[go: up one dir, main page]

AR079707A1 - Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos - Google Patents

Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos

Info

Publication number
AR079707A1
AR079707A1 ARP100104892A ARP100104892A AR079707A1 AR 079707 A1 AR079707 A1 AR 079707A1 AR P100104892 A ARP100104892 A AR P100104892A AR P100104892 A ARP100104892 A AR P100104892A AR 079707 A1 AR079707 A1 AR 079707A1
Authority
AR
Argentina
Prior art keywords
cell
ovario
chino
hamster
useful
Prior art date
Application number
ARP100104892A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR079707A1 publication Critical patent/AR079707A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/92—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente da a conocer, además de una línea celular aislada 3M, métodos para la preparacion de dicha línea celular y métodos para usar dicha línea celular, por ejemplo para producir una proteína tal como una inmunoglobulina. Reivindicacion 1: Una célula aislada de ovario de hámster chino producido por un método que comprende: adaptar células CHO-DXB11 en un medio libre de componentes animales en suspension durante aproximadamente 83 días, luego subclonar las células dos veces en dicho medio.
ARP100104892A 2009-12-23 2010-12-22 Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos AR079707A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28970309P 2009-12-23 2009-12-23

Publications (1)

Publication Number Publication Date
AR079707A1 true AR079707A1 (es) 2012-02-15

Family

ID=44196101

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100104892A AR079707A1 (es) 2009-12-23 2010-12-22 Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos

Country Status (5)

Country Link
US (4) US9045536B2 (es)
EP (1) EP2516624B1 (es)
AR (1) AR079707A1 (es)
ES (1) ES2776980T3 (es)
WO (1) WO2011079004A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011085095A2 (en) * 2010-01-07 2011-07-14 Dr. Reddy's Laboratories Ltd. Enhanced protein expression
EP2732027B1 (en) 2011-07-12 2017-03-01 Foodchek Systems, Inc. Culture medium, method for culturing salmonella and e. coli and method for detecting salmonella and e. coli
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
JP2016526385A (ja) * 2013-07-06 2016-09-05 カディラ ヘルスケア リミティド モノクローナル抗体の改良された産生方法
CA2925942C (en) * 2013-10-01 2022-05-03 Texcell Detection of rare microbiological nucleic acids
WO2015110526A1 (en) * 2014-01-22 2015-07-30 Antagonis Biotherapeutics Gmbh Novel glycosaminoglycan-antagonising fusion proteins and methods of using same
TWI797060B (zh) 2015-08-04 2023-04-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
CN108884169B (zh) 2016-01-22 2022-03-22 默沙东公司 抗凝血因子xi抗体
CN109476758B (zh) 2016-06-14 2023-05-23 默沙东有限责任公司 抗-凝血因子xi抗体
CA3068685A1 (en) * 2017-06-27 2019-01-03 Ajinomoto Co., Inc. Riboflavin derivative-containing medium
CN107300422A (zh) * 2017-07-27 2017-10-27 广州达意隆包装机械股份有限公司 一种pt100温度传感器的温度转换方法
CN110484465B (zh) * 2019-08-01 2021-06-04 金华康扬环境科技有限公司 一种vbnc细菌的复苏培养基及其制备方法与应用
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
WO2022081799A1 (en) * 2020-10-14 2022-04-21 Viridian Therapeutics, Inc. Compositions and methods for treatment of thyroid eye disease
US20230084477A1 (en) 2021-08-10 2023-03-16 Viridian Therapeutics, Inc. Compositions, doses, and methods for treatment of thyroid eye disease
CN116478913B (zh) * 2023-06-21 2023-08-18 苏州依科赛生物科技股份有限公司 一种cho细胞培养基及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
GB9022545D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Culture medium
KR101086533B1 (ko) 2002-05-24 2011-11-23 쉐링 코포레이션 중화 사람 항-ｉｇｆｒ 항체, 이를 제조하는 방법 및 이를 포함하는 조성물
EP1623011B1 (en) 2003-05-09 2013-01-02 Janssen Biotech, Inc. Il-23p40 specific immunoglobulin derived proteins, compositions, methods and uses
US7491391B2 (en) 2005-06-30 2009-02-17 Centocor, Inc. Anti-IL-23 antibodies, compositions, methods and uses
PT1937721E (pt) 2005-08-25 2010-09-17 Lilly Co Eli Anticorpos anti-il-23
CN101389351B (zh) 2005-12-29 2012-10-10 森托科尔公司 人抗il-23抗体、组合物、方法和用途
CA2655372A1 (en) 2006-06-13 2007-12-21 Zymogenetics, Inc. Il-17 and il-23 antagonists and methods of using the same
PT2170959E (pt) * 2007-06-18 2014-01-07 Merck Sharp & Dohme Anticorpos para o receptor humano de morte programada pd-1

Also Published As

Publication number Publication date
US9624299B2 (en) 2017-04-18
US9045536B2 (en) 2015-06-02
EP2516624A1 (en) 2012-10-31
US20170233477A1 (en) 2017-08-17
WO2011079004A1 (en) 2011-06-30
EP2516624B1 (en) 2020-02-05
ES2776980T3 (es) 2020-08-03
US20160017036A1 (en) 2016-01-21
US20120264170A1 (en) 2012-10-18
US20180201683A1 (en) 2018-07-19
EP2516624A4 (en) 2013-12-18

Similar Documents

Publication Publication Date Title
AR079707A1 (es) Celula aislada de ovario de hamster chino util para la produccion de anticuerpos terapeuticos
AR132549A2 (es) Medio de cultivo para células cho libre de suero que comprende ornitina y putrescina, método para cultivar células cho y método in vitro para producir una proteína
EA201491526A8 (ru) Способ культивирования бычьих и свиных сперматогониальных стволовых клеток без использования клеток-фидеров
BR112017026672A2 (pt) método de implantação de drx, método de configuração de drx e dispositivo relacionado
EA201071058A1 (ru) Получение леналидомида
EA201171018A1 (ru) Биореактор для культивирования клеток млекопитающих
BR112017010793A2 (pt) animal não humano geneticamente modificado, camundongo, métodos para produzir um animal não humano geneticamente modificado e de triagem de candidatos a fármaco direcionados a um antígeno de interesse, e, modelo de camundongo.
EA201791850A1 (ru) Борсодержащие малые молекулы
BR112013027307A2 (pt) método para tratar uma matriz de tecido; matriz de tecido acelular
BRPI0918648A2 (pt) anticorpos multiespecíficos
BR112012015255A2 (pt) "anticorpo, composição farmaceutica, uso de um anticorpo,método de tramento ,ácido nucleico, vetor de espressão, célula hospedeira e método de produção de um anticorpo recobinante"
MY175954A (en) Light-sensitive ion-passing molecules
EA201170638A1 (ru) Способ получения аденовирусных векторов
BR112015025106A2 (pt) método de purificação de proteínas e método de preparação de uma proteína
BR112013030830A2 (pt) processo de preparação de composto da fórmula (i) e estetrol obtido diretamente por meio do processo
MX345399B (es) Metodo de cultivo de celulas animales.
EA201390856A1 (ru) Инактивация вирусов с применением улучшенного способа растворитель-детергент
BR112015021189A2 (pt) métodos de banco de células de alta densidade
RU2013134126A (ru) Способ снижения уровня с-концевого телопептида коллагена 2 типа
BR112015005081A8 (pt) Método para produzir um polissacarídeo capsular tendo um sorotipo de pneumococo
PE20150603A1 (es) Metodo para producir iduronato-2-sulfatasa recombinante
UA107836C2 (uk) Метод лікування хвороби альцгеймера
BR112015022529A2 (pt) meios de cultura de células e processos de produção de anticorpo
SG10201806083RA (en) Microcarrier perfusion culturing methods and uses thereof
MX2020001357A (es) Produccion microbiana de aminas grasas.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal