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AR028476A1 - Tratamiento del cancer - Google Patents

Tratamiento del cancer

Info

Publication number
AR028476A1
AR028476A1 ARP000102321A ARP000102321A AR028476A1 AR 028476 A1 AR028476 A1 AR 028476A1 AR P000102321 A ARP000102321 A AR P000102321A AR P000102321 A ARP000102321 A AR P000102321A AR 028476 A1 AR028476 A1 AR 028476A1
Authority
AR
Argentina
Prior art keywords
cancer treatment
cancer
treatment
Prior art date
Application number
ARP000102321A
Other languages
English (en)
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9911183.3A external-priority patent/GB9911183D0/en
Priority claimed from GBGB9911346.6A external-priority patent/GB9911346D0/en
Priority claimed from GBGB9918534.0A external-priority patent/GB9918534D0/en
Priority claimed from GBGB9927005.0A external-priority patent/GB9927005D0/en
Priority claimed from GBGB9927106.6A external-priority patent/GB9927106D0/en
Priority claimed from GB0007637A external-priority patent/GB0007637D0/en
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of AR028476A1 publication Critical patent/AR028476A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ARP000102321A 1999-05-13 2000-05-15 Tratamiento del cancer AR028476A1 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9911183.3A GB9911183D0 (en) 1999-05-13 1999-05-13 Treatment of cancers
GBGB9911346.6A GB9911346D0 (en) 1999-05-14 1999-05-14 Treatment of cancers
GBGB9918534.0A GB9918534D0 (en) 1999-08-05 1999-08-05 Treatment of cancers
GBGB9927005.0A GB9927005D0 (en) 1999-11-15 1999-11-15 Treatment of cancers
GBGB9927106.6A GB9927106D0 (en) 1999-11-16 1999-11-16 Cancer treatment
GB0007637A GB0007637D0 (en) 2000-03-29 2000-03-29 Antitumour compound

Publications (1)

Publication Number Publication Date
AR028476A1 true AR028476A1 (es) 2003-05-14

Family

ID=27546594

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102321A AR028476A1 (es) 1999-05-13 2000-05-15 Tratamiento del cancer

Country Status (32)

Country Link
US (1) US8119638B2 (es)
EP (3) EP1176964B8 (es)
JP (2) JP2002544231A (es)
KR (1) KR20020019914A (es)
CN (2) CN100477993C (es)
AR (1) AR028476A1 (es)
AT (3) ATE338552T1 (es)
AU (2) AU777417B2 (es)
BG (1) BG65680B1 (es)
BR (1) BR0010531A (es)
CA (1) CA2373794C (es)
CY (4) CY1105818T1 (es)
CZ (1) CZ301482B6 (es)
DE (4) DE60030554T8 (es)
DK (3) DK1702618T3 (es)
ES (2) ES2272279T3 (es)
FR (1) FR08C0013I2 (es)
HU (2) HU229866B1 (es)
IL (2) IL146434A0 (es)
LU (1) LU91418I2 (es)
MX (1) MXPA01011562A (es)
MY (1) MY164077A (es)
NL (1) NL300337I2 (es)
NO (2) NO324564B1 (es)
NZ (1) NZ515423A (es)
PL (1) PL198185B1 (es)
PT (3) PT1176964E (es)
SI (3) SI1176964T1 (es)
SK (1) SK287580B6 (es)
TR (1) TR200103819T2 (es)
UA (1) UA74782C2 (es)
WO (1) WO2000069441A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MXPA02011319A (es) 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
JP4391083B2 (ja) * 2000-11-06 2009-12-24 ファルマ・マール・ソシエダード・アノニマ 効果的な抗腫瘍治療
GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
US20050004018A1 (en) * 2001-10-19 2005-01-06 Jose Jimeno Use of antitumoral compound in cancer therapy
GB0202544D0 (en) 2002-02-04 2002-03-20 Pharma Mar Sa The synthesis of naturally occuring ecteinascidins and related compounds
GB0312407D0 (en) * 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) * 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
DK1689404T3 (da) * 2003-11-13 2009-01-26 Pharma Mar Sau Kombination af et-743 med 5-fluoracil-prodrugs til behandling af cancer
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
WO2005049030A1 (en) * 2003-11-14 2005-06-02 Pharma Mar, S.A. Combination therapy comprising the use of et-743 and paclitaxel for treating cancer
CA2573072A1 (en) * 2004-07-09 2006-01-19 Rafael Rosell Costa Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
WO2006046080A2 (en) * 2004-10-26 2006-05-04 Pharma Mar S.A., Sociedad Unipersonal Pegylated liposomal doxorubicin in combination with ecteinescidin 743
SI1658848T1 (sl) * 2004-10-29 2007-12-31 Pharma Mar Sa Formulacije vsebujoäśe ekteinascidin in disaharid
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
AU2007249281A1 (en) * 2006-05-12 2007-11-22 Pharma Mar, S.A. Anticancer treatments with a combination of docetaxel and ecteinascidin
EP2201141A1 (en) * 2007-10-19 2010-06-30 Pharma Mar S.A. Prognostic molecular markers for et-743 treatment
AU2017215603A1 (en) * 2016-02-04 2018-08-09 Jiangsu Hengrui Medicine Co., Ltd. Trabectedin-inclusive injectable pharmaceutical composition for gastrointestinal external use and method for manufacturing the same
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
CN112574234B (zh) * 2019-09-27 2022-05-24 江苏恒瑞医药股份有限公司 一种海鞘素衍生物的制备方法
AU2021256746A1 (en) 2020-04-15 2022-11-03 Ever Valinject Gmbh Composition comprising trabectedin and an amino acid
EP3960177A1 (en) * 2020-08-26 2022-03-02 Anturec Pharmaceuticals GmbH Composition comprising ttf-ngr for use in treating soft-tissue sarcoma
US12303506B2 (en) 2022-01-20 2025-05-20 Extrovis Ag Trabectedin composition

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US5256663A (en) 1986-06-09 1993-10-26 The Board Of Trustees Of The University Of Illinois Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
DE3774435D1 (de) * 1986-06-09 1991-12-12 Univ Pennsylvania Ekteinascidine 729, 743, 745, 759a, 759b and 770.
US5089273A (en) * 1986-06-09 1992-02-18 Board Of Trustees Of The University Of Illinois Ecteinascidins 729, 743, 745, 759A, 759B and 770
DE3635711A1 (de) * 1986-10-21 1988-04-28 Knoll Ag 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
GB8805268D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
GB9101221D0 (en) * 1991-01-19 1991-02-27 Smithkline Beecham Plc Pharmaceuticals
US5721352A (en) 1991-02-19 1998-02-24 University Of Florida Research Foundation Entomopoxvirus expression system
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US5891704A (en) * 1992-11-19 1999-04-06 Anticancer, Inc. Method to produce high levels of methioninase
JPH09503743A (ja) * 1993-05-14 1997-04-15 デポテック コーポレーション 神経学的疾患の治療方法
US5478932A (en) * 1993-12-02 1995-12-26 The Board Of Trustees Of The University Of Illinois Ecteinascidins
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GB9508195D0 (en) * 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
US5721362A (en) * 1996-09-18 1998-02-24 President And Fellows Of Harvard College Process for producing ecteinascidin compounds
ES2313154T3 (es) * 1996-11-05 2009-03-01 The Children's Medical Center Corporation Composiciones que comprenden talodimina y dexametasona para el tratamiento de cancer.
IL123740A0 (en) * 1997-03-28 1998-10-30 Pfizer NK-1 receptor antagonists for the treatment of delayed emesis
US5985876A (en) * 1997-04-15 1999-11-16 Univ Illinois Nucleophile substituted ecteinascidins and N-oxide ecteinascidins
DE19720312A1 (de) * 1997-05-15 1998-11-19 Hoechst Ag Zubereitung mit erhöhter in vivo Verträglichkeit
GB9801231D0 (en) * 1997-06-05 1998-03-18 Merck & Co Inc A method of treating cancer
IL138856A0 (en) * 1998-04-06 2001-10-31 Univ Illinois Semi-synthetic ecteinascidins
CA2331593C (en) * 1998-05-11 2008-08-05 Pharma Mar, S.A. Metabolites of ecteinascidin 743
US6124292A (en) * 1998-09-30 2000-09-26 President And Fellows Of Harvard College Synthetic analogs of ecteinascidin-743
MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MY130271A (en) * 1999-05-14 2007-06-29 Pharma Mar Sa Hemisynthetic method and new compounds
CA2406080C (en) 2000-04-12 2011-11-29 Pharma Mar, S.A. Antitumoral ecteinascidin derivatives
US7247892B2 (en) * 2000-04-24 2007-07-24 Taylor Geoff W Imaging array utilizing thyristor-based pixel elements
MXPA02011319A (es) * 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
US7420051B2 (en) * 2000-05-15 2008-09-02 Pharma Mar, S.A. Synthetic process for the manufacture of an ecteinaschidin compound
AU2001281232A1 (en) * 2000-08-11 2002-02-25 City Of Hope The anti-neoplastic agent ET-743 inhibits trans activation by SXR
JP4391083B2 (ja) 2000-11-06 2009-12-24 ファルマ・マール・ソシエダード・アノニマ 効果的な抗腫瘍治療
EP1360337A1 (en) 2001-02-09 2003-11-12 The Regents Of The University Of California Ecteinascidin family compounds: compositions and methods
AU2002242561A1 (en) 2001-03-30 2002-10-15 Shire Biochem Inc. Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine
GB0121285D0 (en) 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
US20050004018A1 (en) * 2001-10-19 2005-01-06 Jose Jimeno Use of antitumoral compound in cancer therapy
US20040019027A1 (en) * 2002-04-12 2004-01-29 Barry Forman Method of treating cerebrotendinous xanthomatosis
GB0312407D0 (en) * 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) * 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
DK1689404T3 (da) 2003-11-13 2009-01-26 Pharma Mar Sau Kombination af et-743 med 5-fluoracil-prodrugs til behandling af cancer
WO2005049030A1 (en) 2003-11-14 2005-06-02 Pharma Mar, S.A. Combination therapy comprising the use of et-743 and paclitaxel for treating cancer
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
CA2573072A1 (en) * 2004-07-09 2006-01-19 Rafael Rosell Costa Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
WO2006035244A2 (en) 2004-09-29 2006-04-06 Pharma Mar S.A., Sociedad Unipersonal Ecteinascidin compounds as anti -inflammatory agents
WO2006046080A2 (en) 2004-10-26 2006-05-04 Pharma Mar S.A., Sociedad Unipersonal Pegylated liposomal doxorubicin in combination with ecteinescidin 743
SI1658848T1 (sl) * 2004-10-29 2007-12-31 Pharma Mar Sa Formulacije vsebujoäśe ekteinascidin in disaharid
WO2007062413A2 (en) * 2005-11-25 2007-05-31 University Of Medicine And Dentistry Of New Jersey Use of parp-1 inhibitors
AU2007249281A1 (en) * 2006-05-12 2007-11-22 Pharma Mar, S.A. Anticancer treatments with a combination of docetaxel and ecteinascidin

Also Published As

Publication number Publication date
EP1702618A3 (en) 2006-12-27
DE60030554T8 (de) 2008-01-10
DE60045720D1 (de) 2011-04-21
DE122008000013I1 (de) 2008-08-07
UA74782C2 (uk) 2006-02-15
NO2008005I2 (es) 2010-09-27
CY1112753T1 (el) 2016-02-10
NO324564B1 (no) 2007-11-19
FR08C0013I2 (fr) 2009-10-30
ES2294756T3 (es) 2008-04-01
NL300337I2 (nl) 2008-09-01
CY2008007I1 (el) 2009-11-04
EP1702618B1 (en) 2007-10-17
NO20015516D0 (no) 2001-11-12
FR08C0013I1 (es) 2008-05-30
CA2373794C (en) 2005-10-11
MXPA01011562A (es) 2002-07-30
BR0010531A (pt) 2002-06-04
EP1176964B8 (en) 2007-10-10
EP1176964B1 (en) 2006-09-06
BG65680B1 (bg) 2009-06-30
DK1176964T3 (da) 2007-01-15
DK1716853T3 (da) 2011-06-27
CN100477993C (zh) 2009-04-15
PL352931A1 (en) 2003-09-22
JP2002544231A (ja) 2002-12-24
NL300337I1 (nl) 2008-05-01
CA2373794A1 (en) 2000-11-23
EP1176964A1 (en) 2002-02-06
CZ20014081A3 (cs) 2002-11-13
ATE375795T1 (de) 2007-11-15
DE60036826T2 (de) 2008-08-28
PT1702618E (pt) 2008-01-11
CY1105818T1 (el) 2011-02-02
AU2005200180B9 (en) 2008-05-29
SK287580B6 (sk) 2011-03-04
AU2005200180A1 (en) 2005-02-10
DE60030554D1 (de) 2006-10-19
US20070275942A1 (en) 2007-11-29
EP1702618A2 (en) 2006-09-20
HUS1500001I1 (hu) 2016-08-29
JP2012149095A (ja) 2012-08-09
MY164077A (en) 2017-11-30
CY2008007I2 (el) 2009-11-04
LU91418I2 (fr) 2008-05-13
AU4597500A (en) 2000-12-05
AU2005200180B2 (en) 2007-12-13
CZ301482B6 (cs) 2010-03-17
IL146434A (en) 2008-03-20
HUP0201187A3 (en) 2002-11-28
HUP0201187A2 (en) 2002-09-28
HU229866B1 (en) 2014-10-28
EP1716853B1 (en) 2011-03-09
EP1716853B9 (en) 2011-09-28
DE60030554T2 (de) 2007-09-13
ES2272279T3 (es) 2007-05-01
IL146434A0 (en) 2002-07-25
ATE338552T1 (de) 2006-09-15
WO2000069441A1 (en) 2000-11-23
TR200103819T2 (tr) 2002-04-22
LU91418I9 (es) 2019-01-02
SK16442001A3 (sk) 2002-03-05
PL198185B1 (pl) 2008-06-30
PT1716853E (pt) 2011-05-12
PT1176964E (pt) 2007-01-31
AU777417B2 (en) 2004-10-14
SI1716853T1 (sl) 2011-10-28
SI1176964T1 (sl) 2007-02-28
DK1702618T3 (da) 2008-02-25
SI1702618T1 (sl) 2008-02-29
EP1716853A2 (en) 2006-11-02
CY1107143T1 (el) 2010-07-28
JP5777562B2 (ja) 2015-09-09
NO2008005I1 (no) 2008-06-09
CN1360503A (zh) 2002-07-24
CN1679631A (zh) 2005-10-12
BG106171A (en) 2002-06-28
NZ515423A (en) 2004-04-30
ATE500830T1 (de) 2011-03-15
EP1716853A3 (en) 2006-11-15
KR20020019914A (ko) 2002-03-13
DE60036826D1 (de) 2007-11-29
NO20015516L (no) 2002-01-11
US8119638B2 (en) 2012-02-21

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