AR038236A1 - COMPRESSED NELFINAVIR OF INCREASED DOSE AND METHOD TO MANUFACTURE IT - Google Patents
COMPRESSED NELFINAVIR OF INCREASED DOSE AND METHOD TO MANUFACTURE ITInfo
- Publication number
- AR038236A1 AR038236A1 ARP030100228A ARP030100228A AR038236A1 AR 038236 A1 AR038236 A1 AR 038236A1 AR P030100228 A ARP030100228 A AR P030100228A AR P030100228 A ARP030100228 A AR P030100228A AR 038236 A1 AR038236 A1 AR 038236A1
- Authority
- AR
- Argentina
- Prior art keywords
- nelfinavir
- compressed
- manufacture
- increased dose
- mixture
- Prior art date
Links
- QAGYKUNXZHXKMR-UHFFFAOYSA-N CPD000469186 Natural products CC1=C(O)C=CC=C1C(=O)NC(C(O)CN1C(CC2CCCCC2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-UHFFFAOYSA-N 0.000 title abstract 5
- 229960000884 nelfinavir Drugs 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- QAGYKUNXZHXKMR-HKWSIXNMSA-N nelfinavir Chemical compound CC1=C(O)C=CC=C1C(=O)N[C@H]([C@H](O)CN1[C@@H](C[C@@H]2CCCC[C@@H]2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-HKWSIXNMSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 239000011230 binding agent Substances 0.000 abstract 2
- 238000005469 granulation Methods 0.000 abstract 2
- 230000003179 granulation Effects 0.000 abstract 2
- -1 nelfinavir compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glanulating (AREA)
Abstract
Un comprimido de nelfinavir de dosis elevada que tiene una relación en peso de nelfinavir a aglutinante de aproximadamente 3:1 a aproximadamente 5:1. Los comprimidos de nelfinavir de dosis elevada se fabrican en un procedimiento en el que se forma una mezcla granulada de un compuesto de nelfinavir y un aglutinante, en un procedimiento de granulación, y a continuación se elabora para formar los comprimidos. En el procedimiento de granulación se anade humedad y se aplica energía mecánica a la mezcla, y la mezcla se cura sin adición de humedad o aplicación de energía mecánica.A high dose nelfinavir tablet having a weight ratio of nelfinavir to binder of about 3: 1 to about 5: 1. High-dose nelfinavir tablets are manufactured in a process in which a granulated mixture of a nelfinavir compound and a binder is formed, in a granulation process, and then processed to form the tablets. In the granulation process moisture is added and mechanical energy is applied to the mixture, and the mixture is cured without addition of moisture or application of mechanical energy.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35142002P | 2002-01-28 | 2002-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR038236A1 true AR038236A1 (en) | 2005-01-05 |
Family
ID=27663002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030100228A AR038236A1 (en) | 2002-01-28 | 2003-01-27 | COMPRESSED NELFINAVIR OF INCREASED DOSE AND METHOD TO MANUFACTURE IT |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1469836A1 (en) |
| JP (1) | JP2005521661A (en) |
| KR (1) | KR20040079952A (en) |
| CN (1) | CN1713895A (en) |
| AR (1) | AR038236A1 (en) |
| BR (1) | BR0307190A (en) |
| CA (1) | CA2398226A1 (en) |
| GT (1) | GT200300016A (en) |
| HN (1) | HN2003000048A (en) |
| HU (1) | HUP0500512A2 (en) |
| IL (1) | IL162724A0 (en) |
| MX (1) | MXPA04007237A (en) |
| NI (1) | NI200300001A (en) |
| NO (1) | NO20043238L (en) |
| NZ (1) | NZ533283A (en) |
| PA (1) | PA8564301A1 (en) |
| PE (1) | PE20030730A1 (en) |
| PL (1) | PL373882A1 (en) |
