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AR056994A1 - Proceso para preparar isatinas con control de formacion de subproductos - Google Patents

Proceso para preparar isatinas con control de formacion de subproductos

Info

Publication number
AR056994A1
AR056994A1 ARP060101693A ARP060101693A AR056994A1 AR 056994 A1 AR056994 A1 AR 056994A1 AR P060101693 A ARP060101693 A AR P060101693A AR P060101693 A ARP060101693 A AR P060101693A AR 056994 A1 AR056994 A1 AR 056994A1
Authority
AR
Argentina
Prior art keywords
isatin
isatinas
subproduct
prepare
formation
Prior art date
Application number
ARP060101693A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR056994A1 publication Critical patent/AR056994A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Se proporcionan métodos y kits para prevenir o reducir al mínimo la formacion de oximas de isatina durante la formacion de una isatina a partir de una isonitrosoacetanilida. También se proporcionan métodos y kits para prevenir o reducir al mínimo la formacion de impurezas de oximas de isatina después de la formacion de una isatina a partir de una isonitrosoacetanilida utilizando un agente senuelo en los pasos de templado y/o extraccion. Las isatinas pueden prepararse utilizando un agente senuelo y deseablemente un ácido fuerte. Se proporcionan además métodos para preparar oximas de isatina.
ARP060101693A 2005-04-29 2006-04-27 Proceso para preparar isatinas con control de formacion de subproductos AR056994A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67614905P 2005-04-29 2005-04-29

Publications (1)

Publication Number Publication Date
AR056994A1 true AR056994A1 (es) 2007-11-07

Family

ID=36928870

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060101693A AR056994A1 (es) 2005-04-29 2006-04-27 Proceso para preparar isatinas con control de formacion de subproductos

Country Status (6)

Country Link
US (1) US20060247442A1 (es)
AR (1) AR056994A1 (es)
GT (1) GT200600180A (es)
PE (1) PE20061413A1 (es)
TW (1) TW200716611A (es)
WO (1) WO2006119104A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20070220A1 (es) * 2005-07-29 2007-03-19 Wyeth Corp Proceso para la sintesis de moduladores del receptor de progesterona

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2346938A1 (de) * 1973-09-18 1975-04-10 Bayer Ag Verfahren zur herstellung von isatinen
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives
FR2530633A1 (fr) * 1982-06-03 1984-01-27 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, et les compositions les renfermant
GB2208511A (en) * 1987-08-07 1989-04-05 Bayer Ag Variants of bovine pancreatic trypsin inhibitor produced by recombinant dna technology
ATE318815T1 (de) * 2002-08-22 2006-03-15 Neurosearch As Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten

Also Published As

Publication number Publication date
TW200716611A (en) 2007-05-01
PE20061413A1 (es) 2007-01-20
US20060247442A1 (en) 2006-11-02
GT200600180A (es) 2006-11-22
WO2006119104A2 (en) 2006-11-09
WO2006119104A3 (en) 2007-03-01

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal