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AR057451A1 - Metodos para preparar derivados de acido glutamico - Google Patents

Metodos para preparar derivados de acido glutamico

Info

Publication number
AR057451A1
AR057451A1 ARP060102975A ARP060102975A AR057451A1 AR 057451 A1 AR057451 A1 AR 057451A1 AR P060102975 A ARP060102975 A AR P060102975A AR P060102975 A ARP060102975 A AR P060102975A AR 057451 A1 AR057451 A1 AR 057451A1
Authority
AR
Argentina
Prior art keywords
methods
glutamic acid
alkyl
formula
prepare derivatives
Prior art date
Application number
ARP060102975A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR057451A1 publication Critical patent/AR057451A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Reivindicacion 1: Método para preparar un compuesto de la formula (4) caracterizado porque R2 es H, alquilo C1-6, alquenilo C2-6, alquinilo C2-6, (CH2)nR11, -OH, u -O-alquilo C1-6; R11 es arilo, heteroarilo o cicloalquilo; n es 0, 1, 2, 3, o 4; R16 es alquilo C1-6; PG1 es un grupo protector de amina; y PG2 es un grupo protector de ácido carboxílico, que comprende tratar un compuesto de la formula (2) donde R2, PG1 y PG2 son como se definen en este documento anteriormente, con un alquilcloroformiato de la formula (3) y una base, donde R16 es como se define en este documento anteriormente.
ARP060102975A 2005-10-13 2006-07-11 Metodos para preparar derivados de acido glutamico AR057451A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72644105P 2005-10-13 2005-10-13

Publications (1)

Publication Number Publication Date
AR057451A1 true AR057451A1 (es) 2007-12-05

Family

ID=37119907

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060102975A AR057451A1 (es) 2005-10-13 2006-07-11 Metodos para preparar derivados de acido glutamico

Country Status (18)

Country Link
US (1) US7541485B2 (es)
EP (1) EP1934171A1 (es)
JP (1) JP2009511578A (es)
KR (1) KR20080058436A (es)
CN (1) CN101282927A (es)
AR (1) AR057451A1 (es)
AU (1) AU2006299918A1 (es)
BR (1) BRPI0617348A2 (es)
CA (1) CA2624866A1 (es)
CR (1) CR9885A (es)
EC (1) ECSP088360A (es)
GT (1) GT200600305A (es)
IL (1) IL190729A0 (es)
NO (1) NO20081617L (es)
PE (1) PE20070526A1 (es)
RU (1) RU2008113222A (es)
TW (1) TW200740729A (es)
WO (1) WO2007044100A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR061420A1 (es) * 2006-06-02 2008-08-27 Wyeth Corp Metodos para preparar derivados de acido glutamico e intermediarios del mismo
US20100216886A1 (en) * 2006-11-09 2010-08-26 Wyeth Polymorphs of n2-(1,1'-biphenyl-4-ylcarbonyl)-n1-[2-(4-fluorophenyl)-1,1-dimethylethyl]-l-alpha-glutamine
ES2776106T3 (es) * 2011-09-30 2020-07-29 Kemira Oyj Prevención de la degradación de almidón en procesos fabricación de pulpa, papel o cartón
US10266488B2 (en) 2013-10-10 2019-04-23 Eastern Virginia Medical School 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase
WO2016172496A1 (en) 2015-04-23 2016-10-27 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and uses thereof
TWI753037B (zh) 2016-10-26 2022-01-21 美商星座製藥公司 Lsd1抑制劑及其用途
JP2024508794A (ja) 2021-02-19 2024-02-28 スドー バイオサイエンシーズ リミテッド Ｔｙｋ２阻害剤およびその使用
CA3207819A1 (en) 2021-02-19 2022-08-25 Anjali Pandey Tyk2 inhibitors and uses thereof

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Also Published As

Publication number Publication date
IL190729A0 (en) 2008-11-03
EP1934171A1 (en) 2008-06-25
NO20081617L (no) 2008-05-06
KR20080058436A (ko) 2008-06-25
CN101282927A (zh) 2008-10-08
BRPI0617348A2 (pt) 2011-07-26
CR9885A (es) 2008-06-16
RU2008113222A (ru) 2009-11-20
CA2624866A1 (en) 2007-04-19
TW200740729A (en) 2007-11-01
US7541485B2 (en) 2009-06-02
GT200600305A (es) 2007-02-26
WO2007044100A1 (en) 2007-04-19
PE20070526A1 (es) 2007-06-11
AU2006299918A1 (en) 2007-04-19
ECSP088360A (es) 2008-05-30
US20070088172A1 (en) 2007-04-19
JP2009511578A (ja) 2009-03-19

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