AR079268A1 - Derivados de azabiciclo(3.2.0)hept-3-ilo, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen - Google Patents
Derivados de azabiciclo(3.2.0)hept-3-ilo, su procedimiento de preparacion y las composiciones farmaceuticas que los contienenInfo
- Publication number
- AR079268A1 AR079268A1 ARP100104487A ARP100104487A AR079268A1 AR 079268 A1 AR079268 A1 AR 079268A1 AR P100104487 A ARP100104487 A AR P100104487A AR P100104487 A ARP100104487 A AR P100104487A AR 079268 A1 AR079268 A1 AR 079268A1
- Authority
- AR
- Argentina
- Prior art keywords
- branched
- linear
- azabiciclo
- ilo
- hept
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000742 histaminergic effect Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Abstract
Medicamento que interacciona con los sistemas histaminérgicos centrales. Reivindicacion 1: Compuestos de formula (1) en la que ALK representa una cadena alquileno, W representa un grupo -N(R')C(=O)R o -C(=O)N(R')R en el que R y R' representan, independientemente el uno del otro, un átomo de hidrogeno o un grupo alquilo C1-6 lineal o ramificado sustituido opcionalmente con uno o varios grupos elegidos entre halogeno, hidroxi y alcoxi, entendiéndose que el término alquileno designa un radical bivalente, lineal o ramificado, que contiene de 2 a 6 átomos de carbono, el término alcoxi designa un grupo alquil-oxi cuya cadena alquilo, lineal o ramificada, contiene de 1 a 6 átomos de carbono, sus enantiomeros y diastereoisomeros, así como sus sales de adicion a un ácido o a una base farmacéuticamente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0905957A FR2953514B1 (fr) | 2009-12-09 | 2009-12-09 | Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR079268A1 true AR079268A1 (es) | 2012-01-04 |
Family
ID=42133738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104487A AR079268A1 (es) | 2009-12-09 | 2010-12-06 | Derivados de azabiciclo(3.2.0)hept-3-ilo, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen |
Country Status (44)
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI9300625B (sl) * | 1993-12-02 | 2002-02-28 | Basf Aktiengesellschaft | N-substituirani derivati azabicikloheptana, njihova priprava in uporaba |
| DE4341402A1 (de) * | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
| DE4427647A1 (de) * | 1994-08-04 | 1996-02-08 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
| FR2866647B1 (fr) * | 2004-02-20 | 2006-10-27 | Servier Lab | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2009
- 2009-12-09 FR FR0905957A patent/FR2953514B1/fr not_active Expired - Fee Related
-
2010
- 2010-11-19 MY MYPI2010005458 patent/MY150598A/en unknown
- 2010-11-21 IL IL209463A patent/IL209463A/en not_active IP Right Cessation
- 2010-11-22 JO JO2010408A patent/JO2880B1/en active
- 2010-11-22 UY UY0001033046A patent/UY33046A/es unknown
- 2010-11-23 SG SG2010085959A patent/SG172543A1/en unknown
- 2010-11-24 CR CR11811A patent/CR11811A/es not_active Application Discontinuation
- 2010-11-25 PE PE2010001083A patent/PE20110542A1/es not_active Application Discontinuation
- 2010-11-25 AU AU2010246426A patent/AU2010246426B2/en not_active Ceased
- 2010-11-26 TW TW099141093A patent/TWI419875B/zh not_active IP Right Cessation
- 2010-11-26 CL CL2010001309A patent/CL2010001309A1/es unknown
- 2010-11-29 CN CN2010105733405A patent/CN102127004B/zh not_active Expired - Fee Related
- 2010-11-29 CO CO10150441A patent/CO6280059A1/es active IP Right Grant
- 2010-11-30 MX MX2010013093A patent/MX2010013093A/es active IP Right Grant
- 2010-12-01 EC EC2010010649A patent/ECSP10010649A/es unknown
- 2010-12-01 MA MA33380A patent/MA32444B1/fr unknown
- 2010-12-01 AP AP2010005489A patent/AP2755A/xx active
- 2010-12-01 ZA ZA2010/08651A patent/ZA201008651B/en unknown
- 2010-12-02 CU CU2010000236A patent/CU23993B1/es not_active IP Right Cessation
- 2010-12-02 SV SV2010003746A patent/SV2010003746A/es unknown
- 2010-12-02 NI NI201000206A patent/NI201000206A/es unknown
- 2010-12-03 CA CA2724151A patent/CA2724151C/fr not_active Expired - Fee Related
- 2010-12-06 UA UAA201014568A patent/UA106721C2/uk unknown
- 2010-12-06 AR ARP100104487A patent/AR079268A1/es unknown
- 2010-12-07 SA SA110320007A patent/SA110320007B1/ar unknown
- 2010-12-07 GE GEAP201012026A patent/GEP20135801B/en unknown
- 2010-12-07 US US12/928,237 patent/US8008337B2/en not_active Expired - Fee Related
- 2010-12-07 NZ NZ589763A patent/NZ589763A/en not_active IP Right Cessation
- 2010-12-07 EA EA201001755A patent/EA018971B1/ru not_active IP Right Cessation
- 2010-12-07 KR KR1020100124116A patent/KR101292705B1/ko not_active Expired - Fee Related
- 2010-12-08 EP EP10290642A patent/EP2332910B1/fr active Active
- 2010-12-08 PT PT102906427T patent/PT2332910E/pt unknown
- 2010-12-08 SI SI201030183T patent/SI2332910T1/sl unknown
- 2010-12-08 ES ES10290642T patent/ES2405206T3/es active Active
- 2010-12-08 HN HN2010002593A patent/HN2010002593A/es unknown
- 2010-12-08 PL PL10290642T patent/PL2332910T3/pl unknown
- 2010-12-08 RS RS20130092A patent/RS52698B/sr unknown
- 2010-12-08 BR BRPI1005270-4A patent/BRPI1005270A2/pt not_active IP Right Cessation
- 2010-12-08 ME MEP-2013-42A patent/ME01504B/me unknown
- 2010-12-08 DK DK10290642.7T patent/DK2332910T3/da active
- 2010-12-08 WO PCT/FR2010/000820 patent/WO2011070250A1/fr not_active Ceased
- 2010-12-09 JP JP2010274280A patent/JP5511645B2/ja not_active Expired - Fee Related
-
2013
- 2013-04-04 HR HRP20130307AT patent/HRP20130307T1/hr unknown
- 2013-04-29 CY CY20131100354T patent/CY1113971T1/el unknown
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| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |