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MX2020001357A - Produccion microbiana de aminas grasas. - Google Patents

Produccion microbiana de aminas grasas.

Info

Publication number
MX2020001357A
MX2020001357A MX2020001357A MX2020001357A MX2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A
Authority
MX
Mexico
Prior art keywords
fatty amines
microbial production
host cells
production
employing
Prior art date
Application number
MX2020001357A
Other languages
English (en)
Other versions
MX394744B (es
Inventor
G Hom Louis
B Del Cardayre Stephen
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2020001357A publication Critical patent/MX2020001357A/es
Publication of MX394744B publication Critical patent/MX394744B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01042—Hexadecanal dehydrogenase (acylating) (1.2.1.42), i.e. fatty acyl-CoA reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/09—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with a copper protein as acceptor (1.4.9)
    • C12Y104/09001—Methylamine dehydrogenase (amicyanin) (1.4.9.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01019—4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01082—Putrescine aminotransferase (2.6.1.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/08—Transferases for other substituted phosphate groups (2.7.8)
    • C12Y207/08007—Holo-[acyl-carrier-protein] synthase (2.7.8.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01003—Long-chain-fatty-acid-CoA ligase (6.2.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La descripción se refiere a microorganismos recombinantes para la producción de aminas grasas y derivados de las mismas. Se contemplan además células hospederas recombinantes cultivadas así como métodos para producir aminas grasas al emplear estas células hospederas.
MX2020001357A 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas MX394744B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361912184P 2013-12-05 2013-12-05
PCT/US2014/068950 WO2015085271A1 (en) 2013-12-05 2014-12-05 Microbial production of fatty amines

Publications (2)

Publication Number Publication Date
MX2020001357A true MX2020001357A (es) 2020-03-20
MX394744B MX394744B (es) 2025-03-24

Family

ID=52350294

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020001357A MX394744B (es) 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas
MX2016007054A MX2016007054A (es) 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2016007054A MX2016007054A (es) 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas.

Country Status (12)

Country Link
US (2) US10900057B2 (es)
EP (3) EP4163383A1 (es)
JP (3) JP6553610B2 (es)
KR (2) KR102321813B1 (es)
CN (2) CN105874075B (es)
AU (1) AU2014360086B2 (es)
BR (2) BR112016012371B1 (es)
CA (2) CA2932017C (es)
ES (2) ES2932529T3 (es)
MX (2) MX394744B (es)
MY (1) MY180645A (es)
WO (1) WO2015085271A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019020784A2 (pt) 2017-04-03 2020-04-28 Genomatica Inc variantes de tioesterase com atividade melhorada para a produção de derivados de ácidos graxos de cadeia média
EP3844179A4 (en) 2018-08-31 2022-08-31 Genomatica, Inc. XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE
EP4277976A4 (en) * 2021-01-17 2025-03-19 Genomatica, Inc. Methods and compositions for making amide compounds
KR20230160398A (ko) 2021-03-30 2023-11-23 아사히 가세이 가부시키가이샤 카르복실산 환원 활성을 갖는 재조합 폴리펩티드
JPWO2022209994A1 (es) 2021-03-30 2022-10-06
EP4353814A4 (en) 2021-05-19 2025-06-04 Asahi Kasei Kabushiki Kaisha Recombinant microorganism capable of producing diamine and method for producing diamine
CN114437979B (zh) * 2022-02-14 2023-10-24 恒臻(无锡)生物科技有限公司 可降解芥酸酰胺的节杆菌及其获取方法、培养方法和应用
WO2023178211A1 (en) 2022-03-16 2023-09-21 Genomatica, Inc. Microorganisms and methods for production of fatty acid derivatives with reduced levels of byproducts

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JPH03219886A (ja) 1989-07-20 1991-09-27 Quest Internatl Bv デルタ―ラクトンの製造方法
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
AU2005250074B2 (en) 2004-06-04 2011-04-14 Fluxome Sciences A/S Metabolically engineered cells for the production of polyunsaturated fatty acids
MX339812B (es) 2006-03-15 2016-06-08 Dsm Ip Assets B V * Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa.
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
US8110093B2 (en) 2007-03-14 2012-02-07 Ls9, Inc. Process for producing low molecular weight hydrocarbons from renewable resources
EP2594633A1 (en) * 2007-03-28 2013-05-22 LS9, Inc. Enhanced production of fatty acid derivatives
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
EP2283121B1 (en) 2008-05-16 2015-02-11 REG Life Sciences, LLC Methods and compositions for producing hydrocarbons
WO2009142983A1 (en) 2008-05-23 2009-11-26 Alliant Techsystems Inc. Broadband patch antenna and antenna system
CA2738938C (en) 2008-10-07 2019-04-30 Ls9, Inc. Methods and compositions for producing fatty aldehydes
BRPI0920010A2 (pt) * 2008-10-28 2016-04-19 Ls9 Inc métodos para produzir álcool graxo e surfactante
MX368526B (es) * 2008-12-23 2019-10-07 Reg Life Sciences Llc Metodos y composiciones relacionados con tioesterasa enzima.
JP5876822B2 (ja) 2009-04-30 2016-03-02 ゲノマチカ， インク． １，３−ブタンジオールの産生のための生物
MX2012004291A (es) * 2009-10-13 2012-08-17 Genomatica Inc Microorganismos para la produccion de 1,4-butanoidol, 4-hidroxibutanal, 4-hidroxibutiril-coa, putrescina y compuestos y metodos relacionados con los mismos.
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US8859259B2 (en) 2010-02-14 2014-10-14 Ls9, Inc. Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols
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CN104220601A (zh) 2011-12-16 2014-12-17 英威达技术有限责任公司 经与碳储存相关的CoA 依赖性碳链延长制备6 碳化学品的方法
CA2870257C (en) * 2012-04-13 2020-07-28 REG Life Sciences, LLC Microbial production of alkanolamides and amidoamines and uses thereof

Also Published As

Publication number Publication date
MX2016007054A (es) 2016-09-06
CA3114049C (en) 2023-06-13
KR102321813B1 (ko) 2021-11-04
JP7152365B2 (ja) 2022-10-12
CN105874075A (zh) 2016-08-17
JP2021177785A (ja) 2021-11-18
EP3077526A1 (en) 2016-10-12
US10900057B2 (en) 2021-01-26
AU2014360086B2 (en) 2018-04-19
BR112016012371A2 (pt) 2017-09-26
US11814660B2 (en) 2023-11-14
EP3077526B1 (en) 2019-11-20
CN105874075B (zh) 2020-10-23
CN111471723A (zh) 2020-07-31
WO2015085271A1 (en) 2015-06-11
BR112016012371B1 (pt) 2023-03-28
AU2014360086A1 (en) 2016-07-14
EP4163383A1 (en) 2023-04-12
JP6553610B2 (ja) 2019-07-31
KR20160095053A (ko) 2016-08-10
ES2772774T3 (es) 2020-07-08
ES2932529T3 (es) 2023-01-20
EP3077526B8 (en) 2020-01-08
EP3647430A1 (en) 2020-05-06
CA2932017A1 (en) 2015-06-11
CA3114049A1 (en) 2015-06-11
US20210164002A1 (en) 2021-06-03
EP3647430B1 (en) 2022-10-26
MY180645A (en) 2020-12-04
JP2016538870A (ja) 2016-12-15
CA2932017C (en) 2021-05-25
KR20210134820A (ko) 2021-11-10
JP2019205440A (ja) 2019-12-05
BR122020001956B1 (pt) 2023-03-14
MX394744B (es) 2025-03-24
US20190032097A1 (en) 2019-01-31

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