AR049929A1 - Metodos y composiciones para el tratamiento de afecciones oftalmicas con derivados de retinilo - Google Patents
Metodos y composiciones para el tratamiento de afecciones oftalmicas con derivados de retiniloInfo
- Publication number
- AR049929A1 AR049929A1 ARP050102545A ARP050102545A AR049929A1 AR 049929 A1 AR049929 A1 AR 049929A1 AR P050102545 A ARP050102545 A AR P050102545A AR P050102545 A ARP050102545 A AR P050102545A AR 049929 A1 AR049929 A1 AR 049929A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- methods
- derivatives
- ophthaltic
- affections
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/164—Retinal disorders, e.g. retinopathy
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Los compuestos que producen ceguera nocturna reversible pueden usarse para tratar condiciones oftálmicas asociadas con la sobreproduccion de productos de desecho que se acumulan durante el curso del ciclo visual. Se decriben métodos y composiciones que usan tales compuestos y sus derivados para tratar, entre otras, las degeneraciones y distrofias maculares o para aliviar síntomas asociados con tales condiciones oftálmicas. Los compuestos y sus derivados pueden usarse como agentes de una terapia unica o en combinacion con otros agentes o terapias.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58229304P | 2004-06-23 | 2004-06-23 | |
| US62969504P | 2004-11-19 | 2004-11-19 | |
| US66090405P | 2005-03-11 | 2005-03-11 | |
| US67240505P | 2005-04-18 | 2005-04-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR049929A1 true AR049929A1 (es) | 2006-09-13 |
Family
ID=34981643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050102545A AR049929A1 (es) | 2004-06-23 | 2005-06-21 | Metodos y composiciones para el tratamiento de afecciones oftalmicas con derivados de retinilo |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US8314152B2 (es) |
| EP (3) | EP2025336A1 (es) |
| JP (1) | JP4855396B2 (es) |
| KR (1) | KR100862930B1 (es) |
| AR (1) | AR049929A1 (es) |
| AT (1) | ATE404188T1 (es) |
| AU (1) | AU2005262558B8 (es) |
| BR (1) | BRPI0512569A (es) |
| CA (1) | CA2569691C (es) |
| CY (1) | CY1110435T1 (es) |
| DE (1) | DE602005008970D1 (es) |
| DK (1) | DK1768657T3 (es) |
| EA (1) | EA011864B1 (es) |
| ES (1) | ES2313368T3 (es) |
| GE (1) | GEP20084520B (es) |
| IL (1) | IL179872A (es) |
| LV (1) | LV13564B (es) |
| MX (1) | MXPA06014978A (es) |
| NO (1) | NO20070408L (es) |
| NZ (1) | NZ551955A (es) |
| PL (1) | PL1768657T3 (es) |
| PT (1) | PT1768657E (es) |
| SG (1) | SG140607A1 (es) |
| SI (1) | SI1768657T1 (es) |
| TW (1) | TWI396532B (es) |
| WO (1) | WO2006007314A1 (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2324823A3 (en) | 2003-03-14 | 2011-11-16 | University of Washington | Retinoid replacements and opsin agonists and methods for the use thereof |
| KR20060135819A (ko) | 2004-02-17 | 2006-12-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 황반변성을 포함하는 안과질환의 관리 |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| JP2007525496A (ja) * | 2004-02-17 | 2007-09-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 黄班変性症を含む眼科疾患の管理 |
| LT2397133T (lt) | 2004-06-18 | 2018-01-10 | University Of Washington | Tinklainei skirti dariniai ir būdai, skirti naudoti regėjimo susirgimų gydymui |
| CA2569691C (en) | 2004-06-23 | 2010-08-17 | Sirion Therapeutics, Inc. | Methods and compositions for treating ophthalmic conditions with retinyl derivatives |
| US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| WO2006033734A2 (en) * | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| CA2580363A1 (en) * | 2004-10-28 | 2006-05-11 | Idexx Laboratories, Inc. | Compositions for controlled delivery of pharmaceutically active compounds |
| WO2006052860A2 (en) * | 2004-11-04 | 2006-05-18 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (rbp)-transthyretin (ttr) complex formation |
| AU2005314039B2 (en) * | 2004-12-08 | 2008-01-31 | Revision Therapeutics, Inc. | Methods, assays and compositions for treating retinol-related diseases |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| US8114440B2 (en) * | 2005-11-16 | 2012-02-14 | Idexx Laboratories Inc. | Pharmaceutical compositions for the administration of aptamers |
| US7754679B2 (en) * | 2005-11-16 | 2010-07-13 | Idexx Laboratories, Inc. | Pharmaceutical compositions for the administration of aptamers |
| CA2655036A1 (en) * | 2006-06-22 | 2007-12-27 | Sirion Therapeutics, Inc. | Methods and compositions for treating ophthalmic conditions via modulation of megalin activity |
| CA2657238A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic disease |
| CA2657164A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions and methods for treating or preventing ophthalmic light toxicity |
| WO2008013983A2 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Opsin stabilizing compounds and methods of use |
| US8828960B2 (en) * | 2007-07-17 | 2014-09-09 | Idexx Laboratories, Inc. | Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds |
| KR20160092032A (ko) | 2008-02-11 | 2016-08-03 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 연령-관련 망막 기능장애의 치료 및 예방 방법 |
| WO2009114136A2 (en) * | 2008-03-12 | 2009-09-17 | Albert Einstein College Of Medicine Of Yeshiva University | Fenretinide derivatives and uses thereof as therapeutic, diagnostic and imaging agents |
| MX2011000545A (es) * | 2008-07-14 | 2011-02-24 | Otonomy Inc | Composiciones de liberacion controlada para la modulacion de apoptosis y metodos para el tratamiento de trastornos oticos. |
| ES2549916T3 (es) * | 2009-05-04 | 2015-11-03 | Acucela, Inc. | Composiciones para usar en el tratamiento de glaucoma o hipertensión ocular |
| IN2012DN00352A (es) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
| WO2011034551A2 (en) | 2009-09-15 | 2011-03-24 | Qlt Inc. | Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle |
| JP5815552B2 (ja) | 2009-12-08 | 2015-11-17 | ケース ウェスタン リザーブ ユニバーシティCase Westernreserve University | 眼疾患を治療する化合物および方法 |
| KR20180043846A (ko) | 2010-04-19 | 2018-04-30 | 노벨리언 테라퓨틱스 인코포레이티드 | 내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료 요법 및 방법 |
| US9353063B2 (en) | 2011-11-30 | 2016-05-31 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
| PT2797601T (pt) * | 2012-02-10 | 2018-06-27 | Taiwan Liposome Co Ltd | Composições farmacêuticas para reduzir complicações de esteroide ocular |
| CA2865935C (en) | 2012-03-01 | 2021-12-14 | Qlt Inc. | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
| WO2014003850A2 (en) | 2012-06-26 | 2014-01-03 | Timothy Paul Foster | Methods for treatment of ocular diseases |
| US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
| US10471118B2 (en) * | 2014-05-30 | 2019-11-12 | Case Western Reserve University | Retinylamine derivitives for treatment of ocular disorders |
| CR20170160A (es) | 2014-10-24 | 2017-06-15 | Takeda Pharmaceuticals Co | Compuesto heterocíclico |
| CN107249678B (zh) * | 2014-12-19 | 2021-02-19 | 凯敏工业公司 | 使用离子电渗法进行生物活性分子的眼内递送 |
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| EP3416622B1 (en) * | 2016-02-15 | 2023-06-28 | Kemin Industries, Inc. | Positively charged liposomes as lipophilic molecule carriers |
| US11395853B2 (en) * | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
| EP3547899A2 (en) * | 2016-12-05 | 2019-10-09 | The Jackson Laboratory | Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans |
| US11931327B2 (en) | 2017-07-04 | 2024-03-19 | Daiichi Sankyo Company, Limited | Drug for retinal degenerative disease associated with photoreceptor degeneration |
| MX2021013609A (es) * | 2019-05-06 | 2022-04-06 | Univ California | Materiales y métodos para tratar la degeneración macular relacionada con la edad. |
| FR3105790B1 (fr) * | 2019-12-26 | 2022-01-14 | Biophytis | Composés chimiques ciblant l’œil et leur utilisation dans le traitement de maladies oculaires |
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| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
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| LT2397133T (lt) | 2004-06-18 | 2018-01-10 | University Of Washington | Tinklainei skirti dariniai ir būdai, skirti naudoti regėjimo susirgimų gydymui |
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| UA81382C2 (en) | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding |
-
2005
- 2005-06-06 CA CA2569691A patent/CA2569691C/en not_active Expired - Fee Related
- 2005-06-06 PL PL05758777T patent/PL1768657T3/pl unknown
- 2005-06-06 EP EP08014275A patent/EP2025336A1/en not_active Withdrawn
- 2005-06-06 PT PT05758777T patent/PT1768657E/pt unknown
- 2005-06-06 ES ES05758777T patent/ES2313368T3/es not_active Expired - Lifetime
- 2005-06-06 EA EA200700109A patent/EA011864B1/ru not_active IP Right Cessation
- 2005-06-06 EP EP10181656A patent/EP2277516A1/en not_active Withdrawn
- 2005-06-06 SI SI200530415T patent/SI1768657T1/sl unknown
- 2005-06-06 NZ NZ551955A patent/NZ551955A/en not_active IP Right Cessation
- 2005-06-06 GE GEAP20059816A patent/GEP20084520B/en unknown
- 2005-06-06 DK DK05758777T patent/DK1768657T3/da active
- 2005-06-06 AT AT05758777T patent/ATE404188T1/de active
- 2005-06-06 AU AU2005262558A patent/AU2005262558B8/en not_active Ceased
- 2005-06-06 JP JP2007518098A patent/JP4855396B2/ja not_active Expired - Fee Related
- 2005-06-06 SG SG200801546-3A patent/SG140607A1/en unknown
- 2005-06-06 EP EP05758777A patent/EP1768657B1/en not_active Expired - Lifetime
- 2005-06-06 WO PCT/US2005/020080 patent/WO2006007314A1/en not_active Ceased
- 2005-06-06 BR BRPI0512569-3A patent/BRPI0512569A/pt not_active IP Right Cessation
- 2005-06-06 MX MXPA06014978A patent/MXPA06014978A/es active IP Right Grant
- 2005-06-06 DE DE602005008970T patent/DE602005008970D1/de not_active Expired - Lifetime
- 2005-06-06 KR KR1020077001270A patent/KR100862930B1/ko not_active Expired - Fee Related
- 2005-06-10 US US11/150,641 patent/US8314152B2/en not_active Expired - Fee Related
- 2005-06-21 AR ARP050102545A patent/AR049929A1/es not_active Application Discontinuation
- 2005-06-22 TW TW094120880A patent/TWI396532B/zh not_active IP Right Cessation
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2006
- 2006-12-06 IL IL179872A patent/IL179872A/en not_active IP Right Cessation
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2007
- 2007-01-19 LV LVP-07-05A patent/LV13564B/lv unknown
- 2007-01-22 NO NO20070408A patent/NO20070408L/no not_active Application Discontinuation
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2008
- 2008-11-12 CY CY20081101287T patent/CY1110435T1/el unknown
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2010
- 2010-04-21 US US12/764,764 patent/US8410168B2/en not_active Expired - Fee Related
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2011
- 2011-05-27 US US13/118,330 patent/US20110294891A1/en not_active Abandoned
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