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AR052404A1 - Hidratos y polimorfos de 4-(((7r)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil)amino)-3- metoxi-n-(1-metil-4-piperidinil)-benzamida, procedimiento para su preparacion y su uso como farmaco - Google Patents

Hidratos y polimorfos de 4-(((7r)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil)amino)-3- metoxi-n-(1-metil-4-piperidinil)-benzamida, procedimiento para su preparacion y su uso como farmaco

Info

Publication number
AR052404A1
AR052404A1 ARP050103385A ARP050103385A AR052404A1 AR 052404 A1 AR052404 A1 AR 052404A1 AR P050103385 A ARP050103385 A AR P050103385A AR P050103385 A ARP050103385 A AR P050103385A AR 052404 A1 AR052404 A1 AR 052404A1
Authority
AR
Argentina
Prior art keywords
methyl
pteridinyl
benzamide
piperidinyl
tetrahydro
Prior art date
Application number
ARP050103385A
Other languages
English (en)
Inventor
Guenter Linz
Peter Sieger
Gerd F Kraemer
Rolf Herter
Matthias Hoffmann
Werner Rall
Rolf Schmid
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35311878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR052404(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR052404A1 publication Critical patent/AR052404A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente se refiere a hidratos y a polimorfos de la 4[[(7R)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil] amino]-3-metoxi-N-(1-metil-4-piperidinil)-benzamida, a un procedimiento para su preparacion y a su uso como fármaco. Reivindicacion 1: Hidratos del compuesto de Formula (1):
ARP050103385A 2004-08-14 2005-08-12 Hidratos y polimorfos de 4-(((7r)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil)amino)-3- metoxi-n-(1-metil-4-piperidinil)-benzamida, procedimiento para su preparacion y su uso como farmaco AR052404A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04019366 2004-08-14

Publications (1)

Publication Number Publication Date
AR052404A1 true AR052404A1 (es) 2007-03-21

Family

ID=35311878

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050103385A AR052404A1 (es) 2004-08-14 2005-08-12 Hidratos y polimorfos de 4-(((7r)-8-ciclopentil-7-etil-5,6,7,8-tetrahidro-5-metil-6-oxo-2-pteridinil)amino)-3- metoxi-n-(1-metil-4-piperidinil)-benzamida, procedimiento para su preparacion y su uso como farmaco

Country Status (19)

Country Link
US (3) US7728134B2 (es)
EP (1) EP1778691A1 (es)
JP (1) JP2008509953A (es)
KR (1) KR101221864B1 (es)
CN (1) CN101006090A (es)
AR (1) AR052404A1 (es)
AU (1) AU2005274340B2 (es)
BR (1) BRPI0514351A2 (es)
CA (1) CA2578098A1 (es)
EA (1) EA011407B1 (es)
EC (1) ECSP077249A (es)
IL (1) IL181302A0 (es)
MX (1) MX2007001854A (es)
NO (1) NO20070752L (es)
NZ (1) NZ553649A (es)
PE (1) PE20060424A1 (es)
TW (1) TWI370131B (es)
UA (1) UA87865C2 (es)
WO (1) WO2006018222A1 (es)

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US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
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JP2017504651A (ja) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド ジアゼパン誘導体の使用
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Also Published As

Publication number Publication date
TW200619220A (en) 2006-06-16
EA200700387A1 (ru) 2007-08-31
CA2578098A1 (en) 2006-02-23
TWI370131B (en) 2012-08-11
PE20060424A1 (es) 2006-06-09
US7728134B2 (en) 2010-06-01
AU2005274340B2 (en) 2012-04-05
WO2006018222A1 (de) 2006-02-23
EP1778691A1 (de) 2007-05-02
BRPI0514351A2 (pt) 2012-10-30
CN101006090A (zh) 2007-07-25
NZ553649A (en) 2010-11-26
US20090298840A1 (en) 2009-12-03
US20090318457A1 (en) 2009-12-24
WO2006018222A8 (de) 2006-06-15
NO20070752L (no) 2007-05-10
AU2005274340A1 (en) 2006-02-23
EA011407B1 (ru) 2009-02-27
KR20070050967A (ko) 2007-05-16
US8202867B2 (en) 2012-06-19
UA87865C2 (en) 2009-08-25
ECSP077249A (es) 2007-03-29
MX2007001854A (es) 2007-03-28
KR101221864B1 (ko) 2013-01-14
IL181302A0 (en) 2007-07-04
US8034816B2 (en) 2011-10-11
JP2008509953A (ja) 2008-04-03
US20060035902A1 (en) 2006-02-16

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