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AR023271A1 - Conjugado polimerico capaz de inhibir una o mas enzimas proteoliticas - Google Patents

Conjugado polimerico capaz de inhibir una o mas enzimas proteoliticas

Info

Publication number
AR023271A1
AR023271A1 ARP000104756A ARP000104756A AR023271A1 AR 023271 A1 AR023271 A1 AR 023271A1 AR P000104756 A ARP000104756 A AR P000104756A AR P000104756 A ARP000104756 A AR P000104756A AR 023271 A1 AR023271 A1 AR 023271A1
Authority
AR
Argentina
Prior art keywords
enzymes
proteolitical
inhibit
polymeric
polymer conjugate
Prior art date
Application number
ARP000104756A
Other languages
English (en)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of AR023271A1 publication Critical patent/AR023271A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Conjugados poliméricos apropiados para el uso en la prevencion de la irritacion cutánea que se produce por la exposicion de la piel a los fluidoscorporales, inter alia, el fluido menstrual. Conjugados poliméricos que tienen la formula (1), en donde Tes una unidad heterocíclica que es capaz de inhibiruna o más enzimas proteolíticas; L es un grupo de enlace; [Poli] es una unidad polimérica, i representa el numero de dichas unidades heterocíclicas quecomprenden el conjugado y tiene un valor desde1 hasta 100; z es 0 o 1, en donde los conjugados poliméricos. Campo de aplicacion: Panales, rellenos, toallassanitarias y artículos similares.
ARP000104756A 1999-09-10 2000-09-11 Conjugado polimerico capaz de inhibir una o mas enzimas proteoliticas AR023271A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15341899P 1999-09-10 1999-09-10

Publications (1)

Publication Number Publication Date
AR023271A1 true AR023271A1 (es) 2002-09-04

Family

ID=22547144

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP000104757A AR022655A1 (es) 1999-09-10 2000-09-11 Composiciones para inhibir enzimas, aplicables a la piel humana y para prevenir irritacion de la piel y metodo para prevenir irritacion de la piel.
ARP000104756A AR023271A1 (es) 1999-09-10 2000-09-11 Conjugado polimerico capaz de inhibir una o mas enzimas proteoliticas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP000104757A AR022655A1 (es) 1999-09-10 2000-09-11 Composiciones para inhibir enzimas, aplicables a la piel humana y para prevenir irritacion de la piel y metodo para prevenir irritacion de la piel.

Country Status (9)

Country Link
US (1) US6541629B1 (es)
EP (2) EP1212097B1 (es)
JP (1) JP5020451B2 (es)
AR (2) AR022655A1 (es)
AT (2) ATE309824T1 (es)
AU (2) AU7125700A (es)
DE (2) DE60044827D1 (es)
PE (2) PE20010586A1 (es)
WO (2) WO2001017565A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803496B2 (en) * 1997-09-10 2004-10-12 The Procter & Gamble Company Method for maintaining or improving skin health
US8907154B2 (en) 2001-10-01 2014-12-09 The Procter & Gamble Company Sanitary napkins with hydrophobic lotions
US8795716B2 (en) 2001-10-01 2014-08-05 The Procter & Gamble Company Skin care compositions on a thin sanitary napkin
US9035123B2 (en) 2002-10-01 2015-05-19 The Procter & Gamble Company Absorbent article having a lotioned topsheet
US7285570B2 (en) 2003-04-17 2007-10-23 The Procter & Gamble Company Compositions and methods for regulating mammalian keratinous tissue
KR101099409B1 (ko) * 2003-06-06 2011-12-27 아렉시스 악티에볼라그 피부 상태 또는 암 치료를 위한 ｓｃｃｅ 저해제로서의융합된 헤테로사이클 화합물의 용도
US7384113B2 (en) * 2004-04-19 2008-06-10 Hewlett-Packard Development Company, L.P. Fluid ejection device with address generator
US7265257B2 (en) * 2004-08-10 2007-09-04 Kimberly-Clark Worldwide, Inc. Absorbent articles comprising a bodily exudate modifying agent and a film-forming skin care formulation
US7642397B2 (en) * 2004-08-10 2010-01-05 Kimberly-Clark Worldwide, Inc. Absorbent articles comprising a bodily exudate modifying agent and a skin care formulation
BRPI0908393A2 (pt) * 2008-02-15 2015-08-11 Procter & Gamble Artigo absorvente com loção que compreende um material de polipropileno glicol
CN104583228B (zh) * 2012-08-24 2018-09-28 味之素株式会社 酰基二肽衍生物
JP7404031B2 (ja) 2019-10-29 2023-12-25 日本航空電子工業株式会社 アンテナ

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2211469A1 (en) 1972-12-21 1974-07-19 Air Liquide Enzyme purification, esp. ribonuclease, and (chymo) trypsin - by treatment with specific polyinhibitors and extraction or pptn of the complex formed
DE2433883C2 (de) * 1973-07-20 1986-03-27 Research Corp., New York, N.Y. Verwendung von physiologisch aktiven Polypeptiden
FR2252351A2 (en) 1973-11-28 1975-06-20 Air Liquide Isolation of enzymes by selective extraction - partition of polyinhibitor-enzyme complex between water and polyethylene glycol
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US5162307A (en) 1988-09-09 1992-11-10 Board Of Trustees Of The University Of Kentucky Polymer bound elastase inhibitors
FR2651125B1 (fr) * 1989-08-23 1992-10-02 Roussel Uclaf Compositions pharmaceutiques de type "pates a l'eau".
DE69120141T2 (de) 1990-03-28 1996-11-28 Shuji Kojima Polymerkombiniertes Arzneimittel zur Magenbehandlung und Verfahren zu dessen Herstellung
JPH04182423A (ja) * 1990-11-16 1992-06-30 Shiseido Co Ltd 清浄・清拭剤組成物
US5880131A (en) 1993-10-20 1999-03-09 Enzon, Inc. High molecular weight polymer-based prodrugs
US5919455A (en) 1993-10-27 1999-07-06 Enzon, Inc. Non-antigenic branched polymer conjugates
DE4342154A1 (de) 1993-12-10 1995-06-14 Behringwerke Ag Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel als Antikoagulantien
JP3945544B2 (ja) * 1995-12-27 2007-07-18 ピジョン株式会社 ダイズエキスの製造方法
CA2277618A1 (en) * 1997-01-10 1998-07-16 Novo Nordisk A/S Enzyme coupled with polymeric molecules for skin care
US5965119A (en) * 1997-12-30 1999-10-12 Enzon, Inc. Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
US6267952B1 (en) * 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
WO1999045974A1 (en) * 1998-03-12 1999-09-16 The Procter & Gamble Company Protease inhibitors in absorbent articles
HUP0101070A2 (hu) * 1998-03-12 2001-07-30 The Procter & Gamble Co. Enziminhibitort tartalmazó bőrápoló készítménnyel ellátott eldobható abszorbens cikkek
US6066673A (en) * 1998-03-12 2000-05-23 The Procter & Gamble Company Enzyme inhibitors
US6627228B1 (en) 1999-01-08 2003-09-30 Emisphere Technologies, Inc. Polymeric delivery agents and delivery agents compounds
PE20010588A1 (es) * 1999-09-10 2001-06-23 Procter & Gamble Conjugados polimericos inhibidores de enzimas proteoliticas y lipoliticas
EP1212034A1 (en) * 1999-09-10 2002-06-12 The Procter & Gamble Company Enzyme inhibitors

Also Published As

Publication number Publication date
DE60024101T2 (de) 2006-07-27
JP2003508498A (ja) 2003-03-04
ATE309824T1 (de) 2005-12-15
AU7125700A (en) 2001-04-10
EP1212097A2 (en) 2002-06-12
EP1438073A2 (en) 2004-07-21
EP1438073B1 (en) 2010-08-11
EP1212097B1 (en) 2005-11-16
WO2001017565A3 (en) 2002-01-17
US6541629B1 (en) 2003-04-01
PE20010586A1 (es) 2001-06-23
PE20010587A1 (es) 2001-07-07
WO2001017564A3 (en) 2002-01-24
AU7126900A (en) 2001-04-10
DE60024101D1 (de) 2005-12-22
ATE476998T1 (de) 2010-08-15
AR022655A1 (es) 2002-09-04
WO2001017564A2 (en) 2001-03-15
WO2001017565A2 (en) 2001-03-15
DE60044827D1 (de) 2010-09-23
JP5020451B2 (ja) 2012-09-05

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