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AR047949A1 - Preparacion farmaceutica que comprende un anticuerpo contra el receptor de factor de crecimiento endotelial - Google Patents

Preparacion farmaceutica que comprende un anticuerpo contra el receptor de factor de crecimiento endotelial

Info

Publication number
AR047949A1
AR047949A1 ARP040104380A ARP040104380A AR047949A1 AR 047949 A1 AR047949 A1 AR 047949A1 AR P040104380 A ARP040104380 A AR P040104380A AR P040104380 A ARP040104380 A AR P040104380A AR 047949 A1 AR047949 A1 AR 047949A1
Authority
AR
Argentina
Prior art keywords
growth factor
antibody against
pharmaceutical preparation
factor receiver
understanding
Prior art date
Application number
ARP040104380A
Other languages
English (en)
Inventor
Hanns-Christian Mahler
Robert Mueller
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34609304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR047949(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR047949A1 publication Critical patent/AR047949A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Preparacion farmacéutica acuosa que contiene un anticuerpo contra el receptor de factor de crecimiento endotelial (receptor EGF) un buffer, un aminoácido y un tensioactivo. La preparacion es estable en el almacenamiento, incluso a temperaturas elevadas, y se puede usar para el tratamiento de tumores.
ARP040104380A 2003-11-26 2004-11-26 Preparacion farmaceutica que comprende un anticuerpo contra el receptor de factor de crecimiento endotelial AR047949A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10355251A DE10355251A1 (de) 2003-11-26 2003-11-26 Pharmazeutische Zubereitung enthaltend einen Antikörper gegen den EGF-Rezeptor

Publications (1)

Publication Number Publication Date
AR047949A1 true AR047949A1 (es) 2006-03-15

Family

ID=34609304

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104380A AR047949A1 (es) 2003-11-26 2004-11-26 Preparacion farmaceutica que comprende un anticuerpo contra el receptor de factor de crecimiento endotelial

Country Status (30)

Country Link
US (2) US20050175611A1 (es)
EP (1) EP1687031B1 (es)
JP (1) JP2007512266A (es)
KR (1) KR20060110305A (es)
CN (1) CN1886158B (es)
AR (1) AR047949A1 (es)
AT (1) ATE457740T1 (es)
AU (1) AU2004298728B2 (es)
BR (1) BRPI0416986A (es)
CA (1) CA2547060A1 (es)
CO (1) CO5690620A2 (es)
CY (1) CY1110344T1 (es)
DE (2) DE10355251A1 (es)
DK (1) DK1687031T3 (es)
EC (1) ECSP066662A (es)
ES (1) ES2339671T3 (es)
IL (1) IL175727A0 (es)
MX (1) MXPA06005901A (es)
MY (1) MY145214A (es)
NZ (1) NZ548129A (es)
PE (1) PE20050586A1 (es)
PL (1) PL1687031T3 (es)
PT (1) PT1687031E (es)
RU (1) RU2381036C2 (es)
SG (1) SG150550A1 (es)
SI (1) SI1687031T1 (es)
TW (1) TWI322693B (es)
UA (1) UA90460C2 (es)
WO (1) WO2005058365A1 (es)
ZA (1) ZA200605219B (es)

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Also Published As

Publication number Publication date
UA90460C2 (ru) 2010-05-11
RU2006122638A (ru) 2008-01-10
DK1687031T3 (da) 2010-05-31
EP1687031A1 (de) 2006-08-09
AU2004298728B2 (en) 2010-09-16
TW200531702A (en) 2005-10-01
PT1687031E (pt) 2010-05-21
PE20050586A1 (es) 2005-08-15
SI1687031T1 (sl) 2010-04-30
CN1886158A (zh) 2006-12-27
ATE457740T1 (de) 2010-03-15
CN1886158B (zh) 2011-09-07
ZA200605219B (en) 2007-04-25
CO5690620A2 (es) 2006-10-31
WO2005058365A1 (de) 2005-06-30
CY1110344T1 (el) 2015-01-14
ECSP066662A (es) 2006-10-25
HK1095534A1 (en) 2007-05-11
PL1687031T3 (pl) 2010-06-30
TWI322693B (en) 2010-04-01
CA2547060A1 (en) 2005-06-30
NZ548129A (en) 2010-09-30
US20050175611A1 (en) 2005-08-11
EP1687031B1 (de) 2010-02-17
SG150550A1 (en) 2009-03-30
BRPI0416986A (pt) 2007-02-06
AU2004298728A1 (en) 2005-06-30
US20110177068A1 (en) 2011-07-21
JP2007512266A (ja) 2007-05-17
DE502004010783D1 (de) 2010-04-01
MY145214A (en) 2012-01-13
RU2381036C2 (ru) 2010-02-10
ES2339671T3 (es) 2010-05-24
DE10355251A1 (de) 2005-06-23
IL175727A0 (en) 2006-09-05
KR20060110305A (ko) 2006-10-24
MXPA06005901A (es) 2006-06-27

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