| RU (1) | RU2004123206A (en) |
| SV (1) | SV2004001467A (en) |
| TW (1) | TW200302111A (en) |
| WO (1) | WO2003063837A1 (en) |
| ZA (1) | ZA200404367B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008053276A1 (en) * | 2006-10-30 | 2008-05-08 | Collette Nv | Transition piece for the transfer of powder or granular material from a discharge opening to a conveying line and method of transferring powder or granular material |
| AU2007358602A1 (en) * | 2007-09-03 | 2009-03-12 | Lucent Technologies Inc. | Method and system for checking automatically connectivity status of an IP link on IP network |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6499984B1 (en) * | 2000-05-22 | 2002-12-31 | Warner-Lambert Company | Continuous production of pharmaceutical granulation |
| MXPA03009971A (en) * | 2001-05-03 | 2004-02-12 | Hoffmann La Roche | Pharmaceutical dosage form of amorphous nelfinavir mesylate. |
-
2002
- 2002-08-15 CA CA002398226A patent/CA2398226A1/en not_active Abandoned
-
2003
- 2003-01-07 NI NI200300001A patent/NI200300001A/en unknown
- 2003-01-16 NZ NZ533283A patent/NZ533283A/en unknown
- 2003-01-16 WO PCT/IB2003/000117 patent/WO2003063837A1/en not_active Ceased
- 2003-01-16 EP EP03700070A patent/EP1469836A1/en not_active Withdrawn
- 2003-01-16 BR BR0307190-1A patent/BR0307190A/en not_active IP Right Cessation
- 2003-01-16 MX MXPA04007237A patent/MXPA04007237A/en unknown
- 2003-01-16 HU HU0500512A patent/HUP0500512A2/en unknown
- 2003-01-16 RU RU2004123206/15A patent/RU2004123206A/en not_active Application Discontinuation
- 2003-01-16 KR KR10-2004-7011562A patent/KR20040079952A/en not_active Ceased
- 2003-01-16 JP JP2003563531A patent/JP2005521661A/en active Pending
- 2003-01-16 CN CNA038028360A patent/CN1713895A/en active Pending
- 2003-01-16 PL PL03373882A patent/PL373882A1/en not_active Application Discontinuation
- 2003-01-16 IL IL16272403A patent/IL162724A0/en unknown
- 2003-01-24 PE PE2003000074A patent/PE20030730A1/en not_active Application Discontinuation
- 2003-01-27 AR ARP030100228A patent/AR038236A1/en unknown
- 2003-01-27 SV SV2003001467A patent/SV2004001467A/en not_active Application Discontinuation
- 2003-01-27 TW TW092101739A patent/TW200302111A/en unknown
- 2003-01-27 HN HN2003000048A patent/HN2003000048A/en unknown
- 2003-01-28 GT GT200300016A patent/GT200300016A/en unknown
- 2003-01-28 PA PA20038564301A patent/PA8564301A1/en unknown
-
2004
- 2004-06-03 ZA ZA200404367A patent/ZA200404367B/en unknown
- 2004-08-02 NO NO20043238A patent/NO20043238L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20043238L (en) | 2004-08-02 |
| CA2398226A1 (en) | 2003-07-28 |
| RU2004123206A (en) | 2005-04-20 |
| PA8564301A1 (en) | 2003-09-05 |
| GT200300016A (en) | 2003-09-11 |
| HUP0500512A2 (en) | 2005-09-28 |
| NI200300001A (en) | 2004-12-21 |
| HN2003000048A (en) | 2003-10-28 |
| KR20040079952A (en) | 2004-09-16 |
| WO2003063837A1 (en) | 2003-08-07 |
| CN1713895A (en) | 2005-12-28 |
| IL162724A0 (en) | 2005-11-20 |
| BR0307190A (en) | 2004-11-03 |
| JP2005521661A (en) | 2005-07-21 |
| PL373882A1 (en) | 2005-09-19 |
| MXPA04007237A (en) | 2004-10-29 |
| NZ533283A (en) | 2006-12-22 |
| ZA200404367B (en) | 2006-05-31 |
| TW200302111A (en) | 2003-08-01 |
| EP1469836A1 (en) | 2004-10-27 |
| SV2004001467A (en) | 2004-05-07 |
| PE20030730A1 (en) | 2003-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |