |
| KR20140025498A (ko) | 2014-03-04 |
| EP2702032A1 (en) | 2014-03-05 |
| HK1192878A1 (zh) | 2014-09-05 |
| CN103492355A (zh) | 2014-01-01 |
| WO2012146604A1 (en) | 2012-11-01 |
| TW201242941A (en) | 2012-11-01 |
| TWI548619B (zh) | 2016-09-11 |
| EP2518043A1 (en) | 2012-10-31 |
| US9227905B2 (en) | 2016-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |