AR085906A1 - LEAVING LEAVES CAPABLE OF FERMENTING URONIC ACIDS - Google Patents
LEAVING LEAVES CAPABLE OF FERMENTING URONIC ACIDSInfo
- Publication number
- AR085906A1 AR085906A1 ARP120100845A ARP120100845A AR085906A1 AR 085906 A1 AR085906 A1 AR 085906A1 AR P120100845 A ARP120100845 A AR P120100845A AR P120100845 A ARP120100845 A AR P120100845A AR 085906 A1 AR085906 A1 AR 085906A1
- Authority
- AR
- Argentina
- Prior art keywords
- pentose
- fermentation product
- acid
- fermenting
- uronic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 abstract 6
- 230000004151 fermentation Effects 0.000 abstract 6
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000002972 pentoses Chemical class 0.000 abstract 2
- 210000005253 yeast cell Anatomy 0.000 abstract 2
- AEMOLEFTQBMNLQ-YMDCURPLSA-N D-galactopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-YMDCURPLSA-N 0.000 abstract 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 abstract 1
- ZAQJHHRNXZUBTE-WUJLRWPWSA-N D-xylulose Chemical compound OC[C@@H](O)[C@H](O)C(=O)CO ZAQJHHRNXZUBTE-WUJLRWPWSA-N 0.000 abstract 1
- FNZLKVNUWIIPSJ-RFZPGFLSSA-N D-xylulose 5-phosphate Chemical compound OCC(=O)[C@@H](O)[C@H](O)COP(O)(O)=O FNZLKVNUWIIPSJ-RFZPGFLSSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 229940097043 glucuronic acid Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Cepas de levadura manipuladas mediante ingeniería genética para producir productos de fermentación a partir de ácidos urónicos tales como ácido galacturónico o ácido glucurónico. Para ello, la cepa de levadura fue modificada por introducción de a) genes que codifican enzimas de una vía de plantas de tipo salvaje y que tienen la capacidad de convertir un ácido D-urónico en pentosa-1-fosfato y dióxido de carbono; b) un gen que codifica una enzima con capacidad para convertir una pentosa-1P en una pentosa; y c) genes que codifican enzimas con capacidad para convertir una pentosa en al menos uno entre xilulosa y xilulosa 5-fosfato. La presente se relaciona además con el uso de tales cepas de levadura modificadas genéticamente en la producción de productos de fermentación y con un proceso para producir un producto de fermentación. El proceso comprende los pasos de a) fermentar un medio con una célula de levadura de la presente, con lo cual el medio contiene o es alimentado con una fuente de un ácido urónico; y donde la célula de levadura fermenta al ácido urónico en el producto de fermentación; y, opcionalmente, b) recuperar el producto de fermentación. El producto de fermentación preferido es etanol.Yeast strains manipulated by genetic engineering to produce fermentation products from uronic acids such as galacturonic acid or glucuronic acid. For this, the yeast strain was modified by introducing a) genes that encode enzymes from a wild-type plant pathway and that have the ability to convert a D-uronic acid into pentose-1-phosphate and carbon dioxide; b) a gene that encodes an enzyme capable of converting a pentose-1P into a pentose; and c) genes encoding enzymes capable of converting a pentose into at least one between xylulose and xylulose 5-phosphate. This is also related to the use of such genetically modified yeast strains in the production of fermentation products and to a process to produce a fermentation product. The process comprises the steps of a) fermenting a medium with a yeast cell of the present, whereby the medium contains or is fed with a source of a uronic acid; and where the yeast cell ferments uronic acid in the fermentation product; and, optionally, b) recover the fermentation product. The preferred fermentation product is ethanol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161452366P | 2011-03-14 | 2011-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR085906A1 true AR085906A1 (en) | 2013-11-06 |
Family
ID=45879002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120100845A AR085906A1 (en) | 2011-03-14 | 2012-03-14 | LEAVING LEAVES CAPABLE OF FERMENTING URONIC ACIDS |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR085906A1 (en) |
| WO (1) | WO2012125027A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012143513A2 (en) * | 2011-04-22 | 2012-10-26 | Dsm Ip Assets B.V. | Yeast cell capable of converting sugars including arabinose and xylose |
| CN106191017B (en) * | 2015-05-25 | 2021-12-07 | 中国医学科学院药物研究所 | Uridine-5' -diphosphate apiose/xylose synthetase derived from ornithogalum caudatum, nucleotide sequence and application thereof |
| BR112019006744A2 (en) | 2016-10-03 | 2019-06-25 | Univ California | engineered microorganisms for production of commodity chemicals and cellular biomass |
| WO2020141168A1 (en) | 2018-12-31 | 2020-07-09 | Dsm Ip Assets B.V. | Novel acetyl-transferases |
| CN111440782B (en) * | 2020-04-22 | 2021-09-17 | 青岛大学 | Beta-galactosidase GalA and application thereof |
| CN111748575B (en) * | 2020-06-22 | 2023-03-24 | 华南农业大学 | Method for improving plant saccharification efficiency by down-regulating UXE gene and application thereof |
| CN111849941A (en) * | 2020-08-12 | 2020-10-30 | 青岛大学 | A novel β-galactosidase and its application in degrading lactose in milk |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2679920A1 (en) | 1991-08-02 | 1993-02-05 | Rhone Poulenc Rorer Sa | Highly stable recombinant yeasts for the production of recombinant proteins, their preparation and their use |
| PT1468093E (en) | 2002-01-23 | 2009-04-15 | Royal Nedalco B V | Fermentation of pentose sugars |
| SE0202090D0 (en) | 2002-05-08 | 2002-07-04 | Forskarpatent I Syd Ab | A modified yeast consuming L-arabinose |
| CA2524387C (en) | 2003-05-02 | 2012-12-04 | Natureworks Llc | Modified yeast cells expressing exogenous xylose isomerase |
| SE0302421D0 (en) | 2003-09-11 | 2003-09-11 | Forskarpatent I Syd Ab | Construction of new xylose utilizing Saccharomyces cerevisiae strain |
| SE0400815D0 (en) | 2004-03-26 | 2004-03-26 | Forskarpatent I Syd Ab | Traits in recombinant xylose-growing Saccharomyces cerevisiae strains using genome-wide transcription analysis |
| SE0401303D0 (en) | 2004-05-19 | 2004-05-19 | Forskarpatent I Syd Ab | Ethanol productivities of microbial strains in fermentation of dilute-acid hydrolyzates depending on their furan reduction capacities |
| CN101914462B (en) | 2004-07-16 | 2013-04-24 | Dsm知识产权资产有限公司 | Eukaryotic cell metabolic engineering of xylose fermentation |
| CA2693365A1 (en) | 2007-07-19 | 2009-01-22 | Royal Nedalco B.V. | Novel arabinose-fermenting eukaryotic cells |
| JP5625199B2 (en) | 2008-03-07 | 2014-11-19 | ディーエスエム アイピー アセッツ ビー.ブイ. | Pentose sugar fermentation cell |
| GB0822937D0 (en) | 2008-12-16 | 2009-01-21 | Terranol As | Microorganism |
| FI20086236A0 (en) * | 2008-12-23 | 2008-12-23 | Valtion Teknillinen | Conversion of hexuronic acid to hexaric acid |
| DK2367928T3 (en) | 2008-12-24 | 2018-06-14 | Dsm Ip Assets Bv | XYLOSE ISOMERAS SIGNS AND THEIR USE IN THE FERMENTATION OF PENTOSET SUGAR |
| FR2947233B1 (en) | 2009-06-30 | 2013-02-15 | Zf Systemes De Direction Nacam Sas | ELECTRIC LOCKING SYSTEM OF A STEERING COLUMN AND STEERING COLUMN COMPRISING SUCH A LATCHING SYSTEM |
| US20120184020A1 (en) | 2009-07-09 | 2012-07-19 | Verdezyne, Inc. | Engineered microorganisms with enhanced fermentation activity |
-
2012
- 2012-03-13 WO PCT/NL2012/050151 patent/WO2012125027A1/en not_active Ceased
- 2012-03-14 AR ARP120100845A patent/AR085906A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012125027A1 (en) | 2012-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |