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AR077642A1 - METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME - Google Patents

METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME

Info

Publication number
AR077642A1
AR077642A1 ARP100102446A ARP100102446A AR077642A1 AR 077642 A1 AR077642 A1 AR 077642A1 AR P100102446 A ARP100102446 A AR P100102446A AR P100102446 A ARP100102446 A AR P100102446A AR 077642 A1 AR077642 A1 AR 077642A1
Authority
AR
Argentina
Prior art keywords
disorders related
treatment
same
metabolism modulators
metabolism
Prior art date
Application number
ARP100102446A
Other languages
Spanish (es)
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of AR077642A1 publication Critical patent/AR077642A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composicion farmacéutica de N-(2-fluoro-4-(metilsulfonil)fenil)-5-metil-6-(1-(5-metilpirazin-2-il)piperidin-4-iloxi)pirimidin-4-amina, utiles en el tratamiento de trastornos relacionados con GPR119, tales como trastornos relacionados con el metabolismo y complicaciones de los mismos, tales como la diabetes y la obesidad. Reivindicacion 1: Un compuesto seleccionado del compuesto de formula (1) y sales, solvatos e hidratos farmacéuticamente aceptables del mismo.Pharmaceutical composition of N- (2-fluoro-4- (methylsulfonyl) phenyl) -5-methyl-6- (1- (5-methylpyrazin-2-yl) piperidin-4-yloxy) pyrimidin-4-amine, useful in the treatment of disorders related to GPR119, such as disorders related to metabolism and complications thereof, such as diabetes and obesity. Claim 1: A compound selected from the compound of formula (1) and pharmaceutically acceptable salts, solvates and hydrates thereof.

ARP100102446A 2009-07-09 2010-07-07 METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME AR077642A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27050209P 2009-07-09 2009-07-09

Publications (1)

Publication Number Publication Date
AR077642A1 true AR077642A1 (en) 2011-09-14

Family

ID=42751753

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100102446A AR077642A1 (en) 2009-07-09 2010-07-07 METABOLISM MODULATORS AND THE TREATMENT OF DISORDERS RELATED TO THE SAME

Country Status (3)

Country Link
AR (1) AR077642A1 (en)
TW (1) TW201105327A (en)
WO (1) WO2011005929A1 (en)

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JP6838744B2 (en) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド (R) -2- (7- (4-cyclopentyl-3- (trifluoromethyl) benzyloxy) -1,2,3,4-tetrahydrocyclopenta [b] indole-for use in S1P1 receptor-related disorders Crystalline L-arginine salt of 3-yl) acetic acid (Compound 1)
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
KR102859841B1 (en) 2018-06-06 2025-09-12 아레나 파마슈티칼스, 인크. Treatment of conditions associated with the S1P1 receptor
AU2024250528A1 (en) * 2023-04-14 2025-10-23 Pfizer Inc. Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
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WO2025224599A1 (en) * 2024-04-22 2025-10-30 Pfizer Inc. Pyrrolidine-based glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof

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