AR084308A1 - Compuestos insecticidas derivados de triazol - Google Patents
Compuestos insecticidas derivados de triazolInfo
- Publication number
- AR084308A1 AR084308A1 ARP110104702A ARP110104702A AR084308A1 AR 084308 A1 AR084308 A1 AR 084308A1 AR P110104702 A ARP110104702 A AR P110104702A AR P110104702 A ARP110104702 A AR P110104702A AR 084308 A1 AR084308 A1 AR 084308A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- substituted
- haloalkyl
- substituents
- halogen
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- QWENRTYMTSOGBR-UHFFFAOYSA-N 1H-1,2,3-Triazole Chemical compound C=1C=NNN=1 QWENRTYMTSOGBR-UHFFFAOYSA-N 0.000 title 1
- 239000002917 insecticide Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 23
- -1 cyano, amino Chemical group 0.000 abstract 9
- 229910052736 halogen Inorganic materials 0.000 abstract 9
- 150000002367 halogens Chemical group 0.000 abstract 9
- 125000001424 substituent group Chemical group 0.000 abstract 9
- 125000003118 aryl group Chemical group 0.000 abstract 7
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 6
- 229910052757 nitrogen Inorganic materials 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 4
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 abstract 3
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 3
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 2
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 2
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 2
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 2
- 125000005347 halocycloalkyl group Chemical group 0.000 abstract 2
- 230000000749 insecticidal effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 1
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 1
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 abstract 1
- 241000238876 Acari Species 0.000 abstract 1
- 125000003830 C1- C4 alkylcarbonylamino group Chemical group 0.000 abstract 1
- 241000238631 Hexapoda Species 0.000 abstract 1
- 241000237852 Mollusca Species 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 241000244206 Nematoda Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 241000607479 Yersinia pestis Species 0.000 abstract 1
- 230000000895 acaricidal effect Effects 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000000232 haloalkynyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002013 molluscicidal effect Effects 0.000 abstract 1
- 230000001069 nematicidal effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente se refiere a derivados de triazol de fórmula (1) que presentan actividad insecticida, a procesos e intermediarios para su preparación, a composiciones insecticidas, acaricidas, nematicidas o molusquicidas que los comprenden y a métodos para su uso para combatir y controlar plagas de insectos, ácaros, nemátodos o moluscos.Reivindicación 1: Un compuesto de fórmula (1) donde A1, A2, A3 y A4 son cada uno independientemente C-X o nitrógeno, donde cada X puede ser igual o diferente; R1 es hidrógeno, alquilo C1-4, H2NC(O)-alquilo C1-4, o alquil C1-4carbonilo; R2 es hidrógeno, halógeno, alquilo C1-4, haloalquilo C1-6 o ciano; G1 es oxígeno o azufre; X es hidrógeno, halógeno, ciano, alquiloxi C1-4, alquilo C1-4 o haloalquilo C1-4; Q1 es arilo o heterociclilo, cada uno opcionalmente sustituido por uno a cinco sustituyentes R3, que pueden ser iguales o diferentes; ó Q1 es alquilo C1-8 o alquilo C1-8 sustituido por uno a cinco R4, alquenilo C2-8 o alquenilo C2-8 sustituido por uno a cinco R4, alquinilo C2-8 o alquinilo C2-8 sustituido por uno a cinco R4, cicloalquilo C3-10 o cicloalquilo C3-10 sustituido por uno a cinco R4; R3 se selecciona de ciano, amino, nitro, hidroxi, halógeno, alquilo C1-4, haloalquilo C1-4, alquenilo C2-4, haloalquenilo C2-4, alquinilo C2-4, haloalquinilo C2-4, cicloalquilo C3-6, halocicloalquilo C3-6, alcoxi C1-3, haloalcoxi C1-3, alquil C1-3tio, haloalquil C1-3tio, alquil C1-3sulfinilo, haloalquil C1-3sulfinilo, alquil C1-3sulfonilo, haloalquil C1-3sulfonilo, alquilo C1-4amino, di-(alquil C1-4)amino, alquil C1-4carbonilo, alquil C1-4carboniloxi, alcoxi C1-4carbonilo, alquil C1-4carbonilamino y fenilo; cada R4 es independientemente halógeno, ciano, nitro, hidroxi, alcoxi C1-8, haloalcoxi C1-8, alquil C1-8tio , haloalquil C1-8tio, alquil C1-8sulfinilo, haloalquil C1-8sulfinilo, alquil C1-8sulfonilo, haloalquil C1-8sulfonilo, alquil C1-8carbonilo, alcoxi C1-8carbonilo, arilo o arilo sustituido por uno a