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AR071334A1 - Gel de quitosano para aplicaciones dermatologicas, proceso de obtencion y uso del mismo - Google Patents

Gel de quitosano para aplicaciones dermatologicas, proceso de obtencion y uso del mismo

Info

Publication number
AR071334A1
AR071334A1 ARP090100136A ARP090100136A AR071334A1 AR 071334 A1 AR071334 A1 AR 071334A1 AR P090100136 A ARP090100136 A AR P090100136A AR P090100136 A ARP090100136 A AR P090100136A AR 071334 A1 AR071334 A1 AR 071334A1
Authority
AR
Argentina
Prior art keywords
extract
gel
chitosan
skin
tissues
Prior art date
Application number
ARP090100136A
Other languages
English (en)
Inventor
Ariel Saul Hason Nisis
Original Assignee
Gynopharm S A
Igloo Zone Chile S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gynopharm S A, Igloo Zone Chile S A filed Critical Gynopharm S A
Publication of AR071334A1 publication Critical patent/AR071334A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Este gel es de aplicacion externa y puede ser usado en pieles irritadas, quemaduras superficiales, dermo-abrasiones, post-peeling, post-láser y en general en pieles erosionadas. Reivindicacion 1: Un gel estable hidrofilo, en base a un polímero para aplicacion topica, caracterizado porque: a) contiene quitosano, b) el quitosano es disuelto mediante la adicion de un solvente, c) contiene una o más sustancias que aumentan la capacidad restauradora de los tejidos, d) contiene preservantes inocuos para la piel. Reivindicacion 2: Un gel de acuerdo a la reivindicacion 1 caracterizado porque el quitosano tiene de un peso molecular entre 25.000 y 1.250.000 g/mol., es el principal constituyente del hidrogel y se encuentra en proporciones que varían entre un 2 y un 8%. Reivindicacion 4: Un gel de acuerdo a las reivindicaciones 1 a 3 caracterizado porque las sustancias de origen natural, que mejoran la capacidad restauradora de tejidos, se seleccionan de extracto de Portulaca oleracea, extracto de Boswellia sacra, extracto de Stellania media, extracto de Plantago mayor, extracto de Caléndula officinalis, extracto de Boswellia carteri, extracto de Commiphora myrrha, extracto de Chamaemelum nobile, extracto de Pelargonium graveolens, pantenol y ácido linoleico.
ARP090100136A 2008-01-18 2009-01-16 Gel de quitosano para aplicaciones dermatologicas, proceso de obtencion y uso del mismo AR071334A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL200800156A CL2008000156A1 (es) 2008-01-18 2008-01-18 Gel estable hidrofilo en base a un polimero para aplicacion topica porque comprende quitosano disuelto en un solvente; proceso para obtener el gel para uso topico antes mencionado; uso del gel.

Publications (1)

Publication Number Publication Date
AR071334A1 true AR071334A1 (es) 2010-06-16

Family

ID=40261146

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100136A AR071334A1 (es) 2008-01-18 2009-01-16 Gel de quitosano para aplicaciones dermatologicas, proceso de obtencion y uso del mismo

Country Status (14)

Country Link
US (1) US20100316739A1 (es)
EP (1) EP2452673B1 (es)
JP (1) JP5615717B2 (es)
CN (1) CN101977589B (es)
AR (1) AR071334A1 (es)
BR (1) BRPI0906932A2 (es)
CA (1) CA2712527C (es)
CL (1) CL2008000156A1 (es)
CO (1) CO6331421A2 (es)
EC (1) ECSP10010352A (es)
ES (1) ES2361459B1 (es)
MX (1) MX2010007902A (es)
PE (1) PE20091363A1 (es)
WO (1) WO2009090624A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101723272B1 (ko) 2011-06-21 2017-04-18 비브이더블유 홀딩 에이쥐 보스웰릭산을 포함하는 메디컬 디바이스
US9480747B2 (en) 2012-01-24 2016-11-01 Bvw Holding Ag Class of anti-adhesion hydrogels with healing aspects
RU2526183C1 (ru) * 2013-02-28 2014-08-20 Федеральное государственное унитарное предприятие Научно-производственный центр "Фармзащита" Федерального медико-биологического агентства (ФГУП НПЦ "Фармзащита" ФМБА России) Гемостатическая противоожоговая ранозаживляющая композиция
BR112016021415A2 (pt) * 2014-03-17 2017-08-15 Gfs Corp Aus Pty Ltd Composições de higienização antimicrobianas, método de higienização ou desinfecção da pele, método de tratamento ou prevenção de uma infecção fúngica da pele e método de desodorização e/ou higienização do ar
CN103919689A (zh) * 2014-03-20 2014-07-16 金红叶纸业集团有限公司 湿巾乳液、湿巾及湿巾的制备方法
GB201501333D0 (en) 2015-01-27 2015-03-11 Medtrade Products Ltd Composition for a wound dressing
GB201501330D0 (en) * 2015-01-27 2015-03-11 Medtrade Products Ltd Composition for a wound dressing
EA026104B1 (ru) * 2015-04-02 2017-03-31 Общество С Ограниченной Ответственностью "Тектум" Кровоостанавливающее и ранозаживляющее средство
US10660945B2 (en) 2015-08-07 2020-05-26 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
US10751444B2 (en) 2015-08-07 2020-08-25 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CN105055582B (zh) * 2015-08-18 2018-09-04 云南同方科技有限公司 一种用于皮肤轻度烧烫伤的配方精油
WO2018005145A1 (en) * 2016-06-28 2018-01-04 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CN110869062A (zh) 2017-07-19 2020-03-06 贝拉英特拉大学 用于在皮肤损伤的处理中局部应用的薄膜及其获得和应用方法
CN108514546B (zh) * 2018-05-14 2020-09-29 山东师范大学 一种二氢杨梅素的壳聚糖水凝胶制剂及制备方法
CN109731021A (zh) * 2019-03-20 2019-05-10 武汉市思泰利医疗器械发展有限公司 一种用于治疗修复造口皮肤的壳聚糖水凝胶及其制备方法
AU2020271339B2 (en) * 2019-04-08 2025-12-11 Medoderm Gmbh Liquid composition for influencing the microbiota on a subject's skin comprising chitosan
EP3996914A4 (en) * 2019-07-11 2023-08-02 Stenco, LLC BIODEGRADABLE MATERIAL
CN111920742A (zh) * 2020-09-18 2020-11-13 微著生物科技(东营)有限责任公司 一种壳聚糖多效修复面膜及制备方法
EP4228595A1 (en) * 2020-10-14 2023-08-23 Medoderm GmbH Liquid composition for use in the prevention or reduction of skin irritation, allergy and/or an infectious disease
DE102021109834A1 (de) * 2021-04-19 2022-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Zusammensetzung zur Desinfektion und für kosmetische Anwendungen
WO2023233299A1 (en) 2022-05-31 2023-12-07 Instituto Politécnico Da Guarda Wound dressing comprising a ph sensor composition and method of producing the same
TR2022019803A1 (tr) * 2022-12-20 2024-07-22 Aüstrateji̇ Geli̇şti̇rme Dai̇resi̇ Başkanliği Melaleuca viridiflora L. ve Boswellia carterii L. İçeren Yara İyi Edici Jel Formülasyonu
US11845859B1 (en) 2023-03-28 2023-12-19 King Faisal University Biopolymer derived from algae
CN118496398B (zh) * 2024-07-16 2024-10-11 广州和佳润颜医药有限公司 一种医用高分子聚合物载体及其作为皮肤保护剂的用途

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659700A (en) * 1984-03-02 1987-04-21 Johnson & Johnson Products, Inc. Chitosan-glycerol-water gel
US5013769A (en) * 1988-08-22 1991-05-07 Medipro Sciences Limited Method of making a hydrogel-forming wound dressing or skin coating material
US5142010A (en) * 1990-05-10 1992-08-25 H. B. Fuller Licensing & Financing Inc. Polymeric biocidal agents
WO1992009636A1 (en) * 1990-11-30 1992-06-11 Baker Cummins Dermatologicals, Inc. Skin protective compositions and method of inhibiting skin irritation
US5420197A (en) 1994-01-13 1995-05-30 Hydromer, Inc. Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
US5620706A (en) 1995-04-10 1997-04-15 Universite De Sherbrooke Polyionic insoluble hydrogels comprising xanthan and chitosan
SE507028C2 (sv) * 1996-08-06 1998-03-16 Medicarb Ab Ny medicinsk användning
DE19719856A1 (de) * 1997-05-12 1998-11-19 Henkel Kgaa Hautpflegemittel
CA2212300A1 (en) 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
DE19826503A1 (de) * 1998-06-13 1999-12-16 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Chitosan und Phospholipiden
US6121375A (en) 1999-02-11 2000-09-19 Hydromer, Inc. Gels formed by the interaction of poly(aldehyde) with various substances
US6602952B1 (en) * 1999-06-11 2003-08-05 Shearwater Corporation Hydrogels derived from chitosan and poly(ethylene glycol) or related polymers
WO2001030407A1 (en) 1999-10-27 2001-05-03 Department Of Atomic Energy A process for manufacture of hydrogels for burn and injury treatment
DE10010199A1 (de) * 2000-03-02 2001-09-06 Beiersdorf Ag Wäßrig-alkoholische Zubereitungen mit einem Gehalt an Chitosan
US6379702B1 (en) 2000-07-05 2002-04-30 Hydromer, Inc. Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
KR100391781B1 (ko) * 2000-12-14 2003-07-16 주식회사 제닉 키토산과 젤라틴으로 조성된 연질 겔
US6521243B2 (en) 2000-12-22 2003-02-18 Pharma C And D, Limited Ionic chitosan -iodine complexes: antiseptic hydrogels and wound healing promoters
AU2002244123A1 (en) 2001-02-23 2002-09-12 Techquip International, Inc. Stacked panel processing apparatus and methods
JP3947391B2 (ja) * 2001-11-28 2007-07-18 独立行政法人 日本原子力研究開発機構 橋かけ構造を有するキチン誘導体及び/又はキトサン誘導体の製造方法
FR2836044A1 (fr) * 2002-02-15 2003-08-22 Octaris Composition pour la reparation et la cicatrisation cutanee comprenant exclusivement un vrai hydrogel physique de chitosane
EP1896092A1 (de) * 2003-05-24 2008-03-12 JUVENA (International) AG Kosmetische oder dermatologische Zubereitung umfassend eine Nährmedienphase
KR100506543B1 (ko) * 2003-08-14 2005-08-05 주식회사 제닉 온도 감응성 상태변화 하이드로겔 조성물 및 그 제조방법
JP2006045181A (ja) * 2003-11-18 2006-02-16 Sekisui Chem Co Ltd 皮膚外用組成物
GB0403938D0 (en) 2004-02-21 2004-03-24 West Pharm Serv Drug Res Ltd Chitosan containing solution
US20050196450A1 (en) * 2004-03-04 2005-09-08 Elka Touitou Method and composition for burned skin
KR100676937B1 (ko) * 2005-06-01 2007-02-02 주식회사 제닉 피부미용 및 상처치료용 수용성 필름 및 그 제조방법
US20070048358A1 (en) * 2005-08-31 2007-03-01 Schorr Phillip A Antimicrobial substrates
US20070237811A1 (en) * 2006-04-10 2007-10-11 Scherr George H Chitosan wound dressing
CN101057953A (zh) * 2006-04-21 2007-10-24 陈祖辉 对付病毒感染疾患的多靶协同防治制剂

Also Published As

Publication number Publication date
ES2361459A8 (es) 2011-07-21
ES2361459A1 (es) 2011-06-17
JP2012515710A (ja) 2012-07-12
JP5615717B2 (ja) 2014-10-29
CN101977589A (zh) 2011-02-16
MX2010007902A (es) 2010-11-25
WO2009090624A2 (es) 2009-07-23
ES2361459B1 (es) 2012-04-24
EP2452673A4 (en) 2013-04-03
CO6331421A2 (es) 2011-10-20
ECSP10010352A (es) 2010-11-30
CN101977589B (zh) 2014-12-10
EP2452673A2 (en) 2012-05-16
PE20091363A1 (es) 2009-10-15
CA2712527A1 (en) 2009-07-23
BRPI0906932A2 (pt) 2015-07-28
CL2008000156A1 (es) 2008-08-01
EP2452673B1 (en) 2017-04-26
WO2009090624A3 (es) 2009-09-11
CA2712527C (en) 2017-02-28
US20100316739A1 (en) 2010-12-16

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