AR039938A1 - Fitasas modificadas - Google Patents
Fitasas modificadasInfo
- Publication number
- AR039938A1 AR039938A1 ARP030101936A ARP030101936A AR039938A1 AR 039938 A1 AR039938 A1 AR 039938A1 AR P030101936 A ARP030101936 A AR P030101936A AR P030101936 A ARP030101936 A AR P030101936A AR 039938 A1 AR039938 A1 AR 039938A1
- Authority
- AR
- Argentina
- Prior art keywords
- phytase
- modified
- phytases
- model
- compared
- Prior art date
Links
- 108010011619 6-Phytase Proteins 0.000 abstract 12
- 229940085127 phytase Drugs 0.000 abstract 8
- 241000228245 Aspergillus niger Species 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000000717 retained effect Effects 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente describe fitasas modificadas. Estas fitasas están modificadas en comparación con una fitasa modelo en diversas posiciones, en particular para incrementar la termoestabilidad de la fitasa modificada en comparación con la de la fitasa modelo. Las fitasas modificadas han retenido otras propiedades favorables de la fitasa de Aspergillus niger, en particular porque en la fitasa modificada se han retenido residuos de aminoácidos específicos de la fitasa de Aspergillus niger. Polinucleótidos que codifican para dichas fitasas, vector, célula huésped, procedimientos para la producción de los polipéptidos y composición que los comprende. Reivindicación 1: Un polipéptido, caracterizado porque cuando se alinea con una fitasa modelo está ,modificado en comparación con dicha fitasa modelo en al menos una de las siguientes posiciones: 5, 6, 13, 19, 21, 29, 31, 36, 39, 43, 53, 69, 78, 81, 85, 87, 99, 112, 113, 122, 125, 126, 128,137,147, 148, 157,160, 163, 165, 169, 172, 176, 178, 180, 181, 182, 183, 189, 194, 197, 201, 203, 211, 213, 215, 218, 222, 223, 225, 232, 233, 242, 246, 247, 248, 249, 250, 251, 252, 254, 269, 291, 296, 310, 312, 315, 322, 330, 342, 346, 362, 365, 367, 368, 372, 374, 375, 382, 384, 395, 414, 417, 425, 428, 438, 440.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02100608 | 2002-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR039938A1 true AR039938A1 (es) | 2005-03-09 |
Family
ID=29595046
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101936A AR039938A1 (es) | 2002-05-30 | 2003-05-30 | Fitasas modificadas |
| ARP030101937A AR039939A1 (es) | 2002-05-30 | 2003-05-30 | Fitasas modificadas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101937A AR039939A1 (es) | 2002-05-30 | 2003-05-30 | Fitasas modificadas |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1513931A2 (es) |
| JP (1) | JP2005533492A (es) |
| KR (1) | KR20050038593A (es) |
| CN (1) | CN1656217A (es) |
| AR (2) | AR039938A1 (es) |
| AU (1) | AU2003238448A1 (es) |
| BR (1) | BR0311287A (es) |
| CA (1) | CA2485513A1 (es) |
| MX (1) | MXPA04011224A (es) |
| NO (1) | NO20044802L (es) |
| PE (1) | PE20040537A1 (es) |
| PL (1) | PL372824A1 (es) |
| RU (1) | RU2329301C2 (es) |
| TW (2) | TW200401033A (es) |
| WO (1) | WO2003102174A2 (es) |
| ZA (1) | ZA200410369B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0422052D0 (en) * | 2004-10-04 | 2004-11-03 | Dansico As | Enzymes |
| WO2007112739A1 (en) | 2006-04-04 | 2007-10-11 | Novozymes A/S | Phytase variants |
| DE102006053059A1 (de) * | 2006-11-10 | 2008-05-15 | Ab Enzymes Gmbh | Polypeptid mit Phytaseaktivität und erhöhter Temperaturstabilität der Enzymaktivität sowie dieses codierende Nukleotidsequenz |
| CN102854158B (zh) * | 2011-07-01 | 2016-01-20 | 北京昕大洋科技发展有限公司 | 一种快速测定植酸酶耐温性能的方法 |
| CN105441406A (zh) * | 2014-08-05 | 2016-03-30 | 北京大学 | 植酸酶变体 |
| CN108251439B (zh) * | 2018-01-11 | 2021-03-30 | 山西大学 | 一种人工改造的耐胰蛋白酶的植酸酶及其制备方法和应用 |
| CN117683745A (zh) * | 2020-04-29 | 2024-03-12 | 南京百斯杰生物工程有限公司 | 一种亲本植酸酶变体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2316082A (en) * | 1996-08-13 | 1998-02-18 | Finnfeeds Int Ltd | Phytase |
| EP1151088B1 (en) * | 1999-01-22 | 2006-08-30 | Novozymes A/S | Improved phytases |
-
2003
- 2003-05-28 AU AU2003238448A patent/AU2003238448A1/en not_active Abandoned
- 2003-05-28 CA CA002485513A patent/CA2485513A1/en not_active Abandoned
- 2003-05-28 BR BR0311287-0A patent/BR0311287A/pt not_active IP Right Cessation
- 2003-05-28 PL PL03372824A patent/PL372824A1/xx not_active Application Discontinuation
- 2003-05-28 WO PCT/EP2003/005729 patent/WO2003102174A2/en not_active Ceased
- 2003-05-28 JP JP2004510416A patent/JP2005533492A/ja not_active Withdrawn
- 2003-05-28 EP EP03732516A patent/EP1513931A2/en not_active Withdrawn
- 2003-05-28 MX MXPA04011224A patent/MXPA04011224A/es not_active Application Discontinuation
- 2003-05-28 RU RU2004139054/13A patent/RU2329301C2/ru not_active IP Right Cessation
- 2003-05-28 CN CNA03812470XA patent/CN1656217A/zh active Pending
- 2003-05-28 KR KR1020047019401A patent/KR20050038593A/ko not_active Withdrawn
- 2003-05-30 AR ARP030101936A patent/AR039938A1/es not_active Application Discontinuation
- 2003-05-30 TW TW092114745A patent/TW200401033A/zh unknown
- 2003-05-30 PE PE2003000534A patent/PE20040537A1/es not_active Application Discontinuation
- 2003-05-30 TW TW092114788A patent/TW200403341A/zh unknown
- 2003-05-30 AR ARP030101937A patent/AR039939A1/es not_active Application Discontinuation
-
2004
- 2004-11-04 NO NO20044802A patent/NO20044802L/no not_active Application Discontinuation
- 2004-12-23 ZA ZA200410369A patent/ZA200410369B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1513931A2 (en) | 2005-03-16 |
| BR0311287A (pt) | 2005-03-29 |
| WO2003102174A2 (en) | 2003-12-11 |
| MXPA04011224A (es) | 2005-01-25 |
| KR20050038593A (ko) | 2005-04-27 |
| JP2005533492A (ja) | 2005-11-10 |
| RU2329301C2 (ru) | 2008-07-20 |
| ZA200410369B (en) | 2006-06-28 |
| CN1656217A (zh) | 2005-08-17 |
| PL372824A1 (en) | 2005-08-08 |
| AR039939A1 (es) | 2005-03-09 |
| TW200401033A (en) | 2004-01-16 |
| CA2485513A1 (en) | 2003-12-11 |
| NO20044802L (no) | 2004-12-08 |
| RU2004139054A (ru) | 2005-06-27 |
| AU2003238448A1 (en) | 2003-12-19 |
| TW200403341A (en) | 2004-03-01 |
| WO2003102174A3 (en) | 2004-03-25 |
| PE20040537A1 (es) | 2004-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal | ||
| FB | Suspension of granting procedure |