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AR076832A1 - Derivados de 1- amino-alquilciclohexano para el tratamiento de enfermedades inflamatorias de la piel - Google Patents

Derivados de 1- amino-alquilciclohexano para el tratamiento de enfermedades inflamatorias de la piel

Info

Publication number
AR076832A1
AR076832A1 ARP090105019A ARP090105019A AR076832A1 AR 076832 A1 AR076832 A1 AR 076832A1 AR P090105019 A ARP090105019 A AR P090105019A AR P090105019 A ARP090105019 A AR P090105019A AR 076832 A1 AR076832 A1 AR 076832A1
Authority
AR
Argentina
Prior art keywords
amino
treatment
skin diseases
inflammatory skin
alquilciclohexano
Prior art date
Application number
ARP090105019A
Other languages
English (en)
Inventor
Peter Boderke
Alexander Gebauer
Bernhard Hauptmeier
Rainer Pooth
Bhushan Hardas
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of AR076832A1 publication Critical patent/AR076832A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/17—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing only non-condensed rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Tratamiento de un individuo afectado por enfermedades inflamatorias de la piel, en el cual se utiliza un derivado de 1-amino-alquilciclohexano, en particular neramexano y sales farmacéuticamente aceptables de éste.
ARP090105019A 2008-12-19 2009-12-21 Derivados de 1- amino-alquilciclohexano para el tratamiento de enfermedades inflamatorias de la piel AR076832A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20319508P 2008-12-19 2008-12-19
EP09001448 2009-02-03

Publications (1)

Publication Number Publication Date
AR076832A1 true AR076832A1 (es) 2011-07-13

Family

ID=40651362

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090105019A AR076832A1 (es) 2008-12-19 2009-12-21 Derivados de 1- amino-alquilciclohexano para el tratamiento de enfermedades inflamatorias de la piel

Country Status (15)

Country Link
US (3) US8394857B2 (es)
EP (1) EP2373303A1 (es)
JP (1) JP5542835B2 (es)
KR (1) KR101308331B1 (es)
CN (1) CN102149373B (es)
AR (1) AR076832A1 (es)
AU (1) AU2009328499B2 (es)
BR (1) BRPI0922482A2 (es)
CA (1) CA2734677C (es)
IL (1) IL213606A0 (es)
MX (1) MX2011006354A (es)
RU (2) RU2481828C2 (es)
TW (1) TWI432188B (es)
WO (1) WO2010069597A1 (es)
ZA (1) ZA201101821B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399519B2 (en) 2008-12-19 2013-03-19 Merz Pharma Gmbh & Co. Kgaa 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases
TWI432188B (zh) * 2008-12-19 2014-04-01 Merz Pharma Gmbh & Co Kgaa 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類
BRPI1012669A2 (pt) * 2009-06-29 2016-04-05 Merz Pharma Gmbh & Co Kgaa metodo de preparacao de 3,3,5,5-tetrametliciclohexanona, método de preparção de 1-amino-1,3,3,5,5,-pentametilciclohexano ou um sal farmaceuticamente aceitável do mesmo e composto
RU2013102263A (ru) * 2010-06-18 2014-07-27 Мерц Фарма Гмбх Унд Ко. Кгаа Гелевые лекарственные формы для местного применения производных 1-аминоалкилциклогексана

Family Cites Families (32)

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US5811128A (en) 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US4849222A (en) 1987-03-24 1989-07-18 The Procter & Gamble Company Mixtures for treating hypercholesterolemia
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
US5288502A (en) 1991-10-16 1994-02-22 The University Of Texas System Preparation and uses of multi-phase microspheres
ES2184769T3 (es) 1993-10-22 2003-04-16 Genentech Inc Metodos y composiciones para microencapsulacion de antigenos para utilizar como vacunas.
ATE189211T1 (de) 1994-06-01 2000-02-15 Axys Pharm Inc Zusammensetzungen und verfahren zur behandlung von durch mast-zellen verursachten krankheiten
FI990171A7 (fi) 1996-07-30 1999-03-23 Arris Pharm Corp Uusia yhdisteitä ja koostumuksia tryptaasiaktiivisuuden liittyvien tau tien hoitamiseksi
ATE219044T1 (de) 1997-04-10 2002-06-15 Pfizer Fluorosubstituierte adamantan-derivate
DK1009732T3 (da) 1997-06-30 2003-09-22 Merz Pharma Gmbh & Co Kgaa 1-Amino-alkylcyclohexan NMDA receptor antagonister
US6071966A (en) 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists
FR2768624B1 (fr) 1997-09-25 1999-11-12 Oreal Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue
SE9801494D0 (sv) 1998-04-28 1998-04-28 Astra Pharma Prod Novel use
PL190755B1 (pl) * 1999-01-07 2006-01-31 Pharmena Sp Z Oo Preparat do leczenia i profilaktyki chorób skóry
TW593223B (en) * 2000-06-20 2004-06-21 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists
FR2813189B1 (fr) 2000-08-31 2003-02-28 Oreal Creme cosmetique moussante pour le traitement des peaux grasses
US20040102525A1 (en) 2002-05-22 2004-05-27 Kozachuk Walter E. Compositions and methods of treating neurological disease and providing neuroprotection
DE10252665A1 (de) 2002-11-11 2004-06-03 Grünenthal GmbH 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate
US7135575B2 (en) * 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
KR20070104480A (ko) 2003-05-27 2007-10-25 포레스트 래보러토리즈, 인코포레이티드 우울증 및 그 밖의 기분장애의 치료를 위한 ｎｍｄａ수용체 길항제 및 선택적 세로토닌 재흡수 억제제의 배합물
US20070082956A1 (en) * 2003-07-28 2007-04-12 Merz Pharma Gmbh & Co. Kgaa The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity.
AR046314A1 (es) 2003-11-05 2005-11-30 Merz Pharma Gmbh & Co Kgaa Composiciones que comprenden ciclohexilaminas y aminoadamantanos
US20050137122A1 (en) 2003-12-17 2005-06-23 Alcon, Inc. Use of agents that prevent generation of amyloid and amyloid-like lipoproteins, and/or use of agents that promote sequestration and/or degradation of, and/or prevent neurotoxicity of such proteins in the treatment of hearing loss and improving body balance
US20050196418A1 (en) 2004-03-04 2005-09-08 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20060002999A1 (en) 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
EP1764095A1 (en) * 2005-09-20 2007-03-21 Revotar Biopharmaceuticals AG Novel nitrocatechol derivatives having selectin ligand activity
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet
CA2637027A1 (en) 2006-01-10 2007-07-19 Ruey J. Yu N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use
MX2008011236A (es) 2006-03-01 2009-02-10 Tristrata Inc Composicion y metodo para tratamiento topico de trastornos dermatologicos que responden a alquitran.
TW200819458A (en) 2006-06-23 2008-05-01 Merz Pharma Gmbh & Co Kgaa Metabotropic glutamate receptor modulators
DE102007003582A1 (de) 2007-01-24 2008-07-31 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Verwendung einer kosmetischen Zusammensetzung zur kosmetischen Behandlung der Haut
US8399519B2 (en) 2008-12-19 2013-03-19 Merz Pharma Gmbh & Co. Kgaa 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases
TWI432188B (zh) * 2008-12-19 2014-04-01 Merz Pharma Gmbh & Co Kgaa 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類

Also Published As

Publication number Publication date
BRPI0922482A2 (pt) 2015-12-15
CN102149373A (zh) 2011-08-10
EP2373303A1 (en) 2011-10-12
CN102149373B (zh) 2012-10-10
ZA201101821B (en) 2012-01-25
RU2013105513A (ru) 2014-08-20
HK1158954A1 (en) 2012-07-27
RU2011129815A (ru) 2013-01-27
AU2009328499B2 (en) 2014-05-29
KR101308331B1 (ko) 2013-09-23
CA2734677A1 (en) 2010-06-24
MX2011006354A (es) 2011-07-13
US20140228440A1 (en) 2014-08-14
US20100197792A1 (en) 2010-08-05
TW201034658A (en) 2010-10-01
US8394857B2 (en) 2013-03-12
AU2009328499A1 (en) 2010-06-24
TWI432188B (zh) 2014-04-01
US20130150449A1 (en) 2013-06-13
JP5542835B2 (ja) 2014-07-09
JP2012509288A (ja) 2012-04-19
IL213606A0 (en) 2011-07-31
KR20110086173A (ko) 2011-07-27
WO2010069597A1 (en) 2010-06-24
RU2481828C2 (ru) 2013-05-20
CA2734677C (en) 2014-04-29

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