AR029085A1 - Composiciones que contienen un derivado benzamina para tratar enfermedades alergicas - Google Patents
Composiciones que contienen un derivado benzamina para tratar enfermedades alergicasInfo
- Publication number
- AR029085A1 AR029085A1 ARP010102304A ARP010102304A AR029085A1 AR 029085 A1 AR029085 A1 AR 029085A1 AR P010102304 A ARP010102304 A AR P010102304A AR P010102304 A ARP010102304 A AR P010102304A AR 029085 A1 AR029085 A1 AR 029085A1
- Authority
- AR
- Argentina
- Prior art keywords
- substituted
- alkyl
- compositions containing
- derivative
- treat
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical class NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 title 1
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 201000008736 Systemic mastocytosis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000002019 disulfides Chemical class 0.000 abstract 1
- 210000005069 ears Anatomy 0.000 abstract 1
- 210000001508 eye Anatomy 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 210000001595 mastoid Anatomy 0.000 abstract 1
- 210000001331 nose Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Uso de un derivado disulfuro de formula 1 en la cual X es C (=O) û N (-R1) û R; R y R1 son independientemente H; fenilo (no) sustituido; bencilo (no) sustituido; o alquenilo o alquilo C1-8 opcionalmente sustituido con o terminados en OH, OR2, NR3R4; cicloalquilo C4-7; arilo (no) sustituido, o anillo heterociclico de 5-7 miembros (no) sustituidos; donde los sustituyentes opcionales están seleccionados del grupo que consiste en alcoxi o alquilo C1-6; halogeno; OH; CN; CF3; NO2 y CO2R2; R2 = alquilo C1-3 y R3 y R4 son independientemente H; bencilo; alquilo o alquenilo C1-8; cicloalquilo C4-7; arilo (no) sustituido; o un anillo heterocíclico de 5 û 7 miembros (no) sustituido; donde los sustituyentes opcionales están seleccionados del grupo que consiste en alcoxi o alquilo C1-6; halogeno; OH, CN, CF3, NO2 y CO2R2 para la preparacion de una composicion farmacéutica para prevenir o tratar una enfermedad alérgica de los ojos, nariz, piel, oídos, tracto gastrointestinal o pulmones y prevenir o tratar manifestaciones de mastocitosis sistémica y dichas composiciones que contienen un derivado disulfuro estabilizador de células mastoides como ingrediente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20608300P | 2000-05-19 | 2000-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029085A1 true AR029085A1 (es) | 2003-06-04 |
Family
ID=22764902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010102304A AR029085A1 (es) | 2000-05-19 | 2001-05-15 | Composiciones que contienen un derivado benzamina para tratar enfermedades alergicas |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6492418B2 (es) |
| EP (1) | EP1284722B1 (es) |
| JP (1) | JP2003534274A (es) |
| KR (1) | KR20020093981A (es) |
| CN (1) | CN1172666C (es) |
| AR (1) | AR029085A1 (es) |
| AT (1) | ATE302601T1 (es) |
| AU (2) | AU2001253807B2 (es) |
| BR (1) | BR0110852A (es) |
| CA (1) | CA2407767A1 (es) |
| DE (1) | DE60112922T2 (es) |
| DK (1) | DK1284722T3 (es) |
| ES (1) | ES2243482T3 (es) |
| HK (1) | HK1049614B (es) |
| MX (1) | MXPA02011482A (es) |
| PL (1) | PL363102A1 (es) |
| PT (1) | PT1284722E (es) |
| WO (1) | WO2001089493A2 (es) |
| ZA (1) | ZA200208838B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2222370T3 (es) * | 2000-05-19 | 2005-02-01 | Alcon Inc. | Derivados de disulfuro de anilina para tratar enfermedades alergicas. |
| KR20070024618A (ko) * | 2004-06-28 | 2007-03-02 | 알콘, 인코퍼레이티드 | 알레르기성 질환 치료용 국소 제제 |
| KR100984814B1 (ko) | 2009-12-21 | 2010-10-01 | 삼성전자주식회사 | 수평형 사출 금형 시스템 및 이를 이용하는 사출 성형 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1232787A (es) | 1967-08-08 | 1971-05-19 | ||
| US3663616A (en) | 1969-10-13 | 1972-05-16 | Sherwin Williams Co | Bis(2-carbamylphenyl)disulfides |
