AR077115A1 - Produccion de isopreno usando las vias de mevalonato (mva) y la de no mevalonato (dxp) - Google Patents
Produccion de isopreno usando las vias de mevalonato (mva) y la de no mevalonato (dxp)Info
- Publication number
- AR077115A1 AR077115A1 ARP100102132A AR077115A1 AR 077115 A1 AR077115 A1 AR 077115A1 AR P100102132 A ARP100102132 A AR P100102132A AR 077115 A1 AR077115 A1 AR 077115A1
- Authority
- AR
- Argentina
- Prior art keywords
- polypeptide
- dxp
- mva
- mevalonate
- pathway
- Prior art date
Links
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 title abstract 6
- KJTLQQUUPVSXIM-ZCFIWIBFSA-M (R)-mevalonate Chemical compound OCC[C@](O)(C)CC([O-])=O KJTLQQUUPVSXIM-ZCFIWIBFSA-M 0.000 title 2
- KJTLQQUUPVSXIM-UHFFFAOYSA-N DL-mevalonic acid Natural products OCCC(O)(C)CC(O)=O KJTLQQUUPVSXIM-UHFFFAOYSA-N 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 abstract 9
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 9
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 9
- 230000037361 pathway Effects 0.000 abstract 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 3
- 229910052742 iron Inorganic materials 0.000 abstract 3
- 108010075483 isoprene synthase Proteins 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 239000011593 sulfur Substances 0.000 abstract 3
- 210000004748 cultured cell Anatomy 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Se provee métodos para producir isopreno a partir de células cultivadas usando diversos componentes de la vía DXP y MVA, o componentes asociados con la vía DXP y la vía MVA, polipéptido redox que interactua con el cumulo de hierro y azufres e isopreno sintasa. También se provee composiciones que incluyen estas células cultivadas. Los métodos para produccion de isopreno son de utilidad en la industria de cubiertas y gomas. Reivindicacion 1: Células que comprenden (i) un ácido nucleico heterologo que codifica un polipéptido redox que interactua con el cumulo de hierro y azufre, un polipéptido de la vía DXP, un polipéptido de fa vía MVA y un polipéptido de isopreno sintasa o (ii) una copia duplicada de un ácido nucleico endogeno que codifica un polipéptido redox que interactua con el cumulo de hierro y azufre, un polipéptido de la vía DXP, un polipéptido de la vía MVA y un polipéptido de isopreno sintasa.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18794109P | 2009-06-17 | 2009-06-17 | |
| US18793009P | 2009-06-17 | 2009-06-17 | |
| US31498510P | 2010-03-17 | 2010-03-17 | |
| US31497910P | 2010-03-17 | 2010-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR077115A1 true AR077115A1 (es) | 2011-08-03 |
Family
ID=43356749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100102132 AR077115A1 (es) | 2009-06-17 | 2010-06-16 | Produccion de isopreno usando las vias de mevalonato (mva) y la de no mevalonato (dxp) |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8507235B2 (es) |
| EP (1) | EP2443244A4 (es) |
| CN (1) | CN102753697A (es) |
| AR (1) | AR077115A1 (es) |
| BR (1) | BRPI1014123A2 (es) |
| CA (1) | CA2765805A1 (es) |
| MY (1) | MY158160A (es) |
| SG (2) | SG10201403297UA (es) |
| TW (2) | TW201412988A (es) |
| WO (1) | WO2010148150A1 (es) |
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| AU2010295739B2 (en) | 2009-09-15 | 2016-02-25 | Renew Biopharma, Inc. | A system for transformation of the chloroplast genome of Scenedesmus sp. and Dunaliella sp. |
| WO2011075534A2 (en) | 2009-12-18 | 2011-06-23 | Danisco Us Inc. | Purification of isoprene from renewable resources |
| SG190043A1 (en) | 2010-10-27 | 2013-06-28 | Danisco Us Inc | Isoprene synthase variants for improved production of isoprene |
| CN103476926A (zh) | 2010-12-22 | 2013-12-25 | 丹尼斯科美国公司 | 使用两种类型的ispg酶改善异戊二烯产量的组合物和方法 |
| CN103403145A (zh) | 2010-12-22 | 2013-11-20 | 丹尼斯科美国公司 | 使用重组细胞进行戊糖的生物制备 |
-
2010
- 2010-06-15 TW TW102141532A patent/TW201412988A/zh unknown
- 2010-06-15 TW TW99119621A patent/TWI427149B/zh not_active IP Right Cessation
- 2010-06-16 SG SG10201403297UA patent/SG10201403297UA/en unknown
- 2010-06-16 BR BRPI1014123A patent/BRPI1014123A2/pt not_active IP Right Cessation
- 2010-06-16 AR ARP100102132 patent/AR077115A1/es unknown
- 2010-06-16 SG SG2011094562A patent/SG176936A1/en unknown
- 2010-06-16 MY MYPI2011006126A patent/MY158160A/en unknown
- 2010-06-16 US US12/817,134 patent/US8507235B2/en not_active Expired - Fee Related
- 2010-06-16 EP EP10790161.3A patent/EP2443244A4/en not_active Withdrawn
- 2010-06-16 CN CN2010800359758A patent/CN102753697A/zh active Pending
- 2010-06-16 WO PCT/US2010/038904 patent/WO2010148150A1/en not_active Ceased
- 2010-06-16 CA CA2765805A patent/CA2765805A1/en not_active Abandoned
-
2013
- 2013-07-11 US US13/940,092 patent/US20140162337A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2765805A1 (en) | 2010-12-23 |
| WO2010148150A1 (en) | 2010-12-23 |
| US8507235B2 (en) | 2013-08-13 |
| MY158160A (en) | 2016-09-15 |
| TW201111512A (en) | 2011-04-01 |
| BRPI1014123A2 (pt) | 2019-07-02 |
| EP2443244A4 (en) | 2014-11-26 |
| SG10201403297UA (en) | 2014-10-30 |
| CN102753697A (zh) | 2012-10-24 |
| EP2443244A1 (en) | 2012-04-25 |
| SG176936A1 (en) | 2012-02-28 |
| US20140162337A1 (en) | 2014-06-12 |
| US20110014672A1 (en) | 2011-01-20 |
| TW201412988A (zh) | 2014-04-01 |
| TWI427149B (zh) | 2014-02-21 |
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