cinco R3, o heterociclilo o heterociclilo sustituido por uno a cinco R3; Q2 es un grupo funcional de fórmula (2) donde R7 y R6 son independientemente uno con respecto al otro hidrógeno, ciano, halógeno, alquilo C1-6, haloalquilo C1-6, alcoxi C1-4alquilo C1-4, alquil C1-6tio, haloalquil C1-6tio, alquil C1-6sulfinilo, haloalquil C1-6sulfinilo, alquil C1-6sulfonilo o haloalquil C1-6sulfonilo; R5 es independientemente hidrógeno, hidroxilo, amino, N-alquil C1-6amino, N,N-di(alquil C1-6)amino, alquilo C1-6, cicloalquilo C3-6, alquenilo C2-6, alquinilo C2-6, alquilo C1-6 sustituido por uno a cinco sustituyentes R9, cicloalquilo C3-6 sustituido por uno a cinco sustituyentes R9, alquinilo C2-6 sustituido por uno a cinco sustituyentes R9, alquenilo C2-6 sustituido por uno a cinco sustituyentes R9, arilo o arilo sustituido por uno a cinco sustituyentes R10, heteroarilo o heteroarilo sustituido por uno a cinco sustituyentes R10; cada R9 es independientemente ciano, nitro, amino, hidroxi, halógeno, N-alquil C1-6amino, N,N-di-(alquil C1-6)amino, alcoxi C1-6, alquil C1-6tio, alquil C1-6sulfinilo, arilo o arilo que está sustituido por uno a cinco sustituyentes que se seleccionan independientemente de ciano, nitro, hidroxilo, halógeno, alquilo C1-6, haloalquilo C1-6, alcoxi C1-6 o haloalcoxi C1-6, o heteroarilo o heteroarilo que está sustituido por uno a cinco sustituyentes que se seleccionan independientemente de ciano, nitro, hidroxi, halógeno, alquilo C1-6, haloalquilo C1-6, alcoxi C1-6 o haloalcoxi C1-6; cada R10 es independientemente ciano, nitro, amino, hidroxi, halógeno, alquilo C1-6, haloalquilo C1-6, alcoxi C1-4alquilo C1-4, alquenilo C2-6, haloalquenilo C2-6, alquinilo C2-6, haloalquinilo C2-6, cicloalquilo C3-6, halocicloalquilo C3-6, alcoxi C1-6, haloalcoxi C1-6, alcoxi C1-4alcoxi C1-4, alquil C1-6tio, haloalquil C1-6tio, alquil C1-6sulfinilo, haloalquil C1-6sulfinilo, alquil C1-6sulfonilo, haloalquil C1-6sulfonilo, N-alquil C1-6amino, N,N-di-(alquil C1-6)amino, N,N-di-(alquil C1-6)aminocarbonilo, N,N-di(alquil C1-6)aminosulfonilo, alquil C1-6carbonilo, alquil C1-6carboniloxi, alcoxi C1-6carbonilo, alquil C1-6carbonilamino; o una sal agronómicamente aceptable o N-óxidos de este.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10195762 | 2010-12-17 | ||
| EP10195918 | 2010-12-20 | ||
| EP11179992 | 2011-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR084308A1 true AR084308A1 (es) | 2013-05-08 |
Family
ID=45373708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110104702A AR084308A1 (es) | 2010-12-17 | 2011-12-15 | Compuestos insecticidas derivados de triazol |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130253011A1 (es) |
| EP (1) | EP2651921A1 (es) |
| CN (1) | CN103261188A (es) |
| AR (1) | AR084308A1 (es) |
| BR (1) | BR112013014986A2 (es) |
| UY (1) | UY33808A (es) |
| WO (1) | WO2012080376A1 (es) |
Families Citing this family (71)
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|---|---|---|---|---|
| ES2430067T3 (es) | 2007-03-28 | 2013-11-18 | President And Fellows Of Harvard College | Polipéptidos cosidos |
| DK2603600T3 (da) | 2010-08-13 | 2019-03-04 | Aileron Therapeutics Inc | Peptidomimetiske makrocyklusser |
| CA2852468A1 (en) | 2011-10-18 | 2013-04-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
| HK1205454A1 (en) | 2012-02-15 | 2015-12-18 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| SG10201606775YA (en) | 2012-02-15 | 2016-10-28 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| CA2887285A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
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-
2011
- 2011-12-15 UY UY0001033808A patent/UY33808A/es unknown
- 2011-12-15 AR ARP110104702A patent/AR084308A1/es not_active Application Discontinuation
- 2011-12-15 BR BR112013014986A patent/BR112013014986A2/pt not_active IP Right Cessation
- 2011-12-15 WO PCT/EP2011/072834 patent/WO2012080376A1/en not_active Ceased
- 2011-12-15 US US13/991,731 patent/US20130253011A1/en not_active Abandoned
- 2011-12-15 CN CN201180060041.4A patent/CN103261188A/zh active Pending
- 2011-12-15 EP EP11799161.2A patent/EP2651921A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013014986A2 (pt) | 2016-07-12 |
| EP2651921A1 (en) | 2013-10-23 |
| WO2012080376A1 (en) | 2012-06-21 |
| UY33808A (es) | 2012-07-31 |
| US20130253011A1 (en) | 2013-09-26 |
| CN103261188A (zh) | 2013-08-21 |
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