AR065286A1 - Composiciones y metodos que utilizan arn de interferencia destinado a genes de tipo mthfr para el control de nematodos - Google Patents
Composiciones y metodos que utilizan arn de interferencia destinado a genes de tipo mthfr para el control de nematodosInfo
- Publication number
- AR065286A1 AR065286A1 ARP080100570A ARP080100570A AR065286A1 AR 065286 A1 AR065286 A1 AR 065286A1 AR P080100570 A ARP080100570 A AR P080100570A AR P080100570 A ARP080100570 A AR P080100570A AR 065286 A1 AR065286 A1 AR 065286A1
- Authority
- AR
- Argentina
- Prior art keywords
- polynucleotide
- consecutive nucleotides
- sequence
- seq
- indicated
- Prior art date
Links
- 101000587058 Homo sapiens Methylenetetrahydrofolate reductase Proteins 0.000 title abstract 4
- 102100029684 Methylenetetrahydrofolate reductase Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000244206 Nematoda Species 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 15
- 102000040430 polynucleotide Human genes 0.000 abstract 15
- 239000002157 polynucleotide Substances 0.000 abstract 15
- 239000002773 nucleotide Substances 0.000 abstract 12
- 125000003729 nucleotide group Chemical group 0.000 abstract 12
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 3
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108700039887 Essential Genes Proteins 0.000 abstract 1
- 206010061217 Infestation Diseases 0.000 abstract 1
- 108700001094 Plant Genes Proteins 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Composiciones de ARN bicatenario y plantas transgénicas capaces de inhibir la expresion de genes esenciales para establecer o mantener en una planta la infestacion por nemátodos, y con métodos asociados con aquellas. Específicamente, el uso de ARN de interferencia para inhibir la expresion de un gen vegetal blanco, que es un gen de tipo MTHFR, y se relaciona con la generacion de plantas que tienen mayor resistencia a nemátodos parasitarios. Reivindicacion 1: Una molécula de dsARN caracterizada porque comprende i) una primera cadena que comprende una secuencia sustancialmente idéntica a una porcion de un gen de tipo MTHFR, y ii) una segunda cadena que comprende una secuencia sustancialmente complementaria de la primera cadena, en donde la porcion del gen de tipo MTHFR es de un polinucleotido seleccionado del grupo que consiste en: a) un polinucleotido que comprende una secuencia como se indica en SEQ ID N°: 1, 3, 7, 9, 11, 13, 15, 17 o 19; b) un polinucleotido que codifica un polipéptido que tiene una secuencia como se indica en SEQ ID N°: 2 ,8, 10, 12, 14, 16, 18, o 20; c) un polinucleotido que tiene al menos 70% de identidad de secuencia con un polinucleotido que tiene una secuencia como se indica en SEQ ID N°:1, 3, 7, 9, 11,13, 15, 17, o 19; d) un polinucleotido que codifica un polipéptido que tiene al menos 70% de identidad de secuencia con un polipéptido que tiene una secuencia como se indica en SEQ ID N°:2, 8, 10, 12, 14, 16, 18, o 20; e) un polinucleotido que comprende un fragmento de al menos 19 nucleotidos consecutivos, o al menos 50 nucleotidos consecutivos, o al menos 100 nucleotidos consecutivos, o al menos 200 nucleotidos consecutivos de un polinucleotido que tiene una secuencia como se indica en SEQ ID N°: 1, 3, 7, 9, 11, 13, 15, 17, o 19; f) un polinucleotido que comprende un fragmento que codifica una porcion biologicamente activa de un polipéptido que tiene una secuencia como se indica en SEQ ID N°: 2, 8, 10, 12, 14, 16, 18, o 20; g) un polinucleotido que se hibridiza en condiciones rigurosas a un polinucleotido que comprende al menos 19 nucleotidos consecutivos, o al menos 50 nucleotidos consecutivos, o al menos 100 nucleotidos consecutivos, o al menos 200 nucleotidos consecutivos de un polinucleotido que tiene una secuencia como se indica en SEQ ID N°: 1, 3, 7, 9, 11, 13, 15, 17, o 19; y h) un polinucleotido que se hibridiza en condiciones rigurosas a un polinucleotido que comprende al menos 19 nucleotidos consecutivos, o al menos 50 nucleotidos consecutivos, o al menos 100 nucleotidos consecutivos, o al menos 200 nucleotidos consecutivos de un polinucleotido que codifica un polipéptido que tiene una secuencia como se indica en SEQ ID N°: 2, 8, 10, 12, 14, 16, 18, o 20.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90062107P | 2007-02-09 | 2007-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR065286A1 true AR065286A1 (es) | 2009-05-27 |
