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AR084394A1 - Combinaciones de principios activos con propiedades insecticidas y acaricidas - Google Patents

Combinaciones de principios activos con propiedades insecticidas y acaricidas

Info

Publication number
AR084394A1
AR084394A1 ARP110102099A ARP110102099A AR084394A1 AR 084394 A1 AR084394 A1 AR 084394A1 AR P110102099 A ARP110102099 A AR P110102099A AR P110102099 A ARP110102099 A AR P110102099A AR 084394 A1 AR084394 A1 AR 084394A1
Authority
AR
Argentina
Prior art keywords
alkyl
alkoxy
ring
halogen
amino
Prior art date
Application number
ARP110102099A
Other languages
English (en)
Inventor
Funke Christian Dr
Heike Hungenberg
Fischer Rdiger Dr
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of AR084394A1 publication Critical patent/AR084394A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/34—Nitriles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • A01N43/68—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms with two or three nitrogen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/707—1,2,3- or 1,2,4-triazines; Hydrogenated 1,2,3- or 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/88—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with three ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/22—O-Aryl or S-Aryl esters thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/30—Derivatives containing the group >N—CO—N aryl or >N—CS—N—aryl
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/26—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-nitrogen bonds
    • A01N57/28—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-nitrogen bonds containing acyclic or cycloaliphatic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Las combinaciones de principios activos que están constituidas por los compuestos de la fórmula (1) en combinación con otros principios activos (II) insecticidas son muy adecuadas para combatir parásitos animales tales como insectos y/o acáridos no deseados. Se reivindica también una composición agroquímica y un procedimiento para combatir parásitos.Reivindicación 1: Combinaciones de principios activos que contienen una combinación sinérgicamente activa de al menos un compuesto de la fórmula general (1), en la que R1 representa hidrógeno, amino, hidroxi o alquilo C1-6, alquenilo C2-6, alquinilo C2-6 o cicloalquilo C3-6, dado el caso, respectivamente, monosustituidos o polisustituidos de forma igual o diferente, pudiendo seleccionarse los sustituyentes, independientemente unos de otros, de entre halógeno, ciano, nitro, hidroxilo, alcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, (alcoxi C1-4)carbonilo, alquilamino C1-4, di(alquil C1-4)amino, cicloalquilamino C3-6 o (alquil C1-4)cicloalquilamino C3-6; R2 representa hidrógeno, alquilo C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-6, alcoxi C1-4, alquilamino C1-4, di-(alquil C1-4)amino, cicloalquilamino C3-6, alcoxi carbonilo C1-6 o alquilcarbonilo C1-6; R3 representa hidrógeno o alquilo C1-6, alcoxi C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-12, cicloalquil C3-12-alquilo C1-6, dado el caso, respectivamente, monosustituidos o polisustituidos de forma igual o diferente, pudiendo seleccionarse los sustituyentes, independientemente unos de otros, de entre amino, cicloalquil C3-6-amino, halógeno, ciano, carboxi, carbamoilo, nitro, hidroxilo, alquilo C1-6, haloalquilo C1-6, cicloalquilo C3-6, alcoxi C1-4, haloalcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, alcoxicarbonilo C1-6, alquilcarbonilo C1-6, trialquilsililo C3-6 o un anillo heterocíclico saturado o parcialmente saturado, un anillo aromático o heteroaromático o un anillo heterobicíclico saturado, parcialmente saturado o aromático, estando el anillo o el sistema anular, dado el caso, mono o polisustituido de forma igual o diferente con SF5, halógeno, ciano, nitro, hidroxilo, amino, carboxi, carbamoilo, aminosulfonilo, alquilo C1-6, cicloalquilo C3-6, alcoxi C1-4, haloalquilo C1-6, haloalcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, alquilsulfimino C1-4, alquilsulfimino C1-4-alquilo C1-4, alquilsulfimino C1-4-alquilcarbonilo C2-5, alquilsulfoximino C1-4, alquilsulfoximino C1-4-alquilo C1-4, alquilsulfoximino C1-4-alquilcarbonilo C2-5, alcoxicarbonilo C1-6, alquilcarbonilo C1-6, trialquilsililo C3-6, benciloalquenilo C2-6, alquinilo C2-6, haloalquenilo C2-6, haloalquinilo C2-6, halocicloalquilo C3-6, haloalquiltio C1-4, haloalquilsulfinilo C1-4, haloalquilsulfonilo C1-4, alquilamino C1-4, di-(alquil C1-4)amino, cicloalquilamino C3-6, o un anillo de 3 a 6 miembros, pudiendo estar el anillo sustituido, dado el caso, con alquilo C1-6, halógeno, ciano, nitro, halógeno-alquilo C1-6, alcoxi C1-6 o halógeno-alcoxi C1-6, o R3 representa alcoxicarbonilo C1-6, alquilcarbonilo C1-6, alquilaminocarbonilo C1-6 o dialquil C1-6 aminocarbonilo, o R3 representa además un anillo aromático o heteroaromático de 5 ó 6 miembros monosustituido o polisustituido de forma igual o diferente, un anillo heterociclico parcialmente saturado o un anillo saturado de 4, 5 ó 6 miembros, o un anillo heterobicíclico saturado, parcialmente saturado o aromático, que dado el caso puede contener de uno a tres heteroátomos de la serie O, S o N, seleccionándose los sustituyentes, independientemente unos de otros, de entre SF5, halógeno, ciano, nitro, hidroxilo, amino, carboxilo, carbamoilo, alquilo C1-6, cicloalquilo C3-6, alcoxi C1-4, haloalquilo C1-6, haloalcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, alquilsulfimino C1-4, alquilsulfimino C1-4-alquilo C1-4, alquilsulfimino C1-4-alquilcarbonilo C1-5, alquilsulfoximino C1-4, alquilsulfoximino C1-4-alquilo C1-4, alquilsulfoximino C1-4-alquilcarbonilo C2-5, alcoxicarbonilo C1-6, alquilcarbonilo C1-6, trialquilsililo C3-6, alquenilo C2-6, alquinilo C2-6, haloalquenilo C2-6, haloalquinilo C2-6, halocicloalquilo C3-6, haloalquiltio C1-4, haloalquilsulfinilo C1-4, haloalquilsulfonilo C1-4, alquilamino C1-4, di-(alquil C1-4)amino, cicloalquilamino C3-6, o un anillo de 3 a 6 miembros, pudiendo estar el anillo dado el caso sustituido con alquilo C1-6, halógeno, ciano, nitro, halógenoalquilo C1-6, alcoxi C1-6 o halógenoalcoxi C1-6, R2 y R3 pueden estar unidos uno con otro a través de dos a seis átomos de carbono y formar un anillo, que dado el caso puede contener adicionalmente un átomo adicional de nitrógeno, azufre u oxígeno y, dado el caso, estar sustituido de una a cuatro veces con alquilo C1-2, haloalquilo C1-2, halógeno, ciano, amino, alcoxi C1-2 o haloalcoxi C1-2, R2, R3 representan, además, conjuntamente =S(alquilo C1-4)2, =S(O)(alquilo C1-4)2; R4 representa hidrógeno, halógeno, ciano, nitro, alquilo C1-4, haloalquilo C1-4, alquenilo C2-6, haloalquenilo C2-6, alquinilo C2-6, alcoxi C1-4, haloalcoxi C1-4, SF5, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, haloalquiltio C1-4, haloalquilsulfinilo C1-4, haloalquilsulfonilo C1-4, alquilamino C1-4, di-(alquil C1-4)amino, cicloalquilamino C3-6, (alcoxi C1-4)imino, (alquil C1-4)(alcoxi C1-4)imino, (haloalquil C1-4)(alcoxi C1-4)imino o trialquil C3-6-sililo, o dos R4 forman un anillo a través de átomos de carbono adyacentes, que representa -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH=CH-)2-, -OCH2O-, -O(CH2)2O-, -OCF2O-, -(CF2)2O-, -O(CF2)2O-, -(CH=CH-CH=N)- o -(CH=CH-N=CH)-, dos R4, además, forman, a través de átomos de carbono adyacentes, los anillos condensados siguientes que, dado el caso, están monosustituidos o polisustituidos de forma igual o diferente, pudiendo seleccionarse los sustituyentes, independientemente unos de otros, de entre hidrógeno, alquilo C1-6, cicloalquilo C3-6, haloalquilo C1-6, halocicloalquilo C3-6, halógeno, alcoxi C1-6, alquiltio C1-4(alquilo C1-6), alquilsulfinil C1-4(alquilo C1-6), alquilsulfonil C1-4(alquilo C1-6), alquilamino C1-4, di-(alquil C1-4)amino o cicloalquilamino C3-6, o un resto del grupo de fórmulas (2); n representa 0 a 3; R5 representa alquilo C1-6, cicloalquilo C3-6, haloalquilo C1-6, halocicloalquilo C1-6, alquenilo C2-6, haloalquenilo C2-6, alquinilo C2-6, haloalquinilo C2-6, alcoxi C1-4, haloalcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, haloalquiltio C1-4, haloalquilsulfinilo C1-4, haloalquilsulfonilo C1-4, halógeno, ciano, nitro o trialquilsililo C3-6; Qx representa un anillo aromático o heteroaromático de 5 a 6 miembros dado el caso monosustituido o polisustituido de forma igual o distinta con sustituyentes R7, que puede contener 1 - 3 heteroátomos de la serie N, S, O; A representa -(alquilen C1-6)-, -(alquenilen C2-6)-, -(alquinilen C2-6)-, -R8-(cicloalquil C3-6)-R8-, -R8-O-R8-, -R8-S-R8-, -R8-S(=O)-R8-, -R8-S(=O)2-R8-, -R8-N(alquil C1-6)-R8-, -R8-C=NO(alquil C1-6)-R8, -CH[CO2(alquil C1-6)]-, -R8-C(=O)-R8, -R8-C(=O)NH-R8, R8-C(=O)N(alquil C1-6)-R8, -R8-C(=O)NHNH-R8-, -R8-C(=O)N(alquil C1-6)-NH-R8-, -R8-C(=O)NHN(alquil C1-6)-R8, -R8-O(C=O)-R8, -R8-O(C=O)NH-R8, -R8-O(C=O)N(alquil C1-6)-R8, -R8-S(=O)2NH-R8, -R8-S(=O)2N(alquil C1-6)-R8, -R8-S(C=O)-R8, -R8-S(C=O)NH-R8, -R8-S(C=O)N(alquil C1-6)-R8, -R8-NHNH-R8, -R8-NHN(alquil C1-6)-R8, -R8-N(alquil C1-6)-NH-R8, -R8-N(alquil C1-6)-N(alquil C1-6)-R8, -R8-N=CH-O-R8, -R8-NH(C=O)O-R8, -R8-N(alquil C1-6)-(C=O)O-R8, -R8-NH(C=O)NH-R8, -R8-NH(C=S)NH-R8, -R8-NHS(=O)2-R8, R8-NH-R8, R8-C(=O)-C(=O)-R8, R8-C(OH)-R8, R8-NH(C=O)-R8, R8-Qz-R8, R8-C(N-NR’2)-R8, R8-C(=C-R’2)-R8 o -R8-N(alquil C1-6)S(=O)2-R8, dado el caso monosustituidos o polisustituidos, pudiendo seleccionarse los sustituyentes, independientemente unos de otros, de entre halógeno, ciano, nitro, hidroxilo, alquilo C1-6, alquiloxi C1-6, halógenoalquilo C1-6, amino, (alquil C1-6)amino, di(alquil C1-6)amino, cicloalquilo C3-6, pudiendo contener el -(cicloalquil C3-6)- en el anillo, dado el caso, 1 a 2 heteroátomos seleccionados de la serie N, S, O; R8 representa -(alquilen C1-6)- lineal o ramificado o representa un enlace directo, representando varios R8, independientemente unos de otros, -(alquilen C1-6)- lineal o ramificado o un enlace directo, por ejemplo R8-O-R8- representa -(alquilen C1-6)-O-(alquilen C1-6)-, -(alquilen C1-6)-O-, -O-(alquilen C1-6)- u -O-; representando R’ alquilo, alquilcarbonilo, alquenilo, alquinilo, que, dado el caso, pueden estar monosustituidos o polisustituidos con halógeno; Qz representa un anillo de 3 a 4 miembros, parcialmente saturado o saturado, o de 5 a 6 miembros parcialmente saturado, saturado o aromático o representa un sistema anular bicíclico de 6 a 10 miembros, pudiendo contener el anillo o el sistema anular bicíclico, dado el caso, de 1 a 3 heteroátomos de la serie N, S, O, estando el anillo o el sistema anular bicíclico, dado el caso, monosustituido o polisustituido de forma igual o distinto, y pudiendo seleccionarse los sustituyentes, independientemente unos de otros, de entre alquilo C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-6, haloalquilo C1-6, haloalquenilo C2-6, haloalquinilo C2-6, halocicloalquilo C3-6, halógeno, ciano, carbamoilo, nitro, hidroxilo, alcoxi C1-4, haloalcoxi C1-4, alquiltio C1-4, alquilsulfinilo C1-4, alquilsulfonilo C1-4, haloalquiltio C1-4, haloalquilsulfinilo C1-4, haloalquilsulfonilo C1-4, alquilamino C1-4, di-(alquil C1-4)amino, cicloalquilamino C3-6, (alquil C1-6)carbonilo, (alcoxi C1-6)carbonilo, (alquil C1-6)aminocarbonilo, di-(alquil C1-4)aminocarbonilo; Qy representa un anillo heterocíclico o heteroaromático de 5 ó 6 miembros, parcialmente saturado o saturado o un sistema anular heterobicíclico condensado aromático de 8, 9 ó 10 miembros, estando el anillo o el sistema anular, dado el caso, monosustituido o polisustituido de forma igual o distinta, y pudiendo seleccionarse los
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