AR034037A1 - Inhibidor de aromatasa en dosis multiples para tratar la infertilidad - Google Patents
Inhibidor de aromatasa en dosis multiples para tratar la infertilidadInfo
- Publication number
- AR034037A1 AR034037A1 ARP020101400A ARP020101400A AR034037A1 AR 034037 A1 AR034037 A1 AR 034037A1 AR P020101400 A ARP020101400 A AR P020101400A AR P020101400 A ARP020101400 A AR P020101400A AR 034037 A1 AR034037 A1 AR 034037A1
- Authority
- AR
- Argentina
- Prior art keywords
- daily doses
- aromatase inhibitor
- hormone
- administering
- folliculostimulant
- Prior art date
Links
- 229940122815 Aromatase inhibitor Drugs 0.000 title abstract 7
- 239000003886 aromatase inhibitor Substances 0.000 title abstract 7
- 208000000509 infertility Diseases 0.000 title abstract 4
- 230000036512 infertility Effects 0.000 title abstract 4
- 231100000535 infertility Toxicity 0.000 title abstract 4
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 abstract 4
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 abstract 4
- 229940028334 follicle stimulating hormone Drugs 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 229940088597 hormone Drugs 0.000 abstract 3
- 239000005556 hormone Substances 0.000 abstract 3
- 230000002513 anti-ovulatory effect Effects 0.000 abstract 2
- 230000016087 ovulation Effects 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000027758 ovulation cycle Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un método para inducir la ovulación de un sujeto de sexo femenino que sufre de infertilidad anovulatoria que comprende administrar a dicho sujeto dos o más dosis diarias de al menos un inhibidor de aromatasa. Un método para aumentar la ovulación en un sujeto de sexo femenino que sufre de infertilidad sin causa aparente u otro tipo de infertilidad anovulatoria que comprende administrar a dicho sujeto de sexo femenino una combinación de dos o más dosis diarias de al menos un inhibidor de aromatasa en uno o más ciclos menstruales. Un método para reducir sustancialmente los niveles de dosificación de hormona folículostimulante (FSH) para administrar a una mujer que comprende administrar una combinación de dos o más dosis diarias de por lo menos un inhibidor de aromatasa (AI) con varias dosis diarias de hormona foliculostimulante (FSH). Un método para aumentar la respuesta a la hormona foliculostimulante de una mujer que tiene un bajo nivel de respuesta a la estimulación del folículo, que comprende administrar una combinación de dos o más dosis diarias de por lo menos un inhibidor de aromatasa (AI) con varias dosis diarias de hormona foliculostimulante (FSH). También se incluyen preparaciones farmacéuticas y usos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CA2001/000517 WO2002083146A1 (en) | 2001-04-17 | 2001-04-17 | Multiple dose aromatase inhibitor for treating infertility |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR034037A1 true AR034037A1 (es) | 2004-01-21 |
Family
ID=4143137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020101400A AR034037A1 (es) | 2001-04-17 | 2002-04-17 | Inhibidor de aromatasa en dosis multiples para tratar la infertilidad |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7820706B2 (es) |
| AR (1) | AR034037A1 (es) |
| BR (1) | BR0208955A (es) |
| CA (1) | CA2472309C (es) |
| MX (1) | MXPA03009448A (es) |
| WO (2) | WO2002083146A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004087211A2 (en) | 2003-04-01 | 2004-10-14 | Applied Research Systems Ars Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| WO2007056851A1 (en) * | 2005-11-17 | 2007-05-24 | Mount Sinai Hospital | Compositions and methods for enhancing ovulation inducing agents |
| US20100087407A1 (en) * | 2006-08-04 | 2010-04-08 | James Symons | use of aromatase inhibitors |
| WO2011143752A1 (en) * | 2010-05-20 | 2011-11-24 | University Of Saskatchewan | Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal |
| WO2014169395A1 (en) | 2013-04-19 | 2014-10-23 | University Of Saskatchewan | Aromatase inhibitor-releasing intravaginal device |
| RU2527166C1 (ru) * | 2013-07-26 | 2014-08-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО РостГМУ Минздрава России) | Способ моделирования синдрома хронической ановуляции |
| EP3582799A1 (en) * | 2017-02-17 | 2019-12-25 | Celmatix Inc. | Methods for assessing the probability of achieving ongoing pregnancy and informing treatment therefrom |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845227A (en) * | 1984-06-18 | 1989-07-04 | Eli Lilly And Company | Aromatase inhibitors from azoles |
| DE4330237C2 (de) * | 1993-09-02 | 1995-11-30 | Schering Ag | 1-Methylsubstituierte Androsta-1,4-dien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
| DE4330023C2 (de) | 1993-09-06 | 2001-11-29 | Koenig & Bauer Ag | Vorrichtung zum Klemmen und Spannen einer biegsamen Druckplatte |
| DE19622457A1 (de) * | 1996-05-24 | 1997-11-27 | Schering Ag | 7alpha-(5-Methylaminopentyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha-(5-Methylaminopentyl)-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln |
| US6953774B2 (en) * | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
-
2001
- 2001-04-17 WO PCT/CA2001/000517 patent/WO2002083146A1/en not_active Ceased
- 2001-04-17 US US10/475,175 patent/US7820706B2/en not_active Expired - Fee Related
- 2001-04-17 CA CA2472309A patent/CA2472309C/en not_active Expired - Fee Related
-
2002
- 2002-04-17 BR BR0208955-6A patent/BR0208955A/pt not_active IP Right Cessation
- 2002-04-17 AR ARP020101400A patent/AR034037A1/es unknown
- 2002-04-17 WO PCT/CA2002/000520 patent/WO2002083239A1/en not_active Ceased
- 2002-04-17 MX MXPA03009448A patent/MXPA03009448A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040235804A1 (en) | 2004-11-25 |
| CA2472309A1 (en) | 2002-10-24 |
| WO2002083146A1 (en) | 2002-10-24 |
| US7820706B2 (en) | 2010-10-26 |
| WO2002083239A1 (en) | 2002-10-24 |
| CA2472309C (en) | 2010-12-07 |
| BR0208955A (pt) | 2004-10-19 |
| MXPA03009448A (es) | 2004-05-24 |
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|---|---|---|---|
| FB | Suspension of granting procedure |