Family
ID=39295979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080100570A AR065286A1 (es) | 2007-02-09 | 2008-02-08 | Composiciones y metodos que utilizan arn de interferencia destinado a genes de tipo mthfr para el control de nematodos |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100107276A1 (es) |
| EP (1) | EP2126094A1 (es) |
| CN (1) | CN101605904A (es) |
| AR (1) | AR065286A1 (es) |
| BR (1) | BRPI0806960A2 (es) |
| CA (1) | CA2676682A1 (es) |
| MX (1) | MX2009007772A (es) |
| WO (1) | WO2008095972A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012018108A2 (pt) | 2010-01-22 | 2015-10-20 | Bayer Ip Gmbh | combinações acaricidas e/ou inseticidas de ingredientes ativos |
| EP2460406A1 (en) | 2010-12-01 | 2012-06-06 | Bayer CropScience AG | Use of fluopyram for controlling nematodes in nematode resistant crops |
| CA2811694A1 (en) * | 2010-09-22 | 2012-03-29 | Bayer Intellectual Property Gmbh | Use of biological or chemical control agents for controlling insects and nematodes in resistant crops |
| UA109460C2 (uk) | 2010-11-02 | 2015-08-25 | Байєр Інтелекчуал Проперті Гмбх | N-гетарилметилпіразолілкарбоксаміди |
| MX2013005258A (es) | 2010-11-15 | 2013-07-05 | Bayer Ip Gmbh | N-aril pirazol(tio)carboxamidas. |
| US20130289077A1 (en) | 2010-12-29 | 2013-10-31 | Juergen Benting | Fungicide hydroximoyl-tetrazole derivatives |
| WO2012094529A2 (en) * | 2011-01-05 | 2012-07-12 | The Curators Of The University Of Missouri | Genes implicated in resistance to soybean cyst nematode infection and methods of their use |
| IN2014DN00156A (es) | 2011-08-10 | 2015-05-22 | Bayer Ip Gmbh | |
| CA2859467C (en) | 2011-12-19 | 2019-10-01 | Bayer Cropscience Ag | Use of anthranilic acid diamide derivatives for pest control in transgenic crops |
| US20130212741A1 (en) * | 2012-01-30 | 2013-08-15 | Iowa State University Research Foundation, Inc. | MOLECULAR CLONING OF BROWN-MIDRIB2 (bm2) GENE |
| EP2622961A1 (en) | 2012-02-02 | 2013-08-07 | Bayer CropScience AG | Acive compound combinations |
| TWI654180B (zh) | 2012-06-29 | 2019-03-21 | 美商艾佛艾姆希公司 | 殺真菌之雜環羧醯胺 |
| WO2014090765A1 (en) | 2012-12-12 | 2014-06-19 | Bayer Cropscience Ag | Use of 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-trifluoromethyl)-1 h-1,2,4 tfia zole for controlling nematodes in nematode-resistant crops |
| CN107849568B (zh) | 2015-08-07 | 2021-10-26 | 拜尔作物科学公司 | 根优先和胁迫诱导型启动子及其用途 |
| JP7148206B2 (ja) * | 2016-06-16 | 2022-10-05 | キージーン ナムローゼ フェンノートシャップ | 線虫抵抗性 |
| CN105925590B (zh) * | 2016-06-18 | 2019-05-17 | 北京大北农生物技术有限公司 | 除草剂抗性蛋白质、其编码基因及用途 |
| KR102273639B1 (ko) * | 2021-04-20 | 2021-07-06 | 씨제이제일제당 주식회사 | 신규한 이중기능성 메틸렌테트라히드로폴레이트 탈수소효소/메테닐테트라하이드로폴레이트 사이클로하이드롤라아제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1586645A3 (en) * | 1999-02-25 | 2006-02-22 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
| US20040031072A1 (en) * | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| US20070016976A1 (en) * | 2000-06-23 | 2007-01-18 | Fumiaki Katagiri | Plant genes involved in defense against pathogens |
| US7109033B2 (en) * | 2000-08-24 | 2006-09-19 | The Scripps Research Institute | Stress-regulated genes of plants, transgenic plants containing same, and methods of use |
| WO2003000898A1 (en) * | 2001-06-22 | 2003-01-03 | Syngenta Participations Ag | Plant genes involved in defense against pathogens |
-
2008
- 2008-02-07 CA CA002676682A patent/CA2676682A1/en not_active Abandoned
- 2008-02-07 WO PCT/EP2008/051484 patent/WO2008095972A1/en not_active Ceased
- 2008-02-07 MX MX2009007772A patent/MX2009007772A/es not_active Application Discontinuation
- 2008-02-07 EP EP08708769A patent/EP2126094A1/en not_active Withdrawn
- 2008-02-07 CN CNA200880004639XA patent/CN101605904A/zh active Pending
- 2008-02-07 BR BRPI0806960-3A2A patent/BRPI0806960A2/pt not_active IP Right Cessation
- 2008-02-07 US US12/524,584 patent/US20100107276A1/en not_active Abandoned
- 2008-02-08 AR ARP080100570A patent/AR065286A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0806960A2 (pt) | 2014-04-08 |
| EP2126094A1 (en) | 2009-12-02 |
| CA2676682A1 (en) | 2008-08-14 |
| WO2008095972A1 (en) | 2008-08-14 |
| CN101605904A (zh) | 2009-12-16 |
| MX2009007772A (es) | 2009-07-30 |
| US20100107276A1 (en) | 2010-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |