AR032876A1 - Compuestos de carbamato para utilizar en la prevencion o tratamiento de los trastornos psicoticos - Google Patents
Compuestos de carbamato para utilizar en la prevencion o tratamiento de los trastornos psicoticosInfo
- Publication number
- AR032876A1 AR032876A1 ARP020100702A ARP020100702A AR032876A1 AR 032876 A1 AR032876 A1 AR 032876A1 AR P020100702 A ARP020100702 A AR P020100702A AR P020100702 A ARP020100702 A AR P020100702A AR 032876 A1 AR032876 A1 AR 032876A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- psychotic disorders
- phenyl
- alkyl
- prevention
- Prior art date
Links
- 208000028017 Psychotic disease Diseases 0.000 title abstract 2
- 150000004657 carbamic acid derivatives Chemical class 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente hace referencia a un método para prevenir o tratar trastornos psicoticos que comprende la administracion a un paciente que lo necesita de una cantidad terapéuticamente eficaz de un compuesto seleccionado del grupo formado por las formulas (1) y (2). Donde fenilo se sustituye en X con uno a cinco átomos de halogeno seleccionados del grupo compuesto por fluor, bromo, y yodo; R1, R2, R3, R4, R5 y R6 son independientemente seleccionados del grupo compuesto por hidrogeno y alquilo de C1-4; donde el alquilo de C1-4 es opcionalmente sustituido con fenilo (en el cual el fenilo es opcionalmente sustituido con sustituyentes independientemente seleccionado del grupo compuesto por halogeno, alquilo de C1-4, alcoxi de C1-4, amino, nitro y ciano).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27188901P | 2001-02-27 | 2001-02-27 | |
| US10/081,761 US6541513B2 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating psychotic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR032876A1 true AR032876A1 (es) | 2003-11-26 |
Family
ID=26765939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020100702A AR032876A1 (es) | 2001-02-27 | 2002-02-27 | Compuestos de carbamato para utilizar en la prevencion o tratamiento de los trastornos psicoticos |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6541513B2 (es) |
| EP (1) | EP1401424B1 (es) |
| JP (1) | JP4276841B2 (es) |
| KR (1) | KR100886578B1 (es) |
| CN (1) | CN1262271C (es) |
| AR (1) | AR032876A1 (es) |
| AT (1) | ATE346597T1 (es) |
| AU (1) | AU2002242296B2 (es) |
| BR (1) | BR0207829A (es) |
| CA (1) | CA2439480C (es) |
| CZ (1) | CZ302412B6 (es) |
| DE (1) | DE60216457T2 (es) |
| DK (1) | DK1401424T3 (es) |
| ES (1) | ES2275844T3 (es) |
| HU (1) | HUP0303342A3 (es) |
| IL (2) | IL157588A0 (es) |
| MX (1) | MXPA03007722A (es) |
| NO (1) | NO20033801L (es) |
| NZ (1) | NZ527991A (es) |
| PL (1) | PL365021A1 (es) |
| PT (1) | PT1401424E (es) |
| RS (1) | RS51056B (es) |
| RU (1) | RU2302240C2 (es) |
| TW (1) | TWI251486B (es) |
| WO (1) | WO2002067927A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1305082E (pt) * | 2000-07-21 | 2004-09-30 | Ortho Mcneil Pharm Inc | Compostos de carbamato para utilizacao na prevencao ou tratamento da dor neuropatica e dor associada a cefaleia de salvas e enxaqueca |
| ES2262826T3 (es) * | 2001-02-27 | 2006-12-01 | Ortho-Mcneil Pharmaceutical, Inc. | Uso de un compuesto de carbamato en la prevencion o el tratamiento de transtornos de ansiedad. |
| RS51055B (sr) * | 2001-02-27 | 2010-10-31 | Ortho-Mcneil Pharmaceutical Inc. | Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju neurodegenerativnih poremećaja |
| CN1259911C (zh) | 2001-07-16 | 2006-06-21 | 奥索-麦克尼尔药品公司 | 用于预防或治疗神经性疼痛和丛集性头痛及偏头痛性疼痛的氨基甲酸酯化合物 |
| EP1744750A2 (en) * | 2004-05-06 | 2007-01-24 | Sandoz AG | Pharmaceutical composition comprising hydrophobic drug having improved solubility |
| BRPI0520451A2 (pt) * | 2005-07-26 | 2009-05-12 | Janssen Pharmaceutica Nv | métodos para tratamento de distúrbios associados a substáncias quìmicas |
| JP2010508355A (ja) * | 2006-10-30 | 2010-03-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 鬱病を処置する方法 |
| EA200970435A1 (ru) * | 2006-10-31 | 2009-10-30 | Янссен Фармацевтика, Н. В. | Лечение общих расстройств развития |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| WO2014142477A1 (en) | 2013-03-12 | 2014-09-18 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy and epilesy-related syndromes |
| CN105164103B (zh) * | 2013-03-12 | 2019-12-06 | 比皮艾思药物研发有限公司 | 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物 |
| KR102900173B1 (ko) * | 2016-12-14 | 2025-12-12 | 에스케이바이오팜 주식회사 | 조현병, 강박장애 및 투렛증후군으로부터 선택되는 정신증 장애의 예방, 경감 또는 치료에 있어서의 카바메이트 화합물의 용도 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US278380A (en) * | 1883-05-29 | Thermometer | ||
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| JP2955358B2 (ja) * | 1989-06-09 | 1999-10-04 | ファルマシア・アンド・アップジョン・カンパニー | 中枢神経系活性を有する複素環系アミン |
| US5492930A (en) * | 1994-04-25 | 1996-02-20 | Schering Corporation | Method and formulation for treating CNS disorders |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
-
2002
- 2002-02-21 EP EP02707927A patent/EP1401424B1/en not_active Expired - Lifetime
- 2002-02-21 JP JP2002567294A patent/JP4276841B2/ja not_active Expired - Lifetime
- 2002-02-21 CZ CZ20032297A patent/CZ302412B6/cs not_active IP Right Cessation
- 2002-02-21 PL PL02365021A patent/PL365021A1/xx unknown
- 2002-02-21 ES ES02707927T patent/ES2275844T3/es not_active Expired - Lifetime
- 2002-02-21 CN CNB028089235A patent/CN1262271C/zh not_active Expired - Fee Related
- 2002-02-21 IL IL15758802A patent/IL157588A0/xx unknown
- 2002-02-21 RU RU2003128983/14A patent/RU2302240C2/ru active
- 2002-02-21 AT AT02707927T patent/ATE346597T1/de active
- 2002-02-21 RS YUP-675/03A patent/RS51056B/sr unknown
- 2002-02-21 AU AU2002242296A patent/AU2002242296B2/en not_active Ceased
- 2002-02-21 NZ NZ527991A patent/NZ527991A/en unknown
- 2002-02-21 WO PCT/US2002/006119 patent/WO2002067927A1/en not_active Ceased
- 2002-02-21 BR BR0207829-5A patent/BR0207829A/pt not_active Application Discontinuation
- 2002-02-21 DK DK02707927T patent/DK1401424T3/da active
- 2002-02-21 KR KR1020037011292A patent/KR100886578B1/ko not_active Expired - Lifetime
- 2002-02-21 PT PT02707927T patent/PT1401424E/pt unknown
- 2002-02-21 US US10/081,761 patent/US6541513B2/en not_active Expired - Lifetime
- 2002-02-21 MX MXPA03007722A patent/MXPA03007722A/es active IP Right Grant
- 2002-02-21 CA CA2439480A patent/CA2439480C/en not_active Expired - Fee Related
- 2002-02-21 DE DE60216457T patent/DE60216457T2/de not_active Expired - Lifetime
- 2002-02-21 HU HU0303342A patent/HUP0303342A3/hu unknown
- 2002-02-27 AR ARP020100702A patent/AR032876A1/es unknown
- 2002-03-05 TW TW091103972A patent/TWI251486B/zh not_active IP Right Cessation
-
2003
- 2003-08-26 IL IL157588A patent/IL157588A/en not_active IP Right Cessation
- 2003-08-26 NO NO20033801A patent/NO20033801L/no not_active Application Discontinuation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |