AR069411A1 - Metodo para identificacion de prolificidad en mamiferos, mediante el gen gdf-9 (factor 9 de crecimiento y diferenciacion) mutado, polipeptido codificado por dicho gen y equipo para deteccion e identificacion de animales superiores - Google Patents
Metodo para identificacion de prolificidad en mamiferos, mediante el gen gdf-9 (factor 9 de crecimiento y diferenciacion) mutado, polipeptido codificado por dicho gen y equipo para deteccion e identificacion de animales superioresInfo
- Publication number
- AR069411A1 AR069411A1 ARP080105081A ARP080105081A AR069411A1 AR 069411 A1 AR069411 A1 AR 069411A1 AR P080105081 A ARP080105081 A AR P080105081A AR P080105081 A ARP080105081 A AR P080105081A AR 069411 A1 AR069411 A1 AR 069411A1
- Authority
- AR
- Argentina
- Prior art keywords
- identification
- gen
- mammals
- animals
- gdf
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 241000124008 Mammalia Species 0.000 title abstract 3
- 108010076282 Factor IX Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 230000004069 differentiation Effects 0.000 title 1
- 230000012010 growth Effects 0.000 title 1
- 230000035772 mutation Effects 0.000 abstract 3
- 238000011835 investigation Methods 0.000 abstract 2
- 230000016087 ovulation Effects 0.000 abstract 2
- 230000002062 proliferating effect Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108090001086 Growth differentiation factor-9 Proteins 0.000 abstract 1
- 241001494479 Pecora Species 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 244000144980 herd Species 0.000 abstract 1
- 239000003999 initiator Substances 0.000 abstract 1
- 239000003147 molecular marker Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000001850 reproductive effect Effects 0.000 abstract 1
- 108091008146 restriction endonucleases Proteins 0.000 abstract 1
- 238000007619 statistical method Methods 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/124—Animal traits, i.e. production traits, including athletic performance or the like
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
Un método de prevision de prolificidad en mamíferos, por medio de análisis de marcador molecular específico para una mutacion correlacionada con el aumento de la tasa de ovulacion. La identificacion correcta y simple de la presencia de mutacion, proporcionada por el uso del método, puede ser de gran efectividad en el mejoramiento genético de ovinos, así como en el manejo reproductivo del rebano. La presente se refiere a una mutacion del gen GDF-9 que altera positivamente la tasa de ovulacion y al uso de dicha secuencia génica para la produccion de animales transgénicos de alta prolificidad. Reivindicacion 1: Método para identificacion de genotipos de alta prolificidad en mamíferos, caracterizado porque comprende: (a) extraer ácido nucleico (ADN genomico) de los animales bajo investigacion; (b) amplificar una region determinada del genoma, a partir de un par de iniciadores específicos, proxima al(los) gen(es) relacionado(s) con la fertilidad en animales; (c) digerir el fragmento obtenido en (b) con enzimas de restriccion; (d) analizar los productos amplificados; y (e) comparar los productos amplificados bajo investigacion para determinar su genotipo. (f) Aplicacion de métodos estadísticos adecuados para interpretacion de los resultados.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRC10706173-0A BRPI0706173C1 (pt) | 2007-11-23 | 2007-11-23 | metodo para identificação massal de animais com aumento na prolificidade |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069411A1 true AR069411A1 (es) | 2010-01-20 |
Family
ID=40667069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080105081A AR069411A1 (es) | 2007-11-23 | 2008-11-21 | Metodo para identificacion de prolificidad en mamiferos, mediante el gen gdf-9 (factor 9 de crecimiento y diferenciacion) mutado, polipeptido codificado por dicho gen y equipo para deteccion e identificacion de animales superiores |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110252489A1 (es) |
| EP (1) | EP2225395A4 (es) |
| AR (1) | AR069411A1 (es) |
| AU (1) | AU2008328475A1 (es) |
| BR (1) | BRPI0706173C1 (es) |
| UY (1) | UY31485A1 (es) |
| WO (1) | WO2009065204A1 (es) |
| ZA (1) | ZA201003669B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109504781A (zh) * | 2018-04-24 | 2019-03-22 | 内蒙古大学 | 一种提高苏尼特羊产羔数的单倍型遗传标记及其应用 |
| CN109402264B (zh) * | 2018-04-24 | 2022-10-21 | 内蒙古大学 | 一种提高苏尼特羊繁殖力的分子标记及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4650761A (en) * | 1981-11-27 | 1987-03-17 | Eli Lilly And Company | Method for stabilizing and selecting recombinant DNA containing host cell |
| NZ519330A (en) * | 2002-05-30 | 2004-12-24 | George Henry Davis | New sequences for altering mammalian ovarian function and ovulation rate |
| CN1274842C (zh) * | 2003-02-17 | 2006-09-13 | 中国农业科学院畜牧研究所 | 一种预测羊产羔数的方法及其应用 |
| JP2008521891A (ja) * | 2004-12-02 | 2008-06-26 | アグリサーチ・リミテッド | 排卵の調節 |
| WO2006097787A1 (en) * | 2005-03-16 | 2006-09-21 | University Of Guelph | Bovine cast gene snp and meat tenderness |
-
2007
- 2007-11-23 BR BRC10706173-0A patent/BRPI0706173C1/pt not_active Application Discontinuation
-
2008
- 2008-11-21 AR ARP080105081A patent/AR069411A1/es not_active Application Discontinuation
- 2008-11-24 US US12/744,288 patent/US20110252489A1/en not_active Abandoned
- 2008-11-24 UY UY31485A patent/UY31485A1/es unknown
- 2008-11-24 AU AU2008328475A patent/AU2008328475A1/en not_active Abandoned
- 2008-11-24 EP EP08852696A patent/EP2225395A4/en not_active Withdrawn
- 2008-11-24 WO PCT/BR2008/000356 patent/WO2009065204A1/en not_active Ceased
-
2010
- 2010-05-24 ZA ZA2010/03669A patent/ZA201003669B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY31485A1 (es) | 2009-07-17 |
| ZA201003669B (en) | 2012-01-25 |
| EP2225395A4 (en) | 2011-01-26 |
| WO2009065204A1 (en) | 2009-05-28 |
| US20110252489A1 (en) | 2011-10-13 |
| BRPI0706173A2 (pt) | 2009-07-28 |
| EP2225395A1 (en) | 2010-09-08 |
| AU2008328475A1 (en) | 2009-05-28 |
| BRPI0706173C1 (pt) | 2011-02-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109837347B (zh) | Catsper4基因第三外显子的snp作为猪精液品质性状的遗传标记 | |
| CN114250307B (zh) | 一种评价猪达100kg体重日龄的分子标记及其应用 | |
| CN101423872B (zh) | 荷斯坦牛抗热应激性育种的分子标记及其应用 | |
| Mucha et al. | Effect of EGF, AREG and LIF genes polymorphisms on reproductive traits in pigs | |
| CN119307626A (zh) | 一种猪产仔数性状相关的snp分子标记及其应用 | |
| CN103421797B (zh) | Sla-11基因作为猪产仔数性状的遗传标记 | |
| CN104651356A (zh) | 一种与二花脸母猪产仔性状相关的snp标记及其检测方法和应用 | |
| AR069411A1 (es) | Metodo para identificacion de prolificidad en mamiferos, mediante el gen gdf-9 (factor 9 de crecimiento y diferenciacion) mutado, polipeptido codificado por dicho gen y equipo para deteccion e identificacion de animales superiores | |
| AR045345A1 (es) | Uso de polimorfismo de nucleotidos individuales en la region de codificacion del receptor de leptina porcina para mejorar la produccion de porcinos | |
| CN114150068B (zh) | 一种与猪背膘厚相关的snp标记及其应用 | |
| Zhang et al. | Advances in genome-wide association studies for important traits in sheep and goats | |
| Herrera | Clinical applications of preimplantation genetic testing in equine, bovine, and human embryos | |
| CN105567816B (zh) | 猪8号染色体上与窝产仔数相关的snp位点 | |
| CN109182561B (zh) | Arhgap26作为牛超数排卵性状分子标记的应用 | |
| CN104651527A (zh) | 一种与二花脸母猪产仔性状相关的snp标记及其引物 | |
| CN104694651B (zh) | 一种与二花脸母猪产仔性状相关的snp标记、检测方法及应用 | |
| Wan et al. | A simple DNA extraction and rapid specific identification technique for single cells and early embryos of two breeds of Bos taurus | |
| CN104846080A (zh) | 一种与猪产仔数相关的cnv标记及其应用 | |
| Carneiro et al. | Sexing single bovine blastomeres using TSPY gene amplification | |
| CN103937805B (zh) | 一种与山羊抗寄生虫感染性状相关的分子标记及应用 | |
| CN119979726B (zh) | 猪精液品质性状关联的snp遗传标记及其应用 | |
| CN104726578B (zh) | 一种与二花脸母猪产仔性状相关的snp标记、检测方法及应用 | |
| Kumari et al. | Genetic polymorphism of bone morphogenetic protein receptor type 1 gene in Black Bengal goat and its association with litter size | |
| Choi et al. | Amplification of porcine SRY gene for sex determination | |
| CN103484457B (zh) | 利鲁牛微卫星分子标记引物对及其应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |