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AR066104A1 - Derivados de triazolopiridin - carboxamidas y triazolopirimidin-carboxamidas, su preparacion y su aplicacion en terapeutica - Google Patents

Derivados de triazolopiridin - carboxamidas y triazolopirimidin-carboxamidas, su preparacion y su aplicacion en terapeutica

Info

Publication number
AR066104A1
AR066104A1 ARP080101598A ARP080101598A AR066104A1 AR 066104 A1 AR066104 A1 AR 066104A1 AR P080101598 A ARP080101598 A AR P080101598A AR P080101598 A ARP080101598 A AR P080101598A AR 066104 A1 AR066104 A1 AR 066104A1
Authority
AR
Argentina
Prior art keywords
carboxamidas
derivatives
preparation
application
group
Prior art date
Application number
ARP080101598A
Other languages
English (en)
Inventor
Luc Even
Christian Hoornaert
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of AR066104A1 publication Critical patent/AR066104A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
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    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Neurology (AREA)
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  • Diabetes (AREA)
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  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

La presente se refiere a los derivados de triazolopiridin-carboxamidas y triazolopirimidin-carboxamidas, de formula general (1) en la que A y X representan, independientemente uno del otro, un átomo de nitrogeno o un grupo CH, R1 representa un grupoarilo o heteroarilo, opcionalmente sustituido con uno o varios grupos elegidos entre un átomo de halogeno, un grupo alquilo C1-6, haloalquiIo C1-6, alcoxi C1-6, haloalcoxi C1-6, R2 representa un grupo arilo, opcionalmente sustituido con uno o vanosgrupos elegidos entre un átomo de halogeno, un grupo metilo, trifluorometilo, metoxi, trifluorometoxi. Procedimiento de preparacion y aplicacion en terapéutica, para prevenir o tratar dolores agudos o cronicos, vértigo, vomitos, náuseas,dislipidemia, patologías neurologicas y psiquiátricas, neurodegenerativas, epilepsia, enfermedades cardiovasculares, cáncer, infecciones.
ARP080101598A 2007-04-18 2008-04-18 Derivados de triazolopiridin - carboxamidas y triazolopirimidin-carboxamidas, su preparacion y su aplicacion en terapeutica AR066104A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702808A FR2915198B1 (fr) 2007-04-18 2007-04-18 Derives de triazolopyridine-carboxamides et triazolopyridine -carboxamides, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
AR066104A1 true AR066104A1 (es) 2009-07-22

Family

ID=38776328

Family Applications (1)

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ARP080101598A AR066104A1 (es) 2007-04-18 2008-04-18 Derivados de triazolopiridin - carboxamidas y triazolopirimidin-carboxamidas, su preparacion y su aplicacion en terapeutica

Country Status (17)

Country Link
US (2) US7863279B2 (es)
EP (1) EP2146992A1 (es)
JP (1) JP2010524908A (es)
KR (1) KR20090130061A (es)
CN (1) CN101663304A (es)
AR (1) AR066104A1 (es)
AU (1) AU2008257324A1 (es)
BR (1) BRPI0810412A2 (es)
CA (1) CA2683936A1 (es)
CL (1) CL2008001103A1 (es)
FR (1) FR2915198B1 (es)
IL (1) IL201471A0 (es)
MX (1) MX2009011213A (es)
RU (1) RU2009142434A (es)
TW (1) TW200901992A (es)
UY (1) UY31037A1 (es)
WO (1) WO2008145843A1 (es)

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Also Published As

Publication number Publication date
FR2915198B1 (fr) 2009-12-18
CA2683936A1 (fr) 2008-12-04
RU2009142434A (ru) 2011-05-27
KR20090130061A (ko) 2009-12-17
IL201471A0 (en) 2010-05-31
AU2008257324A1 (en) 2008-12-04
US7863279B2 (en) 2011-01-04
US20100041670A1 (en) 2010-02-18
CN101663304A (zh) 2010-03-03
MX2009011213A (es) 2009-11-02
CL2008001103A1 (es) 2009-01-16
UY31037A1 (es) 2008-11-28
JP2010524908A (ja) 2010-07-22
TW200901992A (en) 2009-01-16
FR2915198A1 (fr) 2008-10-24
EP2146992A1 (fr) 2010-01-27
WO2008145843A1 (fr) 2008-12-04
US20110071162A1 (en) 2011-03-24
BRPI0810412A2 (pt) 2014-10-14

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