| EP0000627B1 (en) * | 1977-07-09 | 1982-09-01 | Michael Fred Joyce | Carriers for containers, apparatus and method for applying same to containers |
| JPS55324A (en) * | 1978-06-16 | 1980-01-05 | Kyowa Hakko Kogyo Co Ltd | Antithrombotic |
| EP0006227B1 (en) | 1978-06-16 | 1984-12-27 | Kyowa Hakko Kogyo Co., Ltd | Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| GB9020933D0 (en) | 1990-09-26 | 1990-11-07 | Ici Plc | Compound,preparation and use |
| US5859017A (en) | 1994-04-01 | 1999-01-12 | Cell Therapeutics, Inc. | Method for inhibiting mast cell and basophil activation |
| US5734081A (en) | 1994-08-05 | 1998-03-31 | Warner-Lambert Company | Arylthio compounds |
| US5463122A (en) | 1994-08-05 | 1995-10-31 | Warner-Lambert Company | Arylthio compounds |
| US6001555A (en) | 1994-09-23 | 1999-12-14 | The United States Of America As Represented By The Department Of Health And Human Services | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein |
| JPH095926A (ja) | 1995-04-18 | 1997-01-10 | Fuji Photo Film Co Ltd | 熱現像感光材料 |
| US5641805A (en) | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| AU2458697A (en) | 1996-04-18 | 1997-11-07 | Alcon Laboratories, Inc. | Calcium channel blockers as human conjunctival mast cell degranulation inhibitors for treating ocular allergic conditions |
| JP2894445B2 (ja) | 1997-02-12 | 1999-05-24 | 日本たばこ産業株式会社 | Ｃｅｔｐ活性阻害剤として有効な化合物 |
| JP3940201B2 (ja) * | 1997-05-20 | 2007-07-04 | 大塚製薬株式会社 | ３，３’−ジチオジベンゾヒドロキサム酸 |
-
2001
- 2001-04-25 AT AT01927346T patent/ATE302601T1/de not_active IP Right Cessation
- 2001-04-25 CA CA002407767A patent/CA2407767A1/en not_active Abandoned
- 2001-04-25 AU AU2001253807A patent/AU2001253807B2/en not_active Ceased
- 2001-04-25 HK HK03101587.4A patent/HK1049614B/en not_active IP Right Cessation
- 2001-04-25 PT PT01927346T patent/PT1284722E/pt unknown
- 2001-04-25 AU AU5380701A patent/AU5380701A/xx active Pending
- 2001-04-25 PL PL01363102A patent/PL363102A1/xx not_active Application Discontinuation
- 2001-04-25 MX MXPA02011482A patent/MXPA02011482A/es active IP Right Grant
- 2001-04-25 EP EP01927346A patent/EP1284722B1/en not_active Expired - Lifetime
- 2001-04-25 DE DE60112922T patent/DE60112922T2/de not_active Expired - Fee Related
- 2001-04-25 ES ES01927346T patent/ES2243482T3/es not_active Expired - Lifetime
- 2001-04-25 DK DK01927346T patent/DK1284722T3/da active
- 2001-04-25 JP JP2001585738A patent/JP2003534274A/ja not_active Ceased
- 2001-04-25 CN CNB018094767A patent/CN1172666C/zh not_active Expired - Fee Related
- 2001-04-25 KR KR1020027014930A patent/KR20020093981A/ko not_active Withdrawn
- 2001-04-25 WO PCT/US2001/013399 patent/WO2001089493A2/en not_active Ceased
- 2001-04-25 BR BR0110852-2A patent/BR0110852A/pt not_active IP Right Cessation
- 2001-04-25 US US09/843,131 patent/US6492418B2/en not_active Expired - Fee Related
- 2001-05-15 AR ARP010102304A patent/AR029085A1/es not_active Application Discontinuation
-
2002
- 2002-10-31 ZA ZA200208838A patent/ZA200208838B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1429107A (zh) | 2003-07-09 |
| ES2243482T3 (es) | 2005-12-01 |
| CA2407767A1 (en) | 2001-11-29 |
| DK1284722T3 (da) | 2005-09-19 |
| US6492418B2 (en) | 2002-12-10 |
| JP2003534274A (ja) | 2003-11-18 |
| PL363102A1 (en) | 2004-11-15 |
| AU5380701A (en) | 2001-12-03 |
| WO2001089493A2 (en) | 2001-11-29 |
| DE60112922T2 (de) | 2006-01-26 |
| WO2001089493A3 (en) | 2002-03-28 |
| BR0110852A (pt) | 2003-02-11 |
| AU2001253807B2 (en) | 2005-02-17 |
| PT1284722E (pt) | 2005-10-31 |
| DE60112922D1 (de) | 2005-09-29 |
| EP1284722A2 (en) | 2003-02-26 |
| HK1049614A1 (en) | 2003-05-23 |
| MXPA02011482A (es) | 2003-06-06 |
| CN1172666C (zh) | 2004-10-27 |
| ZA200208838B (en) | 2003-10-31 |
| HK1049614B (en) | 2005-11-18 |
| EP1284722B1 (en) | 2005-08-24 |
| ATE302601T1 (de) | 2005-09-15 |
| KR20020093981A (ko) | 2002-12-16 |
| US20020065281A1 (en) | 2002-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |