AR075160A1 - Derivados de aril y/o heteroaril piperidinas sustituidas, medicamentos que las contienen, proceso para prepararlas y uso de las mismas para el tratamiento de trastornos neurologicos y neuropsiquiatricos. - Google Patents
Derivados de aril y/o heteroaril piperidinas sustituidas, medicamentos que las contienen, proceso para prepararlas y uso de las mismas para el tratamiento de trastornos neurologicos y neuropsiquiatricos.Info
- Publication number
- AR075160A1 AR075160A1 ARP100100160A ARP100100160A AR075160A1 AR 075160 A1 AR075160 A1 AR 075160A1 AR P100100160 A ARP100100160 A AR P100100160A AR P100100160 A ARP100100160 A AR P100100160A AR 075160 A1 AR075160 A1 AR 075160A1
- Authority
- AR
- Argentina
- Prior art keywords
- lower alkyl
- halogen
- heteroaryl
- neurological
- treatment
- Prior art date
Links
- 230000000926 neurological effect Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 229910052736 halogen Inorganic materials 0.000 abstract 6
- 150000002367 halogens Chemical group 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000001072 heteroaryl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 4-aza-spiro [2,5] oct-6-yl Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
La presente se refiere a un compuesto de la formula general (1) en la que R1 es hidrogeno, alquilo inferior, CD3, -(CH2)n-CHO, -(CH2)n-O-alquilo inferior, -(CH2)n-OH, -(CH2)n-cicloalquilo o es heterocicloalquilo; R2 es hidrogeno, halogeno, hidroxi, alquilo inferior, dialquilo inferior, -OCH2-O-alquilo inferior o alcoxi inferior; o el anillo piperidina junto con R2 forma un anillo espiro, elegido entre 4-aza-espiro[2,5]oct-6-ilo; Ar es arilo o heteroarilo, que están opcionalmente sustituidos por uno, dos o tres sustituyentes elegidos entre halogeno, alquilo inferior, alquilo inferior sustituido por halogeno, alcoxi inferior sustituido por halogeno, cicloalquilo, alcoxi inferior, S-alquilo inferior, heteroarilo, heterocicloalquilo o por fenilo opcionalmente sustituido por R' y R' es halogeno, alquilo inferior, alcoxi inferior o alcoxi inferior sustituido por halogeno, o es heteroarilo; R es alquilo inferior, cicloalquilo, heterocicloalquilo, arilo o heteroarilo, dichos arilo y heteroarilo están opcionalmente sustituidos por uno o dos R'; n es el numero 0, 1, 2 o 3; o a una sal de adicion de ácido farmacéuticamente aceptable, a una mezcla racémica o a su enantiomero y/o isomero optico correspondiente. La presente se refiere además a composiciones farmacéuticas que contienen los compuestos de la formula (1) y a su utilizacion para el tratamiento de trastornos neurologicos y neuropsiquiátricos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09151382 | 2009-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR075160A1 true AR075160A1 (es) | 2011-03-16 |
Family
ID=41718529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100100160A AR075160A1 (es) | 2009-01-27 | 2010-01-26 | Derivados de aril y/o heteroaril piperidinas sustituidas, medicamentos que las contienen, proceso para prepararlas y uso de las mismas para el tratamiento de trastornos neurologicos y neuropsiquiatricos. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20100197715A1 (es) |
| EP (1) | EP2391603B1 (es) |
| JP (1) | JP5552494B2 (es) |
| KR (1) | KR101289577B1 (es) |
| CN (1) | CN102292320B (es) |
| AR (1) | AR075160A1 (es) |
| AU (1) | AU2010209816A1 (es) |
| BR (1) | BRPI1007410A2 (es) |
| CA (1) | CA2746967A1 (es) |
| CO (1) | CO6341621A2 (es) |
| CR (1) | CR20110348A (es) |
| EC (1) | ECSP11011196A (es) |
| ES (1) | ES2445143T3 (es) |
| IL (1) | IL213672A0 (es) |
| MA (1) | MA32947B1 (es) |
| MX (1) | MX2011007272A (es) |
| NZ (1) | NZ593279A (es) |
| PE (1) | PE20120500A1 (es) |
| RU (1) | RU2517701C2 (es) |
| SG (1) | SG173116A1 (es) |
| TW (1) | TWI403322B (es) |
| UA (1) | UA104611C2 (es) |
| WO (1) | WO2010086251A1 (es) |
| ZA (1) | ZA201104237B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102292320B (zh) | 2009-01-27 | 2014-07-02 | 弗·哈夫曼-拉罗切有限公司 | 作为glyt-1抑制剂的芳酰基氨基-和杂芳酰基氨基-取代的哌啶类 |
| US8658639B2 (en) * | 2009-06-24 | 2014-02-25 | Dainippon Sumitomo Pharma Co., Ltd | N-substituted-cyclic amino derivative |
| WO2013019621A1 (en) * | 2011-07-29 | 2013-02-07 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
| US9012489B2 (en) | 2011-08-03 | 2015-04-21 | Boehringer Ingelheim International Gmbh | Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament |
| US9023865B2 (en) | 2011-10-27 | 2015-05-05 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
| AU2020378084A1 (en) * | 2019-11-07 | 2022-05-26 | Chicago Biosolutions, Inc. | Inhibitors of influenza viral entry |
| CN114478360B (zh) * | 2022-02-10 | 2023-08-15 | 江苏海洋大学 | 一种苯甲酰胺类衍生物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2600557A1 (de) * | 1976-01-09 | 1977-07-14 | Delmar Chem | 4-aryl-3/4-amino/hydroxy-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| UA41251C2 (uk) * | 1990-01-04 | 2001-09-17 | Пфайзер, Інк. | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі |
| WO2001081308A2 (en) | 2000-04-20 | 2001-11-01 | Nps Allelix Corp. | Aminopiperidines for use as glyt-1 inhibitors |
| CA2443108A1 (en) * | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
| DK1594840T3 (da) * | 2003-02-17 | 2007-02-05 | Hoffmann La Roche | Piperidin-benzensulfonamid-derivater |
| FR2861074B1 (fr) * | 2003-10-17 | 2006-04-07 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| FR2861071B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique |
| JP4490434B2 (ja) | 2003-10-23 | 2010-06-23 | エフ．ホフマン−ラ ロシュ アーゲー | 神経及び神経精神疾患の処置においてＧｌｙＴ−１阻害剤として使用するためのトリアザ−スピロピペリジン誘導体 |
| EP2119702A4 (en) * | 2007-01-31 | 2010-12-08 | Dainippon Sumitomo Pharma Co | amide derivative |
| CN102292320B (zh) | 2009-01-27 | 2014-07-02 | 弗·哈夫曼-拉罗切有限公司 | 作为glyt-1抑制剂的芳酰基氨基-和杂芳酰基氨基-取代的哌啶类 |
-
2010
- 2010-01-19 CN CN201080005279.2A patent/CN102292320B/zh not_active Expired - Fee Related
- 2010-01-19 WO PCT/EP2010/050551 patent/WO2010086251A1/en not_active Ceased
- 2010-01-19 JP JP2011546772A patent/JP5552494B2/ja not_active Expired - Fee Related
- 2010-01-19 SG SG2011053360A patent/SG173116A1/en unknown
- 2010-01-19 UA UAA201110177A patent/UA104611C2/ru unknown
- 2010-01-19 BR BRPI1007410A patent/BRPI1007410A2/pt not_active Application Discontinuation
- 2010-01-19 ES ES10700563.9T patent/ES2445143T3/es active Active
- 2010-01-19 EP EP10700563.9A patent/EP2391603B1/en active Active
- 2010-01-19 MA MA33992A patent/MA32947B1/fr unknown
- 2010-01-19 CA CA2746967A patent/CA2746967A1/en not_active Abandoned
- 2010-01-19 MX MX2011007272A patent/MX2011007272A/es active IP Right Grant
- 2010-01-19 NZ NZ593279A patent/NZ593279A/xx not_active IP Right Cessation
- 2010-01-19 AU AU2010209816A patent/AU2010209816A1/en not_active Abandoned
- 2010-01-19 KR KR1020117019722A patent/KR101289577B1/ko not_active Expired - Fee Related
- 2010-01-19 RU RU2011134960/04A patent/RU2517701C2/ru not_active IP Right Cessation
- 2010-01-19 PE PE2011001308A patent/PE20120500A1/es not_active Application Discontinuation
- 2010-01-20 US US12/690,128 patent/US20100197715A1/en not_active Abandoned
- 2010-01-25 TW TW099101973A patent/TWI403322B/zh not_active IP Right Cessation
- 2010-01-26 AR ARP100100160A patent/AR075160A1/es not_active Application Discontinuation
-
2011
- 2011-06-07 ZA ZA2011/04237A patent/ZA201104237B/en unknown
- 2011-06-10 CO CO11072655A patent/CO6341621A2/es active IP Right Grant
- 2011-06-20 IL IL213672A patent/IL213672A0/en unknown
- 2011-06-21 CR CR20110348A patent/CR20110348A/es unknown
- 2011-07-11 EC EC2011011196A patent/ECSP11011196A/es unknown
-
2013
- 2013-02-14 US US13/766,840 patent/US9067911B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2746967A1 (en) | 2010-08-05 |
| MX2011007272A (es) | 2011-08-08 |
| EP2391603B1 (en) | 2014-01-08 |
| CO6341621A2 (es) | 2011-11-21 |
| RU2517701C2 (ru) | 2014-05-27 |
| EP2391603A1 (en) | 2011-12-07 |
| JP5552494B2 (ja) | 2014-07-16 |
| KR101289577B1 (ko) | 2013-07-24 |
| US20130158050A1 (en) | 2013-06-20 |
| PE20120500A1 (es) | 2012-05-04 |
| US9067911B2 (en) | 2015-06-30 |
| US20100197715A1 (en) | 2010-08-05 |
| TWI403322B (zh) | 2013-08-01 |
| CN102292320B (zh) | 2014-07-02 |
| CN102292320A (zh) | 2011-12-21 |
| SG173116A1 (en) | 2011-08-29 |
| ZA201104237B (en) | 2012-02-29 |
| NZ593279A (en) | 2013-03-28 |
| WO2010086251A1 (en) | 2010-08-05 |
| BRPI1007410A2 (pt) | 2016-02-16 |
| MA32947B1 (fr) | 2012-01-02 |
| JP2012515744A (ja) | 2012-07-12 |
| ES2445143T3 (es) | 2014-02-28 |
| CR20110348A (es) | 2011-09-06 |
| UA104611C2 (en) | 2014-02-25 |
| TW201032803A (en) | 2010-09-16 |
| ECSP11011196A (es) | 2011-08-31 |
| IL213672A0 (en) | 2011-07-31 |
| RU2011134960A (ru) | 2013-03-10 |
| AU2010209816A1 (en) | 2011-08-11 |
| KR20110107863A (ko) | 2011-10-04 |
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