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AR062009A1 - (s)-(-)-amlodipina camsilato o un hidrato del mismo y composiciones farmaceuticas que lo comprenden - Google Patents

(s)-(-)-amlodipina camsilato o un hidrato del mismo y composiciones farmaceuticas que lo comprenden

Info

Publication number
AR062009A1
AR062009A1 ARP070103244A ARP070103244A AR062009A1 AR 062009 A1 AR062009 A1 AR 062009A1 AR P070103244 A ARP070103244 A AR P070103244A AR P070103244 A ARP070103244 A AR P070103244A AR 062009 A1 AR062009 A1 AR 062009A1
Authority
AR
Argentina
Prior art keywords
camsilato
amlodipina
hydration
same
pharmaceutical compositions
Prior art date
Application number
ARP070103244A
Other languages
English (en)
Inventor
Lee Jaeheon
Sub Lee Moon
Ki Yang Weon
Yoo Jaeho
Lee Jae
Chul-Choi Chang
Kyong Ju-Kim Han
Chang Young
Kil-Lee Gwansun
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of AR062009A1 publication Critical patent/AR062009A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se refiere a (S)-(-)-amlodipina camsilato o un hidrato del mismo que tiene buena fotoestabilidad y buena solubilidad y a una composición farmacéutica que lo comprende, que puede usarse eficientemente para tratar enfermedades cardiovasculares. Reivindicación 2: El (S)-(-)-amlodipina camsilato de la reivindicación 1, caracterizado porque el ácido alcanforsulfónico es el ácido (1S)-(+)-10-alcanforsulfónico y el espectro de difracción de rayos X de su polvo muestra picos mayores a 2q de 4,8 ± 0,2; 10,0 ± 0,2; 11,0 ± 0,2; 13,8 ± 0,2; 14,3 ± 0,2; 16,4 ± 0,2; 18,2 ± 0,2; 18,8 ± 0,2; 19,8 ± 0,2; 20,0 ± 0,2; 20,5 ± 0,2 y 23,7 ± 0,2.
ARP070103244A 2006-07-21 2007-07-20 (s)-(-)-amlodipina camsilato o un hidrato del mismo y composiciones farmaceuticas que lo comprenden AR062009A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020060068401A KR100913791B1 (ko) 2006-07-21 2006-07-21 (ｓ)-(-)-암로디핀 캠실레이트 또는 이의 수화물 및 이를함유하는 약학적 조성물

Publications (1)

Publication Number Publication Date
AR062009A1 true AR062009A1 (es) 2008-08-10

Family

ID=38956963

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070103244A AR062009A1 (es) 2006-07-21 2007-07-20 (s)-(-)-amlodipina camsilato o un hidrato del mismo y composiciones farmaceuticas que lo comprenden

Country Status (19)

Country Link
US (1) US20090326234A1 (es)
EP (1) EP2044022A1 (es)
JP (1) JP2009544695A (es)
KR (1) KR100913791B1 (es)
CN (1) CN101495451B (es)
AR (1) AR062009A1 (es)
AU (1) AU2007276038B2 (es)
BR (1) BRPI0714313A2 (es)
CA (1) CA2658384C (es)
EC (1) ECSP089024A (es)
IL (1) IL196318A0 (es)
MX (1) MX2009000454A (es)
MY (1) MY152884A (es)
NO (1) NO20090819L (es)
NZ (1) NZ574006A (es)
RU (1) RU2403241C1 (es)
UA (1) UA93724C2 (es)
WO (1) WO2008010659A1 (es)
ZA (1) ZA200900231B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085014A1 (en) 2009-01-23 2010-07-29 Hanmi Pharm. Co., Ltd. Solid pharmaceutical composition comprising amlodipine and losartan and process for producing same
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
KR102521227B1 (ko) * 2018-09-12 2023-04-13 후지필름 가부시키가이샤 약액, 기판의 처리 방법
CN110882249B (zh) 2019-11-08 2021-04-30 北京吾为尔创科技有限公司 含苯磺酸左氨氯地平水合物的组合物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405833D0 (en) 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine
PL189666B1 (pl) * 1998-04-09 2005-09-30 Adamed Sp Z Oo Sposób otrzymywania benzenosulfonianu amlodypiny
KR100452491B1 (ko) * 2001-03-29 2004-10-12 한미약품 주식회사 신규한 결정형 암로디핀 캠실레이트 염 및 그의 제조방법
WO2002079518A1 (en) 2001-03-29 2002-10-10 Chugai Seiyaku Kabushiki Kaisha A method for genotyping individuals for multiple snps
CN1152013C (zh) * 2001-11-22 2004-06-02 张喜田 一类左旋氨氯地平盐的水合物及其制剂
KR20040011751A (ko) * 2002-07-30 2004-02-11 씨제이 주식회사 암로디핀의 유기산염
MXPA05007876A (es) * 2003-01-27 2005-09-21 Hanmi Pharm Ind Co Ltd Camsilato de amlodipino amorfo, estable, proceso para preparar el mismo y composicion para la administracion oral del mismo.
KR100841409B1 (ko) * 2003-12-16 2008-06-25 에스케이케미칼주식회사 암로디핀 겐티세이트 염과 이의 제조방법
ATE399154T1 (de) * 2004-10-20 2008-07-15 Emcure Pharmaceuticals Ltd Verfahren zur herstellung eines enantiomers von amlodipin in hoher optischer reinheit
GB0502509D0 (en) * 2005-02-07 2005-03-16 Pfizer Ltd Novel salt form of a dopamine agonist

Also Published As

Publication number Publication date
AU2007276038A1 (en) 2008-01-24
US20090326234A1 (en) 2009-12-31
CA2658384A1 (en) 2008-01-24
CN101495451B (zh) 2012-07-25
ECSP089024A (es) 2009-01-30
RU2009106073A (ru) 2010-08-27
CN101495451A (zh) 2009-07-29
JP2009544695A (ja) 2009-12-17
RU2403241C1 (ru) 2010-11-10
CA2658384C (en) 2012-01-17
ZA200900231B (en) 2010-04-28
BRPI0714313A2 (pt) 2013-04-02
NO20090819L (no) 2009-02-20
UA93724C2 (ru) 2011-03-10
KR100913791B1 (ko) 2009-08-26
IL196318A0 (en) 2009-09-22
MX2009000454A (es) 2009-01-28
AU2007276038B2 (en) 2011-06-16
KR20080008752A (ko) 2008-01-24
MY152884A (en) 2014-11-28
NZ574006A (en) 2010-09-30
WO2008010659A1 (en) 2008-01-24
EP2044022A1 (en) 2009-04-08

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