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AR027327A1 - Procedimiento para la separacion einzimatica de racematos de derivados de aminometil-aril-ciclohezanol - Google Patents

Procedimiento para la separacion einzimatica de racematos de derivados de aminometil-aril-ciclohezanol

Info

Publication number
AR027327A1
AR027327A1 ARP010100415A ARP010100415A AR027327A1 AR 027327 A1 AR027327 A1 AR 027327A1 AR P010100415 A ARP010100415 A AR P010100415A AR P010100415 A ARP010100415 A AR P010100415A AR 027327 A1 AR027327 A1 AR 027327A1
Authority
AR
Argentina
Prior art keywords
derivatives
separation
einzymatic
ciclohezanol
aminometil
Prior art date
Application number
ARP010100415A
Other languages
English (en)
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7629816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR027327(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of AR027327A1 publication Critical patent/AR027327A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento para la separacion enzimática de racematos de derivados de aminometil-aril-ciclohexanol.
ARP010100415A 2000-02-04 2001-01-30 Procedimiento para la separacion einzimatica de racematos de derivados de aminometil-aril-ciclohezanol AR027327A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10004926A DE10004926A1 (de) 2000-02-04 2000-02-04 Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten

Publications (1)

Publication Number Publication Date
AR027327A1 true AR027327A1 (es) 2003-03-26

Family

ID=7629816

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010100415A AR027327A1 (es) 2000-02-04 2001-01-30 Procedimiento para la separacion einzimatica de racematos de derivados de aminometil-aril-ciclohezanol

Country Status (20)

Country Link
US (1) US7168937B2 (es)
EP (1) EP1252327B1 (es)
JP (1) JP2003528049A (es)
AR (1) AR027327A1 (es)
AT (1) ATE274599T1 (es)
AU (2) AU2001230192B2 (es)
CA (1) CA2399819C (es)
CO (1) CO5271656A1 (es)
DE (2) DE10004926A1 (es)
DK (1) DK1252327T3 (es)
ES (1) ES2227118T3 (es)
HU (1) HUP0204430A3 (es)
MX (1) MXPA02007594A (es)
NZ (1) NZ521087A (es)
PE (1) PE20011075A1 (es)
PT (1) PT1252327E (es)
SI (1) SI1252327T1 (es)
TR (1) TR200402470T4 (es)
UY (1) UY26574A1 (es)
WO (1) WO2001057232A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049481A1 (de) 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte C-Cyclohexylmethylamin-Derivate
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10059411A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
ATE465726T1 (de) * 2002-11-22 2010-05-15 Gruenenthal Gmbh Verwendung von (1r, 2r)-3-(3-dimenthylamino-1- ethyl-2-methyl-propyl)-phenol zur behandlung von entzündungsschmerz
US7094795B2 (en) 2003-02-27 2006-08-22 Sanofi-Aventis Deutschland Gmbh Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
DE10308350B4 (de) * 2003-02-27 2006-06-01 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
US20060211887A1 (en) * 2005-02-25 2006-09-21 Gruenenthal Gmbh Phosphate salts of 6-dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexane compounds
DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN162851B (es) * 1980-09-19 1988-07-16 Pfizer
JP3049403B2 (ja) 1991-11-01 2000-06-05 チッソ株式会社 光学活性トランス−２−アリール−１−シクロヘキサノール誘導体およびその製造法
CA2068038A1 (en) * 1991-05-08 1992-11-09 Christopher Yee Enzymatic resolution of .alpha.-tertiary carboxylic acid esters
PT552041E (pt) 1992-01-15 2000-12-29 Squibb & Sons Inc Processo enzimaticos para a resolucao de misturas enantiomericas de compostos uteis como intermediarios para a preparacao de taxanos
DE4217506A1 (de) 1992-05-27 1993-12-02 Boehringer Mannheim Gmbh Mikrobielle Esterase zur enantioselektiven Spaltung von 1-Arylalkylestern
ES2046950B1 (es) 1992-06-08 1994-10-01 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil)propionico por hidrolisis enantioselectiva catalizada enzimaticamente.
JPH07101921A (ja) 1993-10-01 1995-04-18 Chisso Corp 光学活性トリフルオロメチルベンジルアルコール誘導体およびその製造法
DE4414273A1 (de) 1994-04-23 1995-10-26 Chemie Linz Deutschland Enzymatische Racematspaltung asymmetrischer Alkohole mittels Vinylestern mehrbasiger Carbonsäuren
US5696299A (en) 1994-10-26 1997-12-09 The Nisshin Oil Mills, Ltd. Optical resolution for producing optically active alcohol
US5770438A (en) * 1994-11-01 1998-06-23 Takeda Chemical Industries, Ltd. Process for enantioselective hydrolysis of α-(2-amino)-phenyl-benzenemethanol ester type compounds using bacillus, pseudomonas or streptomyces
JPH08322590A (ja) 1995-06-05 1996-12-10 Chisso Corp 光学活性２ー（１−ナフチル）シクロヘキサン−１−オール誘導体及びその製造方法
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
JPH09121564A (ja) 1995-10-27 1997-05-06 Kasei Optonix Co Ltd 静電アクチュエータ
DE19547766A1 (de) * 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
CN1251987A (zh) * 1997-03-11 2000-05-03 达尔文发现有限公司 含有r－和s－对映体分离部分的剂型

Also Published As

Publication number Publication date
CA2399819C (en) 2011-04-12
HUP0204430A3 (en) 2005-05-30
WO2001057232B1 (de) 2002-01-10
HK1051558A1 (en) 2003-08-08
DK1252327T3 (da) 2004-11-01
PE20011075A1 (es) 2001-12-29
EP1252327B1 (de) 2004-08-25
WO2001057232A1 (de) 2001-08-09
DE50103394D1 (de) 2004-09-30
PT1252327E (pt) 2004-12-31
JP2003528049A (ja) 2003-09-24
NZ521087A (en) 2005-11-25
AU3019201A (en) 2001-08-14
ES2227118T3 (es) 2005-04-01
ATE274599T1 (de) 2004-09-15
MXPA02007594A (es) 2002-12-13
CA2399819A1 (en) 2001-08-09
HUP0204430A2 (en) 2003-05-28
AU2001230192B2 (en) 2006-07-13
US20030186396A1 (en) 2003-10-02
SI1252327T1 (en) 2004-12-31
EP1252327A1 (de) 2002-10-30
UY26574A1 (es) 2001-04-30
TR200402470T4 (tr) 2004-12-21
US7168937B2 (en) 2007-01-30
CO5271656A1 (es) 2003-04-30
DE10004926A1 (de) 2001-08-09

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