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UY30444A1 - Derivados de pirimidina, procesos para su preparacinn, composiciones farmaccuticos y usos de los mismos. - Google Patents

Derivados de pirimidina, procesos para su preparacinn, composiciones farmaccuticos y usos de los mismos.

Info

Publication number
UY30444A1
UY30444A1 UY30444A UY30444A UY30444A1 UY 30444 A1 UY30444 A1 UY 30444A1 UY 30444 A UY30444 A UY 30444A UY 30444 A UY30444 A UY 30444A UY 30444 A1 UY30444 A1 UY 30444A1
Authority
UY
Uruguay
Prior art keywords
pharmaccutic
compositions
processes
preparation
same
Prior art date
Application number
UY30444A
Other languages
English (en)
Inventor
David Buttar
David Rudge
Kevin Michael Foote
Thorsten Nowak
Theoclitou Marie-Elena
Thomas Andrew Peter
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY30444A1 publication Critical patent/UY30444A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se proporciona un compuesto de formula (I): proceso para la fabricacion del mismo, composiciones farmacéuticas del mismo y usos en terapias.
UY30444A 2006-06-30 2007-06-27 Derivados de pirimidina, procesos para su preparacinn, composiciones farmaccuticos y usos de los mismos. UY30444A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81825906P 2006-06-30 2006-06-30
US90842807P 2007-03-28 2007-03-28

Publications (1)

Publication Number Publication Date
UY30444A1 true UY30444A1 (es) 2008-01-31

Family

ID=38472858

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30444A UY30444A1 (es) 2006-06-30 2007-06-27 Derivados de pirimidina, procesos para su preparacinn, composiciones farmaccuticos y usos de los mismos.

Country Status (13)

Country Link
US (1) US20080004302A1 (es)
EP (1) EP2044063A1 (es)
JP (1) JP2009541480A (es)
KR (1) KR20090024270A (es)
AR (1) AR061737A1 (es)
AU (1) AU2007263655A1 (es)
CA (1) CA2654852A1 (es)
IL (1) IL195731A0 (es)
MX (1) MX2008016523A (es)
NO (1) NO20085217L (es)
TW (1) TW200817391A (es)
UY (1) UY30444A1 (es)
WO (1) WO2008001070A1 (es)

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UA99459C2 (en) * 2007-05-04 2012-08-27 Астразенека Аб 9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer
EP2166849A4 (en) * 2007-06-11 2010-09-15 Miikana Therapeutics Inc SUBSTITUTED PYRAZOL COMPOUNDS
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TW201006830A (en) * 2008-06-11 2010-02-16 Astrazeneca Ab Chemical compounds
WO2010005692A2 (en) * 2008-06-16 2010-01-14 E. I. Du Pont De Nemours And Company Insecticidal cyclic carbonyl amidines
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US8586581B2 (en) 2009-12-17 2013-11-19 Hoffmann-La Roche Inc Ethynyl compounds useful for treatment of CNS disorders
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ES2575688T3 (es) 2010-12-16 2016-06-30 Sumitomo Dainippon Pharma Co., Ltd. Derivado de imidazo[4,5-c]quinolin-1-ilo útil en terapia
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
CA2830129C (en) 2011-03-24 2016-07-19 Chemilia Ab Novel pyrimidine derivatives
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AU2013261267B2 (en) 2012-05-18 2017-06-29 Sumitomo Pharma Co., Ltd. Carboxylic acid compounds
CN107652289B (zh) 2012-06-13 2020-07-21 因塞特控股公司 作为fgfr抑制剂的取代的三环化合物
US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
JP6183053B2 (ja) * 2012-08-22 2017-08-23 宇部興産株式会社 テトラヒドロピラニルピリミジン化合物の製造方法
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
KR102269032B1 (ko) 2013-04-19 2021-06-24 인사이트 홀딩스 코포레이션 Fgfr 저해제로서 이환식 헤테로사이클
DK3186242T3 (da) 2014-08-29 2021-12-20 Tes Pharma S R L Alfa-amino-beta-carboxymuconsyre-semialdehyd-decarboxylasehæmmere
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
WO2016134294A1 (en) 2015-02-20 2016-08-25 Incyte Corporation Bicyclic heterocycles as fgfr4 inhibitors
PE20171514A1 (es) 2015-02-20 2017-10-20 Incyte Corp Heterociclos biciclicos como inhibidores de fgfr
PL3261639T3 (pl) * 2015-02-27 2022-12-19 Verseon International Corporation Podstawione związki pirazolowe jako inhibitory proteazy serynowej
CN109071529B (zh) 2016-04-28 2021-08-06 施万生物制药研发Ip有限责任公司 作为jak激酶抑制剂的嘧啶化合物
CN110381949B (zh) 2017-01-10 2023-12-08 财团法人卫生研究院 杂环化合物及其用途
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
MX2020004255A (es) 2017-10-27 2020-07-29 Theravance Biopharma R&D Ip Llc Compuesto de pirimidina como inhibidor de las janocinasas.
BR112020022373A2 (pt) 2018-05-04 2021-02-02 Incyte Corporation sais de um inibidor de fgfr
SG11202010636VA (en) 2018-05-04 2020-11-27 Incyte Corp Solid forms of an fgfr inhibitor and processes for preparing the same
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WO2020219639A1 (en) 2019-04-24 2020-10-29 Theravance Biopharma R&D Ip, Llc Ester and carbonate pyrimidine compounds as jak kinase inhibitors
TW202106681A (zh) 2019-04-24 2021-02-16 美商施萬生物製藥研發Ｉｐ有限責任公司 用於治療皮膚疾病之嘧啶jak抑制劑
CN110143939A (zh) * 2019-05-07 2019-08-20 中国科学技术大学 一种由呋喃醛基化合物制备呋喃丙烯酸酯的方法
WO2021007269A1 (en) 2019-07-09 2021-01-14 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
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CN115151539A (zh) 2019-12-04 2022-10-04 因赛特公司 Fgfr抑制剂的衍生物
WO2021115560A1 (en) * 2019-12-09 2021-06-17 Rottapharm Biotech S.R.L. New fyn and vegfr2 kinase inhibitors
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US12065494B2 (en) 2021-04-12 2024-08-20 Incyte Corporation Combination therapy comprising an FGFR inhibitor and a Nectin-4 targeting agent
AR126102A1 (es) 2021-06-09 2023-09-13 Incyte Corp Heterociclos tricíclicos como inhibidores de fgfr
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IL317674A (en) 2022-05-26 2025-02-01 Tes Pharma S R L PYRIMIDINONE COMPOUNDS FOR THE TREATMENT OF ACUTE INFLAMMATION
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US6613776B2 (en) * 2000-09-15 2003-09-02 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6610677B2 (en) * 2000-09-15 2003-08-26 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) * 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
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Also Published As

Publication number Publication date
CA2654852A1 (en) 2008-01-03
MX2008016523A (es) 2009-01-19
NO20085217L (no) 2009-01-12
TW200817391A (en) 2008-04-16
US20080004302A1 (en) 2008-01-03
IL195731A0 (en) 2009-09-01
WO2008001070A1 (en) 2008-01-03
KR20090024270A (ko) 2009-03-06
AR061737A1 (es) 2008-09-17
AU2007263655A1 (en) 2008-01-03
EP2044063A1 (en) 2009-04-08
JP2009541480A (ja) 2009-11-26

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Legal Events

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Effective date: 20120606